TWAS hub - ITPKC

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.1240	0.0430	1.3e-03	0.066	NA	0.055	NA	0.015	2.6e-04	NA	8.1e-04	NA	5.2e-02
2	GTEx	Cells Transformed fibroblasts	0.1290	0.0460	1.4e-03	0.023	NA	0.059	NA	0.059	6.7e-03	NA	3.4e-05	NA	3.0e-05
3	GTEx	Esophagus Mucosa	0.0930	0.0360	2.6e-03	0.059	NA	0.028	NA	0.045	9.0e-05	NA	5.1e-03	NA	5.3e-04
4	GTEx	Liver	0.3360	0.1070	2.5e-03	-0.010	NA	0.025	NA	-0.009	7.8e-01	NA	6.6e-02	NA	7.1e-01
5	GTEx	Muscle Skeletal	0.0992	0.0285	1.5e-05	0.074	NA	0.055	NA	0.053	9.2e-08	NA	4.2e-06	NA	5.6e-06
6	GTEx	Nerve Tibial	0.1061	0.0428	4.1e-03	0.075	NA	0.067	NA	0.066	5.6e-06	NA	1.7e-05	NA	2.0e-05
7	GTEx	Skin Sun Exposed Lower leg	0.0740	0.0300	5.8e-03	0.066	NA	0.074	NA	0.074	3.8e-06	NA	1.0e-06	NA	1.1e-06
8	NTR	Blood	0.0121	0.0065	3.0e-02	0.000	0.000	0.001	0	0.000	4.3e-01	3.9e-01	1.8e-01	0.25	4.1e-01
9	TCGA	Breast Invasive Carcinoma	0.0629	0.0242	6.8e-08	0.017	0.032	0.047	NA	0.010	1.3e-04	2.5e-07	4.7e-10	NA	3.3e-03
10	TCGA	Cervical Squamous Cell Carcinoma	0.1450	0.0680	1.5e-03	0.065	0.029	0.046	NA	0.040	4.0e-04	1.5e-02	2.6e-03	NA	4.5e-03
11	TCGA	Colon Adenocarcinoma	0.0750	0.0390	3.6e-03	0.028	0.018	0.007	NA	0.019	9.7e-03	2.9e-02	1.2e-01	NA	2.7e-02
12	TCGA	Glioblastoma Multiforme	0.1130	0.0610	6.5e-03	-0.002	0.045	0.014	NA	0.005	3.7e-01	1.7e-02	1.2e-01	NA	2.1e-01
13	TCGA	Head and Neck Squamous Cell Carcinoma	0.0879	0.0502	6.0e-04	0.009	0.020	0.054	NA	0.033	2.7e-02	2.3e-03	9.9e-07	NA	1.2e-04
14	TCGA	Kidney Renal Clear Cell Carcinoma	0.0291	0.0173	5.1e-03	0.004	0.016	0.012	NA	0.006	1.0e-01	6.1e-03	1.6e-02	NA	6.3e-02
15	TCGA	Lung Adenocarcinoma	0.0422	0.0208	4.9e-04	0.001	0.016	0.014	NA	0.008	2.3e-01	4.7e-03	7.0e-03	NA	3.5e-02
16	TCGA	Lung Squamous Cell Carcinoma	0.0340	0.0197	2.9e-03	0.016	0.018	0.017	NA	0.013	6.0e-03	3.4e-03	4.5e-03	NA	1.1e-02
17	TCGA	Prostate Adenocarcinoma	0.1087	0.0421	6.0e-10	0.113	0.080	0.078	NA	0.087	7.0e-12	1.1e-08	1.5e-08	NA	2.1e-09
18	TCGA	Stomach Adenocarcinoma	0.0840	0.0570	5.7e-03	0.028	0.018	0.007	NA	0.014	3.8e-03	1.8e-02	8.8e-02	NA	3.4e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	9	10	11	12	13	14	15	16	17	18
Irritable Bowel Disease (IBD)	7.3	17.5	29.9	5.5	4.4	4.2	-0.3	4.9	4.8	4.9	4.0	4.6	2.9	4.2	3.4	4.7	3.7	4.8	5.1	4.0
Crohns Disease (2017)	6.8	14.9	23.9	4.3	4.3	4.1	0.0	4.5	4.4	4.5	3.7	4.5	3.1	3.9	3.5	4.4	3.7	4.1	4.9	3.2
Pain experienced in last month	4.5	7.5	15.5	3.9	2.5	3.3	1.6	3.6	2.9	3.6	1.2	2.3	1.1	3.9	1.0	3.3	2.7	3.2	3.2	1.6
Current tobacco smoking	4.4	7.3	14.3	3.7	2.2	2.5	2.8	2.0	3.6	3.4	1.1	2.2	0.7	3.8	2.2	2.8	3.3	2.7	3.4	2.3
Medication: Seretide 50 evohaler	4.4	5.0	8.8	-2.7	-2.4	-2.5	-0.4	-2.3	-2.3	-2.7	-3.0	-2.7	-1.4	-2.2	-2.5	-2.5	-1.9	-1.9	-2.9	-1.3
HDL Cholesterol	4.0	6.7	11.5	-2.6	-2.9	-2.9	0.6	-2.1	-2.1	-2.8	-1.8	-2.9	-2.5	-3.1	-2.3	-3.0	-3.4	-3.3	-2.7	-2.9
Ulcerative Colitis (UC)	3.9	7.3	15.8	4.0	2.7	2.6	-0.1	3.0	3.3	3.2	2.6	2.9	1.6	2.6	2.0	3.0	2.2	3.2	3.2	3.0
Medication: Paracetamol	3.1	5.1	8.2	-2.3	-2.3	-2.6	-1.4	-2.5	-2.9	-2.3	-1.0	-2.3	-2.4	-2.6	-2.2	-2.4	-2.9	-2.3	-2.6	-1.4
Mouth/teeth dental problems: Mouth ulcers	3.1	4.9	12.4	2.4	2.6	3.5	0.5	1.6	2.9	2.4	2.0	3.1	1.1	2.0	2.1	2.0	2.3	2.2	2.7	1.6
Ulcerative Colitis	3.0	4.3	9.4	3.1	1.9	1.9	-0.1	2.0	2.4	2.7	1.8	2.1	0.5	2.2	0.7	2.3	1.4	2.7	2.6	2.9
Respiratory disease	3.0	6.7	14.3	-3.6	-1.9	-2.9	-0.3	-3.2	-3.7	-3.6	-1.0	-2.2	-1.1	-3.8	-1.1	-3.0	-2.7	-2.2	-3.3	-1.6
Wears glasses or contact lenses	3.0	3.4	5.5	-2.3	-2.1	-2.2	-2.0	-1.9	-2.0	-2.1	-1.6	-2.1	-1.5	-1.9	-1.7	-2.0	-1.7	-1.6	-2.2	-1.0
Smoking status: Current	2.9	4.6	9.0	3.0	1.7	2.1	2.5	1.7	3.0	2.7	0.7	1.7	0.3	3.0	1.8	2.2	2.6	2.0	2.7	1.9
Lung FEV1/FVC ratio	2.8	14.3	40.1	5.8	2.9	4.0	0.3	6.3	4.4	4.8	2.3	3.5	0.6	4.4	2.8	3.8	3.0	4.3	4.6	2.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.8	3.3	9.4	-1.5	-1.9	-1.7	0.1	-1.7	-2.0	-1.9	-0.4	-1.5	-2.2	-2.8	-1.0	-2.1	-3.1	-2.0	-2.0	-1.3
Illnesses of siblings: Diabetes	2.6	3.1	6.9	1.1	2.6	1.7	0.4	1.6	2.0	2.1	1.6	1.8	2.6	2.3	0.9	2.4	2.2	1.1	2.0	0.4
Supplements: Glucosamine	2.5	3.3	5.4	-1.2	-2.1	-1.6	-1.2	-0.9	-1.6	-1.9	-2.3	-2.1	-2.0	-2.2	-1.8	-2.2	-2.3	-1.8	-2.2	-1.6
Asthma	2.5	4.9	11.2	-2.9	-1.8	-2.8	-0.2	-2.7	-3.4	-3.2	-1.0	-2.1	-1.1	-3.1	-0.8	-2.6	-2.3	-1.3	-3.1	-0.7
Asthma (self-reported)	2.5	5.0	11.8	-2.9	-1.8	-2.8	-0.3	-2.7	-3.4	-3.2	-1.0	-2.1	-0.9	-3.1	-0.9	-2.6	-2.2	-1.5	-3.1	-1.0
Medication: Paracetamol	2.5	3.9	7.2	-2.0	-2.0	-2.3	-0.4	-2.1	-2.7	-1.9	-0.9	-1.9	-1.8	-2.3	-2.3	-2.1	-2.4	-2.3	-2.2	-1.5
Ever had prostate specific antigen (PSA) test	2.5	2.8	6.1	2.4	1.6	1.4	1.2	1.8	1.1	1.8	1.9	1.6	1.0	2.1	0.6	1.9	1.8	2.5	1.7	1.9
Supplements: Zinc	2.4	2.6	8.2	2.2	1.5	0.9	1.7	2.9	2.0	1.8	0.9	1.1	1.5	1.8	1.3	1.9	1.4	1.6	1.7	0.7
Medication: Ibuprofen (e.g. Nurofen)	2.4	3.0	6.2	-2.2	-1.6	-2.2	-1.0	-1.9	-2.3	-2.3	0.5	-1.4	-0.9	-2.0	-0.1	-1.9	-1.2	-2.5	-2.2	-2.0
Mean time to correctly identify matches	2.3	4.4	9.7	0.9	2.1	2.1	0.7	3.1	2.4	2.4	2.2	1.6	2.4	3.0	2.1	2.7	2.8	1.1	2.2	0.0
Headache pain in last month	2.2	3.8	7.8	-1.8	-2.2	-1.8	-0.4	-1.8	-1.7	-2.2	-2.0	-1.8	-2.2	-2.8	-1.4	-2.7	-2.5	-2.1	-2.0	-1.6
Guilty feelings	2.2	3.3	5.9	-1.6	-2.2	-2.0	-1.7	-1.5	-1.2	-1.5	-2.1	-2.1	-2.3	-1.8	-1.2	-1.9	-2.4	-2.3	-1.4	-1.6
Reaction Time	2.1	4.0	10.8	0.5	2.1	1.8	0.4	2.7	2.0	2.3	1.8	1.2	2.5	3.3	1.8	2.8	2.8	0.7	2.1	-0.3
Mouth/teeth dental problems	2.1	3.3	6.5	-1.2	-2.6	-2.4	0.0	-1.3	-1.6	-2.2	-1.5	-2.1	-2.3	-2.4	-0.4	-2.4	-2.4	-1.3	-2.1	-0.9
Alzheimer’s Disease (in father)	2.0	2.2	6.3	2.4	1.0	1.6	-2.0	0.8	1.3	1.6	0.3	1.3	-0.2	1.3	0.9	1.1	1.0	2.5	1.4	2.5
Blood White Count	2.0	15.1	32.4	4.6	3.7	4.2	0.7	4.7	5.5	5.5	2.5	3.3	2.7	5.7	1.6	5.0	4.1	2.5	5.2	0.6
Number of treatments/medications taken	2.0	3.5	9.1	-3.0	-1.8	-2.2	-1.9	-2.1	-2.2	-2.2	-1.6	-2.2	0.1	-1.5	-2.0	-1.4	-1.0	-2.0	-2.5	-1.4
Worrier / anxious feelings	2.0	3.8	9.9	-0.6	-3.0	-2.1	-1.7	-2.9	-2.2	-1.7	-2.3	-2.3	-3.1	-1.4	-1.1	-2.2	-2.0	-0.3	-1.8	0.3
Comparative body size at age 10	2.0	5.4	9.6	2.6	3.1	2.3	1.1	3.0	2.4	2.5	2.5	2.5	2.6	2.0	2.3	2.6	2.1	2.4	2.4	1.6
Medication: Omeprazole	2.0	2.3	4.2	-1.7	-1.8	-2.0	-0.2	-1.4	-1.4	-1.7	-0.4	-1.9	-1.5	-1.5	-1.1	-1.7	-1.6	-2.1	-1.9	-1.8
Mean Putamen Volume	1.9	2.2	4.9	2.2	1.1	2.1	-0.3	1.4	1.8	1.7	0.9	1.7	0.1	1.7	1.7	1.2	1.6	1.7	1.9	0.8
Maternal smoking around birth	1.9	2.8	7.8	1.6	1.6	1.4	0.5	2.2	2.4	2.2	0.8	0.8	0.9	2.8	1.5	2.4	1.8	1.6	2.0	0.4
Medication: Lansoprazole	1.9	2.1	4.9	1.7	1.6	1.7	0.4	1.4	1.5	1.8	1.2	1.7	1.1	1.5	-0.3	1.8	1.0	1.7	1.5	2.2
Crohns Disease (2012)	1.8	2.9	5.3	2.1	1.9	2.0	0.6	1.9	2.3	1.9	1.3	2.2	1.2	1.2	1.4	1.7	1.0	2.3	2.1	1.6
Lupus	1.8	2.7	9.2	0.3	-2.7	-1.3	-1.8	-0.2	-0.8	-0.8	-1.9	-1.4	-3.0	-1.6	-2.5	-1.8	-2.5	-0.8	-0.8	-0.7
Number of live births	1.8	2.5	6.0	-1.2	-1.6	-1.7	-2.0	-1.0	-0.9	-1.4	-1.5	-1.2	-2.3	-2.2	-1.4	-2.1	-2.5	-1.4	-1.4	-0.0
Commuting to job workplace: Cycle	1.8	2.2	6.4	-0.9	-1.3	-1.7	1.8	-1.0	-1.2	-1.4	-0.7	-1.3	-0.9	-1.6	-1.3	-1.6	-1.5	-2.5	-1.1	-2.3
Neuroticism (2016)	1.7	2.5	7.1	0.0	-2.3	-2.0	-2.2	-0.7	-1.0	-0.5	-2.4	-2.0	-2.7	-1.0	-1.1	-1.5	-2.4	0.0	-1.1	0.6
Medication for hormone replacement therapy	1.7	1.9	7.7	1.5	1.0	1.7	0.7	1.6	1.0	1.2	1.0	1.4	0.9	1.4	2.8	1.0	2.0	1.2	1.4	-0.2
Neuroticism score	1.7	3.6	12.3	-1.1	-3.0	-2.2	-1.9	-2.1	-1.3	-1.2	-2.0	-2.1	-3.5	-1.3	-1.6	-2.0	-2.5	-1.5	-1.3	-0.0
Financial situation satisfaction	1.7	2.1	4.8	-1.1	-1.6	-1.8	-0.8	-1.0	-1.9	-1.9	-1.5	-1.5	-1.1	-2.2	-0.3	-2.0	-1.8	-0.8	-1.8	-0.1
Fasting Glucose	1.6	1.9	3.5	0.9	1.9	1.1	1.2	1.5	1.4	1.2	1.6	1.6	1.6	1.2	0.7	1.6	1.4	1.3	1.4	1.8
Smoking Status	1.6	3.9	6.7	2.0	2.3	1.6	1.3	2.3	2.2	2.2	1.5	1.8	1.9	2.4	2.2	2.2	2.6	1.6	2.2	1.5
Had other major operations	1.6	1.9	4.8	-0.7	-1.8	-1.5	0.8	-1.7	-1.1	-1.3	-1.9	-1.7	-2.2	-1.0	-1.6	-1.8	-1.0	-1.1	-1.3	-0.3
Time employed in main current job	1.6	1.8	3.9	-1.9	-1.0	-1.3	-0.9	-2.0	-2.0	-1.9	-0.8	-1.5	0.3	-1.0	-1.8	-1.1	-0.3	-1.0	-2.0	-1.0
Mouth/teeth dental problems: Dentures	1.6	2.8	6.2	0.8	2.0	1.6	-1.0	2.3	1.7	2.3	1.4	1.4	1.9	2.4	-0.5	2.5	1.6	1.0	2.0	0.9
Risk taking	1.6	2.3	8.8	-3.0	-1.4	-1.6	-1.1	-1.5	-1.2	-1.6	-1.6	-1.7	-0.0	-1.4	-0.1	-1.4	-0.9	-1.9	-1.5	-1.9
Bipolar Disorder (2018)	1.5	2.4	7.4	0.8	1.6	0.7	-1.9	0.9	0.7	0.9	1.4	0.8	1.4	1.8	2.7	1.5	2.2	2.3	0.7	2.2
Chronotype (morning person)	1.5	3.4	12.7	-3.6	-0.9	-2.2	-1.9	-2.3	-2.2	-2.4	-1.0	-1.9	0.6	-1.6	-0.7	-1.2	-1.2	-2.0	-2.2	-1.7
Loud music exposure frequency	1.5	1.7	3.9	-0.8	-1.9	-1.1	-2.0	-1.6	-1.3	-1.1	-1.7	-1.5	-2.0	-0.6	0.0	-1.5	-0.8	-0.9	-1.0	-0.8
Blood clot in the leg (DVT)	1.5	1.9	3.6	-1.1	-1.1	-1.7	1.9	-1.5	-1.8	-1.7	-1.8	-1.4	-0.1	-1.7	-0.9	-1.6	-1.1	-1.0	-1.9	0.1
Medication: Ibuprofen	1.5	1.8	3.8	-2.0	-0.9	-1.9	-1.1	-1.5	-1.9	-1.8	1.0	-0.9	-0.2	-1.4	0.3	-1.3	-0.5	-1.9	-1.7	-1.4
Chest pain or discomfort	1.5	2.2	8.0	-2.8	-0.6	-2.2	-1.2	-1.6	-2.1	-2.1	-0.7	-1.5	1.5	-1.1	0.7	-1.1	0.2	-0.5	-2.1	0.4
Commuting to job workplace: Walk	1.5	1.6	4.8	1.2	1.0	1.6	-0.2	1.8	2.2	2.0	1.1	1.2	-0.5	1.5	-0.2	1.4	0.5	0.1	2.1	-0.1
Mother’s age at death	1.5	1.9	5.9	-2.0	-1.4	-1.1	-0.5	-1.4	-1.2	-1.1	-1.2	-1.4	-0.3	-1.1	-2.4	-1.0	-1.0	-2.0	-1.3	-2.0
Medication: Omeprazole (e.g. Zanprol)	1.5	1.9	3.7	-1.4	-1.6	-1.9	-0.5	-0.9	-1.4	-1.6	-0.2	-1.7	-1.4	-1.6	-1.1	-1.5	-1.8	-1.5	-1.7	-1.0
Schizophrenia vs Biploar Disorder	1.4	1.8	5.2	2.3	1.2	1.3	0.1	2.1	1.8	2.0	0.2	1.4	0.6	1.3	-0.7	1.4	0.4	0.9	2.0	1.0
Blood Eosinophil Count	1.4	11.0	26.4	-3.3	-3.1	-3.9	-3.3	-4.8	-3.6	-3.6	-5.1	-3.5	-2.3	-3.0	-3.0	-3.7	-2.4	-0.6	-4.1	1.8
Impedance of leg (right)	1.4	6.8	14.6	2.2	3.1	3.8	1.2	2.0	3.2	2.7	2.2	3.5	2.4	2.7	2.6	2.8	3.0	2.4	3.1	1.1
Age when periods started (menarche)	1.4	3.4	8.1	1.2	2.6	1.8	0.9	2.5	1.9	1.7	1.8	1.8	2.8	2.0	1.6	2.2	2.1	-0.0	2.0	-0.7
Worry too long after embarrassment	1.4	2.3	6.5	-0.9	-2.3	-1.3	-1.6	-1.4	-1.3	-1.2	-0.8	-1.4	-2.5	-1.4	-1.6	-1.7	-1.8	-1.9	-1.3	-1.1
Average weekly red wine intake	1.4	2.0	9.1	-3.0	-0.7	-1.3	-0.0	-1.7	-2.1	-2.1	-0.2	-1.3	-0.5	-1.3	-0.1	-1.5	-0.6	-1.4	-2.1	-1.1
Type 2 Diabetes (T2D) (2012)	1.3	1.6	7.0	1.0	1.9	0.6	0.2	1.7	0.5	0.7	2.0	1.6	2.6	-0.0	0.9	1.4	0.8	0.9	0.9	0.7
Happiness	1.3	1.6	4.3	-0.5	-1.8	-1.2	-0.8	-0.9	-1.1	-1.2	-1.6	-1.5	-2.1	-1.1	-0.7	-1.6	-1.6	-1.0	-1.1	-1.0
Mouth/teeth dental problems: Loose teeth	1.3	1.5	4.5	1.4	1.3	1.8	1.0	1.4	2.1	1.3	1.5	1.9	0.6	0.8	0.2	0.8	1.1	0.4	1.7	0.1
Deep venous thrombosis (DVT) (self-reported)	1.3	1.7	3.3	-0.9	-1.1	-1.6	1.8	-1.5	-1.6	-1.5	-1.5	-1.3	-0.4	-1.6	-1.1	-1.5	-1.1	-1.0	-1.8	0.2
Neuroticism (Nagel 2018)	1.2	2.8	10.2	-1.2	-2.8	-1.6	-2.6	-1.8	-0.8	-0.7	-1.9	-2.1	-3.2	-0.1	-1.4	-1.2	-1.4	-1.5	-1.1	-0.7
Other serious medical condition/disability diagnosed by doctor	1.2	1.6	4.5	-2.1	-1.3	-0.8	-1.3	-1.8	-0.9	-1.2	-0.2	-0.6	-1.4	-1.2	0.3	-1.8	-0.3	-2.0	-0.7	-1.7
High blood pressure (mother)	1.2	1.7	3.3	-1.3	-1.3	-1.1	0.2	-1.3	-1.5	-1.5	-1.7	-1.5	-1.8	-1.4	-0.1	-1.6	-1.6	-1.1	-1.4	-1.3
Prospective memory result	1.2	1.5	5.3	2.3	1.0	1.2	1.0	1.5	1.4	1.6	1.0	1.1	0.5	1.3	0.6	1.2	1.2	1.1	1.4	1.2
Exposure to tobacco smoke at home	1.2	1.3	3.5	0.8	1.0	1.0	1.9	1.6	1.4	1.3	1.1	1.4	1.0	1.0	1.3	1.2	0.9	0.2	1.4	0.5
Alcohol intake frequency.	1.2	2.9	6.7	1.9	1.6	2.0	0.6	1.7	2.6	2.2	2.0	2.1	0.5	1.5	1.8	1.6	1.3	1.3	2.5	0.7
Leg fat-free mass (right)	1.2	6.3	11.8	-2.8	-2.5	-3.4	0.1	-2.5	-3.4	-3.4	-1.8	-3.0	-1.5	-2.9	-0.6	-3.1	-2.1	-2.8	-3.3	-1.6
Loneliness, isolation	1.2	1.7	5.0	-1.7	-1.4	-2.2	-1.0	-0.9	-1.1	-0.8	0.2	-1.6	-0.7	-0.8	-1.7	-0.6	-1.8	-2.2	-0.9	-1.2
Osteoporosis (self-reported)	1.2	1.5	3.6	-0.7	-1.5	-1.5	-0.3	-1.9	-1.5	-1.0	-1.6	-1.5	-1.6	-0.6	-1.7	-1.3	-0.8	-1.2	-1.2	-0.4
Breast Cancer	1.1	2.7	5.4	-1.4	-1.8	-2.2	0.2	-1.1	-1.9	-1.6	-1.9	-2.1	-0.9	-1.6	-2.3	-1.8	-1.5	-1.9	-1.8	-1.6
Average weekly spirits intake	1.1	1.3	3.9	-1.2	-0.9	-1.7	-1.0	-1.4	-1.2	-1.1	-1.9	-1.7	-0.3	-0.2	-2.0	-0.8	-0.2	-0.9	-1.2	-0.2
Serious illness, injury or assault to yourself	1.1	1.4	4.6	0.5	1.2	1.5	0.1	1.0	1.4	1.8	0.3	1.1	0.8	2.2	0.0	1.6	1.5	0.7	1.6	0.5
Had menopause	1.1	1.3	3.8	-1.4	-1.2	-1.2	0.1	-0.4	-1.4	-1.7	-0.6	-1.1	-0.4	-1.9	-0.6	-1.4	-1.3	-1.2	-1.6	-0.8
Medication for pain relief, constipation, heartburn	1.1	2.0	5.0	1.8	1.2	1.6	2.2	1.6	1.7	1.4	-0.1	1.3	0.7	1.2	1.6	1.1	1.2	1.7	1.7	0.9
Medication: Aspirin	1.1	1.5	4.2	-0.4	1.6	1.3	-1.9	0.5	0.6	1.1	1.1	0.8	2.1	1.6	-0.7	2.0	1.2	0.9	0.8	0.4
Leg predicted mass (right)	1.1	6.1	11.5	-2.8	-2.4	-3.3	0.0	-2.5	-3.4	-3.3	-1.8	-3.0	-1.5	-2.8	-0.7	-3.0	-2.0	-2.8	-3.3	-1.6
Alcohol drinker status: Previous	1.1	1.2	5.6	-1.2	-1.4	-0.4	0.7	-0.8	-0.8	-1.1	-0.6	-0.9	-1.2	-1.2	-0.5	-1.1	-1.3	-1.5	-0.7	-2.4
Neuroticism	1.0	2.5	10.3	-1.1	-2.6	-1.5	-2.1	-1.7	-0.6	-0.5	-1.9	-1.9	-3.2	-0.3	-1.4	-1.3	-1.6	-1.4	-0.7	-0.7
Hand grip strength (right)	1.0	2.8	6.8	-1.0	-1.2	-1.9	0.7	-1.7	-2.0	-2.5	-1.4	-1.4	-0.8	-2.5	-0.5	-2.6	-1.3	-2.2	-2.1	-1.7
Sitting height	1.0	6.8	13.7	-2.7	-2.6	-2.8	-0.3	-2.5	-3.7	-3.6	-1.8	-2.5	-1.9	-3.2	-0.7	-3.6	-2.2	-3.1	-3.3	-2.0
Pain all over the body in last month	1.0	1.0	4.5	-1.6	0.6	-0.6	1.7	0.0	-0.3	-0.6	1.5	0.1	1.2	-0.2	2.1	-0.1	0.5	-1.2	-0.2	-1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	3.7	-1.2	-1.9	-1.1	-0.2	-0.4	-0.9	-0.9	-1.1	-1.1	-1.5	-1.2	-1.4	-1.4	-1.7	-1.6	-0.8	-1.4
Medication: Ventolin 100micrograms inhaler	1.0	1.3	3.0	-1.6	-0.6	-1.2	-0.8	-1.3	-1.7	-1.5	-0.6	-0.9	0.1	-1.7	-1.0	-1.0	-1.2	-0.4	-1.5	0.0
Medication: Allopurinol	1.0	1.3	4.4	2.1	-0.2	1.2	0.3	1.0	1.7	1.6	-0.7	0.4	-1.7	1.5	-0.4	0.6	0.4	1.1	1.4	0.8
Forced expiratory volume in 1-second (FEV1), predicted	1.0	2.0	4.8	-1.5	-1.2	-1.4	1.4	-1.6	-1.9	-1.9	-2.2	-1.6	-0.3	-1.5	-0.6	-1.5	-1.1	-1.3	-2.0	-0.7
Mood swings	1.0	1.8	5.3	-0.6	-2.2	-1.6	-0.4	-0.9	-0.9	-0.9	-2.2	-1.7	-2.3	-1.1	-1.0	-1.5	-2.0	-0.9	-0.8	-0.4
Medication: Gliclazide	1.0	1.2	5.0	-1.2	-1.0	-0.7	-0.8	-0.8	-1.0	-0.8	-0.8	-1.4	-0.6	-0.4	-1.5	-0.6	-0.9	-1.6	-1.0	-2.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.1	7.6	2.8	0.9	1.8	-1.4	0.2	1.2	1.3	-0.3	1.2	-0.4	1.5	0.6	1.0	1.4	2.6	1.2	2.4
Age started oral contraceptive pill	1.0	1.3	3.8	-1.9	-0.6	-1.3	-1.1	-1.5	-1.8	-1.6	-1.0	-1.3	0.5	-0.7	0.3	-1.0	0.1	-0.7	-1.7	-0.1
Myopia	1.0	1.5	3.7	-1.2	-1.4	-1.4	-0.9	-0.7	-0.7	-1.0	-0.2	-1.0	-1.7	-1.7	-1.3	-1.6	-1.9	-1.4	-1.1	-0.7
Prostate Cancer	0.9	1.2	4.5	-1.5	-0.2	-0.9	-1.0	-2.1	-1.4	-1.1	-1.8	-0.8	0.6	0.0	-0.8	-0.7	1.0	0.4	-1.4	1.2
Age at First Birth	0.9	1.4	3.4	1.3	0.6	1.9	1.5	1.2	1.5	1.4	1.7	1.5	-0.6	1.3	-0.1	1.1	0.6	0.4	1.5	0.6
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	4.9	0.4	1.4	0.5	-0.7	0.5	0.3	0.5	2.2	1.3	1.0	0.2	1.1	0.8	0.6	1.0	0.7	1.5
Medication: Metformin	0.9	1.2	3.2	-1.3	-1.2	-1.2	-1.8	-0.6	-0.6	-0.9	-1.0	-1.3	-1.0	-1.2	-1.3	-0.8	-1.8	-1.0	-0.9	-0.7
Leg fat-free mass (left)	0.9	4.6	9.0	-2.6	-1.9	-2.8	0.2	-2.3	-3.0	-3.0	-1.3	-2.5	-0.9	-2.5	-0.1	-2.6	-1.4	-2.6	-2.9	-1.7
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	3.2	-1.4	-1.0	-0.4	-0.7	-0.8	-0.8	-1.0	-0.7	-0.7	-0.5	-1.3	-1.8	-1.1	-1.1	-1.5	-0.9	-1.4
Impedance of leg (left)	0.9	4.6	11.0	2.0	2.4	3.3	1.1	1.9	2.7	2.3	1.4	2.9	1.6	2.3	1.9	2.3	2.3	2.2	2.6	1.3
Leg predicted mass (left)	0.9	4.7	9.3	-2.6	-1.9	-2.9	0.4	-2.3	-3.0	-3.0	-1.2	-2.4	-0.8	-2.6	0.0	-2.7	-1.4	-2.7	-2.9	-1.8
Nervous feelings	0.9	1.7	4.3	-1.0	-1.9	-1.1	-1.3	-2.1	-1.4	-1.2	-1.6	-1.2	-1.9	-1.0	-0.4	-1.5	-1.3	-0.1	-1.3	0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.0	4.8	-1.1	-1.7	-0.6	-1.8	-0.8	-1.1	-1.6	-2.2	-1.1	-1.3	-1.8	-1.5	-1.9	-1.3	-1.1	-1.5	-1.1
Lung cancer (father)	0.9	1.1	3.6	0.8	1.5	1.0	-0.6	0.8	0.5	0.9	1.3	1.2	0.9	0.5	0.7	1.0	0.9	1.6	0.8	1.9
Shortness of breath walking on level ground	0.9	1.1	3.3	-1.4	-1.0	-0.9	0.4	-0.4	-1.6	-1.5	-0.5	-0.9	-0.3	-1.8	0.1	-1.2	-1.4	-0.9	-1.5	-0.5
Number of full sisters	0.9	1.1	4.5	0.2	1.4	0.5	0.1	0.2	-0.0	0.3	1.1	0.8	2.1	1.0	1.7	1.1	1.6	1.3	0.3	0.8
Back pain experienced in last month	0.9	1.4	5.2	-0.9	-1.0	-1.2	0.1	-2.3	-1.9	-1.4	-0.4	-1.0	-1.1	-1.2	-0.9	-1.2	-1.1	-0.3	-1.6	0.7
Medication: Aspirin	0.9	1.2	4.3	-0.5	1.5	1.1	-1.4	0.5	0.4	1.0	1.1	0.7	2.1	1.5	-0.8	1.9	1.2	0.7	0.7	0.2
Eye problems/disorders: Glaucoma	0.9	1.0	3.6	0.3	-1.2	-0.9	-1.9	-1.2	-0.8	-0.4	-1.8	-1.1	-1.5	-0.3	-0.6	-0.8	-1.0	0.5	-0.8	0.9
Unable to work because of sickness or disability	0.9	1.2	4.0	0.6	1.3	1.3	1.4	1.6	0.1	0.9	2.0	1.0	1.4	0.8	0.2	1.2	0.9	-0.3	1.0	-1.3
Depressed Affect (Nagel 2018)	0.8	1.7	4.5	-1.0	-2.1	-1.3	-1.0	-1.5	-0.4	-0.6	-1.6	-1.8	-2.1	-0.4	-0.8	-1.1	-1.2	-1.7	-0.9	-1.1
Ovarian Cancer	0.8	1.1	2.9	-1.2	-1.2	-0.9	-0.8	-0.3	-1.0	-1.0	-1.7	-1.4	-0.7	-0.7	-0.9	-1.1	-0.7	-1.5	-1.1	-1.4
Height	0.8	14.8	41.7	-4.0	-3.3	-4.0	1.0	-6.5	-5.4	-5.5	-3.0	-3.7	-2.4	-3.9	-1.1	-5.1	-1.4	-4.3	-4.9	-2.3
Diabetes (father)	0.8	1.0	3.9	0.2	1.0	0.3	1.7	0.7	0.7	0.7	1.2	0.3	1.2	1.3	2.0	1.3	1.1	0.3	0.7	-0.5
Alcohol intake versus 10 years previously	0.8	1.2	3.5	1.7	-0.3	1.0	-0.2	1.1	1.9	1.7	-1.7	-0.1	-1.1	1.4	-1.0	0.8	0.1	0.8	1.1	0.9
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	3.5	-1.2	-0.5	-0.4	-1.9	-1.6	-0.9	-0.9	-1.6	-0.8	-0.3	-0.5	-1.5	-0.6	-0.4	-0.5	-0.9	-0.6
Depression (self-reported)	0.8	1.0	3.1	-0.8	-1.0	-0.7	0.1	-1.3	-0.7	-0.8	-0.3	-0.7	-0.9	-1.2	-1.8	-1.1	-1.3	-1.6	-0.9	-0.9
Pulse wave Arterial Stiffness index	0.8	0.9	4.5	-1.1	-0.2	-0.9	-2.1	-1.6	-0.9	-1.0	-0.7	-0.8	1.1	-0.1	-0.3	-0.3	0.7	-0.7	-1.2	-0.4
Birth weight of first child	0.8	1.4	3.6	1.3	0.9	0.4	0.0	1.9	1.0	1.4	1.3	0.8	1.3	1.7	1.1	1.4	1.8	0.9	1.3	0.9
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	7.1	-0.2	1.1	0.6	1.7	1.1	0.4	-0.2	2.6	1.4	0.3	-0.5	2.7	-0.3	0.7	-0.6	0.5	-0.7
Number of children fathered	0.8	0.9	3.5	1.5	1.0	0.2	0.0	1.8	0.8	0.4	1.0	0.8	0.8	0.1	0.7	0.7	0.3	1.6	0.3	1.9
Health satisfaction	0.8	1.0	2.0	-1.1	-1.4	-1.4	-0.2	-1.1	-1.3	-1.2	-0.9	-1.1	-1.1	-1.1	-0.2	-1.3	-1.1	-0.7	-1.0	-0.3
Medication: Blood pressure	0.8	1.4	7.5	-0.2	-1.4	-0.5	-0.6	-1.7	-0.9	-0.2	-2.7	-1.5	-0.5	0.3	-2.6	-0.1	-0.6	-0.1	-0.8	0.2
Number of self-reported non-cancer illnesses	0.8	1.4	4.7	-2.2	-0.3	-1.7	-0.7	-1.1	-1.4	-1.4	-0.5	-1.2	1.0	-1.4	-1.3	-0.7	-0.9	-1.1	-1.6	-0.3
Medication: Atorvastatin	0.8	1.0	3.2	1.4	0.8	1.1	-0.2	0.7	1.0	1.5	-0.1	0.4	0.2	1.5	-0.1	1.6	0.5	1.8	1.3	1.0
Cholesterol lowering medication	0.8	1.2	4.6	0.0	1.3	0.6	1.1	1.7	0.6	0.7	2.2	0.9	1.5	0.3	2.1	1.1	0.7	0.7	0.6	0.4
Worry (Nagel 2018)	0.7	1.4	4.8	-0.8	-1.9	-1.3	-1.7	-2.1	-0.6	-0.5	-1.1	-1.5	-2.2	0.3	-0.9	-0.7	-0.7	-0.1	-0.7	0.5
Waist Hip Ratio (WHR)	0.7	3.1	7.0	0.6	2.3	2.4	2.4	1.9	2.0	1.7	2.3	2.6	2.1	0.6	1.1	1.7	0.9	1.1	2.1	0.5
Sensitivity / hurt feelings	0.7	1.2	8.6	0.2	-1.6	-0.3	-1.5	-0.0	0.0	0.4	-1.5	-1.0	-2.9	0.2	-0.9	-0.5	-1.4	0.2	-0.1	1.0
Hearing difficulty/problems: Yes	0.7	1.1	4.3	0.1	1.2	2.1	-0.8	0.2	0.8	0.8	0.6	1.9	0.7	0.4	1.4	0.6	1.1	1.1	0.9	1.6
Systolic blood pressure, automated reading	0.7	2.0	4.1	1.9	0.7	2.0	2.0	1.2	1.7	1.9	0.6	1.1	0.4	2.0	-0.6	1.9	1.1	1.4	1.8	0.2
Pack years adult smoking proportion	0.7	1.0	3.6	-1.1	0.8	0.1	0.1	1.1	0.6	-0.2	1.6	0.8	1.0	-1.5	-1.4	-0.2	-1.0	-1.9	0.0	-1.3
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	3.2	1.2	-0.2	0.6	-0.6	-0.8	0.4	1.1	-0.5	0.4	-1.8	0.7	-1.0	0.2	-0.3	1.1	0.8	1.4
Stomach or abdominal pain in last month	0.7	0.9	1.9	1.1	0.8	1.4	0.3	0.5	1.4	1.1	0.1	0.7	0.9	1.3	0.8	1.1	1.3	0.4	1.2	-0.3
Gout (self-reported)	0.7	1.0	3.4	1.8	0.1	1.0	1.0	0.1	1.4	1.4	-0.6	0.5	-0.9	1.6	0.4	0.7	0.9	1.4	1.1	0.9
Pulse wave peak to peak time	0.7	0.8	4.9	1.0	0.3	0.9	2.2	1.5	0.8	0.8	0.8	0.9	-1.0	-0.1	0.5	0.2	-0.6	0.6	1.1	0.3
Ever had bowel cancer screening	0.7	0.8	3.3	-1.8	-0.7	-1.1	-0.3	-0.1	-0.6	-0.6	-0.1	-0.9	0.1	-0.9	-1.2	-0.4	-1.2	-1.4	-0.6	-1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.9	1.7	0.9	0.9	1.2	0.8	1.3	0.6	1.0	1.2	1.3	0.7	0.5	0.2	1.1	0.4	1.1	1.1	1.2
Whole body water mass	0.7	3.8	8.0	-2.4	-1.6	-2.6	0.1	-1.7	-2.8	-2.8	-1.1	-2.2	-0.6	-2.3	0.1	-2.4	-1.2	-2.6	-2.7	-1.5
Tinnitus: Yes, now most or all of the time	0.7	0.9	2.3	1.3	1.2	1.0	-0.2	0.7	1.1	0.5	-0.1	1.4	1.3	-0.0	0.8	0.4	0.6	1.2	0.7	1.5
Pack years of smoking	0.7	1.0	3.3	-0.8	1.1	0.4	0.1	1.3	0.9	0.1	1.8	1.2	1.3	-1.2	-1.3	0.1	-0.7	-1.7	0.3	-1.1
Body Mass Index (BMI) (2010)	0.6	0.9	2.9	0.1	1.0	0.5	-1.7	0.9	0.6	0.9	1.2	0.9	1.1	1.2	0.5	1.2	1.1	0.6	0.7	1.2
HbA1C	0.6	0.6	2.0	0.4	0.5	1.0	0.6	1.4	0.9	0.9	1.1	1.1	0.7	0.1	0.1	0.6	0.1	-0.8	0.9	-0.8
Primary Biliary Cirrhosis	0.6	0.8	3.0	-0.1	-1.1	-0.5	-0.4	-0.3	-0.7	-0.5	-1.7	-1.2	-1.7	-0.4	-1.6	-0.8	-1.2	-0.4	-0.9	0.3
Relative age voice broke	0.6	1.0	3.0	1.7	0.8	0.9	-0.2	1.6	1.2	1.1	0.7	1.0	0.8	0.7	-0.4	1.0	0.7	0.9	1.1	1.2
Qualifications: CSEs or equivalent	0.6	0.8	2.1	-0.3	-0.8	-0.8	-1.0	-1.0	-0.8	-0.8	-1.4	-0.6	-0.9	-1.2	-0.7	-1.2	-1.2	-0.2	-0.9	0.9
Medication: Cholesterol lowering	0.6	0.9	7.0	0.2	0.2	-0.1	-2.6	-0.5	0.0	0.6	-1.2	-0.5	0.9	0.7	-2.0	0.9	-0.2	1.0	0.0	0.7
Standing height	0.6	5.9	13.0	-2.5	-1.9	-2.3	1.1	-3.1	-3.4	-3.6	-1.9	-2.0	-1.3	-2.9	-0.1	-3.4	-1.1	-3.4	-3.0	-2.1
Arm fat-free mass (right)	0.6	3.1	6.6	-2.5	-1.2	-2.3	0.4	-1.3	-2.6	-2.5	-1.1	-1.9	-0.3	-2.1	0.1	-2.1	-1.2	-2.4	-2.5	-1.3
Arm predicted mass (right)	0.6	3.3	6.4	-2.5	-1.4	-2.4	0.6	-1.1	-2.5	-2.5	-1.0	-2.0	-0.3	-2.2	0.1	-2.2	-1.4	-2.5	-2.5	-1.4
Age at last live birth	0.6	0.9	2.9	1.7	0.3	1.2	0.0	1.1	1.5	0.8	-1.0	0.6	-0.5	0.6	-0.3	0.4	0.1	1.5	0.8	1.3
Family relationship satisfaction	0.6	0.8	2.6	-0.7	-0.9	-0.8	-1.5	-0.9	-0.4	-0.0	-1.6	-1.1	-0.9	0.8	-1.6	-0.0	0.0	0.1	-0.5	0.9
Illnesses of father: Heart disease	0.6	0.9	2.7	0.6	0.9	0.6	-1.4	0.4	0.3	0.7	0.9	0.8	0.9	0.8	1.6	0.7	1.2	1.5	0.6	1.1
Whole body fat-free mass	0.6	3.6	7.7	-2.3	-1.5	-2.5	0.2	-1.7	-2.8	-2.7	-1.1	-2.1	-0.5	-2.2	0.2	-2.3	-1.1	-2.5	-2.6	-1.4
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.0	-0.9	-0.6	-0.7	0.3	-0.3	-0.3	-0.9	0.8	-0.1	-0.3	-1.2	0.8	-1.1	-0.5	-1.4	-0.5	-1.2
Hearing aid user	0.6	0.6	1.6	0.6	0.6	1.3	1.0	0.8	1.3	0.8	0.3	1.1	0.9	0.5	0.8	0.6	0.8	0.1	0.9	-0.6
Pain type(s) experienced in last month: Hip pain	0.6	0.8	1.4	-1.0	-0.7	-1.2	-0.9	-1.1	-1.2	-0.9	0.8	-0.9	-0.9	-0.7	-0.6	-0.8	-0.6	-1.1	-1.0	-0.7
Supplements: Fish oil (including cod liver oil)	0.6	0.8	4.1	1.6	0.5	0.8	-0.9	0.2	0.9	0.9	-0.6	0.5	-0.5	0.8	0.3	0.5	0.4	1.4	0.6	2.0
Tanning	0.5	6.5	14.6	-3.8	-2.0	-2.6	-0.7	-2.0	-3.3	-3.4	-0.8	-2.7	-0.6	-2.9	-0.8	-2.6	-1.8	-3.6	-3.3	-3.8
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	2.8	-0.2	-1.4	0.1	-1.4	-0.0	-0.4	-0.8	-1.5	-0.6	-1.7	-1.2	-1.0	-1.4	-1.2	-0.9	-0.7	-1.4
Multivitamins +/- minerals	0.5	0.6	3.6	0.3	-0.4	-0.1	-0.2	0.1	-0.2	-0.4	-1.9	-0.5	-1.1	-1.2	-1.0	-0.9	-1.5	0.2	-0.5	0.5
Illnesses of siblings	0.5	0.6	2.2	-0.6	-0.9	-0.8	0.6	-0.0	-0.7	-0.9	0.1	-0.9	-0.7	-0.6	-0.7	-0.8	-0.6	-1.5	-0.9	-1.3
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.9	1.4	0.5	0.4	0.1	0.7	0.8	1.0	1.1	0.8	-0.1	0.5	1.0	0.8	0.1	1.4	1.0	1.7
Trunk predicted mass	0.5	2.6	5.9	-2.0	-1.2	-2.1	0.2	-1.4	-2.4	-2.3	-0.8	-1.7	-0.3	-1.9	0.4	-2.0	-0.8	-2.3	-2.2	-1.4
Glaucoma (self-reported)	0.5	0.6	2.9	1.1	-0.1	0.1	-1.7	-0.8	0.0	0.6	-0.8	-0.0	-0.7	0.6	-0.1	0.1	0.1	1.2	0.2	1.6
Medication: Amlodipine	0.5	0.7	1.9	-0.9	-1.1	-1.2	0.1	-0.2	-0.4	-0.6	-0.4	-0.9	-0.5	-1.0	-1.1	-0.7	-1.1	-1.4	-0.7	-0.8
Exposure to tobacco smoke outside home	0.5	0.7	2.6	-0.4	-0.8	-1.1	1.6	-0.4	0.4	-0.2	0.0	-0.4	-1.0	-1.0	-0.4	-0.9	-1.3	-1.4	0.0	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.9	-0.3	-1.2	-0.8	0.6	-0.3	-0.7	-0.6	-1.4	-0.9	-1.2	-0.5	-0.4	-0.8	-1.1	0.0	-0.6	0.5
Emphysema/chronic bronchitis	0.5	0.6	1.8	-1.3	-0.2	-0.8	-1.0	-0.6	-1.0	-1.0	0.6	-0.2	0.7	-1.3	-0.1	-0.5	-0.8	-0.5	-0.8	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	2.6	-0.6	-0.4	0.0	-1.5	-0.8	-0.9	-0.6	-1.2	-0.8	0.3	-0.4	-1.6	-0.2	-0.2	-0.1	-0.9	-0.6
Leg pain on walking	0.5	0.6	2.6	0.0	1.1	0.3	-0.7	0.2	0.1	0.4	1.5	0.9	0.8	0.4	0.4	0.8	0.9	0.6	0.4	1.6
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.2	1.5	0.8	0.8	-0.0	-0.4	0.5	0.9	0.3	0.6	0.1	0.8	0.1	0.9	0.4	1.3	1.0	0.9
Breast cancer (self-reported)	0.5	0.5	2.4	-0.2	1.0	0.7	-0.7	0.5	0.2	0.3	0.4	0.8	0.9	0.7	0.6	0.6	1.1	0.7	0.3	1.6
Average weekly champagne plus white wine intake	0.5	0.7	2.7	0.9	0.9	0.7	1.6	1.2	0.6	0.5	1.6	1.3	0.8	-0.1	0.3	0.3	0.7	-0.3	0.8	-0.2
Commuting to job workplace: Public transport	0.5	0.6	1.3	-0.3	-1.0	-1.1	-0.6	-0.9	-0.9	-0.4	-1.0	-1.1	-0.8	-0.4	-1.1	-0.8	-0.9	-0.5	-0.6	-0.6
Medication: Lisinopril	0.5	0.7	1.7	1.1	0.9	0.7	0.6	0.5	0.3	0.8	0.2	0.5	0.7	1.2	0.7	1.1	0.8	1.3	0.6	1.1
Basal metabolic rate	0.5	2.9	6.3	-2.2	-1.3	-2.2	0.2	-1.5	-2.5	-2.5	-0.9	-1.8	-0.4	-2.0	0.4	-2.1	-1.0	-2.2	-2.4	-1.2
Arm fat-free mass (left)	0.5	2.4	5.6	-2.4	-1.0	-2.0	0.1	-1.1	-2.3	-2.3	-0.8	-1.6	-0.1	-1.8	0.3	-1.8	-0.8	-2.2	-2.2	-1.2
Number of operations (self-reported)	0.5	0.7	2.2	-1.5	-0.7	-0.7	0.5	-1.0	-1.2	-1.1	-0.8	-0.9	0.1	-0.6	0.4	-0.8	-0.3	-0.8	-1.1	-0.9
Average weekly beer plus cider intake	0.5	0.7	2.0	1.4	0.1	0.5	0.1	1.0	1.4	1.3	-0.9	-0.0	0.4	1.4	0.3	1.0	0.6	0.5	1.1	0.1
Supplements: Calcium	0.5	0.6	2.5	-0.7	-0.7	-0.7	-0.1	-0.3	-0.8	-0.9	-1.6	-0.9	-0.2	-0.9	0.3	-1.0	-0.7	-0.2	-1.0	-0.5
Bipolar Disorder or Schizophrenia	0.4	1.0	3.5	0.3	0.8	0.2	-1.9	0.2	0.0	0.7	0.5	0.3	0.7	1.4	1.5	1.0	1.5	1.4	0.5	1.7
Coronary Artery Disease (CAD)	0.4	0.5	2.0	1.4	0.3	0.8	0.5	-0.3	0.1	0.1	0.0	0.8	-1.0	-0.7	-0.4	-0.4	-0.4	1.1	0.3	1.4
LDL Cholesterol	0.4	0.7	2.5	-1.6	-0.1	-1.2	-0.3	-0.4	-1.2	-1.1	-0.1	-0.8	0.6	-1.2	-0.2	-0.6	-0.8	-0.6	-1.1	-0.2
Lung FVC	0.4	1.9	9.2	2.2	0.8	1.0	2.3	-1.5	0.9	0.2	-0.8	1.2	-0.3	0.1	0.8	-0.3	0.9	2.6	0.6	3.0
Relative age of first facial hair	0.4	0.8	2.0	0.7	0.9	1.1	-0.7	1.4	0.7	0.7	1.1	0.9	1.0	1.0	0.9	1.1	1.2	0.7	0.8	0.7
Vitamin and mineral supplements	0.4	0.5	2.5	-0.1	0.8	-0.0	0.1	-0.3	0.1	0.0	1.6	0.7	1.3	0.6	1.1	0.6	1.2	0.2	0.4	0.6
Taking other prescription medications	0.4	0.7	2.9	-1.7	-0.6	-0.7	-0.5	-1.3	-0.2	-0.6	0.4	-0.3	0.2	-0.6	-1.1	-0.6	-0.2	-1.5	-0.6	-1.0
Medication: Atenolol	0.4	0.5	1.9	-0.5	-1.0	-0.3	-0.4	-0.9	-0.7	-0.7	-1.4	-0.7	-0.5	-0.7	-1.0	-0.7	-0.9	-0.2	-0.8	-0.2
Trunk fat-free mass	0.4	2.3	5.3	-1.9	-1.1	-2.0	0.1	-1.2	-2.3	-2.2	-0.7	-1.6	-0.3	-1.8	0.4	-1.9	-0.8	-2.3	-2.1	-1.2
Father’s age at death	0.4	0.6	2.5	1.1	-1.0	-0.5	1.0	-0.0	0.4	0.1	-1.6	-0.3	-1.5	-0.4	0.0	-0.8	-0.8	0.1	0.3	0.6
Pulse rate	0.4	0.7	6.2	-1.1	-0.2	0.1	-1.2	0.1	0.4	-0.2	0.8	-0.0	0.1	-0.1	-0.3	-0.1	-0.2	-1.8	0.1	-2.5
Noisy workplace	0.4	0.5	3.5	0.9	0.5	0.9	-0.0	-0.3	0.5	0.3	0.0	0.4	-0.1	0.7	1.9	0.2	0.9	0.8	0.4	-0.1
Pulse wave reflection index	0.4	0.5	1.6	-0.2	-0.3	-1.1	-1.3	-1.1	-0.6	-0.6	-1.1	-1.0	0.1	-0.3	-0.2	-0.3	-0.2	0.2	-0.9	0.7
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	2.4	-1.4	-0.9	-1.0	-0.5	-1.5	-1.0	-1.0	-0.5	-0.7	-1.0	-1.1	-0.3	-1.2	-0.7	-0.8	-1.1	-0.4
High blood pressure (siblings)	0.4	0.6	2.5	0.8	0.6	0.9	-0.9	-0.1	0.8	0.7	-0.4	0.8	0.2	0.5	1.0	0.5	0.5	1.6	0.8	1.1
Pulse rate, automated reading	0.4	1.2	9.9	-1.8	0.3	0.3	-1.4	-0.8	0.6	-0.1	0.6	-0.1	0.9	0.5	0.1	0.2	0.7	-1.8	0.3	-3.1
Suffer from ‘nerves’	0.4	0.7	6.6	0.8	-0.0	-0.1	-0.0	-0.6	0.3	0.6	0.3	0.4	-0.8	0.6	0.5	0.4	0.2	1.5	0.6	2.6
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.5	1.2	0.6	1.1	0.6	0.6	0.6	0.7	0.0	0.7	0.1	0.6	0.9	0.6	0.3	1.1	0.6	0.8
Supplements: Vitamin C	0.4	0.4	4.4	-0.4	-0.0	-0.4	-2.1	-0.5	-0.5	-0.0	-0.3	-0.6	0.3	0.7	0.1	0.6	0.3	0.8	-0.3	-0.0
Smoking status: Previous	0.4	0.6	3.2	-0.9	1.0	-0.1	-1.0	0.8	-0.6	-0.2	1.4	0.6	1.8	-0.5	0.7	0.3	0.2	-0.6	-0.2	-0.6
Friendships satisfaction	0.4	0.5	2.3	0.7	0.3	0.4	0.1	0.4	0.5	0.6	-0.2	0.4	0.1	0.9	0.9	0.4	0.8	1.2	0.5	1.5
Qualifications: nursing, teaching	0.4	0.6	2.0	-0.4	-1.0	-0.0	-0.7	-0.9	-0.3	-0.6	-1.2	-0.5	-1.4	-0.9	-0.3	-1.0	-1.2	-0.4	-0.6	-0.9
Osteoarthritis (self-reported)	0.4	0.6	1.8	0.6	0.7	0.8	-0.7	0.6	0.5	0.7	1.0	0.5	0.5	1.4	0.2	1.1	1.3	0.5	0.6	0.2
Fractured/broken bones in last 5 years	0.4	0.5	2.3	0.6	-0.8	-0.8	-0.2	0.9	-0.4	0.1	-0.6	-0.7	-1.1	-0.4	-1.5	-0.2	-1.3	-0.4	-0.0	-0.1
Heart attack/myocardial infarction (self-reported)	0.4	0.6	2.2	0.5	0.6	1.5	-0.1	0.5	1.3	1.2	0.2	1.1	0.0	0.6	-0.3	0.6	0.2	0.6	1.2	0.3
Intelligence (Savage-Jansen 2018)	0.3	1.0	2.8	1.0	0.5	1.7	-0.4	1.3	0.9	1.2	-0.2	0.6	0.4	1.4	-1.5	1.4	0.8	0.3	1.1	0.1
Alzheimer’s Disease (including proxy)	0.3	0.5	3.3	1.1	0.2	0.6	-0.7	0.1	0.1	0.6	0.0	0.8	0.0	0.1	0.4	0.3	0.0	1.3	0.4	1.8
Rheumatoid Arthritis	0.3	0.5	3.6	0.2	0.6	0.6	1.9	-0.2	0.1	0.4	0.2	0.3	0.7	0.9	0.5	0.6	1.0	0.6	0.4	0.6
Triglycerides	0.3	0.4	1.5	0.4	0.7	1.0	-0.4	-0.4	0.4	0.6	-0.2	0.7	0.9	0.8	-0.1	0.5	1.2	0.9	0.4	0.5
Allergy or Eczema	0.3	0.8	3.5	1.5	0.2	1.2	0.7	-0.0	0.5	1.0	-0.3	0.9	-0.9	0.6	0.7	0.4	0.0	1.3	1.0	1.9
Hypothyroidism (self reported)	0.3	0.7	1.9	-1.4	-0.7	-0.7	-1.4	-1.3	-1.1	-0.9	-0.7	-0.5	-0.5	-0.8	-0.1	-0.9	-0.2	-0.1	-1.0	0.2
Townsend deprivation index at recruitment	0.3	0.4	1.6	-0.6	1.0	0.5	0.4	-0.4	0.2	0.2	1.1	0.8	1.3	0.2	0.4	0.8	0.6	0.6	0.4	0.6
Average weekly fortified wine intake	0.3	0.3	1.2	-0.9	-0.3	-0.3	-0.0	-0.5	-0.5	-0.9	-0.3	-0.0	-0.6	-0.8	-0.2	-1.0	0.1	-1.1	-0.4	-0.4
Fed-up feelings	0.3	0.5	3.3	0.6	-1.2	-0.5	-0.4	-0.3	0.3	0.3	-0.7	-0.5	-1.8	-0.2	-0.6	-0.3	-1.4	-0.1	0.3	0.9
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.6	0.7	0.4	-0.0	1.3	0.4	0.6	0.5	-0.1	0.3	0.4	0.7	0.8	0.0	0.9	-0.1	0.6	0.2
Medication: Levothyroxine sodium	0.3	0.6	1.5	-0.9	-0.9	-0.9	-1.2	-1.0	-0.8	-0.6	-0.5	-0.8	-0.9	-0.5	-0.9	-0.7	-0.5	-0.5	-0.9	-0.0
Past tobacco smoking	0.3	0.5	2.2	0.7	-0.9	0.2	0.5	-1.2	0.3	0.1	-1.2	-0.3	-1.5	0.3	-0.5	-0.3	-0.1	0.8	0.1	0.6
Alcohol usually taken with meals	0.3	0.4	2.6	-0.8	-0.4	0.6	0.6	0.0	-0.1	-0.1	1.1	0.2	-0.5	0.1	-0.1	-0.1	0.2	-1.4	0.0	-1.6
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	1.4	-0.6	-0.6	-1.2	-0.9	-0.9	-0.4	-0.5	-0.7	-1.0	-1.0	-0.5	-0.5	-0.6	-1.0	-0.7	-0.5	0.2
Hearing difficulty/problems with background noise	0.3	0.4	3.0	0.2	-0.0	0.4	-1.6	0.0	-0.1	-0.0	-0.0	0.2	-0.8	-0.1	0.4	-0.1	-0.0	0.8	-0.2	1.7
Qualifications: None of the above	0.3	0.7	1.6	0.2	0.7	0.4	1.1	0.8	1.0	0.9	0.6	0.5	1.2	1.0	1.3	1.0	1.0	0.4	0.9	-0.1
Financial difficulties in last 2 years	0.3	0.4	2.1	1.4	0.1	0.4	1.2	1.5	0.4	0.2	0.3	0.7	0.1	-0.7	0.2	-0.2	-0.6	0.1	0.5	0.1
Heart attack	0.3	0.4	1.9	0.4	0.4	1.4	0.0	0.4	1.1	1.1	0.2	0.9	-0.2	0.5	-0.4	0.5	0.0	0.4	1.1	0.1
Allergy	0.3	0.8	2.2	1.0	0.5	1.0	-0.9	1.5	1.2	1.1	0.2	0.4	0.4	1.5	0.0	1.1	1.0	0.2	1.1	-0.6
Medication: Ramipril	0.3	0.3	2.4	-0.3	-0.6	-0.4	0.6	-0.9	-0.1	0.1	-0.6	-0.8	-0.5	0.3	-1.5	0.0	-0.4	-0.2	-0.2	-0.5
Weight	0.3	1.4	3.9	-2.0	-0.6	-1.3	-0.2	-0.9	-1.6	-2.0	-0.4	-1.1	-0.0	-1.4	0.7	-1.5	-0.4	-1.7	-1.8	-0.7
Length of working week for main job	0.3	0.3	1.5	-0.2	0.4	-0.4	0.9	0.3	-0.3	-0.6	0.8	0.0	1.2	-0.6	0.6	-0.0	0.2	-0.3	-0.4	-0.8
Breastfed as a baby	0.3	0.3	1.5	-0.1	0.8	1.0	-1.2	0.3	0.1	0.1	-0.4	0.4	0.9	0.3	-0.7	0.4	0.6	-0.2	0.0	-0.5
Tense / ‘highly strung’	0.3	0.5	2.3	-0.6	-0.8	-0.8	-0.7	-0.8	-0.2	-0.3	-0.9	-0.9	-0.8	0.2	-1.5	-0.2	-0.5	-0.7	-0.3	0.4
Peak expiratory flow (PEF)	0.3	0.8	2.1	1.0	1.3	1.1	-0.3	1.1	1.0	0.3	0.2	1.4	0.9	0.1	1.5	0.0	0.9	1.1	0.5	0.8
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.5	-0.9	0.7	-0.3	-1.1	-0.8	-0.8	-0.0	0.3	-0.1	1.2	0.5	-0.1	0.5	0.7	-0.2	-0.1	0.0
Birth weight	0.3	0.6	2.1	-0.3	-0.2	0.4	0.1	-0.8	0.0	-0.6	0.3	0.5	-1.1	-0.5	1.3	-1.4	0.9	-1.4	-0.2	-0.8
Leg fat percentage (right)	0.3	1.3	4.8	-0.4	1.4	1.4	-1.0	1.0	1.0	0.3	0.9	1.1	1.8	0.9	2.2	1.1	1.6	0.8	0.4	0.5
Age at first live birth	0.3	0.5	2.7	0.9	-0.5	0.5	0.4	0.2	0.5	-0.2	-1.7	-0.3	-0.8	-0.2	-1.1	-0.3	-0.4	0.9	-0.2	0.8
Eye problems/disorders: None of the above	0.3	0.4	2.5	-0.2	1.1	-0.2	1.6	-0.2	-0.1	-0.7	0.0	0.2	1.4	-0.4	0.7	0.2	0.3	0.2	-0.4	0.3
Migraine (self-reported)	0.3	0.3	3.7	-0.3	-0.7	-0.2	-1.9	-0.1	0.3	-0.1	-0.1	-0.0	-0.8	-0.5	-0.5	-0.4	-0.6	-0.2	-0.1	0.1
Comparative height size at age 10	0.3	1.8	5.3	-1.4	-0.9	-1.5	0.2	-2.1	-2.3	-2.0	-1.0	-1.1	-0.4	-1.4	0.0	-1.8	-0.3	-1.6	-1.8	-0.7
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	2.0	-0.3	-0.2	-0.6	-0.9	-1.4	-1.1	-0.8	0.1	-0.7	0.1	0.3	0.4	-0.2	0.7	0.2	-0.9	0.3
Knee pain experienced in last month	0.3	0.5	1.5	-0.8	-0.1	-0.9	-1.2	-0.7	-0.5	-0.8	0.8	-0.0	0.4	-1.2	-0.4	-0.8	-0.1	-1.0	-0.7	-0.1
Medication for cholesterol	0.3	0.5	2.3	0.3	-0.5	0.1	-1.4	-1.2	-0.3	-0.0	-0.9	-0.2	-0.9	0.2	-1.5	-0.3	-0.4	-0.5	-0.0	-0.3
Mineral and other dietary supplements	0.3	0.4	2.7	-0.3	0.6	-0.1	0.6	0.3	0.4	0.4	1.6	0.7	0.9	0.3	0.2	0.6	0.4	-0.0	0.7	-0.5
Miserableness	0.3	0.6	1.7	-0.3	-1.2	-0.8	0.6	-1.1	-0.3	-0.6	-0.4	-0.5	-1.3	-0.9	-0.0	-1.1	-1.0	-0.6	-0.6	0.5
Medication: Blood pressure	0.3	0.7	2.9	-0.9	-1.0	-1.2	1.7	0.5	-0.4	-0.5	-0.2	-1.0	-0.8	-0.7	0.3	-0.4	-1.3	-0.1	-0.7	0.2
High cholesterol (Self-reported)	0.3	0.5	3.2	-0.7	0.6	-0.7	-1.1	0.3	-0.3	0.1	0.8	-0.3	1.8	0.4	0.4	1.1	0.2	0.4	-0.2	0.4
Illnesses of father: High blood pressure	0.3	0.3	1.4	-0.2	1.0	0.5	-0.2	-0.2	0.4	0.5	-0.5	0.1	1.2	1.1	0.4	0.8	0.9	0.3	0.4	-0.1
Alcohol drinker status: Never	0.3	0.4	3.4	-0.1	-0.1	-0.5	-1.8	-0.7	-0.1	0.3	0.3	-0.4	-0.5	0.7	0.4	0.2	0.2	0.8	0.1	0.5
Ever smoked	0.3	0.6	2.6	-0.4	1.1	-0.5	0.7	1.3	-0.0	0.1	1.6	0.5	1.6	-0.3	0.5	0.5	0.2	-0.6	0.1	-0.3
Ever depressed for a whole week	0.3	0.3	1.1	0.2	-0.7	0.5	1.0	0.2	-0.5	-0.4	-0.3	0.2	-0.9	-0.8	-0.1	-0.8	-0.5	-0.7	-0.1	-0.9
Arm predicted mass (left)	0.3	1.7	3.9	-1.9	-0.8	-1.6	0.3	-0.6	-1.9	-1.9	-0.4	-1.2	0.2	-1.5	0.6	-1.5	-0.6	-2.0	-1.8	-1.1
Depression (Nagel 2018)	0.2	0.3	1.3	1.1	-0.1	0.2	0.7	0.2	0.6	0.8	0.1	-0.1	-1.1	0.7	0.2	0.5	-0.3	0.2	0.7	0.2
Alzheimer’s Disease (in mother)	0.2	0.2	1.2	0.6	0.3	0.8	0.2	-0.2	0.1	0.2	-0.1	0.7	0.1	-0.2	0.2	0.2	-0.1	0.6	0.2	1.1
Verbal and Numeric Reasoning (VNR)	0.2	0.4	3.9	0.0	-0.1	1.0	-1.0	-0.0	0.4	0.3	-0.5	0.1	-0.7	0.2	-2.0	0.3	0.0	-0.3	0.1	-0.0
Schizophrenia (2014)	0.2	0.5	2.6	0.8	0.4	-0.1	-1.6	0.0	0.1	0.8	-0.4	0.1	-0.4	0.7	0.4	0.5	0.1	0.9	0.6	1.4
Blood Red Count	0.2	2.1	11.6	-1.8	0.7	0.1	0.6	-2.1	-0.2	-0.5	-2.4	-0.6	-0.6	0.4	0.6	-1.3	1.4	-3.4	-0.5	-2.5
Heel T-Score	0.2	1.6	14.3	-0.6	-1.4	-0.0	-3.8	0.2	-0.7	-1.0	-1.4	-1.3	-0.4	-0.5	-0.7	-0.8	-0.4	-0.8	-1.4	-1.8
Systolic Blood Pressure	0.2	1.2	3.8	1.3	0.3	1.4	2.0	-0.1	1.4	1.4	0.4	0.7	0.3	1.6	-1.0	1.5	0.6	0.9	1.5	-0.2
Cardiovascular Disease	0.2	0.5	2.1	-0.9	-0.2	-1.1	0.5	-0.2	-0.2	0.3	-1.1	-1.3	0.8	0.3	-1.4	0.8	-0.6	-0.1	-0.3	0.0
Hand grip strength (left)	0.2	0.5	1.3	-0.2	-0.1	-0.8	0.3	-0.3	-0.8	-1.1	-0.6	-0.6	0.0	-0.9	0.3	-1.0	-0.1	-1.1	-0.9	-1.2
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.5	0.4	-0.6	-0.5	0.7	-0.6	0.2	0.2	-0.3	-0.4	-1.2	0.1	-0.9	-0.0	-0.9	-0.5	0.3	0.3
Ever had hysterectomy (womb removed)	0.2	0.2	1.0	-0.8	-0.5	-0.5	1.0	-0.2	-0.3	-0.1	0.9	-0.1	-0.2	-0.4	-0.2	-0.2	-0.1	-0.7	-0.2	-0.0
Medication: Co-codamol	0.2	0.3	1.8	-0.5	0.3	-0.6	-0.3	0.3	0.4	0.2	1.4	0.3	-0.2	-0.2	-0.5	-0.1	-0.3	-1.2	0.4	-0.1
Diabetes (mother)	0.2	0.3	1.4	-0.5	-0.4	-0.1	-0.6	-0.4	-0.3	-0.2	-0.0	-0.7	-0.9	-0.1	-1.2	-0.3	-0.5	-0.7	-0.5	-0.3
Severe depression (siblings)	0.2	0.2	1.1	-0.2	-0.2	0.5	-0.4	-0.0	0.4	0.1	-0.2	-0.2	-1.0	0.5	0.3	0.1	-0.0	-0.4	-0.0	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	1.9	0.6	0.4	-0.2	0.2	0.4	0.1	0.2	1.1	0.1	-0.1	0.1	1.4	0.4	-0.2	0.2	0.4	0.3
Chronic bronchitis/emphysema (father)	0.2	0.2	1.1	-0.6	-0.2	-0.2	0.3	0.1	0.0	-0.2	-0.4	-0.3	-0.0	-0.6	0.4	-0.4	-0.4	-1.0	-0.1	-1.1
Number of incorrect matches in round	0.2	0.4	1.2	-0.8	0.3	-0.4	-0.4	-0.8	-1.1	-0.8	0.5	-0.3	0.9	-0.1	0.7	-0.0	0.4	-0.0	-0.9	-0.4
Forced vital capacity (FVC)	0.2	0.9	4.4	0.3	-0.1	0.1	1.8	-2.1	-0.7	-1.3	-1.6	-0.2	-0.2	-1.1	-0.0	-1.5	0.2	-0.4	-1.0	-0.3
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	2.1	0.1	0.4	0.7	-0.0	0.3	0.1	0.1	0.1	0.4	0.3	0.3	1.5	0.3	0.6	0.0	0.4	-0.5
Diabetes (self-reported)	0.2	0.3	2.4	-0.6	0.0	-0.4	-1.6	0.2	-0.2	-0.4	-0.3	-0.7	0.3	-0.0	-0.4	0.1	-0.2	-0.3	-0.6	-0.1
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	1.6	-0.6	0.2	-0.7	0.7	-1.3	-0.7	-0.6	-0.4	-0.4	0.7	-0.4	-0.5	0.0	-0.5	0.1	-0.6	0.1
Medication: Simvastatin	0.2	0.3	2.0	-0.7	0.4	0.1	-1.3	0.1	-0.1	0.3	0.6	0.1	1.4	0.2	-0.5	0.8	0.1	0.2	0.0	0.1
Fluid intelligence score	0.2	0.4	1.7	0.1	0.8	1.0	-0.5	0.4	0.7	0.6	0.1	0.4	0.8	1.1	-0.3	0.9	1.3	0.4	0.4	0.1
Hip circumference	0.2	1.0	2.6	-1.6	-0.9	-1.3	-1.2	-0.8	-1.2	-1.4	-0.6	-1.1	-0.4	-0.9	-0.2	-1.1	-0.3	-1.2	-1.4	0.1
Falls in the last year	0.2	0.3	1.8	0.2	-0.4	0.2	0.5	-0.3	-0.2	0.3	0.4	-0.0	-1.3	-0.3	-1.3	-0.2	-0.6	-0.9	0.2	-0.3
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	3.0	1.7	0.4	0.9	1.7	-0.4	0.2	-0.3	-1.1	0.6	-0.3	-0.3	0.9	-0.7	0.4	0.8	-0.0	0.5
Illnesses of mother	0.2	0.3	1.1	0.5	0.4	0.2	-0.6	0.6	0.8	0.6	0.4	0.6	0.6	0.5	-1.0	0.4	0.3	-0.2	0.6	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	3.9	2.0	0.6	1.0	1.5	-0.3	0.4	0.0	-0.7	0.9	-0.1	-0.3	0.5	-0.5	0.4	1.0	0.3	1.0
Ever highly irritable/argumentative for 2 days	0.2	0.2	1.2	-0.4	-0.1	-0.1	0.4	0.1	-0.5	-0.6	0.0	0.1	0.3	-1.1	0.3	-0.4	-0.8	-0.6	-0.3	-0.2
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	1.8	0.0	-0.7	0.6	-0.4	-0.5	0.5	-0.1	-0.4	0.1	-1.4	-0.3	-0.5	-0.6	-0.5	-0.8	0.1	-1.3
Chronic bronchitis/emphysema (mother)	0.2	0.2	0.8	-0.6	-0.6	-0.9	0.6	-0.4	-0.1	-0.1	-0.4	-0.7	-0.1	-0.2	-0.5	-0.0	-0.6	0.1	-0.4	-0.1
Forced vital capacity (FVC), Best measure	0.2	0.8	4.4	0.3	0.0	0.1	1.7	-2.1	-0.7	-1.2	-1.3	0.1	0.2	-1.1	-0.1	-1.3	0.2	-0.2	-0.8	-0.0
Number of full brothers	0.2	0.2	0.9	-0.8	0.2	-0.4	-0.8	-0.1	-0.2	0.3	-0.5	-0.3	0.2	0.3	-0.9	0.3	-0.3	-0.6	0.3	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	1.0	0.6	-0.1	0.5	0.4	0.2	0.6	0.8	0.3	0.2	-0.3	1.0	0.3	0.4	0.6	-0.3	0.8	-0.5
Wheeze or whistling in the chest in last year	0.2	0.4	2.7	-0.4	0.7	0.0	0.6	-0.3	-0.0	0.1	1.1	0.5	1.7	0.2	0.1	0.8	0.6	0.4	0.1	0.9
Neck or shoulder pain in last month	0.2	0.3	2.2	0.3	-0.3	0.0	-1.0	0.0	0.3	0.4	-0.3	0.3	-0.8	-0.3	-0.7	-0.2	-0.7	0.6	0.2	1.5
Had major operations	0.2	0.3	1.2	-1.1	-0.2	-0.1	-0.8	-0.9	-0.6	-0.5	0.1	-0.4	0.5	0.2	-0.7	0.2	0.3	-0.2	-0.6	-0.4
Hypertension (Self-reported)	0.2	0.4	2.3	-0.5	-0.7	-0.6	0.9	0.2	-0.3	0.4	-0.9	-1.0	0.1	0.5	-1.5	0.6	-0.5	-0.1	-0.2	0.4
Long-standing illness, disability or infirmity	0.2	0.4	1.2	-0.9	0.1	0.9	0.2	-0.5	0.1	-0.0	1.1	0.8	-0.5	-0.2	1.0	-0.4	0.4	-0.8	0.3	-0.6
Diabetes diagnosed by doctor	0.2	0.3	1.1	-0.2	0.9	0.4	-0.9	0.8	0.7	0.4	0.7	0.3	1.0	0.5	0.0	0.9	0.4	-0.2	0.4	-0.3
Eye problems/disorders: Cataract	0.2	0.2	1.5	-0.1	-0.5	0.1	-0.4	0.6	0.1	0.2	1.2	0.4	-0.5	-0.5	-0.4	-0.3	-0.2	-0.6	0.3	-0.8
Illnesses of father: None of the above (group 1)	0.2	0.3	2.1	0.6	-0.3	-0.6	0.1	0.3	-0.4	-0.1	-0.3	-0.2	-0.4	-0.2	-1.5	-0.0	-0.6	0.2	-0.3	1.0
Ever taken oral contraceptive pill	0.2	0.3	1.8	1.3	0.2	0.2	-1.3	0.6	-0.0	0.3	-0.6	0.2	-0.3	-0.1	0.4	-0.2	-0.0	0.1	0.3	0.4
Leg fat percentage (left)	0.2	0.7	2.7	-0.5	0.9	1.0	-1.1	1.0	0.7	0.1	0.5	0.6	1.3	0.7	1.6	0.8	1.1	0.6	0.1	0.6
Irritability	0.2	0.4	1.5	0.2	-0.9	-0.2	-1.1	0.0	0.2	0.5	-1.2	-0.9	-0.7	1.0	-0.9	0.3	-0.1	-0.3	0.3	-0.3
Vascular/heart problems diagnosed by doctor	0.2	0.4	1.5	-0.2	0.3	0.2	-1.2	-0.9	-0.2	-0.9	0.5	0.6	-0.1	-0.7	1.2	-0.9	0.4	-0.5	-0.3	-0.6
Impedance of whole body	0.2	1.2	3.9	1.2	0.8	2.0	1.3	0.1	1.5	1.0	0.7	1.5	0.1	1.2	1.0	0.9	1.3	1.2	1.3	0.4
Schizophrenia (2018)	0.1	0.1	0.8	-0.3	-0.3	-0.4	-0.9	-0.4	-0.6	0.2	-0.4	-0.3	-0.2	0.4	-0.3	0.1	0.2	-0.1	0.1	0.3
Major Depression (MDD)	0.1	0.2	1.6	0.1	-0.3	-0.2	-0.1	0.5	-0.1	-0.2	0.0	-0.2	-0.6	-0.4	1.3	-0.5	-0.3	-0.0	-0.2	-0.4
Blood Platelet Count	0.1	1.5	5.7	-1.5	-1.2	-0.6	0.9	-1.3	-0.7	-1.4	0.2	-0.1	-0.6	-2.4	-0.0	-1.5	-1.8	-1.6	-1.1	-1.5
BMI	0.1	0.6	2.7	-1.6	1.0	-0.1	-0.1	0.4	-0.2	-0.7	0.7	0.1	1.6	-0.3	0.8	0.1	0.6	-1.1	-0.7	-0.6
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.6	-0.6	0.1	0.0	-0.7	0.8	0.3	0.1	0.0	-0.2	0.2	-0.1	-0.6	0.3	-0.7	-0.7	-0.1	-0.5
Hair Pigment	0.1	3.4	6.9	1.5	2.6	2.0	0.8	2.3	2.3	2.1	2.3	2.2	1.6	2.0	1.0	1.9	2.1	0.7	2.5	0.5
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.9	0.1	0.2	0.1	1.0	-0.0	-0.3	0.1	-0.3	-0.0	0.1	0.3	0.8	-0.1	0.8	-0.1	-0.0	-0.3
Angina	0.1	0.2	0.6	-0.0	0.4	0.4	-0.6	0.5	0.4	0.7	0.2	0.1	0.4	0.4	-0.4	0.7	-0.2	0.2	0.5	-0.3
Trunk fat percentage	0.1	0.2	1.1	-0.8	0.2	0.4	0.1	0.0	0.2	-0.7	0.4	0.2	0.5	-0.2	1.1	-0.2	0.6	-0.4	-0.4	-0.1
High blood pressure	0.1	0.4	1.5	-0.2	-0.6	-0.7	0.9	0.5	-0.3	0.5	-0.9	-1.0	0.1	0.6	-1.2	0.7	-0.3	0.3	-0.2	0.7
Hayfever, allergic rhinitis or eczema	0.1	0.2	1.0	0.1	-0.1	0.3	0.5	-1.0	-0.2	0.0	-0.8	0.1	-0.6	0.0	0.1	-0.3	-0.1	0.4	0.1	0.8
Body mass index (BMI)	0.1	0.2	0.8	-0.9	0.3	-0.2	-0.7	0.6	0.1	-0.3	0.6	-0.1	0.7	-0.1	0.9	0.1	0.2	-0.4	-0.4	0.0
Trunk fat mass	0.1	0.5	1.7	-1.3	-0.2	-0.2	-0.1	-0.5	-0.6	-1.3	-0.1	-0.3	0.3	-0.8	0.9	-0.8	0.3	-1.0	-1.1	-0.4
Waist circumference	0.1	0.4	2.1	-1.4	0.1	-0.3	0.2	-0.0	-0.3	-0.9	0.5	0.1	0.5	-1.0	0.8	-0.5	-0.2	-0.6	-0.6	0.1
Hair/balding pattern: Pattern 2	0.1	0.2	0.7	-0.6	0.3	0.0	-0.8	-0.6	0.3	0.0	-0.3	0.1	0.4	0.1	-0.7	0.2	0.1	-0.2	-0.2	0.5
Impedance of arm (right)	0.1	0.5	1.4	1.1	0.3	1.1	0.5	-1.0	0.9	0.3	0.4	0.8	-0.4	0.8	0.7	0.3	1.2	0.8	0.7	0.1
Arm fat percentage (right)	0.1	0.3	1.7	-0.4	0.4	0.3	-0.7	0.1	0.4	-0.2	0.6	0.2	0.6	0.4	1.3	0.3	0.9	0.3	-0.2	0.4
Hair/balding pattern: Pattern 3	0.1	0.1	0.5	0.6	-0.3	0.1	-0.6	0.4	0.2	0.2	0.3	0.4	-0.0	0.2	0.7	-0.1	0.6	0.2	0.4	0.2
Qualifications: A levels/AS levels or equivalent	0.1	0.3	1.0	-0.1	-0.2	0.9	-1.0	-0.7	0.9	0.4	0.4	0.4	-0.7	0.6	-0.7	0.3	0.1	0.1	0.5	-0.6
Impedance of arm (left)	0.1	0.6	3.0	0.1	-1.0	-0.0	0.9	-1.7	-0.1	-0.7	-0.7	-0.4	-1.6	-0.3	-0.3	-0.9	-0.2	-0.2	-0.4	-0.6
Arm fat mass (right)	0.1	0.4	1.6	-1.2	-0.1	-0.6	-0.2	-0.2	-0.6	-1.1	0.4	-0.4	0.3	-0.7	1.2	-0.6	0.1	-0.6	-1.0	-0.1
Hair/balding pattern: Pattern 4	0.1	0.3	1.5	-1.1	0.3	0.0	1.2	-0.1	-0.4	-0.5	-0.3	-0.2	0.3	-0.5	0.1	-0.3	-0.1	-0.5	-0.5	-1.0
Body fat percentage	0.1	0.3	1.6	-0.6	0.5	0.7	-0.3	0.3	0.5	-0.3	0.4	0.5	0.7	0.2	1.2	0.1	0.9	0.1	-0.2	0.3
Qualifications: College or University degree	0.1	0.2	0.9	-0.5	-0.5	0.2	-1.0	-0.6	-0.1	0.0	0.4	0.0	-0.8	0.2	-0.5	-0.2	0.1	-0.7	-0.1	-0.6
Angina (self-reported)	0.1	0.1	0.5	-0.2	0.2	0.2	-0.7	0.3	0.3	0.4	0.1	-0.1	0.2	0.2	-0.5	0.5	-0.4	-0.2	0.3	-0.7
Heart disease (mother)	0.1	0.2	0.9	-0.0	0.1	-0.2	-0.0	0.0	-0.2	0.0	-0.4	-0.5	0.3	0.6	-0.1	0.5	0.3	1.0	-0.2	0.9
Whole body fat mass	0.1	0.4	1.5	-1.2	-0.1	-0.3	-0.5	-0.4	-0.4	-1.1	0.1	-0.3	0.4	-0.6	1.0	-0.7	0.3	-0.8	-1.0	-0.1
Leg fat mass (right)	0.1	0.5	3.2	-1.1	0.5	0.3	-0.7	0.3	0.1	-0.6	0.5	0.2	1.1	-0.1	1.8	-0.0	0.9	-0.3	-0.4	-0.1
Overall health rating	0.1	0.2	1.4	-0.6	-0.4	-0.1	0.1	-0.6	0.2	-0.2	0.4	0.2	-0.3	-0.7	0.3	-0.7	-0.3	-1.2	-0.0	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.2	0.8	0.2	-0.0	-0.3	-0.3	-0.3	-0.1	-0.5	-0.7	-0.0	-0.1	-0.9	-0.4	-0.6	-0.5	-0.0	-0.3	0.1
Arm fat percentage (left)	0.1	0.2	1.0	-1.0	-0.3	-0.3	-0.4	-0.4	-0.1	-0.9	-0.0	-0.5	-0.2	-0.4	0.8	-0.5	0.0	-0.3	-0.9	-0.0
Arm fat mass (left)	0.1	0.6	2.2	-1.5	-0.2	-0.7	-0.1	-0.4	-0.7	-1.3	0.2	-0.7	0.3	-0.7	1.2	-0.8	0.1	-1.0	-1.2	-0.5
Medication: Bendroflumethiazide	0.1	0.2	1.3	0.8	-0.5	-0.2	0.2	-0.3	-0.0	0.2	-1.1	-0.5	-0.1	-0.1	-0.5	0.1	-0.5	0.6	-0.0	0.3
Diastolic blood pressure, automated reading	0.1	0.4	3.2	0.4	-0.8	0.1	1.8	-0.0	0.2	0.4	-0.3	-0.5	-1.0	0.2	-0.4	-0.1	-0.6	-0.2	0.3	-1.0
Basal cell carcinoma (self-reported)	0.1	0.1	0.6	-0.2	0.1	0.2	-0.1	-0.0	0.1	0.0	-0.8	-0.2	0.8	0.5	-0.7	0.3	0.3	0.1	-0.0	-0.3
Heart disease (siblings)	0.1	0.2	0.6	-0.4	-0.6	0.1	0.5	-0.4	-0.4	0.0	-0.7	-0.3	-0.8	-0.1	-0.2	-0.1	-0.3	0.7	-0.2	0.4
Leg fat mass (left)	0.1	0.4	2.1	-1.2	0.2	-0.0	-0.7	0.1	-0.1	-0.8	0.1	-0.1	0.8	-0.2	1.5	-0.2	0.6	-0.4	-0.7	-0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

ITPKC

Models

Trait associations