Best TWAS P=2.41e-08 · Best GWAS P=2.15e-07 conditioned to 0.0667
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Left Ventricle | MKRN2 | 0.21 | 0.05 | enet | 15 | 0.14 | 1.1e-07 | -3.5 | -5.6 | 2.4e-08 | 0.69 | 0.11 | 0.87 | TRUE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | RAF1 | 0.03 | 0.02 | blup | 59 | 0.02 | 1.6e-03 | -4.2 | 5.2 | 2.4e-07 | -0.60 | 0.02 | 0.90 | FALSE |