Best TWAS P=6.3e-13 · Best GWAS P=1.93e-28 conditioned to 3.34e-22
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | USP24 | 0.20 | 0.04 | enet | 37 | 0.12 | 2.9e-07 | -0.424 | 5.7 | 1.5e-08 | 0.19 | 0.84 | 0.01 | FALSE |
| 2 | GTEx | Lung | USP24 | 0.16 | 0.03 | lasso | 15 | 0.04 | 5.6e-04 | -7.620 | 5.2 | 2.1e-07 | 0.16 | 0.97 | 0.00 | FALSE |
| 3 | GTEx | Stomach | USP24 | 0.14 | 0.01 | lasso | 5 | 0.00 | 2.0e-01 | -4.900 | 7.2 | 6.3e-13 | 0.23 | 0.16 | 0.07 | TRUE |
| 4 | METSIM | Adipose | PARS2 | 0.07 | 0.00 | blup | 537 | 0.02 | 2.3e-04 | 0.011 | -6.3 | 2.5e-10 | -0.14 | 0.18 | 0.07 | FALSE |