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chr11:94,805,896-96,276,010

Best TWAS P=8.12e-09 · Best GWAS P=1.23e-08 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FAM76B	0.06	0.02	lasso	3	0.01	8.1e-03	5.4	-5.4	7.5e-08	-0.95	0.02	0.97	FALSE
2	GTEx	Adipose Subcutaneous	CEP57	0.17	0.12	enet	26	0.14	3.1e-11	5.6	5.7	1.4e-08	0.93	0.02	0.98	FALSE
3	GTEx	Brain Cerebellar Hemisphere	AP001877.1	0.29	0.24	lasso	7	0.25	5.0e-07	5.2	5.3	1.1e-07	0.96	0.02	0.97	FALSE
4	GTEx	Colon Transverse	CEP57	0.12	0.11	lasso	3	0.11	6.8e-06	5.4	5.5	4.5e-08	0.96	0.04	0.95	FALSE
5	GTEx	Esophagus Mucosa	CEP57	0.14	0.14	lasso	3	0.10	6.0e-07	5.4	5.5	3.9e-08	0.93	0.03	0.97	FALSE
6	GTEx	Lung	CEP57	0.12	0.05	enet	16	0.04	4.4e-04	5.2	5.5	3.7e-08	0.94	0.02	0.98	FALSE
7	GTEx	Muscle Skeletal	CEP57	0.15	0.18	lasso	9	0.18	1.8e-17	5.6	5.7	1.5e-08	0.99	0.02	0.98	FALSE
8	GTEx	Muscle Skeletal	AP001877.1	0.10	0.01	enet	26	0.03	8.9e-04	5.4	5.7	1.6e-08	0.72	0.05	0.94	FALSE
9	GTEx	Nerve Tibial	MTMR2	0.14	0.10	enet	16	0.08	2.0e-06	5.2	-5.8	8.1e-09	-0.97	0.02	0.98	TRUE
10	GTEx	Nerve Tibial	CEP57	0.15	0.08	lasso	6	0.07	1.9e-05	5.4	5.5	2.9e-08	0.96	0.02	0.98	FALSE
11	GTEx	Nerve Tibial	AP001877.1	0.15	0.05	lasso	3	0.05	1.6e-04	5.6	5.5	4.6e-08	0.96	0.02	0.98	FALSE
12	GTEx	Pancreas	CEP57	0.19	0.10	lasso	13	0.08	3.6e-04	5.3	5.5	4.1e-08	0.96	0.02	0.97	FALSE
13	GTEx	Skin Sun Exposed Lower leg	CEP57	0.19	0.14	enet	24	0.16	4.1e-13	5.4	5.3	9.0e-08	0.94	0.03	0.97	FALSE
14	GTEx	Thyroid	CEP57	0.11	0.01	enet	15	0.03	1.8e-03	5.4	5.6	1.6e-08	0.76	0.04	0.92	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	AP001877.1	0.17	0.27	lasso	12	0.27	3.6e-35	5.6	5.6	2.2e-08	1.00	0.02	0.98	FALSE
16	YFS	Blood	FAM76B	0.14	0.25	lasso	10	0.26	8.1e-83	5.7	-5.6	2.2e-08	-1.00	0.02	0.98	FALSE
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CEP57	0.02	0.00	blup	53	0.01	6.0e-02	5.4	5.4	5.6e-08	0.94	0.02	0.59	FALSE