[Hub]/) : Traits : LDL Cholesterol : ← →

chr6:115,569,351-117,264,735

Best TWAS P=2.19e-09 · Best GWAS P=2.95e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells EBV-transformed lymphocytes FRK 0.12 0.07 enet 12 0.09 8.1e-04 4.5 5.4 6.4e-08 -0.87 0.04 0.89 FALSE
2 GTEx Cells Transformed fibroblasts FRK 0.12 0.18 lasso 5 0.16 8.0e-12 -5.9 6.0 2.2e-09 -1.00 0.01 0.99 TRUE
3 GTEx Colon Transverse FRK 0.14 0.16 lasso 4 0.14 5.7e-07 -5.9 5.7 1.1e-08 -0.99 0.01 0.99 FALSE
4 GTEx Esophagus Mucosa NT5DC1 0.09 0.08 lasso 2 0.05 2.9e-04 -5.9 5.9 3.6e-09 -1.00 0.01 0.98 FALSE
5 GTEx Muscle Skeletal NT5DC1 0.16 0.17 lasso 10 0.17 1.1e-16 -5.9 5.7 1.4e-08 -0.95 0.01 0.99 FALSE
6 GTEx Muscle Skeletal RP3-486I3.5 0.08 0.04 enet 12 0.03 2.8e-04 -5.9 5.5 4.1e-08 -0.91 0.01 0.99 FALSE
7 GTEx Nerve Tibial NT5DC1 0.16 0.12 lasso 4 0.13 2.1e-09 -5.8 5.4 6.9e-08 -0.93 0.01 0.99 FALSE
8 GTEx Pancreas FRK 0.09 0.13 lasso 5 0.09 1.2e-04 -5.9 5.9 3.4e-09 -1.00 0.01 0.98 FALSE
9 GTEx Thyroid FRK 0.08 0.10 lasso 3 0.09 4.6e-07 -5.9 5.9 4.6e-09 -0.99 0.01 0.99 FALSE
10 METSIM Adipose NT5DC1 0.11 0.08 lasso 8 0.09 8.2e-14 -5.8 5.7 9.0e-09 -0.98 0.01 0.99 FALSE
11 The Cancer Genome Atlas Colon Adenocarcinoma FRK 0.10 0.10 lasso 7 0.09 4.2e-06 -5.9 5.4 5.8e-08 -0.96 0.01 0.99 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma FRK 0.10 0.08 lasso 1 0.05 3.2e-06 -5.9 5.9 3.3e-09 -1.00 0.01 0.99 FALSE
13 The Cancer Genome Atlas Stomach Adenocarcinoma FRK 0.03 0.00 blup 94 0.03 4.6e-03 -5.9 5.7 1.2e-08 -0.88 0.02 0.83 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma FRK 0.08 0.09 lasso 2 0.09 5.0e-09 -5.9 5.9 3.8e-09 -1.00 0.01 0.99 FALSE