Best TWAS P=5.16e-08 · Best GWAS P=2.88e-07 conditioned to 0.889
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | SPTY2D1 | 0.31 | 0.27 | lasso | 6 | 0.26 | 2.5e-19 | -5.1 | -5.2 | 1.8e-07 | 1.00 | 0 | 1.00 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | SPTY2D1-AS1 | 0.14 | 0.12 | lasso | 6 | 0.11 | 9.0e-09 | -5.1 | -5.2 | 2.3e-07 | 0.99 | 0 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | SPTY2D1 | 0.03 | 0.00 | blup | 43 | 0.01 | 2.0e-02 | -4.9 | -5.4 | 5.2e-08 | 0.93 | 0 | 0.99 | TRUE |