TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
LDL Cholesterol
:
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chr2:20,062,043-21,958,745
Best TWAS P=6.25e-114 · Best GWAS P=4.48e-114 conditioned to 1
20M
20.5M
21M
21.5M
22M
0
20
40
60
80
100
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
APOB
0.13
0.12
lasso
2
0.12
1.0e-14
22.7
-22.7
6.2e-114
-1.00
0.00
1.00
TRUE
2
YFS
Blood
HS1BP3
0.03
0.00
blup
536
0.01
3.7e-04
-2.6
6.6
3.5e-11
0.01
0.62
0.01
TRUE