Best TWAS P=1.08e-14 · Best GWAS P=1.73e-47 conditioned to 1.63e-31
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | DYNC2LI1 | 0.31 | 0.15 | lasso | 12 | 0.23 | 1.2e-27 | 5.106 | -5.5 | 3.4e-08 | -0.01 | 1.00 | 0.00 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | PLEKHH2 | 0.08 | 0.00 | blup | 127 | 0.02 | 1.1e-03 | -0.034 | 5.9 | 3.6e-09 | 0.07 | 0.01 | 0.61 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | DYNC2LI1 | 0.08 | 0.02 | enet | 5 | 0.03 | 7.7e-05 | 3.075 | -5.7 | 1.4e-08 | -0.19 | 0.57 | 0.08 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ABCG5 | 0.05 | 0.04 | blup | 75 | 0.02 | 1.6e-03 | -4.546 | 7.7 | 1.1e-14 | 0.35 | 0.42 | 0.13 | TRUE |