[Hub]/) : Traits : LDL Cholesterol : ← →

chr6:115,569,351-117,264,735

Best TWAS P=2.19e-09 · Best GWAS P=2.95e-09 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Cells Transformed fibroblasts	FRK	0.12	0.18	lasso	5	0.16	8.0e-12	-5.9	6.0	2.2e-09	-1.00	0.01	0.99	TRUE
12	The Cancer Genome Atlas	Prostate Adenocarcinoma	FRK	0.10	0.08	lasso	1	0.05	3.2e-06	-5.9	5.9	3.3e-09	-1.00	0.01	0.99	FALSE
8	GTEx	Pancreas	FRK	0.09	0.13	lasso	5	0.09	1.2e-04	-5.9	5.9	3.4e-09	-1.00	0.01	0.98	FALSE
4	GTEx	Esophagus Mucosa	NT5DC1	0.09	0.08	lasso	2	0.05	2.9e-04	-5.9	5.9	3.6e-09	-1.00	0.01	0.98	FALSE
14	The Cancer Genome Atlas	Thyroid Carcinoma	FRK	0.08	0.09	lasso	2	0.09	5.0e-09	-5.9	5.9	3.8e-09	-1.00	0.01	0.99	FALSE
9	GTEx	Thyroid	FRK	0.08	0.10	lasso	3	0.09	4.6e-07	-5.9	5.9	4.6e-09	-0.99	0.01	0.99	FALSE
10	METSIM	Adipose	NT5DC1	0.11	0.08	lasso	8	0.09	8.2e-14	-5.8	5.7	9.0e-09	-0.98	0.01	0.99	FALSE
3	GTEx	Colon Transverse	FRK	0.14	0.16	lasso	4	0.14	5.7e-07	-5.9	5.7	1.1e-08	-0.99	0.01	0.99	FALSE
13	The Cancer Genome Atlas	Stomach Adenocarcinoma	FRK	0.03	0.00	blup	94	0.03	4.6e-03	-5.9	5.7	1.2e-08	-0.88	0.02	0.83	FALSE
5	GTEx	Muscle Skeletal	NT5DC1	0.16	0.17	lasso	10	0.17	1.1e-16	-5.9	5.7	1.4e-08	-0.95	0.01	0.99	FALSE
6	GTEx	Muscle Skeletal	RP3-486I3.5	0.08	0.04	enet	12	0.03	2.8e-04	-5.9	5.5	4.1e-08	-0.91	0.01	0.99	FALSE
11	The Cancer Genome Atlas	Colon Adenocarcinoma	FRK	0.10	0.10	lasso	7	0.09	4.2e-06	-5.9	5.4	5.8e-08	-0.96	0.01	0.99	FALSE
1	GTEx	Cells EBV-transformed lymphocytes	FRK	0.12	0.07	enet	12	0.09	8.1e-04	4.5	5.4	6.4e-08	-0.87	0.04	0.89	FALSE
7	GTEx	Nerve Tibial	NT5DC1	0.16	0.12	lasso	4	0.13	2.1e-09	-5.8	5.4	6.9e-08	-0.93	0.01	0.99	FALSE