TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
LDL Cholesterol
:
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chr11:17,923,676-19,345,331
Best TWAS P=5.16e-08 · Best GWAS P=2.88e-07 conditioned to 0.889
18M
18.2M
18.4M
18.6M
18.8M
19M
19.2M
19.4M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Lung Squamous Cell Carcinoma
SPTY2D1
0.03
0.00
blup
43
0.01
2.0e-02
-4.9
-5.4
5.2e-08
0.93
0
0.99
TRUE
1
GTEx
Cells Transformed fibroblasts
SPTY2D1
0.31
0.27
lasso
6
0.26
2.5e-19
-5.1
-5.2
1.8e-07
1.00
0
1.00
FALSE
2
GTEx
Cells Transformed fibroblasts
SPTY2D1-AS1
0.14
0.12
lasso
6
0.11
9.0e-09
-5.1
-5.2
2.3e-07
0.99
0
0.99
FALSE