[Hub]/) : Traits : Intelligence (Savage-Jansen 2018) :

chr11:94,805,896-96,276,010

Best TWAS P=8.12e-09 · Best GWAS P=1.23e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FAM76B 0.06 0.02 lasso 3 0.01 8.1e-03 5.4 -5.4 7.5e-08 -0.95 0.02 0.97 FALSE
2 GTEx Adipose Subcutaneous CEP57 0.17 0.12 enet 26 0.14 3.1e-11 5.6 5.7 1.4e-08 0.93 0.02 0.98 FALSE
3 GTEx Brain Cerebellar Hemisphere AP001877.1 0.29 0.24 lasso 7 0.25 5.0e-07 5.2 5.3 1.1e-07 0.96 0.02 0.97 FALSE
4 GTEx Colon Transverse CEP57 0.12 0.11 lasso 3 0.11 6.8e-06 5.4 5.5 4.5e-08 0.96 0.04 0.95 FALSE
5 GTEx Esophagus Mucosa CEP57 0.14 0.14 lasso 3 0.10 6.0e-07 5.4 5.5 3.9e-08 0.93 0.03 0.97 FALSE
6 GTEx Lung CEP57 0.12 0.05 enet 16 0.04 4.4e-04 5.2 5.5 3.7e-08 0.94 0.02 0.98 FALSE
7 GTEx Muscle Skeletal CEP57 0.15 0.18 lasso 9 0.18 1.8e-17 5.6 5.7 1.5e-08 0.99 0.02 0.98 FALSE
8 GTEx Muscle Skeletal AP001877.1 0.10 0.01 enet 26 0.03 8.9e-04 5.4 5.7 1.6e-08 0.72 0.05 0.94 FALSE
9 GTEx Nerve Tibial MTMR2 0.14 0.10 enet 16 0.08 2.0e-06 5.2 -5.8 8.1e-09 -0.97 0.02 0.98 TRUE
10 GTEx Nerve Tibial CEP57 0.15 0.08 lasso 6 0.07 1.9e-05 5.4 5.5 2.9e-08 0.96 0.02 0.98 FALSE
11 GTEx Nerve Tibial AP001877.1 0.15 0.05 lasso 3 0.05 1.6e-04 5.6 5.5 4.6e-08 0.96 0.02 0.98 FALSE
12 GTEx Pancreas CEP57 0.19 0.10 lasso 13 0.08 3.6e-04 5.3 5.5 4.1e-08 0.96 0.02 0.97 FALSE
13 GTEx Skin Sun Exposed Lower leg CEP57 0.19 0.14 enet 24 0.16 4.1e-13 5.4 5.3 9.0e-08 0.94 0.03 0.97 FALSE
14 GTEx Thyroid CEP57 0.11 0.01 enet 15 0.03 1.8e-03 5.4 5.6 1.6e-08 0.76 0.04 0.92 FALSE
15 ROSMAP Brain Pre-frontal Cortex AP001877.1 0.17 0.27 lasso 12 0.27 3.6e-35 5.6 5.6 2.2e-08 1.00 0.02 0.98 FALSE
16 YFS Blood FAM76B 0.14 0.25 lasso 10 0.26 8.1e-83 5.7 -5.6 2.2e-08 -1.00 0.02 0.98 FALSE
17 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CEP57 0.02 0.00 blup 53 0.01 6.0e-02 5.4 5.4 5.6e-08 0.94 0.02 0.59 FALSE