Best TWAS P=7.28e-11 · Best GWAS P=1.45e-13 conditioned to 6.67e-06
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Testis | PDE4A | 0.20 | 0.02 | enet | 39 | 0.04 | 0.00642 | 7.4 | 6.5 | 7.3e-11 | 0.58 | 0.00 | 0.90 | TRUE |
2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | S1PR5 | 0.05 | 0.04 | lasso | 4 | 0.04 | 0.00052 | 3.7 | -5.5 | 4.2e-08 | -0.16 | 0.04 | 0.19 | TRUE |