[Hub]/) : Traits : Irritable Bowel Disease (IBD) :

chr1:66,697,368-68,559,650

Best TWAS P=2.46e-49 · Best GWAS P=4.82e-111 conditioned to 7.16e-68

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 NTR Blood IL12RB2 0.04 0.02 bslmm 539 0.02 1.9e-08 -5.0 -6.1 1.2e-09 0.18 1.00 0.00 TRUE
2 NTR Blood MIER1 0.03 0.01 bslmm 573 0.01 2.7e-05 -1.5 -7.1 1.0e-12 0.25 0.88 0.01 TRUE
3 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma IL23R 0.06 0.03 blup 107 0.03 7.0e-03 10.3 14.8 2.5e-49 -0.13 0.15 0.10 TRUE
4 The Cancer Genome Atlas Rectum Adenocarcinoma IL23R 0.17 0.03 blup 108 0.15 2.3e-04 -6.2 14.0 8.5e-45 -0.11 0.08 0.05 TRUE
5 The Cancer Genome Atlas Testicular Germ Cell Tumors IL23R 0.25 0.07 lasso 8 0.05 1.0e-02 6.0 5.3 1.1e-07 -0.12 0.05 0.05 TRUE
6 The Cancer Genome Atlas Thyroid Carcinoma MIER1 0.19 0.05 blup 58 0.06 1.7e-06 4.1 5.9 3.5e-09 -0.25 0.79 0.08 TRUE