[Hub]/) : Traits : Irritable Bowel Disease (IBD) : ← →

chr1:160,559,549-162,630,958

Best TWAS P=3.65e-14 · Best GWAS P=1.95e-20 conditioned to 1.2e-08

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Testis ATF6 0.23 0.08 lasso 6 0.05 3.3e-03 9.3 -7.2 4.2e-13 -0.85 0.00 0.97 FALSE
2 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ITLN1 0.04 0.04 lasso 1 0.03 2.6e-04 -5.1 5.1 2.8e-07 0.01 0.02 0.88 FALSE
3 The Cancer Genome Atlas Brain Lower Grade Glioma CD244 0.05 0.05 lasso 2 0.05 3.2e-06 -5.2 -5.2 2.1e-07 -0.03 0.07 0.93 FALSE
4 The Cancer Genome Atlas Lung Adenocarcinoma CD244 0.03 0.00 blup 59 0.02 5.7e-04 -4.8 -5.1 2.7e-07 -0.03 0.07 0.82 FALSE
5 The Cancer Genome Atlas Lung Adenocarcinoma ITLN1 0.04 0.04 lasso 2 0.04 1.5e-05 -5.6 5.4 6.4e-08 0.01 0.01 0.98 FALSE
6 The Cancer Genome Atlas Pancreatic Adenocarcinoma FCGR2A 0.17 0.08 enet 5 0.16 2.3e-07 7.5 -7.6 3.7e-14 -0.64 0.05 0.87 TRUE
7 The Cancer Genome Atlas Pancreatic Adenocarcinoma FCGR3A 0.08 0.02 blup 18 0.03 3.0e-02 3.7 -5.4 6.6e-08 -0.42 0.01 0.23 FALSE
8 The Cancer Genome Atlas Thyroid Carcinoma CD244 0.03 0.03 lasso 2 0.03 3.2e-04 -5.2 -5.4 7.3e-08 -0.01 0.04 0.79 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma ITLN1 0.05 0.03 enet 3 0.03 4.4e-04 -4.8 5.6 2.8e-08 -0.01 0.01 0.86 FALSE
10 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma ITLN1 0.13 0.13 lasso 1 0.13 2.2e-04 -5.7 5.7 1.1e-08 0.01 0.01 0.91 TRUE