TWAS hub - USP24

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.2010	0.0530	5.4e-06	0.044	NA	0.123	NA	0.048	1.9e-03	NA	2.9e-07	NA	1.2e-03
2	GTEx	Artery Tibial	0.0842	0.0303	1.9e-03	0.048	NA	0.014	NA	0.027	1.1e-04	NA	2.6e-02	NA	3.3e-03
3	GTEx	Esophagus Muscularis	0.1230	0.0430	1.2e-03	0.002	NA	0.018	NA	0.012	2.3e-01	NA	2.8e-02	NA	6.0e-02
4	GTEx	Lung	0.1593	0.0418	5.4e-06	0.032	NA	0.036	NA	0.039	1.6e-03	NA	8.4e-04	NA	5.6e-04
5	GTEx	Nerve Tibial	0.1062	0.0430	3.5e-03	0.094	NA	0.046	NA	0.076	3.7e-07	NA	3.1e-04	NA	4.9e-06
6	GTEx	Skin Not Sun Exposed Suprapubic	0.1250	0.0510	7.0e-03	0.015	NA	0.031	NA	0.017	5.0e-02	NA	7.9e-03	NA	3.7e-02
7	GTEx	Skin Sun Exposed Lower leg	0.2140	0.0490	1.7e-08	0.129	NA	0.098	NA	0.106	7.7e-11	NA	1.6e-08	NA	4.1e-09
8	GTEx	Stomach	0.1400	0.0530	3.2e-03	0.012	NA	-0.006	NA	0.004	8.7e-02	NA	7.9e-01	NA	2.0e-01
9	GTEx	Thyroid	0.1210	0.0350	3.4e-05	0.081	NA	0.082	NA	0.098	9.4e-07	NA	7.3e-07	NA	6.2e-08
10	METSIM	Adipose	0.0406	0.0162	3.0e-03	0.034	0.009	0.030	0.017	0.035	6.5e-06	1.2e-02	2.4e-05	1.3e-03	5.4e-06
11	YFS	Blood	0.1359	0.0234	3.5e-14	0.092	0.064	0.095	0.095	0.095	1.9e-28	4.0e-20	1.9e-29	2.2e-29	2.0e-29

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
LDL Cholesterol	9.0	14.3	51.7	5.7	2.1	4.0	5.2	1.3	1.3	3.5	7.2	2.7	1.0	1.6
Sensitivity / hurt feelings	7.5	12.8	18.0	-3.2	-4.2	-3.3	-3.7	-4.2	-3.8	-3.7	-3.1	-4.1	-3.9	-0.8
Frequency of depressed mood in last 2 weeks	6.3	8.9	14.8	-3.5	-3.0	-2.5	-3.1	-2.9	-3.9	-3.1	-3.4	-3.0	-2.7	-0.7
Neuroticism score	5.7	11.9	18.2	-2.6	-4.0	-2.9	-3.3	-4.0	-4.3	-3.5	-3.8	-3.7	-3.8	-0.9
Neuroticism	5.5	13.2	18.7	-3.2	-4.3	-3.4	-3.5	-4.3	-3.8	-3.5	-3.8	-4.0	-3.9	-0.8
Pulse wave reflection index	5.5	6.7	10.6	1.7	2.7	2.2	3.2	2.8	2.3	3.3	2.7	2.9	2.7	1.3
Frequency of tenseness / restlessness in last 2 weeks	5.3	8.2	12.9	-1.0	-2.8	-2.7	-3.1	-2.4	-2.9	-3.4	-3.6	-2.7	-3.3	-2.7
Chronic bronchitis/emphysema (mother)	5.3	6.2	10.6	0.7	2.2	2.2	2.9	1.9	1.7	3.0	3.3	2.3	3.0	3.0
Neuroticism (Nagel 2018)	5.2	12.3	16.6	-2.6	-4.0	-3.3	-3.5	-3.9	-4.1	-3.6	-3.5	-3.7	-4.0	-1.6
Medication: Co-codamol	5.2	6.1	11.6	-2.1	-2.9	-2.5	-2.2	-3.2	-3.4	-2.3	-0.8	-2.8	-2.4	1.1
Diverticular disease/diverticulitis (self-reported)	5.2	6.2	9.1	-2.4	-2.5	-2.4	-2.9	-2.4	-2.3	-3.0	-2.2	-2.5	-2.8	-1.6
Other serious medical condition/disability diagnosed by doctor	5.0	6.5	12.7	-1.2	-3.1	-1.4	-3.0	-3.6	-2.2	-2.9	-2.3	-3.2	-2.7	-0.5
Illnesses of siblings	5.0	7.0	14.7	3.8	2.7	2.3	2.7	2.5	3.5	2.4	1.8	2.7	2.8	1.0
Worry (Nagel 2018)	4.9	10.4	14.1	-1.5	-3.7	-3.2	-3.2	-3.6	-3.6	-3.4	-3.3	-3.5	-3.8	-1.8
Mood swings	4.9	8.9	15.5	-2.6	-3.0	-2.6	-3.2	-2.7	-3.9	-3.1	-3.6	-3.0	-3.0	-1.3
Frequency of tiredness / lethargy in last 2 weeks	4.8	7.9	12.8	-1.7	-2.9	-2.6	-2.9	-2.5	-3.6	-3.2	-3.1	-2.9	-3.2	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	4.7	6.0	10.8	-2.1	-3.1	-2.4	-2.5	-3.3	-2.4	-2.3	-2.1	-3.0	-2.1	0.9
Prostate Cancer	4.3	6.0	8.3	2.6	2.5	1.9	2.4	2.3	2.7	2.8	2.9	2.4	2.9	1.4
Financial difficulties in last 2 years	4.3	5.8	10.0	-2.1	-2.1	-3.2	-2.4	-1.9	-2.9	-2.6	-2.7	-2.1	-2.3	-1.8
Alcohol intake versus 10 years previously	4.3	6.5	10.1	-1.8	-2.8	-2.9	-2.9	-3.1	-1.5	-2.6	-3.2	-2.9	-2.4	-0.5
High cholesterol (Self-reported)	4.3	7.7	17.4	3.6	2.6	2.3	4.0	1.8	2.2	2.5	4.2	2.9	0.8	-1.7
Tense / ‘highly strung’	3.9	6.4	10.8	-2.0	-2.8	-2.6	-2.3	-2.9	-3.3	-2.6	-2.4	-2.5	-2.6	-1.1
Unable to work because of sickness or disability	3.9	5.0	7.2	-1.7	-2.4	-2.1	-2.4	-2.7	-1.3	-2.6	-2.7	-2.3	-2.6	-1.5
Depressed Affect (Nagel 2018)	3.8	8.0	11.8	-2.9	-3.0	-2.7	-2.7	-2.9	-3.4	-3.0	-2.6	-2.8	-3.3	-1.4
Medication: Paracetamol	3.8	6.3	9.0	-2.3	-2.3	-2.0	-2.5	-2.2	-2.5	-2.8	-3.0	-2.3	-3.0	-2.5
Miserableness	3.8	6.6	15.3	-3.9	-2.3	-2.4	-2.1	-2.3	-3.3	-2.5	-2.3	-2.3	-2.7	-1.5
Headache pain in last month	3.7	6.4	9.1	-2.8	-2.5	-2.7	-2.6	-2.7	-3.0	-2.8	-2.1	-2.7	-2.4	-0.3
Worrier / anxious feelings	3.6	6.7	10.7	-2.0	-2.7	-1.4	-2.6	-2.5	-3.3	-2.8	-2.9	-2.7	-3.2	-1.7
Medication: Paracetamol	3.5	5.4	8.0	-2.0	-2.0	-2.2	-2.3	-2.1	-2.1	-2.7	-2.5	-2.2	-2.8	-2.4
Guilty feelings	3.4	5.1	13.5	-1.8	-2.7	-0.8	-2.0	-2.8	-3.7	-1.9	-2.2	-2.5	-2.0	1.1
Depression (Nagel 2018)	3.2	4.8	7.4	-1.8	-2.4	-2.7	-2.3	-2.1	-2.7	-2.5	-1.9	-2.2	-2.2	-0.7
Townsend deprivation index at recruitment	2.9	4.1	8.1	-2.8	-1.6	-1.9	-1.9	-1.5	-2.0	-2.0	-2.6	-1.8	-2.2	-1.7
Pulse rate, automated reading	2.9	9.4	13.9	-1.4	-3.4	-2.2	-3.5	-3.1	-3.7	-3.5	-3.3	-3.4	-3.5	-1.8
Illnesses of siblings: Diabetes	2.9	3.6	6.6	-1.7	-2.2	-2.2	-2.6	-2.1	-1.4	-2.0	-1.1	-2.4	-1.7	0.0
Eye problems/disorders: Diabetes related eye disease	2.8	3.0	5.1	-1.7	-1.9	-1.4	-1.8	-1.7	-2.3	-1.9	-1.6	-1.9	-1.8	-0.4
Mouth/teeth dental problems: Dentures	2.8	4.7	7.7	-0.9	-2.4	-1.6	-2.1	-2.1	-2.3	-2.2	-2.8	-2.1	-2.6	-2.2
Supplements: Vitamin C	2.8	3.3	6.1	-1.1	-2.5	-1.0	-2.4	-2.1	-1.1	-1.9	-2.0	-2.4	-1.8	0.3
Fed-up feelings	2.7	4.8	17.1	-1.3	-2.1	-1.9	-1.9	-2.1	-4.1	-2.0	-2.2	-2.1	-2.2	-0.5
Serious illness, injury or assault to yourself	2.7	3.3	6.3	-1.3	-1.4	-1.3	-2.1	-1.7	-0.9	-2.4	-1.6	-1.7	-2.3	-2.5
High blood pressure (siblings)	2.7	3.8	10.8	-3.0	-1.9	-1.3	-1.8	-1.7	-3.3	-1.6	-1.4	-1.8	-1.8	-0.1
Pulse wave peak to peak time	2.7	3.1	5.1	-0.9	-2.2	-1.2	-2.2	-2.1	-1.6	-2.0	-2.1	-2.1	-1.5	0.1
Overall health rating	2.7	5.8	9.7	-1.2	-2.3	-2.2	-2.6	-2.1	-2.8	-3.1	-2.1	-2.2	-2.9	-2.5
Vitamin and mineral supplements	2.6	3.6	6.9	0.7	2.6	1.5	2.3	2.3	1.2	2.0	2.1	2.4	1.9	-0.3
Pulse wave Arterial Stiffness index	2.5	3.0	4.8	0.9	2.2	1.0	2.2	2.0	1.6	2.0	2.2	2.0	1.4	-0.1
Pain experienced in last month	2.5	4.2	7.5	2.4	1.7	2.4	1.6	2.0	2.7	2.2	1.5	1.8	2.4	1.1
Schizophrenia (2018)	2.2	4.6	6.7	-2.6	-2.2	-1.7	-2.4	-2.0	-1.7	-2.5	-2.2	-2.3	-2.3	-1.0
Diabetes (mother)	2.2	2.8	5.5	-0.3	-2.0	-2.3	-1.8	-2.3	-1.0	-1.9	-0.8	-2.0	-2.0	0.0
Stomach or abdominal pain in last month	2.2	2.7	6.0	-2.5	-1.5	-2.4	-1.4	-1.7	-1.5	-1.5	-1.6	-1.6	-1.2	-0.0
Worry too long after embarrassment	2.2	3.7	7.8	-1.7	-2.8	-1.0	-1.9	-2.7	-1.8	-1.4	-1.9	-2.5	-1.5	1.1
Average weekly red wine intake	2.2	3.3	4.7	0.6	1.9	1.6	1.9	2.0	2.2	2.0	2.1	1.9	2.0	0.9
Long-standing illness, disability or infirmity	2.2	3.4	6.1	-0.6	-1.6	-1.0	-1.8	-1.9	-2.1	-2.5	-1.5	-1.6	-2.5	-2.3
Frequency of unenthusiasm / disinterest in last 2 weeks	2.1	2.7	5.7	-0.5	-1.7	-2.4	-1.9	-1.7	-1.8	-1.8	-1.6	-1.8	-1.5	-0.4
Medication for pain relief, constipation, heartburn	2.1	3.6	10.6	1.1	1.4	1.0	1.7	1.3	2.1	2.4	1.7	1.3	2.6	3.3
Suffer from ‘nerves’	2.1	3.3	7.6	-0.9	-2.3	-1.3	-1.7	-2.2	-2.8	-1.7	-1.4	-1.9	-1.9	-0.6
Ulcerative Colitis (UC)	2.0	3.7	6.6	0.7	2.4	1.6	2.2	2.2	1.2	2.6	2.0	2.2	2.3	0.8
Medication for hormone replacement therapy	2.0	2.2	3.9	-1.5	-1.9	-1.5	-1.3	-2.0	-1.0	-1.2	-1.4	-1.8	-1.6	0.4
Nervous feelings	2.0	3.7	10.9	-0.6	-1.6	-0.6	-1.4	-1.5	-3.3	-2.0	-2.3	-1.3	-2.3	-2.4
Pulse rate	2.0	3.4	7.3	-1.4	-1.6	-1.6	-2.1	-1.8	-2.7	-1.9	-2.1	-1.9	-1.7	-0.7
Average weekly beer plus cider intake	2.0	2.9	5.6	-0.1	-2.4	-1.3	-2.1	-2.3	0.0	-1.1	-2.3	-2.3	-0.8	1.7
Type 2 Diabetes (T2D) (2012)	1.9	2.1	4.6	-0.7	-1.3	-0.7	-1.8	-1.0	-0.6	-1.8	-1.6	-1.3	-2.1	-2.0
Primary Biliary Cirrhosis	1.8	2.6	4.5	-1.4	-1.7	-1.7	-1.7	-1.3	-1.6	-1.4	-2.1	-1.7	-1.6	-1.1
Heel T-Score	1.8	14.7	21.4	3.9	3.7	4.6	4.0	3.4	3.3	4.1	4.1	3.8	4.2	2.5
Alcohol intake frequency.	1.8	4.2	6.2	-1.4	-2.4	-1.9	-2.3	-2.4	-1.8	-2.5	-1.9	-2.4	-2.2	-0.4
Osteoarthritis (self-reported)	1.8	2.3	3.9	-1.0	-2.0	-0.6	-1.8	-1.9	-1.5	-1.7	-1.2	-1.7	-1.8	-0.4
Medication: Gliclazide	1.8	2.0	3.2	1.8	1.4	0.9	1.4	1.2	1.8	1.6	1.4	1.3	1.7	0.6
Cardiovascular Disease	1.7	5.5	11.4	2.6	2.1	2.8	2.9	1.8	2.4	2.0	3.4	2.6	0.8	-1.3
Diabetes diagnosed by doctor	1.7	2.8	6.9	-1.0	-1.2	-2.0	-1.3	-1.5	-1.2	-2.1	-0.9	-1.3	-2.0	-2.6
Back pain experienced in last month	1.7	2.4	5.6	-0.7	-1.7	-1.3	-1.3	-2.4	-2.0	-1.3	-1.0	-1.8	-1.4	1.5
Medication: Simvastatin	1.6	2.3	6.2	2.0	1.2	1.4	2.2	0.8	1.1	1.2	2.5	1.5	0.3	-1.2
Medication: Cholesterol lowering	1.6	2.5	5.8	1.9	1.4	1.2	2.3	0.6	1.5	1.1	2.4	1.5	-0.1	-1.6
Illness, injury, bereavement, stress in last 2 years	1.6	2.0	3.7	1.2	1.2	1.5	1.6	1.1	1.9	1.7	1.5	1.3	1.3	0.9
Cholesterol lowering medication	1.6	2.4	9.7	1.5	1.0	1.7	2.4	0.6	0.6	1.2	3.1	1.4	0.4	-0.1
Heart disease (siblings)	1.6	2.0	3.7	-1.3	-1.1	-1.9	-1.2	-1.4	-1.6	-1.4	-0.6	-1.2	-1.7	-1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	1.5	2.2	3.3	-1.7	-1.6	-1.1	-1.4	-1.7	-1.2	-1.6	-1.8	-1.5	-1.6	-0.8
Mouth/teeth dental problems: Mouth ulcers	1.5	2.3	5.2	1.5	2.0	0.7	1.6	2.3	-0.1	1.5	1.5	1.9	1.7	0.0
Diabetes (father)	1.4	1.7	8.3	0.2	-0.7	-1.1	-1.4	-0.4	-0.3	-1.7	-1.3	-0.6	-1.4	-2.9
Medication: Seretide 50 evohaler	1.4	1.6	3.6	0.7	1.9	-0.3	1.2	1.7	1.6	0.7	1.0	1.6	1.1	-1.2
Smoking status: Current	1.4	2.2	5.7	-1.8	-1.3	-2.4	-1.2	-1.2	-0.8	-1.0	-2.3	-1.4	-1.1	-0.4
Pack years adult smoking proportion	1.3	2.0	4.3	-2.1	-1.1	-1.1	-1.0	-0.7	-1.9	-1.3	-1.9	-0.8	-1.3	-1.4
Medication for cholesterol, blood pressure or diabetes	1.3	2.1	3.7	-1.7	-1.5	-1.4	-1.7	-0.9	-1.8	-1.1	-1.9	-1.5	-0.2	1.4
Migraine (self-reported)	1.3	1.6	4.7	-0.4	-1.3	-2.2	-1.4	-1.4	-0.5	-1.5	-0.8	-1.4	-1.2	-0.0
Age at last live birth	1.3	1.8	3.1	-1.3	-1.6	-0.8	-1.8	-1.7	-1.3	-1.4	-0.7	-1.8	-1.4	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.5	2.7	-1.1	-1.6	-1.5	-1.2	-1.6	-0.9	-1.5	-0.2	-1.4	-1.1	0.6
Irritable Bowel Disease (IBD)	1.2	2.9	4.8	0.1	2.0	1.8	1.8	2.1	1.7	2.2	1.3	1.9	1.9	0.1
Lung FEV1/FVC ratio	1.2	6.3	8.6	2.5	2.7	2.4	2.6	2.7	2.9	2.4	2.7	2.7	2.5	0.4
Systolic blood pressure, automated reading	1.2	3.6	6.0	-0.2	2.3	1.9	1.8	2.4	2.4	1.0	1.4	2.4	1.0	-2.4
Current tobacco smoking	1.2	2.0	5.5	-2.0	-1.3	-2.4	-1.1	-1.3	-0.7	-0.8	-2.1	-1.4	-0.9	-0.1
Supplements: Glucosamine	1.2	1.6	2.9	1.2	1.0	1.7	1.4	1.1	1.1	1.3	1.3	1.3	1.4	1.2
Number of incorrect matches in round	1.2	2.0	4.1	-1.3	-1.5	-1.0	-1.2	-1.2	0.3	-1.9	-1.2	-1.3	-2.0	-1.8
Breastfed as a baby	1.2	1.4	2.6	1.2	1.2	0.4	1.0	1.3	1.6	1.4	0.9	1.1	1.6	1.0
Knee pain experienced in last month	1.2	1.9	2.9	-1.7	-1.1	-1.6	-1.4	-1.4	-0.6	-1.7	-1.2	-1.3	-1.6	-1.1
Loneliness, isolation	1.2	1.7	3.7	-0.7	-1.3	-1.5	-1.2	-1.1	-1.9	-1.2	-1.8	-1.2	-1.2	-0.4
Medication: Atorvastatin	1.2	1.5	6.6	0.9	0.8	1.0	1.8	0.3	1.3	1.1	2.6	1.0	0.3	-0.3
Ovarian Cancer	1.1	1.4	2.7	-0.3	-1.6	-0.6	-1.5	-1.4	-1.0	-1.2	-1.4	-1.5	-1.2	-0.5
Ulcerative Colitis	1.1	1.5	2.5	-0.3	1.5	1.2	1.3	1.4	1.4	1.5	1.2	1.3	1.6	0.3
Hand grip strength (left)	1.1	2.8	5.7	2.4	1.9	1.1	1.2	2.0	2.1	1.4	1.4	1.7	1.8	-0.1
Hand grip strength (right)	1.1	2.9	4.5	2.0	2.1	1.3	1.6	2.0	2.1	1.4	1.3	1.9	1.6	-0.6
Multivitamins +/- minerals	1.1	1.4	3.3	-0.9	-1.8	-0.9	-1.1	-1.5	-0.6	-1.1	-1.1	-1.5	-1.0	0.9
Loud music exposure frequency	1.1	1.2	3.5	-0.7	-0.5	-1.6	-1.0	-0.6	-1.1	-1.3	-0.9	-0.6	-1.1	-1.9
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.2	7.1	2.7	1.6	0.1	1.3	1.6	2.0	1.1	1.1	1.6	1.2	-0.4
Alcohol drinker status: Never	1.1	1.3	3.0	-0.8	-1.4	-1.1	-1.0	-1.4	-1.7	-1.0	-1.1	-1.2	-1.0	-0.1
Diastolic blood pressure, automated reading	1.1	3.3	8.1	0.7	2.5	1.5	1.5	2.8	1.7	1.1	1.1	2.4	1.4	-2.2
Bipolar Disorder (2011)	1.0	0.9	2.2	1.3	1.0	0.3	1.3	0.7	1.5	1.0	0.0	1.1	1.0	0.3
Body Mass Index (BMI) (2010)	1.0	1.4	2.7	-0.9	-1.6	-1.1	-1.0	-1.5	-1.6	-0.7	-0.6	-1.4	-0.7	1.4
Schizophrenia (2014)	1.0	2.1	3.4	-1.8	-1.4	-1.3	-1.6	-1.2	-1.5	-1.7	-1.3	-1.5	-1.6	-0.9
Relative age voice broke	1.0	1.5	7.0	-1.3	-1.1	-0.8	-0.7	-1.4	-2.6	-0.8	-0.6	-1.1	-1.2	-0.0
Wheeze or whistling in the chest in last year	1.0	1.9	3.8	-1.9	-1.0	-1.3	-1.4	-1.4	-1.1	-1.4	-1.7	-1.2	-1.4	-0.5
Medication: Blood pressure	1.0	1.7	3.8	1.4	1.5	1.3	1.1	1.3	2.0	0.9	1.4	1.5	0.6	-1.0
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.1	2.4	-0.8	-1.1	-1.5	-1.1	-0.9	-0.9	-1.2	-0.7	-1.1	-1.0	-1.1
Commuting to job workplace: Walk	1.0	1.1	3.2	1.8	-0.8	-0.4	-1.2	-0.2	-1.4	-1.0	-1.0	-0.8	-1.0	-1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	3.9	2.0	1.2	1.5	0.8	1.3	-0.4	0.4	1.2	1.0	0.8	-0.6
Pain type(s) experienced in last month: Hip pain	1.0	1.2	6.8	-2.6	-0.5	-1.4	-0.4	-0.9	-1.4	-0.6	-0.3	-0.7	-0.3	0.7
Pack years of smoking	1.0	1.5	3.8	-2.0	-0.9	-1.1	-0.8	-0.5	-1.7	-1.1	-1.5	-0.6	-1.0	-1.3
Bipolar Disorder or Schizophrenia	0.9	2.2	4.6	-2.1	-1.3	-1.4	-1.7	-1.1	-0.5	-1.8	-1.7	-1.4	-1.6	-1.3
Major Depression (MDD)	0.9	1.1	4.3	-2.1	-0.9	-0.7	-1.0	-0.7	-0.6	-1.2	-1.1	-0.8	-1.0	-0.7
Reaction Time	0.9	1.6	2.4	-1.5	-1.1	-1.0	-1.4	-1.2	-1.2	-1.5	-1.5	-1.3	-1.4	-0.6
Alcohol usually taken with meals	0.9	1.5	5.7	0.7	1.3	1.1	1.7	0.8	0.2	1.3	2.4	1.1	0.8	0.7
Mouth/teeth dental problems	0.9	1.4	4.3	0.4	0.7	0.9	1.0	0.5	2.1	1.0	1.6	0.6	1.2	1.8
Illnesses of mother	0.9	1.1	1.9	-1.1	-1.0	-0.2	-1.3	-1.0	-0.4	-1.4	-1.2	-1.0	-1.2	-1.1
Peak expiratory flow (PEF)	0.9	2.0	4.4	1.1	2.1	0.7	1.2	2.1	1.2	1.4	1.4	1.8	1.3	-0.5
Comparative body size at age 10	0.9	2.5	4.3	0.5	1.9	1.8	1.4	2.1	1.4	1.6	1.5	1.8	2.1	0.4
Neck or shoulder pain in last month	0.9	1.3	4.2	-1.1	-0.9	-1.0	-0.8	-0.9	-2.1	-1.2	-0.6	-0.8	-1.4	-1.1
Medication: Ibuprofen	0.9	1.1	1.8	-0.8	-1.2	-0.6	-1.0	-1.3	-1.4	-1.1	-0.8	-1.3	-1.2	0.2
Commuting to job workplace: Public transport	0.9	1.0	2.5	0.2	-1.3	-0.6	-1.2	-0.9	-1.6	-0.6	-1.3	-1.2	-0.3	1.0
Age started oral contraceptive pill	0.9	1.1	2.5	-0.4	-1.6	-1.5	-1.4	-0.9	0.2	-1.0	-0.6	-1.4	-1.0	0.2
Systolic Blood Pressure	0.8	3.8	7.2	0.4	2.4	2.7	1.8	2.2	2.1	1.0	1.8	2.5	1.2	-1.9
Hearing difficulty/problems with background noise	0.8	1.3	3.8	-0.7	1.1	2.0	1.7	0.6	0.6	1.0	0.9	1.3	1.0	0.5
Father’s age at death	0.8	1.1	5.2	0.5	0.4	1.1	0.3	0.5	1.2	1.1	0.6	0.3	1.3	2.3
Serious illness, injury or assault of a close relative in last 2 years	0.8	1.0	1.8	0.5	1.3	1.0	1.1	1.3	0.6	1.1	0.8	1.1	1.0	0.1
Mother’s age at death	0.8	1.0	3.6	1.9	0.9	1.4	0.8	0.9	0.1	1.0	0.7	0.9	0.8	-0.1
Breast Cancer	0.7	1.6	5.2	-2.3	-1.4	0.3	-1.2	-1.2	-1.1	-1.1	-1.2	-1.3	-1.4	0.2
HbA1C	0.7	0.8	5.2	0.2	-0.3	-0.2	-0.4	0.1	0.2	-0.6	-1.0	-0.2	-1.4	-2.3
Waist Hip Ratio (WHR)	0.7	3.3	6.8	-2.3	-1.7	-0.8	-2.2	-1.2	-0.3	-2.0	-2.6	-1.7	-1.9	-1.8
Hearing difficulty/problems: Yes	0.7	1.1	2.9	-1.7	-1.0	-1.1	-0.9	-1.5	-0.3	-1.0	-0.8	-1.1	-1.0	0.5
Medication: Ramipril	0.7	0.9	4.4	-1.2	-0.1	-1.1	-0.8	-0.2	0.4	-0.9	-0.4	-0.3	-0.9	-2.1
Medication: Lansoprazole	0.7	0.8	3.6	1.9	0.2	0.7	0.5	0.1	1.1	0.5	1.4	0.5	0.3	0.6
Lung cancer (father)	0.7	0.8	2.2	0.3	-0.6	-1.4	-0.9	-0.4	-1.5	-1.0	-0.7	-0.7	-0.9	-1.0
Qualifications: O levels/GCSEs or equivalent	0.7	1.2	3.4	1.9	0.8	1.5	0.8	1.4	0.5	0.9	1.0	1.1	0.8	0.1
Glaucoma (self-reported)	0.7	0.8	3.8	-0.7	0.2	1.5	0.3	-0.0	0.7	0.8	0.8	0.1	0.7	1.9
Number of full brothers	0.7	0.9	2.9	0.0	-0.6	-0.6	-0.8	-0.3	-1.5	-1.0	-0.5	-0.6	-1.1	-1.7
Eye problems/disorders: None of the above	0.7	0.8	3.1	1.8	1.0	-0.2	0.5	1.1	1.0	0.2	-0.2	0.8	0.7	-1.2
Friendships satisfaction	0.7	0.9	3.2	-1.3	-0.9	-1.0	-0.5	-0.8	-1.8	-0.8	-0.4	-0.8	-0.8	0.1
Eye problems/disorders: Cataract	0.7	0.8	2.7	-0.7	0.2	0.7	0.9	0.3	-0.3	1.4	1.0	0.5	0.8	1.6
Illnesses of father: None of the above (group 1)	0.7	0.8	1.5	-0.9	-0.9	-0.8	-0.9	-1.0	-1.2	-0.7	-0.7	-1.0	-0.5	1.1
Wears glasses or contact lenses	0.7	0.8	2.3	-0.2	0.7	1.5	1.5	0.8	0.0	1.2	0.7	1.0	0.7	-0.1
Ever smoked	0.7	1.2	3.1	-1.8	-1.0	-1.0	-1.0	-1.5	-1.0	-0.9	-0.3	-1.3	-0.7	0.9
Neuroticism (2016)	0.6	0.9	1.7	-0.9	-1.2	0.9	-0.6	-1.1	-0.6	-0.9	-0.8	-0.8	-1.3	-0.8
Smoking Status	0.6	1.5	2.6	-1.2	-1.3	-1.3	-1.2	-1.5	-1.4	-1.0	-0.9	-1.6	-1.1	0.5
Respiratory disease	0.6	1.4	3.8	-2.0	-0.6	-0.3	-0.9	-0.9	-1.7	-1.5	-0.4	-0.7	-1.5	-1.3
Ever had hysterectomy (womb removed)	0.6	0.6	1.1	1.0	0.8	0.6	0.6	1.0	0.3	0.5	1.0	1.0	0.8	-0.8
Qualifications: CSEs or equivalent	0.6	0.8	2.3	-0.1	1.3	0.4	0.5	1.5	0.2	0.3	0.1	1.1	0.8	-1.4
Happiness	0.6	0.7	2.3	0.0	-0.7	-1.5	-1.0	-0.4	-0.8	-0.9	-1.3	-0.8	-0.5	-0.1
Exposure to tobacco smoke at home	0.6	0.7	2.9	0.3	0.9	1.2	0.5	0.9	1.7	0.4	0.0	0.8	0.7	-0.6
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	1.7	1.0	1.1	0.4	0.6	1.3	0.4	0.8	-0.2	1.1	1.2	-0.4
Birth weight	0.6	1.2	5.5	1.8	0.1	-1.3	-0.3	0.5	0.7	-0.6	-1.3	0.1	-0.3	-2.4
Shortness of breath walking on level ground	0.6	0.7	1.4	0.7	1.2	0.9	1.0	1.0	0.7	0.5	0.4	1.1	0.4	-1.0
Family relationship satisfaction	0.6	0.7	1.1	-0.6	-1.1	-0.9	-0.8	-1.0	-0.7	-0.8	-0.9	-1.0	-0.8	0.0
Commuting to job workplace: Car/motor vehicle	0.6	0.7	1.6	0.2	1.1	-0.0	1.1	0.4	1.3	0.8	1.2	0.9	0.6	0.0
Illnesses of father: Heart disease	0.6	0.9	1.8	0.9	0.7	1.3	1.3	0.3	0.9	0.9	1.3	0.9	0.6	0.4
Ever had bowel cancer screening	0.6	0.7	2.1	1.2	0.0	1.5	0.5	-0.1	-1.0	0.6	1.2	0.1	0.1	1.2
Ever taken oral contraceptive pill	0.6	0.7	3.3	-1.8	-0.7	-1.1	-0.5	-0.6	-0.3	-0.7	-0.7	-0.6	-0.2	0.5
Supplements: Calcium	0.6	0.7	1.3	0.5	-1.1	-0.1	-1.0	-1.1	-0.4	-0.7	-1.0	-1.1	-0.6	0.8
Schizophrenia vs Biploar Disorder	0.5	0.7	2.2	-0.0	-0.8	-1.2	-0.6	-1.0	-1.5	-0.6	-0.4	-0.9	-0.6	0.6
Rheumatoid Arthritis	0.5	0.6	2.9	0.0	0.3	0.5	0.1	1.0	1.4	-0.2	-0.6	0.6	-0.1	-1.7
Type 2 Diabetes (T2D) (2018)	0.5	0.9	4.1	-1.4	-0.1	-1.5	-0.1	-0.4	0.1	-1.1	-0.1	-0.2	-0.9	-2.0
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	1.3	1.1	0.8	0.4	1.0	0.9	0.4	0.7	0.7	0.9	0.5	-0.6
Medication: Atenolol	0.5	0.6	2.0	1.4	-0.1	-0.6	-0.3	-0.4	1.2	-0.6	0.2	-0.2	-0.9	-1.2
Medication: Levothyroxine sodium	0.5	0.8	2.7	1.5	0.2	1.4	0.4	0.3	-1.1	0.4	1.6	0.3	0.1	0.1
Sitting height	0.5	3.5	8.0	2.8	2.0	1.2	1.7	1.9	1.6	1.9	1.6	1.8	2.2	1.2
Heart attack	0.5	0.6	1.4	-0.2	-1.0	-0.9	-0.5	-1.2	0.5	-0.6	-0.5	-1.0	-1.1	-0.0
Pain all over the body in last month	0.5	0.5	2.6	-1.0	0.1	-0.4	-0.3	0.4	-1.6	-0.6	0.0	-0.0	-0.3	-1.2
Length of working week for main job	0.5	0.5	2.9	-0.2	0.5	0.8	0.6	0.6	1.7	0.4	0.0	0.6	0.5	-0.4
Qualifications: College or University degree	0.5	1.6	4.2	1.4	1.6	2.0	1.1	1.3	0.7	1.1	1.3	1.4	1.0	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.5	1.6	1.3	0.7	0.4	0.4	1.1	0.8	0.8	-0.2	0.7	0.8	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	3.3	-0.8	1.4	0.1	0.8	1.5	1.8	0.7	0.6	1.2	0.9	-0.4
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.8	0.8	0.5	1.1	0.7	0.2	1.1	0.6	1.4	0.6	0.4	0.4
Supplements: Fish oil (including cod liver oil)	0.5	0.6	2.1	0.7	0.0	1.4	0.3	0.1	-1.1	0.6	1.3	0.1	0.1	1.0
Illnesses of father: High blood pressure	0.5	0.6	1.9	-0.6	-0.8	-0.5	-0.6	-0.4	-0.6	-0.9	-0.6	-0.5	-0.8	-1.4
Risk taking	0.5	0.7	1.2	-0.4	-0.5	-0.8	-0.8	-0.7	1.1	-1.1	-1.1	-0.6	-0.8	-1.0
Ever had prostate specific antigen (PSA) test	0.5	0.6	2.7	-1.6	-0.2	0.0	0.2	-0.4	-1.0	0.2	0.8	-0.3	0.1	1.4
Alcohol drinker status: Previous	0.5	0.6	1.1	-0.7	-1.0	-1.0	-0.7	-0.6	0.3	-1.0	-0.4	-0.7	-1.0	-0.4
Coronary Artery Disease (CAD)	0.4	0.5	1.4	1.2	-0.5	-0.2	0.5	-0.9	-0.5	0.4	1.1	-0.3	0.0	0.6
Blood Platelet Count	0.4	5.2	9.7	-3.1	-2.2	-2.5	-2.2	-2.5	-2.3	-2.5	-1.9	-2.2	-2.2	-0.5
Number of treatments/medications taken	0.4	0.6	3.3	-0.6	-0.3	-0.2	-0.4	-0.4	0.6	-0.9	0.4	-0.3	-1.3	-1.8
Taking other prescription medications	0.4	0.6	3.1	-0.1	-0.3	-0.4	-0.3	-0.7	-1.8	-0.7	0.7	-0.4	-1.0	-0.9
Diabetes (self-reported)	0.4	0.6	2.5	-0.9	-0.2	-1.0	-0.4	-0.5	-0.5	-1.1	-0.0	-0.4	-0.8	-1.6
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.5	-0.1	0.6	1.2	0.7	-0.1	0.8	0.7	1.1	0.4	0.3	0.5
Fluid intelligence score	0.4	0.8	1.8	-0.6	-1.2	-1.3	-0.5	-1.0	-0.7	-0.4	-0.2	-1.0	-0.7	1.3
Falls in the last year	0.4	0.5	1.2	0.5	-0.5	-1.1	-0.9	-0.6	0.2	-0.9	-0.5	-0.8	-0.9	-0.5
Depression (self-reported)	0.4	0.5	1.7	0.3	-0.2	-1.3	-0.8	-0.3	0.4	-0.6	-1.3	-0.4	-0.4	-0.9
Standing height	0.4	3.6	17.1	4.1	1.9	0.3	1.5	1.8	2.0	1.2	1.6	1.8	1.2	-0.7
Hypothyroidism/myxoedema (self-reported)	0.4	0.9	4.0	2.0	0.2	1.4	0.3	0.3	-0.6	0.0	1.5	0.4	-0.2	-0.7
Medication: Amlodipine	0.4	0.6	1.5	-0.1	-0.8	-0.8	-0.7	-1.2	-0.1	-0.4	0.8	-0.9	-0.6	1.2
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.2	0.2	1.1	-0.5	0.8	0.7	0.4	0.2	1.0	0.9	-0.2	-1.1
Number of full sisters	0.4	0.4	1.5	-1.2	-0.5	0.7	-0.3	-0.3	-1.1	0.0	-0.6	-0.4	-0.3	0.6
Had major operations	0.4	0.4	1.5	-0.2	-0.6	-0.6	-0.1	-1.2	-0.3	-0.4	-0.8	-0.6	-0.9	-0.7
Medication: Aspirin	0.4	0.6	3.8	0.8	-0.2	0.2	0.4	-0.2	0.3	-0.5	0.7	0.2	-1.0	-1.9
Arm fat percentage (left)	0.4	1.6	3.2	-1.5	-1.4	-1.4	-1.5	-1.0	-0.1	-1.3	-1.8	-1.4	-1.2	-0.6
Medication for cholesterol	0.4	0.6	1.7	1.0	1.0	0.4	0.2	1.3	0.6	0.5	-0.2	0.9	1.1	-0.2
Osteoporosis (self-reported)	0.4	0.5	2.0	-1.4	-0.6	-0.4	-0.4	-0.5	-1.2	-0.0	-0.1	-0.5	-0.2	0.7
Medication: Aspirin	0.4	0.6	4.0	0.8	-0.0	0.1	0.4	0.0	0.3	-0.4	0.6	0.3	-0.9	-2.0
Eye problems/disorders: Glaucoma	0.4	0.5	1.7	-1.3	-0.5	0.0	-0.9	-0.8	-0.1	-0.4	-0.0	-0.8	-0.4	1.1
Medication: Bendroflumethiazide	0.4	0.5	1.0	-0.3	0.6	1.0	0.7	0.8	0.9	0.8	0.9	0.8	0.6	0.4
Commuting to job workplace: Cycle	0.4	0.5	1.5	0.8	0.7	0.5	0.3	1.2	1.1	0.6	0.5	0.7	0.4	-0.2
Myopia	0.4	0.6	1.7	0.3	0.3	1.3	0.8	0.3	-0.8	1.1	0.8	0.5	0.8	1.0
Basal cell carcinoma (self-reported)	0.4	0.5	3.1	0.8	0.3	-0.1	-0.3	0.4	0.8	-0.4	-0.7	0.1	-0.5	-1.8
Crohns Disease (2017)	0.3	0.6	2.4	-0.4	0.7	0.8	0.5	0.9	1.5	0.8	-0.1	0.7	0.5	-0.5
Crohns Disease (2012)	0.3	0.5	2.8	0.3	0.1	0.9	0.0	0.4	0.9	0.0	-0.6	0.2	-0.3	-1.7
HDL Cholesterol	0.3	0.5	0.9	-0.2	0.9	-0.2	0.8	0.8	0.5	1.0	-0.1	0.8	0.9	0.7
Lupus	0.3	0.5	4.0	2.0	-0.6	0.0	-0.4	-0.1	-0.3	0.1	-0.4	-0.4	-0.1	0.1
Lung FVC	0.3	1.4	11.9	-3.5	-0.0	-1.2	-0.3	-0.1	-0.1	-0.4	-1.0	-0.1	-0.4	-0.8
Average weekly spirits intake	0.3	0.4	2.5	1.6	-0.2	0.2	-0.1	-0.6	-0.1	-0.5	0.1	-0.1	-0.5	-0.8
Angina	0.3	0.4	2.2	1.5	-0.3	0.6	0.5	-0.5	-0.2	0.1	0.7	0.2	-0.5	-0.6
Supplements: Zinc	0.3	0.3	0.8	-0.1	-0.4	-0.3	-0.5	-0.1	-0.6	-0.6	-0.8	-0.4	-0.8	-0.9
Medication: Metformin	0.3	0.4	1.6	-0.8	-0.2	-0.6	-0.2	-0.6	-0.3	-0.8	-0.2	-0.3	-0.6	-1.3
Trunk fat percentage	0.3	1.0	2.8	-1.1	-0.9	-0.6	-1.3	-0.5	0.5	-1.1	-1.7	-1.0	-1.0	-1.0
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.3	-1.1	-0.3	-0.6	0.1	-0.5	-0.7	-0.2	0.4	-0.4	-0.2	0.8
Chronic bronchitis/emphysema (father)	0.3	0.4	1.1	0.0	-0.5	-1.0	-0.7	-0.3	-0.4	-0.4	-1.0	-0.5	-0.4	-0.8
Waist circumference	0.3	1.1	3.0	-1.2	-0.7	-0.4	-1.1	-0.4	-0.1	-1.3	-1.5	-0.7	-1.1	-1.7
Past tobacco smoking	0.3	0.5	1.4	0.5	0.7	0.6	0.6	1.0	1.2	0.7	-0.2	0.8	0.8	-0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	1.5	0.1	-0.9	0.6	-0.9	-1.2	-0.5	-0.7	-0.6	-1.0	-0.4	1.1
Arm fat percentage (right)	0.3	1.2	2.8	-1.5	-1.2	-1.0	-1.2	-0.8	0.1	-1.1	-1.7	-1.1	-1.0	-0.6
Trunk fat-free mass	0.3	1.9	6.0	2.5	1.6	0.4	1.2	1.5	1.4	1.0	1.1	1.4	1.3	-0.1
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	2.4	0.2	1.2	-0.2	0.6	1.5	1.5	0.7	0.4	1.2	0.8	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.3	-1.1	-0.4	0.1	-0.3	-0.6	-1.1	-0.4	-0.3	-0.5	-0.6	0.2
Trunk predicted mass	0.3	1.8	6.0	2.5	1.6	0.4	1.1	1.5	1.4	0.9	1.0	1.4	1.3	-0.2
Body fat percentage	0.3	1.2	3.0	-1.5	-1.0	-0.7	-1.4	-0.6	0.4	-1.1	-1.7	-1.0	-1.0	-0.9
Arm fat-free mass (right)	0.3	1.6	2.9	1.7	1.6	0.6	1.0	1.6	1.4	0.7	1.2	1.5	1.1	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	1.1	0.4	0.7	0.4	0.3	0.6	1.0	0.4	0.0	0.7	0.5	-0.6
Mouth/teeth dental problems: Loose teeth	0.3	0.4	0.9	-0.2	0.4	0.6	1.0	0.6	-0.3	0.6	0.7	0.6	0.6	0.8
Angina (self-reported)	0.3	0.4	2.3	1.5	-0.2	0.7	0.5	-0.4	-0.2	0.1	0.7	0.2	-0.5	-0.8
Medication: Omeprazole	0.3	0.3	1.3	0.2	-0.6	-0.3	-0.5	-0.5	0.4	-0.9	-0.3	-0.3	-0.7	-1.1
Heart disease (mother)	0.3	0.3	0.8	-0.3	0.0	0.7	0.7	-0.1	-0.9	0.6	0.8	0.2	0.3	0.8
Arm predicted mass (right)	0.3	1.5	3.8	1.9	1.5	0.6	0.9	1.4	1.5	0.7	1.0	1.3	1.0	-0.6
Chest pain or discomfort	0.3	0.4	0.8	0.2	-0.6	-0.8	-0.2	-0.7	-0.9	-0.6	-0.3	-0.5	-0.9	-0.8
Leg pain on walking	0.3	0.4	1.8	-0.8	0.5	-0.9	0.2	0.7	0.3	-0.3	0.1	0.4	-0.2	-1.4
Hypertension (Self-reported)	0.3	0.9	2.0	0.4	0.7	1.3	0.8	0.5	1.2	0.4	1.2	0.9	-0.3	-1.4
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.0	0.1	-0.6	-0.4	-0.8	-0.9	-0.5	-0.2	0.3	-0.7	-0.4	1.0
Number of self-reported non-cancer illnesses	0.3	0.5	1.7	0.8	0.7	1.0	0.6	0.3	0.3	0.1	1.1	0.6	-0.3	-1.3
Average weekly champagne plus white wine intake	0.3	0.4	2.0	1.4	0.2	-0.1	0.5	-0.0	0.1	0.5	0.8	0.4	0.4	0.6
Medication: Blood pressure	0.3	0.5	1.0	-0.5	0.7	1.0	0.8	0.8	0.5	0.5	1.0	0.8	0.3	-0.6
Medication: Lisinopril	0.3	0.3	1.1	-1.1	0.8	-0.3	0.6	0.5	0.2	0.2	0.1	0.6	0.1	-1.0
Leg fat percentage (left)	0.3	1.1	3.3	-1.7	-0.6	-0.5	-1.3	-0.2	0.2	-0.9	-1.8	-0.7	-0.8	-1.1
Number of operations (self-reported)	0.3	0.5	1.2	0.1	-0.6	-0.3	-0.4	-1.0	-0.5	-0.9	-0.2	-0.7	-1.1	-0.8
Irritability	0.3	0.4	1.7	0.2	-0.5	-0.9	-0.3	-0.4	-1.3	-0.2	-1.1	-0.5	-0.3	0.1
Ever depressed for a whole week	0.3	0.4	1.8	-0.5	-0.4	0.5	0.6	-0.4	0.5	0.5	0.5	-0.1	0.3	1.3
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.0	0.3	-0.7	-0.6	-0.7	-0.3	-0.0	-1.0	-0.7	-0.4	-0.7	-1.0
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.0	0.1	-0.8	-0.7	-0.2	-1.0	0.4	-0.4	-0.2	-0.7	-1.0	-0.1
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	2.3	-1.0	-0.1	-0.4	-0.2	-0.3	-1.5	-0.0	0.1	-0.2	0.1	0.9
Bipolar Disorder (2018)	0.2	0.4	1.7	-0.2	0.7	-0.2	0.4	0.8	1.3	0.3	0.1	0.6	0.4	-0.8
Intelligence (Savage-Jansen 2018)	0.2	0.5	1.7	0.6	-0.8	-0.5	-0.5	-0.7	-0.9	-0.2	-0.9	-0.7	-0.1	1.3
Alzheimer’s Disease (in mother)	0.2	0.2	0.6	0.8	0.2	-0.1	0.1	0.5	-0.2	0.5	-0.2	0.3	0.8	0.5
Alzheimer’s Disease (in father)	0.2	0.2	0.8	0.1	0.4	0.8	0.9	0.1	0.4	0.3	0.5	0.5	-0.1	-0.3
Alzheimer’s Disease (including proxy)	0.2	0.3	0.8	-0.4	-0.3	-0.5	-0.6	-0.6	-0.4	-0.8	-0.9	-0.6	-0.7	0.0
Mean Putamen Volume	0.2	0.2	0.8	0.9	0.2	0.4	-0.1	0.0	-0.8	0.1	-0.2	0.1	0.5	0.3
Fasting Glucose	0.2	0.2	0.5	0.7	0.2	0.4	0.3	0.4	-0.4	0.2	-0.4	0.5	-0.4	-0.7
Triglycerides	0.2	0.4	1.5	1.2	0.7	0.5	0.6	0.8	0.6	0.3	0.4	0.7	0.1	-0.1
Blood Red Count	0.2	2.0	5.7	-1.2	-1.0	-1.6	-1.8	-0.9	-1.0	-1.5	-2.4	-1.3	-1.2	-1.0
Blood White Count	0.2	1.3	4.5	-2.1	-0.9	-1.3	-1.3	-1.0	-0.6	-0.8	-1.1	-1.2	-0.6	0.4
Hypothyroidism (self reported)	0.2	0.6	1.6	1.3	-0.5	0.8	-0.4	-0.4	-0.8	-0.6	0.9	-0.4	-0.9	-0.7
Chronotype (morning person)	0.2	0.5	2.9	-0.7	-0.2	0.3	-0.6	0.1	-1.7	-0.5	-0.5	-0.2	-0.4	-0.8
Average weekly fortified wine intake	0.2	0.2	1.4	-1.2	0.3	0.3	0.3	0.5	-0.2	0.1	0.1	0.3	-0.1	-0.8
Maternal smoking around birth	0.2	0.3	0.6	-0.4	-0.7	-0.8	-0.4	-0.5	-0.6	-0.5	-0.7	-0.4	-0.0	0.3
High blood pressure	0.2	0.5	1.8	-0.2	0.1	1.0	0.1	-0.2	0.7	-0.2	0.8	0.3	-0.9	-1.4
Hair/balding pattern: Pattern 2	0.2	0.3	0.9	-0.1	-0.5	0.2	-0.4	-0.9	-0.9	-0.7	0.1	-0.5	-0.7	-0.0
Forced vital capacity (FVC)	0.2	0.6	2.4	-0.3	0.9	-0.7	0.3	1.1	1.6	0.4	-0.2	0.8	0.5	-0.5
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.5	-0.5	-0.7	0.1	-0.3	-0.7	-0.1	-0.5	0.1	-0.5	-0.3	0.4
Qualifications: None of the above	0.2	0.3	1.2	-1.1	-0.5	-1.0	-0.3	-0.4	0.4	-0.4	-0.6	-0.4	-0.3	-0.3
Hair/balding pattern: Pattern 3	0.2	0.3	0.8	-0.2	-0.5	-0.6	-0.4	-0.6	-0.4	-0.6	-0.2	-0.5	-0.9	-0.5
Number of live births	0.2	0.2	1.1	-0.2	-0.4	-1.1	-0.4	-0.4	-0.7	-0.4	0.2	-0.4	-0.3	0.0
Noisy workplace	0.2	0.3	2.0	-1.4	-0.0	-1.0	0.2	-0.2	-0.0	0.0	0.5	-0.0	-0.1	-0.0
Asthma	0.2	0.5	2.0	-1.3	0.1	0.8	0.0	-0.3	-1.4	-0.3	0.6	-0.0	-0.6	-0.3
Hair/balding pattern: Pattern 4	0.2	0.5	1.2	-1.0	-0.7	-0.6	-0.6	-0.4	-1.1	-0.1	-0.9	-0.7	-0.2	0.9
Birth weight of first child	0.2	0.4	1.3	-0.9	-0.3	-0.5	-0.5	-0.1	-0.5	-0.4	-1.0	-0.3	-0.6	-1.1
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.9	-0.8	0.1	-0.9	0.2	0.0	-0.9	-0.3	-0.3	0.1	-0.1	-0.7
Blood clot in the leg (DVT)	0.2	0.3	2.0	-0.6	-0.1	-0.5	-0.2	-0.1	-1.4	0.0	0.0	-0.1	0.2	0.7
Gout (self-reported)	0.2	0.2	0.5	0.6	-0.3	-0.7	-0.5	-0.3	0.2	-0.6	-0.4	-0.3	-0.4	-0.6
Leg fat percentage (right)	0.2	0.8	2.7	-1.5	-0.6	-0.5	-1.2	-0.2	0.2	-0.8	-1.6	-0.7	-0.6	-0.8
Number of children fathered	0.2	0.2	0.5	0.0	-0.5	-0.5	-0.4	-0.5	-0.3	-0.2	-0.7	-0.4	-0.1	0.5
Age at first live birth	0.2	0.3	0.7	-0.6	-0.4	-0.5	-0.8	-0.5	-0.6	-0.6	-0.4	-0.7	-0.8	-0.3
Health satisfaction	0.2	0.2	0.6	-0.5	-0.1	-0.6	-0.3	-0.2	-0.8	-0.5	-0.4	-0.3	-0.4	-0.5
Emphysema/chronic bronchitis	0.2	0.3	1.3	-0.4	-0.0	0.0	-0.1	0.4	-1.2	-0.3	-0.5	0.2	-0.2	-0.9
Medication: Allopurinol	0.2	0.3	0.9	0.6	-0.3	-0.6	-0.4	-0.5	0.1	-0.7	-0.5	-0.3	-0.8	-1.0
Mean time to correctly identify matches	0.2	0.4	0.8	-0.9	-0.6	0.3	-0.4	-0.8	-0.8	-0.5	-0.2	-0.6	-0.6	0.3
Comparative height size at age 10	0.2	1.2	4.9	2.2	1.1	-0.5	0.4	1.1	1.0	0.1	0.4	0.9	0.1	-1.9
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.4	0.7	-0.0	-0.6	-0.6	-0.1	-0.5	-0.6	-0.6	-0.3	-0.2	-0.6
Smoking status: Previous	0.2	0.3	1.0	0.6	-0.2	0.2	-0.1	-0.5	-0.9	-0.5	1.0	-0.3	-0.4	-0.1
Whole body fat-free mass	0.2	1.2	4.4	2.1	1.3	0.2	0.8	1.2	1.2	0.6	0.8	1.2	0.9	-0.4
Qualifications: nursing, teaching	0.2	0.3	1.5	-0.0	0.5	1.2	0.6	0.5	0.2	0.3	-0.2	0.6	0.0	-0.3
Breast cancer (self-reported)	0.2	0.3	1.1	0.4	-0.5	0.9	-0.2	-0.6	-0.1	-0.1	0.0	-0.4	-1.0	-0.3
Asthma (self-reported)	0.2	0.3	1.6	-1.2	0.1	0.9	0.0	-0.3	-0.9	-0.2	0.5	-0.0	-0.5	-0.2
Whole body water mass	0.2	1.2	4.1	2.0	1.3	0.1	0.9	1.2	1.3	0.6	0.9	1.2	1.0	-0.4
Hearing aid user	0.2	0.2	1.0	-0.8	0.1	-1.0	0.0	0.1	-0.7	0.1	0.4	0.1	-0.1	-0.2
Basal metabolic rate	0.2	0.8	2.9	1.7	1.1	0.1	0.6	1.1	1.2	0.4	0.6	1.0	0.8	-0.4
Arm fat-free mass (left)	0.2	1.0	1.9	1.4	1.3	0.4	0.7	1.2	1.3	0.5	0.7	1.2	0.8	-0.7
Vascular/heart problems diagnosed by doctor	0.2	0.6	1.4	-0.2	-0.3	-1.2	-0.7	-0.1	-1.2	-0.3	-1.1	-0.6	0.5	1.1
Arm predicted mass (left)	0.2	1.2	2.0	1.3	1.4	0.6	0.9	1.4	1.4	0.7	0.9	1.3	1.0	-0.4
Verbal and Numeric Reasoning (VNR)	0.1	0.3	2.3	-0.6	-0.4	-0.4	0.3	-0.2	-0.4	0.4	0.2	-0.2	0.2	1.5
Age at First Birth	0.1	0.2	1.0	1.0	0.0	-0.4	0.5	0.3	0.5	0.6	0.2	0.3	0.3	0.3
BMI	0.1	0.3	2.6	-1.6	-0.0	-0.3	-0.2	-0.3	0.4	-0.4	-0.2	-0.2	0.1	0.3
Height	0.1	2.5	14.1	3.8	1.0	-0.8	0.6	0.9	0.7	-0.4	-0.0	0.8	-0.8	-3.0
Allergy or Eczema	0.1	0.1	0.7	-0.9	-0.0	0.2	0.3	-0.5	0.5	0.2	-0.2	-0.1	0.1	0.5
Tanning	0.1	1.4	2.6	-0.1	0.8	0.5	1.5	1.0	1.3	1.5	1.5	1.3	1.6	1.0
Relative age of first facial hair	0.1	0.2	1.2	0.1	-0.3	0.4	0.2	-0.6	-1.1	0.3	0.1	-0.2	-0.2	0.7
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.5	-0.4	-0.7	0.1	-0.0	-0.5	-0.4	-0.2	-0.1	-0.2	-0.5	-0.2
Severe depression (siblings)	0.1	0.1	0.3	-0.2	-0.2	-0.6	-0.3	-0.1	-0.5	-0.1	-0.3	-0.2	0.2	0.2
Leg fat-free mass (left)	0.1	0.6	2.3	1.5	0.9	-0.2	0.5	0.9	0.8	0.2	0.4	0.8	0.6	-0.4
Age when periods started (menarche)	0.1	0.3	0.9	-0.1	0.7	0.5	0.8	0.6	0.1	0.4	0.2	0.8	0.0	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	1.1	1.0	0.2	1.1	0.2	-0.0	-0.2	0.4	0.2	0.1	0.5	0.7
High blood pressure (mother)	0.1	0.2	0.4	-0.5	-0.2	-0.3	-0.3	-0.3	-0.2	-0.4	-0.4	-0.2	-0.6	-0.6
Impedance of leg (left)	0.1	0.3	1.4	0.1	-0.4	0.1	-0.8	-0.2	0.1	-0.3	-1.2	-0.4	-0.5	-0.7
Leg predicted mass (left)	0.1	0.5	2.4	1.5	0.9	-0.3	0.5	0.8	0.8	0.2	0.4	0.8	0.5	-0.4
Trunk fat mass	0.1	0.6	1.5	-0.5	-0.4	-0.6	-0.9	-0.1	0.9	-0.8	-1.2	-0.5	-0.7	-1.1
Had menopause	0.1	0.1	0.6	-0.1	-0.4	0.6	-0.1	0.0	-0.0	0.0	-0.3	-0.1	-0.6	-0.8
Had other major operations	0.1	0.2	1.0	-0.4	-0.3	-0.2	0.1	-0.4	-1.0	-0.2	0.3	-0.2	-0.2	0.2
Allergy	0.1	0.3	1.1	0.7	-0.3	-0.5	-0.4	0.3	0.5	-0.4	-0.6	-0.1	-0.0	-1.0
Weight	0.1	0.4	1.2	0.6	0.7	0.2	0.3	0.9	1.1	0.1	0.0	0.6	0.3	-0.8
Impedance of arm (right)	0.1	0.3	0.8	-0.0	-0.7	-0.4	-0.4	-0.5	-0.4	-0.4	-0.9	-0.5	-0.8	-0.6
Time employed in main current job	0.1	0.1	0.3	0.4	0.2	-0.6	0.0	0.1	0.4	0.0	0.3	0.1	0.3	-0.2
Prospective memory result	0.1	0.1	0.4	-0.4	-0.2	0.0	-0.5	-0.3	0.1	-0.4	-0.6	-0.3	0.2	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.3	1.1	0.4	0.3	-1.1	-0.2	0.6	1.0	-0.2	-0.2	0.3	0.1	-0.6
Impedance of arm (left)	0.1	0.6	1.1	-0.1	-1.1	-0.9	-0.6	-0.8	-0.7	-0.6	-0.9	-0.9	-0.8	-0.2
Forced vital capacity (FVC), Best measure	0.1	0.4	1.7	0.0	0.6	-1.0	0.3	0.8	1.3	0.3	0.1	0.5	0.4	-0.2
Exposure to tobacco smoke outside home	0.1	0.2	1.5	0.3	0.1	0.2	-0.2	0.4	-1.2	0.0	-0.1	0.1	0.1	-0.4
Whole body fat mass	0.1	0.5	1.3	-0.7	-0.4	-0.5	-0.8	-0.1	0.7	-0.7	-1.1	-0.4	-0.5	-0.9
Leg fat mass (right)	0.1	0.3	1.0	-0.4	-0.2	-0.4	-0.6	0.1	0.6	-0.5	-1.0	-0.2	-0.3	-0.8
Leg fat-free mass (right)	0.1	0.7	2.7	1.6	1.1	-0.1	0.6	1.0	1.0	0.3	0.6	0.9	0.6	-0.5
Mineral and other dietary supplements	0.1	0.2	0.9	-0.6	0.1	-0.9	-0.2	-0.1	-0.1	-0.3	-0.7	-0.1	0.0	-0.4
Leg predicted mass (right)	0.1	0.7	2.7	1.6	1.1	-0.1	0.6	1.0	1.0	0.3	0.6	0.9	0.6	-0.5
Arm fat mass (left)	0.1	0.4	1.0	-0.7	-0.6	-0.6	-0.7	-0.3	0.4	-0.7	-1.0	-0.6	-0.5	-0.5
Financial situation satisfaction	0.1	0.2	0.8	-0.2	0.1	-0.3	-0.2	0.2	0.3	-0.3	-0.9	-0.0	-0.1	-0.8
Leg fat mass (left)	0.1	0.4	1.5	-0.6	-0.2	-0.4	-0.8	0.1	0.5	-0.6	-1.2	-0.3	-0.5	-1.0
Blood Eosinophil Count	0.0	0.4	1.3	0.3	0.2	0.3	0.8	-0.2	0.6	0.6	0.7	0.3	0.7	1.2
Hair Pigment	0.0	0.6	3.2	-0.2	0.0	-0.5	0.2	0.4	-1.1	-0.3	0.6	0.1	-1.2	-1.8
Impedance of leg (right)	0.0	0.2	1.4	0.1	-0.4	0.1	-0.6	-0.2	-0.1	-0.3	-1.2	-0.4	-0.3	-0.3
Hayfever, allergic rhinitis or eczema	0.0	0.1	0.2	-0.1	-0.1	0.1	0.2	-0.5	0.4	0.2	-0.4	-0.2	-0.3	0.3
Body mass index (BMI)	0.0	0.2	1.1	-1.1	-0.1	0.0	-0.3	0.1	0.3	-0.3	-0.6	-0.1	-0.1	-0.3
Hip circumference	0.0	0.1	0.3	0.4	0.1	-0.1	0.1	0.3	0.6	0.1	-0.0	0.2	0.1	-0.3
Qualifications: A levels/AS levels or equivalent	0.0	0.1	0.7	0.8	-0.3	-0.1	-0.2	0.2	-0.1	-0.1	-0.1	-0.1	0.0	0.2
Arm fat mass (right)	0.0	0.2	0.5	-0.4	-0.2	-0.4	-0.4	0.1	0.7	-0.3	-0.7	-0.2	-0.2	-0.4
Fractured/broken bones in last 5 years	0.0	0.1	0.3	0.1	-0.1	-0.5	0.2	0.3	-0.3	-0.1	0.0	0.3	-0.0	-0.2
Impedance of whole body	0.0	0.2	0.6	0.1	-0.6	-0.1	-0.6	-0.4	-0.0	-0.4	-0.8	-0.6	-0.6	-0.4

Hub : Genes

USP24

Models

Trait associations