[Hub]/) : Traits : Irritable Bowel Disease (IBD) : ← →

chr17:39,328,012-41,699,963

Best TWAS P=6.92e-16 · Best GWAS P=1.34e-18 conditioned to 0.366

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	NAGLU	0.04	0.03	bslmm	246	0.01	6.5e-02	-5.6	7.2	8.1e-13	-0.32	0.07	0.03	FALSE
2	GTEx	Adipose Subcutaneous	NAGLU	0.31	0.12	lasso	3	0.11	3.7e-09	-5.6	5.8	6.2e-09	-0.39	1.00	0.00	FALSE
3	GTEx	Adipose Subcutaneous	RP11-400F19.8	0.13	0.08	lasso	2	0.07	1.7e-06	-5.6	5.6	1.7e-08	-0.39	0.90	0.00	FALSE
4	GTEx	Artery Aorta	NAGLU	0.22	0.10	enet	23	0.11	1.1e-06	-5.7	6.3	2.8e-10	-0.47	0.86	0.01	FALSE
5	GTEx	Artery Aorta	RP11-400F19.8	0.21	0.08	enet	19	0.07	7.0e-05	-5.7	6.1	1.1e-09	-0.46	0.48	0.03	FALSE
6	GTEx	Artery Tibial	NAGLU	0.18	0.12	lasso	4	0.13	3.3e-10	-5.6	5.6	1.9e-08	-0.37	1.00	0.00	FALSE
7	GTEx	Artery Tibial	RP11-400F19.8	0.16	0.11	lasso	5	0.11	8.1e-09	-5.6	5.7	1.6e-08	-0.38	0.99	0.00	FALSE
8	GTEx	Brain Caudate basal ganglia	NAGLU	0.15	0.19	lasso	2	0.15	5.0e-05	-5.6	5.6	2.6e-08	-0.39	0.17	0.10	FALSE
9	GTEx	Breast Mammary Tissue (Male)	HSD17B1P1	0.09	0.14	lasso	1	0.07	1.2e-02	5.6	-5.6	2.2e-08	0.18	0.03	0.06	TRUE
10	GTEx	Cells Transformed fibroblasts	NAGLU	0.28	0.22	lasso	4	0.22	7.5e-17	-5.6	5.6	1.9e-08	-0.41	1.00	0.00	FALSE
11	GTEx	Cells Transformed fibroblasts	RP11-400F19.8	0.20	0.16	lasso	3	0.15	1.4e-11	-5.6	5.5	4.2e-08	-0.39	1.00	0.00	FALSE
12	GTEx	Colon Sigmoid	AOC3	0.26	0.03	lasso	11	0.02	5.5e-02	-3.1	6.0	2.2e-09	-0.45	0.04	0.32	FALSE
13	GTEx	Esophagus Muscularis	NAGLU	0.29	0.09	lasso	5	0.07	6.2e-05	-5.7	5.4	7.4e-08	-0.44	0.73	0.01	FALSE
14	GTEx	Muscle Skeletal	TUBG2	0.12	0.09	lasso	8	0.10	1.1e-09	-3.8	5.5	5.0e-08	-0.46	0.99	0.00	FALSE
15	GTEx	Muscle Skeletal	HSD17B1P1	0.05	0.03	lasso	3	0.02	2.0e-03	5.7	-5.5	5.2e-08	0.17	0.28	0.03	FALSE
16	GTEx	Nerve Tibial	NAGLU	0.15	0.10	lasso	4	0.08	2.3e-06	-5.6	5.8	7.6e-09	-0.42	0.98	0.00	FALSE
17	GTEx	Nerve Tibial	RP11-400F19.8	0.10	0.03	lasso	3	0.02	8.2e-03	-5.7	5.7	9.8e-09	-0.50	0.19	0.03	FALSE
18	GTEx	Spleen	CTD-3193K9.3	0.16	0.10	enet	24	0.14	1.6e-04	2.6	6.7	2.6e-11	-0.33	0.20	0.06	FALSE
19	GTEx	Thyroid	STAT5A	0.09	0.03	lasso	4	0.04	3.4e-04	-6.9	5.4	6.5e-08	-0.27	0.26	0.38	TRUE
20	GTEx	Vagina	ACLY	0.48	0.08	enet	71	0.22	7.5e-06	-6.8	-5.4	5.3e-08	0.52	0.16	0.18	FALSE
21	GTEx	Whole Blood	HSD17B1P1	0.04	0.02	enet	16	0.03	1.0e-03	4.8	-5.4	8.4e-08	0.19	0.18	0.03	FALSE
22	METSIM	Adipose	NAGLU	0.05	0.05	lasso	4	0.05	4.5e-08	-5.6	5.6	2.0e-08	-0.36	0.99	0.00	FALSE
23	METSIM	Adipose	PTRF	0.03	0.02	lasso	3	0.01	3.3e-03	-8.2	8.1	6.9e-16	-0.83	0.02	0.98	TRUE
24	NTR	Blood	FAM134C	0.01	0.00	bslmm	265	0.00	8.2e-03	-8.1	7.2	4.1e-13	-0.59	0.04	0.23	FALSE
25	YFS	Blood	FAM134C	0.03	0.01	enet	12	0.01	1.2e-05	-3.1	7.3	2.4e-13	-0.30	0.34	0.03	FALSE
26	YFS	Blood	NAGLU	0.04	0.02	lasso	4	0.03	1.3e-09	-5.6	5.8	7.1e-09	-0.37	1.00	0.00	FALSE
27	The Cancer Genome Atlas	Breast Invasive Carcinoma	NAGLU	0.19	0.03	lasso	1	0.03	9.1e-07	-5.6	5.6	1.7e-08	-0.39	0.00	1.00	FALSE
28	The Cancer Genome Atlas	Rectum Adenocarcinoma	NAGLU	0.35	0.01	enet	14	0.13	7.2e-04	-5.6	5.3	1.2e-07	-0.20	0.00	0.73	FALSE
29	The Cancer Genome Atlas	Thyroid Carcinoma	NAGLU	0.59	0.09	lasso	2	0.09	6.2e-09	-5.6	5.6	1.7e-08	-0.39	0.00	1.00	FALSE