Best TWAS P=9.13e-14 · Best GWAS P=3.54e-14 conditioned to 0.00344
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Colon Adenocarcinoma | HOXD9 | 0.06 | 0.04 | blup | 53 | 0.02 | 0.02020 | -5.8 | -6.2 | 6.4e-10 | 0.77 | 0.03 | 0.74 | FALSE |
2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | HOXD11 | 0.03 | 0.02 | enet | 7 | 0.03 | 0.00058 | 3.9 | -5.2 | 1.7e-07 | 0.40 | 0.20 | 0.03 | FALSE |
3 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | HOXD9 | 0.05 | 0.02 | blup | 54 | 0.03 | 0.00607 | -5.9 | -7.5 | 9.1e-14 | 0.76 | 0.02 | 0.45 | TRUE |