Best TWAS P=2.85e-08 · Best GWAS P=5.68e-11 conditioned to 6.13e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | DMXL2 | 0.06 | 0.06 | lasso | 3 | 0.05 | 5.9e-05 | 5.5 | -5.5 | 3.4e-08 | -0.29 | 0.60 | 0.24 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | SCG3 | 0.06 | 0.02 | blup | 67 | 0.03 | 5.3e-04 | 5.5 | -5.6 | 2.9e-08 | -0.33 | 0.13 | 0.69 | TRUE |