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chr16:71,070,698-72,657,531

Best TWAS P=2.56e-10 · Best GWAS P=3.79e-09 conditioned to 0.17

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Breast Mammary Tissue PHLPP2 0.31 0.13 lasso 5 0.15 2.6e-08 -5.1 -5.1 3.0e-07 0.66 0.61 0.39 FALSE
2 GTEx Breast Mammary Tissue (Female) PHLPP2 0.09 0.05 lasso 1 0.04 3.0e-02 -5.1 -5.1 2.8e-07 0.66 0.24 0.14 FALSE
3 GTEx Heart Atrial Appendage PHLPP2 0.14 0.17 lasso 5 0.14 4.7e-07 -5.4 -5.3 1.1e-07 0.67 0.35 0.64 FALSE
4 GTEx Muscle Skeletal IST1 0.09 0.05 lasso 4 0.08 4.2e-08 2.8 -5.2 2.4e-07 0.78 0.05 0.94 FALSE
5 GTEx Spleen PHLPP2 0.18 0.11 lasso 13 0.09 2.2e-03 -4.4 -5.2 1.5e-07 0.80 0.05 0.71 FALSE
6 GTEx Thyroid IST1 0.06 0.03 lasso 6 0.03 4.6e-03 -5.7 -5.8 5.0e-09 0.93 0.02 0.95 FALSE
7 GTEx Thyroid RP11-432I5.6 0.07 0.07 enet 11 0.05 1.2e-04 -5.1 -5.2 2.6e-07 0.64 0.42 0.44 FALSE
8 METSIM Adipose PHLPP2 0.07 0.03 lasso 5 0.06 1.7e-09 -5.4 -5.8 4.8e-09 0.68 0.56 0.44 FALSE
9 YFS Blood ATXN1L 0.02 0.02 blup 413 0.02 6.5e-07 -5.8 -6.3 2.6e-10 0.80 0.02 0.98 TRUE
10 The Cancer Genome Atlas Testicular Germ Cell Tumors PHLPP2 0.11 0.03 lasso 6 0.01 1.2e-01 -5.3 -5.5 4.1e-08 0.69 0.01 0.64 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma MARVELD3 0.08 0.01 blup 44 0.06 7.1e-07 3.3 -5.4 7.8e-08 0.72 0.04 0.86 FALSE