Best TWAS P=4.6e-08 · Best GWAS P=2.16e-07 conditioned to 0.646
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | ITPKC | 0.12 | 0.07 | enet | 13 | 0.05 | 8.1e-04 | 5.2 | 5.5 | 4.6e-08 | 0.91 | 0.00 | 0.99 | TRUE |
| 2 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | ADCK4 | 0.20 | 0.16 | enet | 8 | 0.14 | 2.7e-06 | 5.1 | -5.2 | 2.6e-07 | -0.88 | 0.01 | 0.98 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ITPKC | 0.11 | 0.11 | lasso | 5 | 0.09 | 2.1e-09 | -4.9 | 5.1 | 2.9e-07 | 0.93 | 0.01 | 0.99 | FALSE |