TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
LDL Cholesterol
:
←
→
chr6:160,293,151-161,336,020
Best TWAS P=6.37e-08 · Best GWAS P=1.7e-17 conditioned to 1.2e-12
160.4M
160.6M
160.8M
161M
161.2M
0
5
10
15
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Prostate Adenocarcinoma
LPA
0.09
0.04
blup
61
0.03
0.00023
4.0
-5.4
6.4e-08
-0.03
0.04
0.70
TRUE
1
The Cancer Genome Atlas
Head and Neck Squamous Cell Carcinoma
SLC22A1
0.03
0.00
blup
82
0.01
0.02450
-4.3
-5.4
6.7e-08
-0.29
0.02
0.14
TRUE