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chr9:97,966,874-100,366,953

Best TWAS P=7.16e-09 · Best GWAS P=2.02e-08 conditioned to 0.865

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	LOC441454	0.05	0.01	lasso	3	0.02	1.5e-03	4.5	5.3	1.2e-07	0.63	0.03	0.71	FALSE
2	GTEx	Breast Mammary Tissue	CDC14B	0.16	0.02	enet	21	0.02	3.7e-02	5.3	-5.5	4.6e-08	-0.86	0.02	0.95	FALSE
3	GTEx	Cells EBV-transformed lymphocytes	AAED1	0.17	0.02	lasso	3	0.04	2.4e-02	5.4	5.8	7.2e-09	0.93	0.04	0.61	TRUE
4	GTEx	Nerve Tibial	HSD17B3	0.14	0.00	enet	20	0.00	2.4e-01	5.2	5.4	7.6e-08	0.67	0.04	0.70	FALSE
5	GTEx	Testis	HABP4	0.19	0.22	lasso	9	0.21	1.1e-09	5.4	5.4	5.4e-08	1.00	0.02	0.98	FALSE
6	The Cancer Genome Atlas	Breast Invasive Carcinoma	CDC14B	0.02	0.01	lasso	1	0.01	3.0e-03	5.5	-5.5	4.9e-08	-1.00	0.01	0.77	FALSE
7	The Cancer Genome Atlas	Glioblastoma Multiforme	CDC14B	0.16	0.17	blup	41	0.19	2.6e-06	5.4	-5.5	2.9e-08	-0.97	0.02	0.97	FALSE
8	The Cancer Genome Atlas	Glioblastoma Multiforme	HABP4	0.08	0.06	blup	44	0.05	1.6e-02	5.1	-5.3	1.3e-07	-0.97	0.02	0.55	FALSE
9	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	HABP4	0.02	0.02	blup	44	0.02	7.1e-03	5.4	5.6	2.7e-08	0.99	0.02	0.79	FALSE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CDC14B	0.03	0.02	blup	42	0.02	2.1e-03	5.4	-5.6	1.9e-08	-0.96	0.02	0.82	FALSE
11	The Cancer Genome Atlas	Brain Lower Grade Glioma	CDC14B	0.05	0.06	lasso	5	0.06	6.5e-07	5.5	-5.4	7.5e-08	-0.97	0.02	0.98	FALSE
12	The Cancer Genome Atlas	Brain Lower Grade Glioma	HABP4	0.05	0.08	lasso	5	0.08	6.9e-09	5.2	-5.3	9.3e-08	-0.98	0.04	0.96	FALSE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	PTCH1	0.02	0.01	blup	54	0.02	1.1e-03	5.4	-5.2	2.3e-07	-0.03	0.01	0.77	TRUE
14	The Cancer Genome Atlas	Thyroid Carcinoma	CDC14B	0.05	0.07	blup	42	0.08	4.8e-08	5.6	-5.5	2.9e-08	-0.98	0.02	0.98	FALSE