Hub : Genes

ADCK4

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adrenal Gland 0.3003 0.0880 1.3e-03 0.069 NA 0.072 NA 0.076 1.8e-03 NA 1.5e-03 NA 1.1e-03
2 GTEx Brain Nucleus accumbens basal ganglia 0.3270 0.0930 1.3e-03 0.008 NA 0.014 NA 0.005 1.9e-01 NA 1.3e-01 NA 2.3e-01
3 GTEx Heart Left Ventricle 0.1688 0.0582 1.1e-03 0.034 NA 0.100 NA 0.063 6.2e-03 NA 5.3e-06 NA 2.8e-04
4 GTEx Nerve Tibial 0.2184 0.0449 1.2e-08 0.230 NA 0.210 NA 0.238 2.6e-16 NA 7.3e-15 NA 7.7e-17
5 YFS Blood 0.0300 0.0103 1.3e-04 0.008 0.013 0.011 0.013 0.010 1.0e-03 2.8e-05 1.4e-04 2.7e-05 1.8e-04
6 TCGA Lung Adenocarcinoma 0.0369 0.0198 4.7e-03 0.029 0.011 0.004 NA 0.014 2.4e-04 1.7e-02 9.0e-02 NA 8.7e-03
7 TCGA Pheochromocytoma and Paraganglioma 0.1960 0.0760 1.0e-05 0.160 0.133 0.143 NA 0.141 6.2e-07 6.3e-06 2.7e-06 NA 3.0e-06
8 TCGA Prostate Adenocarcinoma 0.0864 0.0321 1.9e-09 0.111 0.099 0.112 NA 0.119 1.3e-11 1.7e-10 1.0e-11 NA 1.9e-12

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 1.0 1.5 4.3 1.4 1.6 1.4 0.3 0.3 2.1 -0.7 0.9
Bipolar Disorder or Schizophrenia 0.4 0.9 3.1 1.2 1.2 0.9 0.1 0.2 1.8 -0.3 0.8
Depressed Affect (Nagel 2018) 0.2 0.5 1.3 0.2 1.0 0.4 -0.3 1.0 0.5 1.1 -0.4
Depression (Nagel 2018) 0.3 0.4 1.0 -0.9 -0.1 -1.0 0.3 -0.3 -0.0 -0.7 0.8
Intelligence (Savage-Jansen 2018) 0.5 1.6 3.6 0.5 1.2 -0.6 1.9 1.9 1.1 -0.7 1.4
Neuroticism (Nagel 2018) 0.9 2.0 5.9 0.6 2.0 1.6 0.0 2.4 0.8 1.6 -0.4
Schizophrenia (2018) 0.1 0.1 0.4 0.4 0.4 -0.3 -0.1 -0.1 0.6 0.3 0.4
Schizophrenia vs Biploar Disorder 1.3 1.7 4.6 -1.4 0.4 -1.8 0.9 -0.2 -0.9 -1.6 2.1
Worry (Nagel 2018) 1.1 2.3 10.5 0.5 3.2 1.4 -0.3 1.9 0.6 1.4 -0.3
Alzheimer’s Disease (in mother) 0.2 0.3 0.8 -0.4 -0.5 -0.8 0.6 -0.1 -0.3 -0.9 0.1
Alzheimer’s Disease (in father) 1.1 1.2 2.7 -1.4 0.0 -0.4 1.0 1.2 -0.7 -1.6 1.4
Alzheimer’s Disease (including proxy) 0.6 0.9 3.0 -1.7 0.1 -1.0 0.3 0.0 -1.2 -1.2 0.3
Crohns Disease (2017) 3.5 7.8 23.1 -0.5 -0.4 -2.9 2.9 -1.5 1.4 -4.8 4.2
Irritable Bowel Disease (IBD) 3.8 9.0 26.5 -0.9 -1.4 -3.2 3.0 -1.4 1.2 -5.2 4.5
Ulcerative Colitis (UC) 2.1 4.0 11.6 -0.8 -1.4 -1.9 2.1 -0.8 0.7 -3.4 2.9
Major Depression (MDD) 0.1 0.2 0.7 0.1 -0.8 0.2 -0.2 -0.2 -0.4 0.0 -0.6
Reaction Time 1.9 3.5 9.9 1.9 0.8 -0.6 2.4 0.9 3.1 -1.5 2.3
Verbal and Numeric Reasoning (VNR) 0.2 0.6 2.2 0.7 0.0 0.0 1.5 1.2 0.8 -0.1 0.3
Breast Cancer 0.5 1.3 3.8 0.1 -0.3 1.0 -1.5 0.5 -0.8 1.9 -1.6
Ovarian Cancer 0.3 0.4 1.1 0.5 0.0 0.3 -0.1 0.9 0.4 1.1 -0.9
Prostate Cancer 2.6 3.6 7.9 2.8 2.3 2.1 0.1 1.6 1.9 2.1 -0.6
Age at First Birth 1.0 1.4 3.8 0.2 -0.2 -1.9 1.5 -0.6 0.9 -1.3 1.6
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 1.3 1.8 6.3 2.2 0.7 0.9 1.2 0.1 2.5 -0.3 0.8
Coronary Artery Disease (CAD) 1.3 1.5 5.7 -2.1 0.7 -0.1 -1.0 -0.5 -2.4 -0.7 -0.1
Crohns Disease (2012) 1.6 2.7 7.1 -1.9 -0.1 -1.8 0.6 -1.8 -1.1 -2.7 1.5
Mean Putamen Volume 1.7 1.9 4.1 -0.4 0.5 -1.8 1.4 2.0 -0.1 -1.1 2.0
Fasting Glucose 1.0 1.3 3.8 1.2 -0.1 0.4 1.2 -0.4 1.9 -1.2 1.2
HbA1C 1.1 1.2 5.8 -0.2 -2.4 -0.5 0.4 -1.3 0.2 -1.1 0.7
HDL Cholesterol 2.0 3.3 7.8 -0.9 -0.7 0.6 -2.7 0.5 -1.9 2.4 -2.8
LDL Cholesterol 0.7 1.2 5.6 -0.3 -0.4 0.7 -1.3 -2.4 0.0 0.2 -1.2
Lupus 2.1 3.2 10.9 -1.9 -2.2 -0.3 -1.6 1.2 -3.3 1.1 -0.8
Neuroticism (2016) 1.7 2.4 9.8 -2.3 0.5 0.8 -1.6 0.6 -3.1 0.4 -0.8
Primary Biliary Cirrhosis 0.1 0.2 0.6 0.1 -0.5 0.2 0.1 0.8 -0.1 0.3 -0.5
Rheumatoid Arthritis 0.2 0.2 0.7 0.7 -0.3 0.4 0.3 0.0 0.8 -0.3 0.5
Schizophrenia (2014) 0.1 0.2 0.5 -0.3 0.6 -0.0 -0.0 -0.2 0.0 -0.6 0.7
Triglycerides 0.5 0.9 1.8 1.3 1.0 -0.6 1.3 1.0 0.8 0.1 0.6
Type 2 Diabetes (T2D) (2012) 1.5 1.8 6.7 -1.2 -2.6 -0.4 0.2 -1.6 -0.1 -1.8 0.3
Ulcerative Colitis 1.7 2.4 7.6 -0.3 -0.4 -1.0 2.0 -0.3 0.8 -2.8 2.4
Blood Eosinophil Count 1.2 9.3 18.3 0.8 3.1 4.3 -3.0 2.9 -0.9 4.0 -3.3
Blood Platelet Count 0.2 2.3 5.6 -1.8 1.1 -1.1 -1.2 -1.7 -2.4 0.5 -1.6
Blood Red Count 0.7 7.0 13.3 2.9 2.1 2.0 2.8 3.6 3.4 2.6 0.3
Blood White Count 1.5 11.4 30.8 1.1 0.6 -0.5 5.4 2.9 2.8 -3.6 5.5
Heel T-Score 0.2 1.7 6.0 -0.3 1.3 1.8 0.1 2.4 -1.0 0.9 -1.0
BMI 0.4 2.2 4.2 1.9 -2.0 0.7 0.4 -2.0 2.0 0.4 -0.7
Height 0.7 13.6 41.6 4.1 -2.6 2.7 -3.7 0.4 1.6 6.5 -4.5
Waist Hip Ratio (WHR) 1.0 4.3 13.5 -1.9 -0.5 -2.4 0.7 -3.7 -1.1 -2.7 1.6
Systolic Blood Pressure 0.6 3.1 8.6 -0.5 2.9 1.1 1.8 2.6 0.4 -1.4 1.6
Smoking Status 1.6 3.7 11.4 1.6 -3.4 0.9 1.6 0.6 2.2 -1.5 2.3
Allergy or Eczema 1.0 2.6 7.8 -2.6 0.2 -2.8 0.2 0.1 -1.6 -1.6 1.1
Cardiovascular Disease 0.4 1.2 6.2 0.1 2.5 1.4 -0.1 -0.1 1.0 -0.5 -0.1
Hypothyroidism (self reported) 0.2 0.4 0.8 -0.1 -0.9 0.5 -0.7 0.4 -0.6 0.8 -0.8
Respiratory disease 2.7 5.9 13.3 -0.1 -2.1 1.3 -3.5 -2.8 -1.1 2.6 -3.6
Type 2 Diabetes (T2D) (2018) 0.2 0.3 0.6 -0.6 -0.8 0.6 -0.1 -0.7 -0.5 -0.7 -0.1
Lung FEV1/FVC ratio 1.9 9.6 21.3 -1.5 -4.3 -1.1 3.4 0.8 -0.8 -4.5 4.6
Lung FVC 0.7 3.5 12.9 -2.0 3.6 -2.6 -0.5 1.5 -1.4 -0.2 0.5
Neuroticism 0.7 1.7 4.1 0.1 2.0 1.8 -0.3 2.0 -0.3 1.4 -0.3
Chronotype (morning person) 1.3 3.1 5.4 2.1 1.4 1.5 -1.7 -1.3 1.5 1.9 -2.3
Hair Pigment 0.1 2.9 10.5 1.0 -0.5 -3.2 1.5 -0.1 1.2 -1.3 2.4
Tanning 0.4 4.3 11.7 0.3 -1.8 2.5 -2.0 -2.0 0.1 2.4 -3.4
Hand grip strength (left) 0.4 1.0 2.3 1.2 -0.9 1.0 -0.6 0.8 0.4 1.5 -1.0
Number of treatments/medications taken 1.3 2.3 6.2 1.3 1.7 1.4 -1.1 0.9 0.8 2.5 -1.9
Average weekly spirits intake 2.3 2.9 5.1 1.9 2.3 1.9 -0.1 1.9 1.7 2.1 -0.6
Sensitivity / hurt feelings 0.9 1.5 6.5 -1.0 1.6 0.9 0.2 2.5 -1.1 -0.2 0.3
Frequency of depressed mood in last 2 weeks 0.3 0.4 1.7 -0.4 1.3 -0.6 -0.3 -0.3 0.5 -0.0 0.5
Hearing difficulty/problems: Yes 0.8 1.2 2.4 -0.7 -0.9 -1.2 1.2 -1.6 -0.4 -1.5 0.8
Relative age of first facial hair 0.4 0.9 2.0 1.0 -1.2 -0.8 0.3 -0.5 1.4 -0.8 0.9
Other serious medical condition/disability diagnosed by doctor 0.8 1.0 3.3 1.1 -0.9 0.4 -1.1 -0.5 0.1 1.8 -0.9
Ever used hormone-replacement therapy (HRT) 0.3 0.4 1.1 0.2 0.7 -0.9 0.4 1.0 0.0 0.5 0.1
Ever had hysterectomy (womb removed) 0.2 0.2 0.6 0.8 -0.8 -0.2 -0.1 -0.2 0.7 0.2 -0.4
Systolic blood pressure, automated reading 0.8 2.4 6.1 -0.3 1.5 0.6 2.5 1.6 0.6 -1.8 1.9
Eye problems/disorders: Diabetes related eye disease 1.4 1.5 5.2 -0.7 -2.3 0.6 -0.4 -2.0 0.0 -1.3 0.4
Angina 0.2 0.3 0.9 -0.7 -0.5 0.3 0.3 0.0 -0.5 -0.9 0.5
Medication for hormone replacement therapy 0.9 1.0 1.9 -0.3 -1.3 -0.9 1.2 1.0 -0.4 -0.9 1.4
Vitamin and mineral supplements 0.9 1.2 4.6 1.9 0.1 0.9 0.3 0.2 2.1 0.4 0.2
Supplements: Zinc 1.1 1.2 3.5 -0.1 0.6 -1.5 0.7 0.1 0.5 -1.6 1.9
Medication: Co-codamol 0.9 1.0 3.5 1.2 -1.9 0.2 -0.1 -1.3 1.2 0.2 0.1
Medication: Metformin 0.5 0.8 1.9 -1.1 -0.2 0.9 -1.4 0.1 -1.1 0.2 -0.9
Diabetes (father) 0.6 0.7 2.7 1.1 -0.6 0.5 0.3 -0.2 1.7 -0.7 0.7
Diabetes (mother) 0.3 0.4 2.6 0.2 -0.5 -1.6 0.3 0.6 0.4 0.2 -0.2
Severe depression (siblings) 0.7 0.8 2.2 1.5 -0.5 0.6 1.2 0.9 1.0 0.3 0.2
Pack years adult smoking proportion 1.3 2.0 11.4 -0.2 -1.7 -0.9 0.3 -3.4 -0.3 -0.8 -0.5
Impedance of leg (right) 0.6 3.1 8.7 -0.1 1.2 -0.8 2.8 0.6 0.6 -2.3 2.9
Leg fat-free mass (left) 0.8 4.0 8.6 1.3 -2.2 1.6 -2.5 -1.1 0.5 2.6 -2.9
Trunk fat percentage 0.3 1.2 7.0 0.8 -2.7 0.4 0.2 -0.6 0.9 0.4 -0.4
Hand grip strength (right) 0.9 2.6 7.8 0.7 -1.3 0.8 -2.0 -0.1 -0.8 2.8 -2.3
Townsend deprivation index at recruitment 0.3 0.5 1.7 -0.0 0.7 0.7 -0.3 -1.3 0.6 -0.7 0.1
Current tobacco smoking 3.3 5.5 13.9 0.8 -1.3 -0.5 2.6 3.2 2.3 -2.1 3.7
Average weekly fortified wine intake 0.6 0.7 2.3 1.5 -0.6 0.3 -0.2 -0.3 1.0 1.4 -0.5
Maternal smoking around birth 1.6 2.4 4.5 0.9 1.1 0.7 1.9 1.6 1.8 -1.6 2.1
Fed-up feelings 0.3 0.5 2.2 -1.5 0.1 0.4 -0.8 -0.1 -0.8 -0.6 0.5
Frequency of unenthusiasm / disinterest in last 2 weeks 0.6 0.8 2.9 -0.7 -1.1 -0.6 -0.9 -1.7 0.2 -0.9 0.2
Relative age voice broke 0.5 0.7 1.7 0.2 -1.3 -0.6 0.7 -0.5 0.3 -1.2 1.1
Taking other prescription medications 0.2 0.3 0.9 0.2 0.7 -0.6 -0.7 -0.3 0.1 0.9 -0.4
Age when periods started (menarche) 1.3 3.1 5.2 1.6 -2.3 0.0 2.2 -1.0 2.3 -1.4 2.0
Bilateral oophorectomy (both ovaries removed) 0.2 0.2 0.5 0.7 0.3 -0.4 0.1 0.4 0.7 0.3 0.7
Heel bone mineral density (BMD) T-score, automated (left) 0.6 1.3 5.3 -1.8 -0.6 0.0 -0.5 0.5 -2.3 0.7 -0.5
Tinnitus: Yes, but not now, but have in the past 1.4 1.5 4.8 -0.3 2.2 -0.8 1.2 1.8 -0.6 -0.5 1.1
Qualifications: CSEs or equivalent 0.4 0.6 1.8 -0.8 -0.5 -0.2 -0.8 -0.5 -1.4 0.7 -0.7
Serious illness, injury or assault to yourself 1.4 1.7 4.3 1.0 0.6 -0.7 2.0 1.1 1.3 -0.7 2.1
High blood pressure 0.3 0.8 2.5 -0.1 1.6 1.5 0.6 0.7 0.6 -0.6 0.2
Hayfever, allergic rhinitis or eczema 0.3 0.7 2.9 -1.3 0.2 -1.7 -0.1 0.0 -1.0 -0.2 0.3
Multivitamins +/- minerals 1.7 2.1 7.0 -2.3 -0.3 -1.4 -1.3 -0.6 -2.7 -0.5 -0.5
Stomach or abdominal pain in last month 1.1 1.3 3.3 0.2 0.8 -1.8 1.5 1.1 0.8 -1.0 1.3
Supplements: Glucosamine 1.4 1.8 4.4 -0.7 -0.9 0.6 -1.2 -0.7 -1.9 1.6 -2.1
Diverticular disease/diverticulitis (self-reported) 0.2 0.3 1.1 -0.3 0.1 0.2 -0.1 0.4 -0.6 0.7 -1.1
Medication: Atenolol 0.6 0.7 2.5 -0.6 0.4 0.4 -0.5 1.6 -1.4 0.5 -0.6
Medication: Levothyroxine sodium 0.2 0.3 0.9 0.4 0.5 0.3 -0.6 0.9 -0.2 0.8 -0.6
Sitting height 0.9 6.1 12.1 0.8 -2.9 2.0 -3.2 -1.0 -1.0 3.5 -3.3
Chronic bronchitis/emphysema (father) 0.2 0.2 1.1 -1.0 -0.3 -0.3 -0.4 -0.3 -0.6 -0.1 -0.2
High blood pressure (mother) 0.6 0.8 2.9 -0.1 0.3 0.9 -0.9 -0.2 -0.8 1.0 -1.7
Body mass index (BMI) 0.2 1.1 4.9 0.9 -2.2 -0.1 -0.0 -1.2 1.1 -0.2 -0.4
Impedance of leg (left) 0.5 2.5 6.7 -0.6 0.9 -1.4 2.4 0.5 0.1 -2.1 2.6
Leg predicted mass (left) 0.8 4.2 8.9 1.2 -2.3 1.5 -2.5 -1.3 0.4 2.6 -3.0
Trunk fat mass 0.4 1.8 8.6 1.3 -2.9 0.7 -0.3 -0.7 1.0 1.1 -1.0
Waist circumference 0.4 1.4 5.8 0.3 -2.4 -0.0 -0.9 -2.0 0.3 0.1 -0.8
Number of incorrect matches in round 0.5 0.8 3.0 1.7 0.5 0.5 -0.2 -0.4 1.2 0.9 -0.7
Past tobacco smoking 1.4 2.6 12.7 -1.1 3.6 -1.4 0.2 2.0 -0.6 0.3 0.5
Alcohol usually taken with meals 0.3 0.5 1.1 1.0 0.8 -1.1 0.7 -0.1 0.7 0.5 -0.0
Nervous feelings 1.1 2.0 6.0 -1.3 2.5 0.1 -1.6 0.8 -1.5 1.3 -1.1
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.4 1.7 -0.1 1.3 -0.5 -0.7 -0.5 0.6 0.4 -0.4
Hearing difficulty/problems with background noise 0.2 0.4 1.9 0.1 -1.4 -0.8 0.1 -0.2 0.2 -0.5 -0.1
Hair/balding pattern: Pattern 2 0.6 0.8 1.7 1.2 0.5 1.3 1.0 0.2 1.3 0.1 0.1
Had menopause 1.2 1.5 3.6 -0.3 -1.6 -0.0 -1.6 -1.3 -0.8 0.9 -1.9
Had other major operations 0.8 1.0 2.9 0.8 1.0 0.6 -0.8 1.0 0.5 1.7 -1.0
Forced vital capacity (FVC) 0.3 1.3 2.9 -0.5 1.4 -0.7 -0.9 1.2 -1.3 1.7 -0.9
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.3 3.7 -1.2 -0.3 0.6 -1.0 0.4 -1.9 1.6 -1.1
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 2.6 0.3 -1.6 0.3 0.1 -0.4 0.5 -0.2 0.4
Qualifications: None of the above 0.2 0.4 0.9 0.3 0.6 0.4 0.7 -0.0 0.9 -1.0 0.8
Financial difficulties in last 2 years 2.1 2.9 5.6 -2.3 -2.4 -1.6 -0.6 -1.9 -2.1 -1.1 0.2
Mouth/teeth dental problems 1.5 2.3 7.9 -0.9 0.3 0.1 -2.8 -0.1 -1.4 1.7 -2.2
Heart attack 0.9 1.1 3.2 -1.2 1.0 -0.8 0.6 -0.1 -1.8 -1.0 1.0
Allergy 0.7 1.6 4.4 1.5 0.5 1.1 1.4 2.1 1.0 -0.3 1.2
Pain all over the body in last month 1.6 1.8 4.4 1.6 -1.8 0.6 -0.7 -2.1 1.5 0.7 -0.6
Diabetes (self-reported) 0.2 0.3 1.8 0.5 -0.2 1.4 -0.4 0.2 0.5 0.1 -0.5
Hayfever/allergic rhinitis (self-reported) 0.2 0.3 0.8 0.5 0.9 -0.5 -0.3 0.3 0.5 0.2 -0.6
Medication: Ramipril 1.1 1.4 7.5 0.4 2.7 1.1 0.3 1.3 0.2 0.6 -0.0
Medication: Simvastatin 0.2 0.3 2.0 -0.2 1.4 0.4 0.5 -0.3 0.0 -0.5 0.1
Fluid intelligence score 0.3 0.6 1.6 1.1 -0.0 0.4 1.3 0.6 1.0 -0.1 0.6
Illnesses of siblings 0.7 1.0 3.9 0.4 -2.0 1.1 -1.0 -0.1 0.2 0.9 -0.9
Neuroticism score 0.9 1.9 3.1 -0.9 1.5 1.7 -1.8 1.1 -1.2 1.5 -1.1
Weight 0.5 2.7 8.1 1.6 -2.9 0.8 -1.2 -1.2 1.1 1.6 -1.8
Impedance of arm (right) 0.2 1.1 3.9 -0.5 1.9 0.6 0.5 2.0 -0.2 0.2 0.7
Arm fat percentage (right) 0.1 0.6 2.5 0.8 -1.6 0.0 0.3 -0.0 1.2 -0.0 -0.1
Trunk fat-free mass 0.5 2.8 5.5 1.6 -2.4 0.8 -1.7 -1.2 0.8 2.2 -2.0
Hip circumference 0.5 2.0 4.7 2.2 -1.8 1.0 -0.5 -0.1 1.8 1.4 -1.2
Time employed in main current job 2.2 2.5 5.4 2.0 0.9 2.3 -0.8 0.9 1.1 2.3 -1.6
Alcohol intake versus 10 years previously 1.8 2.7 6.2 -1.5 2.5 -0.6 1.7 2.1 -1.2 -1.2 1.6
Father’s age at death 0.7 0.9 1.7 -1.1 -0.8 -1.3 -0.4 1.2 -1.3 0.2 0.2
Worrier / anxious feelings 1.3 2.5 4.6 -1.5 1.4 0.5 -2.1 1.0 -2.1 1.7 -1.6
Frequency of tiredness / lethargy in last 2 weeks 0.6 1.0 2.4 -1.4 -0.1 -0.9 -0.4 -1.0 -0.8 -1.6 0.8
Falls in the last year 0.3 0.4 1.5 -0.8 -1.2 -0.5 0.8 -0.6 -0.1 -0.3 0.2
Hair/balding pattern: Pattern 3 0.1 0.2 0.6 0.5 -0.8 0.0 -0.4 0.5 0.0 0.3 0.5
Number of live births 1.1 1.5 2.7 -1.0 -1.4 0.7 -1.4 -0.8 -1.6 1.1 -1.5
Forced expiratory volume in 1-second (FEV1) 0.3 1.1 4.6 -1.5 -0.1 -1.0 -0.4 0.8 -2.2 0.4 0.0
Pulse rate 0.1 0.2 0.5 0.5 0.7 0.5 0.1 0.4 0.5 0.7 -0.1
Happiness 1.6 1.9 3.9 -0.4 -1.9 2.0 -1.6 1.1 -1.2 1.2 -1.0
Noisy workplace 0.4 0.5 3.5 -0.2 -0.2 0.1 0.4 1.9 -0.5 0.1 0.3
Qualifications: A levels/AS levels or equivalent 0.4 1.0 3.2 0.1 1.3 -1.2 1.0 1.8 -0.0 0.1 0.6
Serious illness, injury or assault of a close relative in last 2 years 1.5 1.7 6.0 1.5 2.4 0.5 0.5 1.7 0.7 1.3 -0.5
Mouth/teeth dental problems: Dentures 1.3 2.2 5.4 1.1 0.2 -0.1 2.2 0.4 1.8 -1.7 2.3
Asthma 2.2 4.4 10.8 0.1 -0.7 1.9 -3.3 -2.0 -0.7 2.3 -3.2
Medication: Ibuprofen (e.g. Nurofen) 1.9 2.4 5.2 1.1 -0.6 1.0 -1.5 -1.9 0.6 2.3 -2.3
Medication: Cholesterol lowering 0.8 1.2 4.9 -0.3 2.2 0.8 0.6 1.7 -0.3 -0.2 0.6
Depression (self-reported) 0.3 0.4 0.9 -0.2 0.2 0.0 -0.5 -0.9 -0.5 0.8 -0.8
Medication: Lansoprazole 1.5 1.7 3.3 -0.6 1.4 -1.3 1.7 -0.1 0.5 -1.8 1.8
Prospective memory result 0.8 1.0 1.9 0.2 -0.6 -1.1 1.3 0.8 0.7 -1.1 1.4
Lung cancer (father) 0.5 0.6 2.2 -0.4 0.2 -0.6 -0.1 -1.4 0.0 -1.5 0.5
Illnesses of mother 0.1 0.2 0.9 -0.0 -0.4 -0.1 0.2 -0.5 -0.2 0.2 0.9
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.3 4.3 -1.9 0.1 -1.2 -0.3 0.7 -2.1 -0.0 0.2
Pulse wave Arterial Stiffness index 2.6 3.0 9.8 3.1 -0.7 0.5 0.5 1.3 2.9 1.5 -0.9
Impedance of arm (left) 0.3 1.2 3.1 -0.7 1.7 1.2 -0.2 1.8 -0.7 1.1 -0.4
Arm fat mass (right) 0.4 1.7 8.0 1.0 -2.8 0.3 -0.8 -1.2 0.9 0.6 -1.0
Trunk predicted mass 0.5 2.9 5.3 1.6 -2.3 0.8 -1.8 -1.2 0.8 2.3 -2.1
Standing height 0.5 5.1 15.1 1.9 -1.8 1.8 -2.5 -0.5 0.5 3.9 -3.0
Length of working week for main job 1.0 1.1 5.6 -0.5 -2.4 0.5 -0.7 -1.4 -0.2 -0.1 -0.6
Exposure to tobacco smoke at home 1.0 1.2 3.1 -0.0 -1.8 -0.4 1.1 -1.3 0.6 -1.1 1.3
Breastfed as a baby 1.2 1.5 3.4 1.9 0.1 -1.0 1.8 1.4 1.3 0.2 0.2
Tense / ‘highly strung’ 0.7 1.1 2.3 1.1 1.2 1.5 -0.3 1.1 1.3 1.0 0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.8 1.2 2.4 -0.9 -0.7 0.5 -1.5 -1.0 -1.5 1.2 -0.8
Hair/balding pattern: Pattern 4 0.0 0.1 0.3 0.0 0.6 -0.5 0.0 -0.2 -0.0 0.2 -0.6
Birth weight of first child 0.6 1.1 2.3 0.8 -1.2 -1.1 0.8 0.7 1.3 -0.5 1.5
Peak expiratory flow (PEF) 0.6 1.5 5.9 -0.6 -2.4 -1.1 -0.1 -1.2 -1.6 -0.2 0.5
Pulse wave reflection index 0.3 0.4 1.1 0.7 -0.9 -0.0 -0.2 0.2 1.0 0.3 -0.8
Ever highly irritable/argumentative for 2 days 1.7 2.0 4.3 -2.1 -1.6 -1.2 -1.2 -2.0 -1.5 -0.2 -0.4
Loud music exposure frequency 1.1 1.3 4.3 0.4 -0.0 0.3 -1.1 2.1 -0.5 1.9 -0.8
Qualifications: O levels/GCSEs or equivalent 0.4 0.7 2.4 -0.6 -0.2 -1.6 0.4 1.2 -0.7 0.6 0.1
Mouth/teeth dental problems: Bleeding gums 0.8 1.0 3.2 1.5 0.5 1.8 0.3 -0.2 1.5 0.3 -0.1
Blood clot in the leg (DVT) 0.8 1.0 2.7 -0.7 0.6 -0.2 -1.1 -1.1 -0.5 1.4 -1.6
Medication: Paracetamol 1.2 2.0 6.1 0.5 0.4 0.2 -1.9 -1.1 -0.4 2.1 -2.5
Headache pain in last month 1.5 2.6 5.0 -1.0 0.8 -1.5 -2.2 -0.9 -1.7 1.7 -2.2
Medication for cholesterol, blood pressure or diabetes 1.5 2.5 11.1 -0.1 -2.4 -1.4 -0.7 -3.3 0.1 -0.6 -0.3
Glaucoma (self-reported) 1.2 1.4 5.6 -0.5 2.1 -0.0 0.3 2.4 -0.6 0.1 0.5
Gout (self-reported) 1.4 2.0 8.6 -1.1 0.9 0.2 1.2 2.9 -1.0 -0.3 1.6
Hypothyroidism/myxoedema (self-reported) 0.3 0.6 1.3 -0.5 -0.5 0.4 -1.0 0.2 -1.1 0.7 -1.0
Medication: Amlodipine 0.4 0.5 1.8 -0.0 -1.3 1.0 -0.7 -0.5 -0.1 0.3 -0.9
Medication: Ventolin 100micrograms inhaler 0.7 0.9 3.1 -0.2 0.4 0.1 -1.0 -1.6 -0.2 0.5 -1.8
Birth weight 0.5 1.0 3.0 0.9 -1.7 -1.2 -0.0 0.2 0.1 1.5 -0.3
Chronic bronchitis/emphysema (mother) 0.2 0.3 0.8 -0.6 0.9 -0.1 -0.4 0.7 -0.3 -0.2 -0.3
High blood pressure (siblings) 0.8 1.2 4.2 -0.9 2.0 -1.3 0.9 0.5 -0.6 -0.9 0.7
Forced vital capacity (FVC), Best measure 0.4 1.3 2.7 -0.8 1.7 -1.0 -0.9 0.9 -1.3 1.4 -0.8
Body fat percentage 0.2 0.8 4.4 0.8 -2.1 0.2 0.5 -0.3 1.0 0.0 -0.1
Leg fat percentage (right) 0.3 1.2 3.1 1.4 -1.4 0.3 1.2 -0.5 1.8 -0.7 0.4
Arm fat-free mass (right) 0.7 3.7 8.2 1.7 -2.9 0.8 -1.9 -1.7 0.9 2.2 -2.4
Exposure to tobacco smoke outside home 0.8 1.0 2.2 -1.2 -1.5 -0.2 -1.4 -0.8 -1.3 0.3 -0.2
Comparative body size at age 10 1.4 3.8 9.6 -1.8 -1.4 -2.2 1.3 -1.8 -0.5 -3.1 2.3
Number of full brothers 1.3 1.6 5.5 2.3 0.2 1.1 1.0 0.4 2.1 0.1 0.4
Worry too long after embarrassment 0.7 1.1 2.3 -0.4 0.4 1.5 -0.5 1.4 -0.7 1.5 -1.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.2 1.0 -0.3 -0.3 -0.6 0.5 0.2 0.3 -0.0 1.0
Wheeze or whistling in the chest in last year 0.6 1.1 3.6 1.4 -1.0 0.5 0.2 -1.3 1.9 -0.4 0.2
Number of children fathered 0.8 0.9 3.6 -0.2 -1.9 -0.5 0.1 -1.5 0.1 -1.0 0.2
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.5 1.1 -0.6 0.6 0.8 -1.0 0.5 -0.9 0.5 -0.6
Age at first live birth 0.3 0.6 1.4 -1.1 1.2 -0.9 0.2 0.7 -1.0 -0.2 -0.0
Pulse wave peak to peak time 2.5 2.9 9.0 -3.0 0.7 -0.5 -0.7 -1.6 -2.8 -1.4 0.7
Health satisfaction 1.3 1.6 5.8 0.4 -1.2 2.4 -1.6 0.8 -0.1 1.1 -1.0
Shortness of breath walking on level ground 0.8 1.0 2.8 -0.6 -0.8 0.7 -1.1 -1.2 -0.9 0.3 -1.7
Qualifications: College or University degree 0.1 0.4 2.2 -0.2 1.5 -0.2 0.2 0.6 -0.2 0.4 -0.0
Eye problems/disorders: None of the above 0.4 0.4 1.2 0.8 -0.1 -0.3 -0.5 -1.1 1.0 0.1 -0.5
Mouth/teeth dental problems: Loose teeth 0.9 1.1 4.4 -0.5 -2.1 -0.4 0.9 0.3 -0.4 -0.9 1.5
Emphysema/chronic bronchitis 0.7 0.8 3.0 -0.2 -0.7 -0.6 -0.8 -1.7 -0.2 0.3 -1.2
Medication for pain relief, constipation, heartburn 0.7 1.2 3.0 -1.3 -1.0 -0.9 0.6 0.7 -0.7 -1.7 1.4
Neck or shoulder pain in last month 0.4 0.5 1.5 -0.8 0.2 -0.7 -0.1 -1.2 -1.1 -0.5 0.4
Medication: Blood pressure 1.5 2.7 12.4 0.6 2.1 1.4 0.9 3.5 0.4 1.0 -0.0
Angina (self-reported) 0.1 0.2 0.5 -0.5 -0.7 0.4 0.2 0.1 -0.5 -0.6 0.3
Migraine (self-reported) 0.3 0.4 0.9 -0.4 -0.6 -0.7 -0.5 -0.9 -0.8 0.4 -0.1
Medication: Ibuprofen 1.7 2.0 4.1 1.5 -0.3 0.9 -1.2 -1.8 1.2 2.0 -1.7
Medication: Allopurinol 1.3 1.8 6.4 -1.0 -0.1 0.2 1.4 2.5 -1.1 -0.7 1.8
Medication: Omeprazole 0.9 1.0 3.1 0.5 -0.2 -0.0 -1.4 -0.2 -0.1 1.7 -1.8
Medication: Seretide 50 evohaler 2.1 2.4 7.5 1.1 1.4 1.0 -1.3 0.4 -0.3 2.7 -2.4
Mean time to correctly identify matches 1.5 2.8 6.4 1.4 -0.2 -1.2 2.1 0.5 2.5 -1.7 2.3
Heart disease (mother) 0.5 0.6 1.7 0.8 1.3 0.3 -0.0 1.2 0.9 -0.1 0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 1.2 0.6 1.1 0.8 0.5 1.1 -0.1 0.4 -0.7
Whole body fat mass 0.3 1.4 6.5 1.1 -2.5 0.5 -0.4 -0.8 0.9 0.8 -0.9
Leg fat mass (right) 0.3 1.1 4.7 1.3 -2.2 0.4 -0.0 -0.8 1.3 0.3 -0.4
Arm predicted mass (right) 0.7 3.8 9.3 1.3 -3.0 0.7 -2.0 -2.1 0.5 2.1 -2.4
Pulse rate, automated reading 0.5 1.6 9.2 0.8 3.0 -0.0 0.5 1.2 0.8 0.8 0.2
Alcohol intake frequency. 1.1 2.5 6.2 -1.5 0.4 -2.5 1.1 -0.8 -0.5 -2.2 2.0
Comparative height size at age 10 0.3 1.6 5.6 1.0 -1.1 0.8 -1.5 -0.0 0.3 2.4 -1.5
Number of full sisters 0.8 1.0 3.5 1.9 0.1 -0.6 0.7 -0.0 1.9 -0.1 0.4
Suffer from ‘nerves’ 0.5 0.9 5.4 -0.6 2.3 0.7 -0.3 -0.0 0.1 -0.3 0.7
Overall health rating 0.2 0.5 2.6 -0.1 -1.6 0.3 -0.6 -0.8 -0.5 0.4 -0.1
Chest pain or discomfort 2.6 3.8 6.8 2.2 0.4 2.6 -2.4 -1.0 1.5 2.4 -1.9
Had major operations 0.6 0.7 1.6 1.2 1.3 0.3 -0.1 0.2 1.3 0.7 -0.1
Age at last live birth 0.5 0.8 1.3 -0.8 -0.6 -1.1 1.0 0.5 -0.8 -1.0 0.9
Family relationship satisfaction 2.6 3.2 6.8 2.5 0.8 2.4 0.7 2.6 1.9 1.4 0.3
Leg pain on walking 1.7 2.1 6.6 1.6 -1.4 1.7 0.6 -1.3 2.6 -0.6 0.4
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.3 1.1 -0.6 -0.2 -0.6 -0.6 -0.4 -1.0 0.4 -0.3
Commuting to job workplace: Car/motor vehicle 0.4 0.4 1.2 -0.2 -1.1 0.3 0.8 0.2 -0.4 -1.0 0.6
Illness, injury, bereavement, stress in last 2 years 1.3 1.6 3.3 1.8 1.3 0.6 -0.4 1.5 1.7 1.2 -0.7
Medication: Aspirin 2.0 2.6 6.7 1.4 2.4 0.5 2.6 0.5 2.0 -1.0 1.0
Supplements: Vitamin C 0.5 0.6 2.4 0.9 -0.4 1.5 0.0 0.3 1.1 0.1 0.1
Knee pain experienced in last month 0.5 0.8 3.2 0.3 -0.9 0.4 -0.7 -1.8 0.3 0.6 -0.8
Hypertension (Self-reported) 0.3 0.9 3.1 -0.0 1.8 1.6 0.7 0.6 0.7 -0.5 0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.9 3.4 5.9 -2.0 -1.4 -0.7 -2.1 -2.0 -2.4 0.7 -2.4
Illnesses of father: Heart disease 0.3 0.4 1.2 -0.6 -1.1 -0.0 -0.4 -0.2 -0.7 -0.8 0.5
Illnesses of siblings: Diabetes 2.7 3.3 7.9 1.5 1.3 -1.4 2.8 0.3 2.3 -1.5 2.1
Smoking status: Previous 1.4 2.1 7.1 0.9 -2.6 1.2 -0.3 -2.7 0.2 -0.2 -0.6
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.3 3.4 0.2 0.4 1.9 -0.8 0.6 -0.3 1.5 -1.7
Whole body fat-free mass 0.6 3.6 6.5 1.5 -2.5 1.1 -2.2 -1.3 0.7 2.5 -2.5
Leg fat-free mass (right) 0.8 4.5 10.9 0.9 -2.1 1.4 -2.9 -1.1 0.1 2.9 -3.3
Arm fat percentage (left) 0.2 0.6 3.2 0.5 -1.8 0.3 -0.3 -0.4 0.6 0.5 -0.8
Average weekly red wine intake 1.7 2.5 5.1 2.3 0.2 1.4 -1.1 -1.0 1.5 2.0 -2.0
Handedness (chirality/laterality): Left-handed 0.3 0.3 0.9 -0.0 0.4 -0.1 0.3 0.9 0.1 -0.8 0.9
Mood swings 0.6 1.1 2.0 -1.2 1.2 0.6 -1.4 0.9 -1.2 0.8 -0.8
Loneliness, isolation 0.7 0.9 2.5 0.6 -0.2 0.7 -1.6 -1.5 0.8 0.7 -0.8
Long-standing illness, disability or infirmity 0.5 0.7 2.9 -0.1 -1.7 -0.7 -0.1 -1.6 -0.2 -0.2 0.1
Ever had bowel cancer screening 0.3 0.4 1.3 -0.2 0.5 0.5 -0.1 -1.1 -0.1 0.1 -1.0
Diabetes diagnosed by doctor 0.1 0.2 0.4 0.2 -0.6 0.5 0.3 -0.3 0.6 -0.7 0.3
Ever had stillbirth, spontaneous miscarriage or termination 1.3 1.3 3.0 -1.2 -1.0 -0.3 -1.7 -1.7 -1.2 0.6 -0.9
Friendships satisfaction 0.4 0.4 1.4 -0.0 -0.1 1.1 0.3 1.2 0.0 -0.4 0.8
Qualifications: nursing, teaching 0.5 0.8 2.4 -1.1 0.3 -0.9 0.1 1.1 -1.5 0.4 -0.7
Commuting to job workplace: Walk 2.2 2.4 5.0 -1.1 1.8 -2.2 1.3 0.6 0.1 -1.7 2.1
Eye problems/disorders: Cataract 0.4 0.5 1.3 -1.0 -0.3 0.4 -0.2 -1.1 -1.1 -0.2 -0.0
Mouth/teeth dental problems: Mouth ulcers 1.7 2.8 6.4 -1.3 -1.2 -1.6 2.0 -0.3 -0.6 -2.4 2.5
Medication for cholesterol 0.6 0.9 4.0 1.2 -0.1 -0.1 0.6 2.0 0.9 0.8 0.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 1.4 1.6 5.4 -0.7 -1.8 -0.5 0.6 -2.3 -0.2 -1.5 0.9
Back pain experienced in last month 0.6 0.9 1.8 0.7 0.3 -0.2 -1.3 -1.1 0.5 1.3 -1.3
Mineral and other dietary supplements 0.2 0.2 1.0 0.2 1.0 0.1 0.1 -0.3 0.7 -0.2 0.4
Breast cancer (self-reported) 0.5 0.6 1.7 1.2 0.3 0.9 0.5 -0.6 1.3 -0.3 0.5
Asthma (self-reported) 2.2 4.3 10.5 0.2 -0.9 1.8 -3.2 -2.0 -0.5 2.4 -3.2
Osteoporosis (self-reported) 0.9 1.1 3.3 0.8 0.6 1.0 -0.5 1.5 0.4 1.8 -0.9
Osteoarthritis (self-reported) 1.4 1.9 4.0 2.0 0.7 1.6 1.2 1.4 2.0 -0.0 0.7
Medication: Aspirin 2.2 2.8 8.2 1.4 2.9 0.6 2.4 0.5 2.1 -0.9 0.9
Medication: Gliclazide 0.6 0.7 2.2 0.5 1.5 0.6 -0.1 1.0 -0.1 1.0 -0.8
Illnesses of father: None of the above (group 1) 0.1 0.1 0.1 0.3 0.4 0.2 0.1 -0.1 0.4 0.3 -0.1
Smoking status: Current 2.4 3.9 9.1 0.6 -1.7 -0.2 2.1 2.7 2.0 -1.8 3.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.9 1.9 6.1 -0.8 1.3 -1.3 1.2 2.5 -0.4 -1.2 1.4
Whole body water mass 0.7 3.8 6.9 1.5 -2.6 1.1 -2.2 -1.2 0.7 2.5 -2.6
Leg predicted mass (right) 0.8 4.3 10.4 1.0 -2.0 1.4 -2.7 -1.1 0.1 2.8 -3.2
Arm fat mass (left) 0.4 1.8 7.6 1.1 -2.8 0.3 -0.8 -1.2 1.0 0.9 -1.2
Number of self-reported non-cancer illnesses 0.7 1.1 3.1 0.5 0.2 1.8 -1.3 -0.8 0.5 0.9 -1.5
Average weekly champagne plus white wine intake 0.6 0.9 3.0 -0.6 -1.2 -1.3 -0.2 -1.7 -0.4 -0.5 0.5
Miserableness 0.3 0.5 1.3 -1.0 -0.0 -0.4 -1.1 -0.5 -0.7 0.4 -0.5
Guilty feelings 0.6 0.9 2.3 0.1 -0.2 1.2 -1.1 0.2 -0.2 1.5 -1.4
Wears glasses or contact lenses 1.6 1.9 5.1 1.1 0.0 1.0 -1.7 0.8 0.0 2.2 -2.1
Ever taken oral contraceptive pill 0.8 0.8 4.4 -0.7 -2.1 -0.7 0.1 0.7 -0.7 -0.5 0.2
Hearing aid user 0.4 0.5 1.4 -0.7 0.7 -0.2 1.2 0.2 -0.4 -0.7 0.9
Mother’s age at death 0.5 0.6 1.9 0.7 0.8 0.6 0.1 0.3 0.2 1.4 -1.2
Financial situation satisfaction 2.3 2.9 6.9 -1.6 -1.1 1.2 -2.6 -0.7 -2.2 1.3 -1.9
Tinnitus: Yes, now most or all of the time 0.8 1.0 3.6 -1.2 0.1 -1.9 0.2 -0.5 -1.1 -1.1 0.4
Commuting to job workplace: Public transport 1.0 1.1 2.1 -1.2 1.5 -0.1 -1.3 1.0 -1.4 0.8 -0.5
Eye problems/disorders: Glaucoma 1.5 1.8 5.9 -0.8 2.4 0.4 -0.7 2.2 -1.2 0.7 -0.5
Medication: Blood pressure 0.6 1.0 2.6 -1.1 0.5 0.5 -1.4 -1.6 -1.0 -0.5 -0.9
Pain type(s) experienced in last month: Hip pain 0.6 0.7 1.2 0.7 -0.8 0.9 -1.1 -0.5 0.9 0.8 -1.0
Supplements: Fish oil (including cod liver oil) 0.3 0.4 0.8 -0.3 -0.8 -0.8 0.4 0.3 -0.2 -0.7 0.9
High cholesterol (Self-reported) 0.3 0.5 1.5 0.3 0.5 1.2 -0.6 -1.0 0.9 -0.6 -0.2
Medication: Bendroflumethiazide 0.7 1.1 3.3 -1.8 1.3 -0.9 -0.1 0.7 -1.3 -0.7 0.0
Medication: Paracetamol 1.0 1.6 4.1 0.6 -0.1 0.2 -1.4 -1.4 -0.3 1.9 -2.0
Medication: Lisinopril 0.3 0.4 1.2 -0.5 -0.1 -0.7 0.4 0.8 -0.1 -1.1 0.9
Medication: Atorvastatin 0.9 1.2 4.0 -1.0 0.5 -0.9 1.0 0.6 -0.0 -2.0 1.3
Illnesses of father: High blood pressure 1.0 1.2 5.1 1.1 2.3 0.6 0.7 0.8 1.2 -0.4 0.6
Alcohol drinker status: Never 0.4 0.5 1.5 -0.1 1.1 0.4 -0.7 1.2 0.3 0.1 0.2
Ever smoked 1.3 2.4 11.3 0.6 -3.4 1.2 -0.4 -2.2 0.6 -0.5 -0.3
Basal metabolic rate 0.6 3.3 6.6 1.4 -2.6 1.0 -2.0 -1.3 0.7 2.2 -2.4
Leg fat percentage (left) 0.3 1.0 2.7 1.2 -1.6 0.0 1.0 -0.4 1.6 -0.5 0.3
Arm fat-free mass (left) 0.7 3.3 7.9 2.0 -2.8 0.8 -1.5 -1.4 1.2 2.0 -2.1
Number of operations (self-reported) 0.2 0.3 0.9 0.4 0.6 -0.2 -0.5 0.1 0.7 0.8 -0.9
Average weekly beer plus cider intake 0.6 0.9 3.7 -0.4 -0.3 0.6 0.9 1.9 -0.0 -0.7 1.3
Irritability 0.6 1.0 3.3 0.0 1.2 1.3 0.5 1.8 0.5 0.1 0.8
Risk taking 0.9 1.3 2.8 1.1 -0.9 1.0 -1.1 -0.7 0.5 1.7 -1.5
Ever had prostate specific antigen (PSA) test 1.0 1.1 3.2 0.6 -1.0 0.3 1.0 1.1 0.8 -1.4 1.8
Fractured/broken bones in last 5 years 0.4 0.5 1.4 -1.2 -0.8 0.2 -0.4 -1.0 -0.7 -0.2 0.0
Age started oral contraceptive pill 1.2 1.5 2.9 0.5 1.7 1.2 -1.7 -0.4 0.6 1.3 -1.6
Diastolic blood pressure, automated reading 0.8 2.6 10.4 -2.4 3.2 0.6 -0.1 0.7 -1.9 -0.6 0.2
Ever depressed for a whole week 1.0 1.2 7.8 -0.4 -2.8 0.3 0.2 -0.7 -1.0 0.4 -0.2
Unable to work because of sickness or disability 1.4 1.9 4.5 -0.2 -1.8 -2.1 0.8 -2.1 0.4 -1.3 0.8
Commuting to job workplace: Cycle 0.8 0.9 2.7 -0.1 0.3 -0.4 -1.5 -0.8 -0.3 1.6 -1.3
Myopia 1.3 1.9 4.2 -1.4 -0.9 -1.1 -1.6 -1.3 -2.0 0.8 -1.3
Vascular/heart problems diagnosed by doctor 0.3 0.7 2.0 0.9 -1.4 -0.7 -0.8 -0.1 0.3 1.2 -0.5
Cholesterol lowering medication 1.4 2.1 8.7 -1.7 -0.0 -1.0 -0.2 -2.9 -0.5 -2.0 0.1
Medication: Omeprazole (e.g. Zanprol) 1.0 1.2 3.0 0.2 -1.1 -0.1 -1.7 -0.9 -0.4 1.2 -1.7
Pain experienced in last month 3.3 5.4 13.5 -0.4 -0.3 -0.9 3.7 2.9 0.3 -2.9 3.5
Supplements: Calcium 0.6 0.6 2.0 -0.5 0.1 0.3 -1.0 0.3 -1.4 0.6 -1.0
Basal cell carcinoma (self-reported) 0.2 0.2 0.6 0.4 0.3 0.4 0.4 0.8 0.2 0.5 0.4
Heart attack/myocardial infarction (self-reported) 0.9 1.1 3.0 -1.1 1.1 -0.8 0.7 0.0 -1.7 -1.1 1.2
Deep venous thrombosis (DVT) (self-reported) 0.7 0.9 2.4 -0.4 0.4 -0.2 -0.8 -1.1 -0.4 1.4 -1.5
Heart disease (siblings) 0.8 1.0 6.0 -0.7 2.4 -0.1 0.5 0.7 -1.0 -0.2 -0.0
Alcohol drinker status: Previous 0.6 0.7 2.0 0.1 -1.4 0.3 -0.9 -0.1 -0.7 0.9 -1.0
Pack years of smoking 1.3 2.0 10.3 -0.1 -1.6 -1.1 0.5 -3.2 -0.1 -1.0 -0.2
Impedance of whole body 0.2 1.0 2.2 -0.6 1.5 -0.0 1.3 1.2 -0.3 -0.6 1.3
Leg fat mass (left) 0.3 1.2 5.2 1.3 -2.3 0.3 -0.2 -0.7 1.3 0.5 -0.6
Arm predicted mass (left) 0.5 2.6 8.0 1.5 -2.8 0.3 -1.4 -1.5 0.8 1.6 -1.8