Best TWAS P=9.55e-08 · Best GWAS P=3.9e-07 conditioned to 0.0371
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | DYNLL1 | 0.06 | 0.01 | blup | 413 | 0.05 | 2.1e-06 | 3.5 | -5.3 | 1.3e-07 | 0.58 | 0.03 | 0.79 | FALSE |
2 | GTEx | Cells EBV-transformed lymphocytes | C12orf43 | 0.32 | -0.01 | enet | 46 | 0.04 | 1.5e-02 | -3.7 | 5.1 | 2.9e-07 | -0.57 | 0.02 | 0.30 | FALSE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | RNF10 | 0.04 | 0.01 | lasso | 6 | 0.02 | 5.9e-03 | 3.5 | -5.3 | 9.6e-08 | 0.66 | 0.01 | 0.47 | TRUE |