Hub : Genes

IL12RB2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1280 0.046 0.00230 0.005 0.019 0.071 0.058 0.030 7.2e-02 1.7e-03 5.2e-09 1.3e-07 1.2e-04
2 NTR Blood 0.0397 0.014 0.00033 0.023 0.022 0.020 0.024 0.018 4.9e-08 1.0e-07 3.8e-07 1.9e-08 1.4e-06

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 0.8 1.2 2.5 -0.0 -1.6
Bipolar Disorder or Schizophrenia 0.4 1.0 1.8 0.4 -1.3
Depressed Affect (Nagel 2018) 2.3 4.7 6.7 1.7 -2.6
Depression (Nagel 2018) 2.4 3.6 3.8 1.9 -1.9
Intelligence (Savage-Jansen 2018) 0.5 1.5 2.2 -1.5 -0.9
Neuroticism (Nagel 2018) 0.9 2.1 3.3 0.9 -1.8
Schizophrenia (2018) 0.1 0.2 0.2 0.5 -0.4
Schizophrenia vs Biploar Disorder 0.9 1.1 1.6 -1.3 -0.8
Worry (Nagel 2018) 0.6 1.3 2.6 0.2 -1.6
Alzheimer’s Disease (in mother) 1.4 1.7 3.2 0.3 -1.8
Alzheimer’s Disease (in father) 3.3 3.5 6.1 -1.0 -2.5
Alzheimer’s Disease (including proxy) 2.1 3.1 6.2 0.2 -2.5
Crohns Disease (2017) 6.0 13.2 19.8 2.6 -4.5
Irritable Bowel Disease (IBD) 9.8 23.4 37.0 3.1 -6.1
Ulcerative Colitis (UC) 7.3 13.8 23.6 2.0 -4.9
Major Depression (MDD) 0.5 0.7 0.8 0.9 -0.7
Reaction Time 0.3 0.5 0.7 -0.9 0.5
Verbal and Numeric Reasoning (VNR) 0.6 1.5 2.9 -1.7 0.3
Breast Cancer 1.3 3.2 4.5 -1.3 -2.1
Ovarian Cancer 3.4 4.5 5.4 1.9 -2.3
Prostate Cancer 2.3 3.2 5.7 -0.8 2.4
Age at First Birth 0.7 1.0 1.7 -1.3 -0.6
Bipolar Disorder (2011) 0.2 0.2 0.3 0.6 -0.3
Body Mass Index (BMI) (2010) 0.4 0.5 0.8 0.4 -0.9
Coronary Artery Disease (CAD) 0.1 0.1 0.2 -0.5 -0.0
Crohns Disease (2012) 8.3 13.4 21.6 2.3 -4.7
Mean Putamen Volume 1.0 1.1 2.0 -0.5 1.4
Fasting Glucose 0.0 0.0 0.0 -0.1 -0.2
HbA1C 0.4 0.5 1.0 0.0 -1.0
HDL Cholesterol 0.6 0.9 1.9 -0.0 -1.4
LDL Cholesterol 2.5 4.0 6.8 -1.1 2.6
Lupus 6.4 9.6 19.0 0.5 4.4
Neuroticism (2016) 1.1 1.6 1.7 -1.2 1.3
Primary Biliary Cirrhosis 37.2 53.1 89.3 -4.1 9.4
Rheumatoid Arthritis 2.6 3.6 5.8 -2.4 1.1
Schizophrenia (2014) 0.6 1.4 2.8 -0.1 -1.7
Triglycerides 0.3 0.5 0.9 -1.0 -0.2
Type 2 Diabetes (T2D) (2012) 0.6 0.7 1.0 -1.0 0.6
Ulcerative Colitis 7.2 10.5 16.4 2.1 -4.0
Blood Eosinophil Count 0.3 2.2 4.5 -0.2 -2.1
Blood Platelet Count 0.6 7.1 11.3 1.7 -3.4
Blood Red Count 0.1 0.6 1.0 -0.5 -1.0
Blood White Count 1.3 9.9 15.4 3.9 -2.1
Heel T-Score 1.0 8.0 15.8 -0.3 4.0
BMI 0.5 2.9 5.4 0.6 -2.3
Height 0.2 4.5 8.8 0.4 -3.0
Waist Hip Ratio (WHR) 0.2 1.1 2.2 0.3 -1.5
Systolic Blood Pressure 0.4 2.1 2.2 1.4 -1.5
Smoking Status 0.8 2.0 3.9 2.0 0.1
Allergy or Eczema 1.4 3.6 4.9 -2.2 1.5
Cardiovascular Disease 0.6 1.8 3.3 1.8 -0.6
Hypothyroidism (self reported) 5.7 13.0 14.7 -3.4 3.8
Respiratory disease 0.1 0.1 0.2 -0.2 -0.4
Type 2 Diabetes (T2D) (2018) 0.7 1.2 1.5 1.2 -1.0
Lung FEV1/FVC ratio 0.1 0.3 0.6 0.0 0.8
Lung FVC 0.1 0.4 0.4 -0.6 0.6
Neuroticism 0.3 0.8 1.1 0.8 -1.1
Chronotype (morning person) 3.2 7.5 14.1 -0.9 3.8
Hair Pigment 0.1 1.7 3.0 -1.7 0.7
Tanning 0.3 3.2 5.0 -1.2 2.2
Hand grip strength (left) 0.5 1.3 1.7 0.9 -1.3
Number of treatments/medications taken 0.0 0.0 0.1 0.2 -0.2
Average weekly spirits intake 1.7 2.1 4.1 -0.1 -2.0
Sensitivity / hurt feelings 0.0 0.0 0.1 0.2 0.0
Frequency of depressed mood in last 2 weeks 1.8 2.5 4.8 0.5 -2.2
Hearing difficulty/problems: Yes 0.3 0.5 0.7 0.8 0.5
Relative age of first facial hair 0.9 1.9 3.9 -0.0 -2.0
Other serious medical condition/disability diagnosed by doctor 0.1 0.1 0.1 -0.4 0.0
Ever used hormone-replacement therapy (HRT) 0.4 0.5 0.7 0.5 -0.8
Ever had hysterectomy (womb removed) 0.7 0.8 0.9 1.0 -0.8
Systolic blood pressure, automated reading 1.1 3.1 5.4 0.9 -2.3
Eye problems/disorders: Diabetes related eye disease 0.8 0.9 1.1 1.0 -0.9
Angina 1.1 1.5 1.7 -1.1 1.3
Medication for hormone replacement therapy 1.2 1.4 2.1 -1.4 -0.8
Vitamin and mineral supplements 0.6 0.8 0.8 0.8 -0.9
Supplements: Zinc 2.4 2.6 5.1 2.3 -0.1
Medication: Co-codamol 0.6 0.7 1.3 -0.4 1.1
Medication: Metformin 0.7 1.0 1.8 1.3 -0.4
Diabetes (father) 0.5 0.7 1.0 0.6 -1.0
Diabetes (mother) 2.9 3.7 4.2 -1.8 -2.0
Severe depression (siblings) 1.4 1.6 2.8 1.7 -0.6
Pack years adult smoking proportion 1.0 1.6 2.9 0.5 -1.7
Impedance of leg (right) 0.6 2.7 5.4 2.3 0.3
Leg fat-free mass (left) 0.9 4.9 8.8 -1.0 -3.0
Trunk fat percentage 0.8 3.1 5.1 2.3 -1.1
Hand grip strength (right) 0.2 0.6 1.2 -0.1 -1.1
Townsend deprivation index at recruitment 0.0 0.0 0.0 0.2 0.2
Current tobacco smoking 0.0 0.0 0.1 -0.0 0.3
Average weekly fortified wine intake 1.7 2.0 3.8 -1.9 0.5
Maternal smoking around birth 0.6 0.9 1.8 -1.3 -0.2
Fed-up feelings 0.5 0.9 1.6 -0.4 -1.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.1 1.8 0.6 -1.3
Relative age voice broke 0.9 1.4 2.8 -0.2 -1.7
Taking other prescription medications 0.4 0.6 1.2 -1.1 0.3
Age when periods started (menarche) 0.4 0.9 1.1 -0.8 -1.1
Bilateral oophorectomy (both ovaries removed) 0.2 0.2 0.4 -0.2 0.7
Heel bone mineral density (BMD) T-score, automated (left) 2.0 4.6 6.8 -1.6 2.6
Tinnitus: Yes, but not now, but have in the past 2.2 2.3 3.6 1.0 1.9
Qualifications: CSEs or equivalent 0.1 0.1 0.2 -0.3 0.4
Serious illness, injury or assault to yourself 0.8 0.9 1.2 0.8 -1.1
High blood pressure 0.6 1.6 2.6 1.6 -0.8
Hayfever, allergic rhinitis or eczema 1.8 3.9 4.2 -1.9 2.1
Multivitamins +/- minerals 0.4 0.5 0.7 -0.4 0.9
Stomach or abdominal pain in last month 3.4 4.3 6.5 2.6 -1.4
Supplements: Glucosamine 1.4 1.8 2.3 1.1 -1.5
Diverticular disease/diverticulitis (self-reported) 0.1 0.1 0.2 0.4 0.3
Medication: Atenolol 0.2 0.2 0.3 -0.6 -0.4
Medication: Levothyroxine sodium 1.5 2.5 4.5 -0.8 2.1
Sitting height 0.3 2.4 4.5 -0.6 -2.1
Chronic bronchitis/emphysema (father) 0.1 0.1 0.1 -0.3 0.1
High blood pressure (mother) 1.1 1.6 1.7 1.2 1.3
Body mass index (BMI) 0.6 2.7 5.3 0.4 -2.3
Impedance of leg (left) 0.7 3.5 5.4 2.3 1.2
Leg predicted mass (left) 0.9 4.7 8.3 -1.0 -2.9
Trunk fat mass 0.8 3.4 3.9 1.7 -2.0
Waist circumference 1.1 4.2 7.9 0.6 -2.8
Number of incorrect matches in round 0.6 1.0 1.2 1.0 1.1
Past tobacco smoking 0.8 1.5 2.9 -1.7 -0.5
Alcohol usually taken with meals 4.7 7.6 7.7 -2.7 2.8
Nervous feelings 0.7 1.3 2.4 0.4 -1.5
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.7 1.3 -1.2 0.2
Hearing difficulty/problems with background noise 0.7 1.2 2.0 0.6 1.4
Hair/balding pattern: Pattern 2 0.1 0.1 0.2 0.3 0.4
Had menopause 0.2 0.2 0.4 -0.6 -0.3
Had other major operations 1.1 1.3 2.4 -1.5 -0.5
Forced vital capacity (FVC) 0.1 0.2 0.3 -0.5 -0.4
Heel bone mineral density (BMD) T-score, automated (right) 2.4 5.5 6.7 -2.0 2.6
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 1.0 0.1 -1.0
Qualifications: None of the above 0.7 1.5 1.7 1.1 -1.3
Financial difficulties in last 2 years 0.6 0.8 1.2 1.1 -0.7
Mouth/teeth dental problems 1.5 2.3 4.6 0.1 2.1
Heart attack 0.6 0.8 1.0 -0.8 1.0
Allergy 0.6 1.3 1.8 1.3 -1.0
Pain all over the body in last month 0.5 0.6 0.9 -1.0 -0.5
Diabetes (self-reported) 0.3 0.5 0.9 1.0 -0.1
Hayfever/allergic rhinitis (self-reported) 0.4 0.6 0.8 -0.9 -0.6
Medication: Ramipril 0.1 0.1 0.2 0.1 -0.5
Medication: Simvastatin 2.5 3.7 5.3 2.3 -1.4
Fluid intelligence score 0.8 1.7 1.8 -1.2 -1.3
Illnesses of siblings 0.5 0.7 1.3 -1.1 0.4
Neuroticism score 0.3 0.6 1.0 0.4 -1.0
Weight 1.0 5.0 9.8 0.3 -3.1
Impedance of arm (right) 0.7 3.4 3.6 1.8 1.9
Arm fat percentage (right) 0.4 1.5 1.7 1.3 -1.2
Trunk fat-free mass 1.4 7.9 13.9 -1.4 -3.7
Hip circumference 1.0 4.3 8.1 0.8 -2.8
Time employed in main current job 0.1 0.1 0.1 -0.1 0.4
Alcohol intake versus 10 years previously 0.4 0.6 0.9 0.5 -0.9
Father’s age at death 1.2 1.6 3.1 0.3 1.8
Worrier / anxious feelings 0.7 1.4 2.3 0.7 -1.5
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.3 0.5 -0.0 -0.7
Falls in the last year 0.0 0.0 0.1 0.2 -0.2
Hair/balding pattern: Pattern 3 0.1 0.2 0.3 0.6 0.1
Number of live births 0.2 0.3 0.6 -0.8 0.1
Forced expiratory volume in 1-second (FEV1) 0.1 0.4 0.8 -0.9 -0.3
Pulse rate 0.0 0.0 0.0 0.2 -0.1
Happiness 0.6 0.7 1.1 1.0 -0.6
Noisy workplace 0.3 0.3 0.6 0.3 0.7
Qualifications: A levels/AS levels or equivalent 0.9 2.0 4.0 -2.0 -0.2
Serious illness, injury or assault of a close relative in last 2 years 2.3 2.7 5.4 -0.1 -2.3
Mouth/teeth dental problems: Dentures 1.2 2.1 4.2 0.0 -2.0
Asthma 0.3 0.6 0.9 -0.9 0.5
Medication: Ibuprofen (e.g. Nurofen) 0.0 0.0 0.0 -0.1 0.0
Medication: Cholesterol lowering 3.2 5.0 9.6 3.1 0.6
Depression (self-reported) 0.3 0.4 0.7 0.9 0.2
Medication: Lansoprazole 1.5 1.7 2.1 1.1 -1.4
Prospective memory result 0.1 0.1 0.3 -0.1 0.5
Lung cancer (father) 0.1 0.2 0.2 0.4 -0.4
Illnesses of mother 0.2 0.3 0.4 0.4 0.6
Forced expiratory volume in 1-second (FEV1), Best measure 0.0 0.1 0.1 -0.2 -0.4
Pulse wave Arterial Stiffness index 3.7 4.3 5.9 2.4 -1.6
Impedance of arm (left) 1.3 5.9 8.8 1.8 3.0
Arm fat mass (right) 0.7 2.7 4.3 1.0 -2.1
Trunk predicted mass 1.4 8.0 14.1 -1.4 -3.8
Standing height 0.2 2.2 4.3 -0.1 -2.1
Length of working week for main job 0.2 0.2 0.3 0.1 0.6
Exposure to tobacco smoke at home 0.0 0.0 0.1 -0.0 0.3
Breastfed as a baby 0.4 0.5 0.6 0.8 0.6
Tense / ‘highly strung’ 0.7 1.2 2.3 -0.4 -1.5
Seen doctor (GP) for nerves, anxiety, tension or depression 0.0 0.1 0.1 0.2 -0.3
Hair/balding pattern: Pattern 4 0.9 2.1 2.6 1.6 -1.3
Birth weight of first child 0.8 1.4 1.7 1.0 -1.3
Peak expiratory flow (PEF) 0.0 0.1 0.2 -0.1 0.4
Pulse wave reflection index 0.3 0.4 0.4 0.6 -0.6
Ever highly irritable/argumentative for 2 days 0.2 0.2 0.4 0.6 -0.3
Loud music exposure frequency 0.2 0.3 0.4 0.3 -0.6
Qualifications: O levels/GCSEs or equivalent 1.9 3.1 4.6 -1.3 2.1
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 0.6 -0.8 -0.4
Blood clot in the leg (DVT) 1.4 1.8 3.4 0.4 -1.9
Medication: Paracetamol 0.2 0.3 0.3 0.6 -0.4
Headache pain in last month 0.4 0.7 1.3 1.1 -0.2
Medication for cholesterol, blood pressure or diabetes 4.5 7.4 14.6 -3.8 0.4
Glaucoma (self-reported) 0.5 0.6 1.0 -0.5 -1.0
Gout (self-reported) 3.5 4.8 5.4 2.3 -2.0
Hypothyroidism/myxoedema (self-reported) 2.4 4.7 4.8 -2.2 2.2
Medication: Amlodipine 1.1 1.5 2.6 1.6 0.6
Medication: Ventolin 100micrograms inhaler 0.5 0.7 1.1 -0.5 1.0
Birth weight 0.1 0.2 0.2 0.4 0.5
Chronic bronchitis/emphysema (mother) 3.3 3.9 7.6 0.3 -2.8
High blood pressure (siblings) 0.2 0.3 0.6 0.8 -0.4
Forced vital capacity (FVC), Best measure 0.0 0.2 0.3 0.0 -0.6
Body fat percentage 0.9 3.5 4.8 2.2 -1.5
Leg fat percentage (right) 1.1 4.1 5.8 1.6 -2.4
Arm fat-free mass (right) 1.1 5.9 11.4 -0.7 -3.4
Exposure to tobacco smoke outside home 2.3 3.0 4.4 2.1 -1.3
Comparative body size at age 10 0.0 0.1 0.1 -0.3 -0.2
Number of full brothers 0.0 0.0 0.0 0.0 0.0
Worry too long after embarrassment 0.1 0.1 0.2 -0.3 0.4
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.3 0.6 -0.0 0.8
Wheeze or whistling in the chest in last year 0.1 0.2 0.3 0.4 -0.5
Number of children fathered 0.2 0.2 0.5 -0.2 0.7
Reason for reducing amount of alcohol drunk: Health precaution 0.5 0.5 0.9 1.0 0.4
Age at first live birth 0.1 0.1 0.1 -0.3 0.3
Pulse wave peak to peak time 3.4 4.0 6.5 -2.5 1.2
Health satisfaction 0.3 0.3 0.6 0.8 -0.2
Shortness of breath walking on level ground 0.9 1.1 1.7 0.7 -1.3
Qualifications: College or University degree 0.4 1.3 1.5 -1.2 -1.1
Eye problems/disorders: None of the above 0.3 0.3 0.4 -0.6 0.5
Mouth/teeth dental problems: Loose teeth 0.6 0.7 1.1 -0.6 -1.0
Emphysema/chronic bronchitis 2.7 3.0 3.5 1.6 -1.9
Medication for pain relief, constipation, heartburn 0.1 0.2 0.4 -0.6 -0.2
Neck or shoulder pain in last month 0.5 0.8 1.5 -0.1 -1.2
Medication: Blood pressure 3.5 6.3 12.0 3.5 -0.8
Angina (self-reported) 0.8 1.1 1.1 -1.0 1.0
Migraine (self-reported) 2.5 3.1 5.9 2.4 -0.5
Medication: Ibuprofen 0.2 0.2 0.4 0.2 -0.6
Medication: Allopurinol 3.5 4.7 6.8 1.6 -2.6
Medication: Omeprazole 0.9 1.0 1.8 -0.5 1.4
Medication: Seretide 50 evohaler 0.2 0.2 0.4 -0.7 0.2
Mean time to correctly identify matches 0.4 0.7 1.4 -0.2 1.2
Heart disease (mother) 1.2 1.5 2.5 -1.6 0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.3 1.6 2.4 -1.6 0.8
Whole body fat mass 0.9 3.7 4.7 1.6 -2.2
Leg fat mass (right) 1.1 4.3 7.1 1.2 -2.7
Arm predicted mass (right) 1.2 6.1 11.6 -0.8 -3.4
Pulse rate, automated reading 0.3 0.9 1.8 1.4 -0.1
Alcohol intake frequency. 0.1 0.3 0.5 0.7 -0.3
Comparative height size at age 10 0.2 1.0 1.6 -0.6 -1.3
Number of full sisters 0.1 0.1 0.1 0.2 0.4
Suffer from ‘nerves’ 1.3 2.1 3.9 -2.0 -0.5
Overall health rating 0.5 1.1 2.0 0.4 -1.4
Chest pain or discomfort 0.5 0.7 0.7 0.8 -0.8
Had major operations 1.1 1.3 2.6 0.2 -1.6
Age at last live birth 0.2 0.3 0.6 -0.8 0.2
Family relationship satisfaction 0.9 1.1 1.3 0.9 -1.2
Leg pain on walking 1.3 1.7 1.8 1.2 -1.3
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.3 0.6 -0.2 0.8
Commuting to job workplace: Car/motor vehicle 0.3 0.4 0.5 0.5 0.7
Illness, injury, bereavement, stress in last 2 years 0.7 0.8 1.1 -1.1 0.7
Medication: Aspirin 0.2 0.2 0.4 0.7 -0.0
Supplements: Vitamin C 2.9 3.5 4.4 -1.6 2.1
Knee pain experienced in last month 0.1 0.1 0.2 0.4 0.3
Hypertension (Self-reported) 0.5 1.4 2.5 1.6 -0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 1.0 -1.0 0.4
Illnesses of father: Heart disease 0.3 0.4 0.4 -0.7 0.5
Illnesses of siblings: Diabetes 0.4 0.4 0.5 -0.7 -0.6
Smoking status: Previous 0.9 1.4 2.8 1.7 0.0
Forced expiratory volume in 1-second (FEV1), predicted 0.2 0.3 0.6 0.3 -0.7
Whole body fat-free mass 1.2 7.1 12.6 -1.3 -3.5
Leg fat-free mass (right) 0.7 3.6 5.8 -1.2 -2.4
Arm fat percentage (left) 0.2 0.8 1.1 1.1 -0.7
Average weekly red wine intake 1.7 2.5 3.6 -1.2 1.9
Handedness (chirality/laterality): Left-handed 0.2 0.3 0.3 0.5 -0.5
Mood swings 2.5 4.6 4.8 2.2 -2.1
Loneliness, isolation 0.7 1.0 2.0 0.2 -1.4
Long-standing illness, disability or infirmity 0.4 0.6 0.7 0.9 0.6
Ever had bowel cancer screening 0.3 0.4 0.4 0.6 0.6
Diabetes diagnosed by doctor 0.2 0.3 0.5 0.7 -0.2
Ever had stillbirth, spontaneous miscarriage or termination 0.9 1.0 1.8 -1.3 -0.5
Friendships satisfaction 1.1 1.4 2.8 -1.7 -0.1
Qualifications: nursing, teaching 0.9 1.3 2.2 -1.5 0.7
Commuting to job workplace: Walk 0.6 0.7 1.3 1.1 -0.3
Eye problems/disorders: Cataract 0.7 0.8 0.9 0.9 -0.9
Mouth/teeth dental problems: Mouth ulcers 7.5 12.0 13.7 3.2 -3.7
Medication for cholesterol 0.1 0.1 0.3 0.5 0.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.4 0.7 0.5 -0.8
Back pain experienced in last month 0.1 0.1 0.2 -0.0 -0.5
Mineral and other dietary supplements 0.2 0.3 0.5 0.3 0.7
Breast cancer (self-reported) 0.1 0.1 0.2 0.4 0.0
Asthma (self-reported) 0.4 0.7 0.8 -0.9 0.8
Osteoporosis (self-reported) 0.1 0.1 0.1 -0.4 -0.1
Osteoarthritis (self-reported) 0.6 0.8 1.2 0.5 -1.1
Medication: Aspirin 0.2 0.3 0.3 0.5 -0.6
Medication: Gliclazide 0.4 0.4 0.5 -0.7 -0.6
Illnesses of father: None of the above (group 1) 0.3 0.3 0.6 0.0 0.8
Smoking status: Current 0.1 0.1 0.2 0.1 0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.0 0.1 0.1 0.3 0.1
Whole body water mass 1.1 6.3 11.2 -1.2 -3.4
Leg predicted mass (right) 0.7 3.7 5.9 -1.2 -2.4
Arm fat mass (left) 0.4 1.8 2.8 0.8 -1.7
Number of self-reported non-cancer illnesses 0.9 1.5 1.8 1.4 -1.1
Average weekly champagne plus white wine intake 0.1 0.2 0.4 -0.6 0.1
Miserableness 2.2 3.8 5.2 1.5 -2.3
Guilty feelings 0.7 1.1 2.0 -0.3 1.4
Wears glasses or contact lenses 0.2 0.2 0.3 0.5 -0.3
Ever taken oral contraceptive pill 0.4 0.5 0.9 0.9 -0.3
Hearing aid user 1.1 1.2 1.2 1.1 1.1
Mother’s age at death 0.2 0.3 0.3 -0.6 -0.6
Financial situation satisfaction 0.2 0.3 0.5 0.7 0.2
Tinnitus: Yes, now most or all of the time 0.6 0.7 1.3 -1.1 -0.5
Commuting to job workplace: Public transport 0.1 0.1 0.2 0.2 -0.5
Eye problems/disorders: Glaucoma 0.1 0.1 0.1 -0.3 -0.3
Medication: Blood pressure 0.3 0.5 0.8 -0.9 0.5
Pain type(s) experienced in last month: Hip pain 0.4 0.5 0.9 0.3 -0.9
Supplements: Fish oil (including cod liver oil) 0.0 0.0 0.0 -0.1 0.1
High cholesterol (Self-reported) 1.6 2.8 5.7 2.4 -0.1
Medication: Bendroflumethiazide 1.1 1.7 2.3 1.5 -1.0
Medication: Paracetamol 0.6 1.0 1.8 0.5 -1.3
Medication: Lisinopril 0.6 0.8 1.3 0.6 1.1
Medication: Atorvastatin 3.0 3.7 6.7 0.9 2.6
Illnesses of father: High blood pressure 0.1 0.1 0.1 -0.4 -0.3
Alcohol drinker status: Never 0.3 0.3 0.6 -0.1 0.8
Ever smoked 0.2 0.4 0.7 0.8 -0.3
Basal metabolic rate 1.2 6.5 12.4 -0.7 -3.5
Leg fat percentage (left) 1.0 3.4 3.5 1.9 -1.8
Arm fat-free mass (left) 1.3 6.6 13.0 -0.4 -3.6
Number of operations (self-reported) 0.6 0.9 1.8 -0.3 -1.3
Average weekly beer plus cider intake 1.0 1.5 2.7 1.6 -0.5
Irritability 0.6 1.0 1.7 -0.6 -1.3
Risk taking 2.1 3.1 4.3 -2.1 1.4
Ever had prostate specific antigen (PSA) test 2.0 2.3 4.5 -0.4 2.1
Fractured/broken bones in last 5 years 0.8 1.1 1.2 1.0 -1.1
Age started oral contraceptive pill 0.1 0.2 0.2 0.4 -0.4
Diastolic blood pressure, automated reading 1.4 4.4 7.7 1.1 -2.8
Ever depressed for a whole week 1.4 1.7 2.4 1.5 -1.0
Unable to work because of sickness or disability 0.3 0.4 0.7 0.8 -0.5
Commuting to job workplace: Cycle 1.5 1.8 2.5 -1.1 1.6
Myopia 0.5 0.7 0.9 -0.7 0.9
Vascular/heart problems diagnosed by doctor 0.4 1.0 1.2 -0.9 1.1
Cholesterol lowering medication 0.3 0.4 0.8 -0.9 -0.2
Medication: Omeprazole (e.g. Zanprol) 1.3 1.6 2.7 -0.7 1.7
Pain experienced in last month 0.0 0.0 0.1 0.0 -0.2
Supplements: Calcium 1.0 1.1 2.0 1.4 -0.5
Basal cell carcinoma (self-reported) 2.7 3.2 4.5 -2.1 1.4
Heart attack/myocardial infarction (self-reported) 0.5 0.6 0.7 -0.9 0.7
Deep venous thrombosis (DVT) (self-reported) 1.1 1.4 2.6 0.5 -1.6
Heart disease (siblings) 0.3 0.3 0.6 0.1 0.8
Alcohol drinker status: Previous 0.7 0.8 1.1 1.1 -0.6
Pack years of smoking 0.9 1.4 2.5 0.5 -1.6
Impedance of whole body 0.9 4.8 4.8 2.2 2.2
Leg fat mass (left) 1.1 4.2 6.0 1.5 -2.5
Arm predicted mass (left) 1.3 6.4 12.7 -0.3 -3.6