TWAS hub - LEKR1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2160	0.0410	1.7e-13	0.078	0.143	0.152	0.152	0.155	8.5e-10	4.3e-17	4.8e-18	4.8e-18	2.2e-18
2	METSIM	Adipose	0.0870	0.0254	5.4e-07	0.095	0.054	0.086	0.085	0.091	5.4e-14	1.4e-08	7.4e-13	9.9e-13	1.7e-13
3	TCGA	Bladder Urothelial Carcinoma	0.0960	0.0340	2.0e-07	0.140	0.087	0.108	NA	0.122	7.3e-12	7.8e-08	2.1e-09	NA	1.8e-10
4	TCGA	Breast Invasive Carcinoma	0.1296	0.0315	0.0e+00	0.158	0.141	0.151	NA	0.153	3.8e-31	1.2e-27	1.0e-29	NA	3.6e-30
5	TCGA	Cervical Squamous Cell Carcinoma	0.1840	0.0730	1.5e-05	0.115	0.095	0.103	NA	0.098	2.9e-06	2.1e-05	9.2e-06	NA	1.6e-05
6	TCGA	Colon Adenocarcinoma	0.1600	0.0550	1.6e-05	0.118	0.054	0.071	NA	0.092	2.6e-07	4.4e-04	6.7e-05	NA	5.3e-06
7	TCGA	Esophageal Carcinoma	0.2500	0.0830	2.0e-04	0.085	0.182	0.099	NA	0.107	1.2e-03	2.0e-06	4.8e-04	NA	2.9e-04
8	TCGA	Head and Neck Squamous Cell Carcinoma	0.0896	0.0313	6.2e-09	0.099	0.079	0.077	NA	0.088	3.3e-11	3.7e-09	5.4e-09	NA	4.4e-10
9	TCGA	Kidney Renal Clear Cell Carcinoma	0.2161	0.0543	0.0e+00	0.185	0.207	0.220	NA	0.213	2.0e-20	6.7e-23	2.1e-24	NA	1.5e-23
10	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1590	0.0530	9.9e-07	0.128	0.094	0.124	NA	0.128	8.5e-08	5.1e-06	1.4e-07	NA	8.4e-08
11	TCGA	Brain Lower Grade Glioma	0.0613	0.0244	5.4e-05	0.014	0.037	0.030	NA	0.025	8.2e-03	4.6e-05	2.2e-04	NA	6.6e-04
12	TCGA	Lung Adenocarcinoma	0.0890	0.0287	1.3e-09	0.116	0.093	0.101	NA	0.109	2.1e-13	5.5e-11	8.0e-12	NA	1.2e-12
13	TCGA	Lung Squamous Cell Carcinoma	0.1164	0.0434	1.4e-08	0.066	0.079	0.071	NA	0.075	5.9e-08	2.6e-09	1.7e-08	NA	6.5e-09
14	TCGA	Ovarian Serous Cystadenocarcinoma	0.2320	0.0540	1.4e-15	0.270	0.240	0.246	NA	0.257	2.1e-18	2.7e-16	9.9e-17	NA	1.6e-17
15	TCGA	Pancreatic Adenocarcinoma	0.1450	0.0580	2.9e-04	0.152	0.123	0.123	NA	0.147	6.1e-07	8.2e-06	7.7e-06	NA	9.8e-07
16	TCGA	Pheochromocytoma and Paraganglioma	0.2720	0.1090	1.8e-04	0.074	0.069	0.037	NA	0.064	7.1e-04	1.0e-03	1.3e-02	NA	1.6e-03
17	TCGA	Prostate Adenocarcinoma	0.1988	0.0488	5.6e-17	0.188	0.162	0.176	NA	0.188	2.9e-19	1.3e-16	4.6e-18	NA	2.6e-19
18	TCGA	Rectum Adenocarcinoma	0.4010	0.1080	4.4e-05	0.253	0.127	0.198	NA	0.258	1.2e-06	7.0e-04	2.1e-05	NA	9.1e-07
19	TCGA	Soft Tissue Sarcoma	0.1490	0.0600	3.3e-06	0.035	0.061	0.061	NA	0.088	3.6e-03	1.6e-04	1.7e-04	NA	6.9e-06
20	TCGA	Stomach Adenocarcinoma	0.0650	0.0280	4.4e-04	0.068	0.049	0.053	NA	0.069	1.2e-05	1.9e-04	1.0e-04	NA	1.1e-05
21	TCGA	Testicular Germ Cell Tumors	0.1160	0.0670	9.0e-03	0.028	0.033	0.012	NA	0.012	3.6e-02	2.5e-02	1.2e-01	NA	1.2e-01
22	TCGA	Thyroid Carcinoma	0.2390	0.0510	0.0e+00	0.332	0.339	0.362	NA	0.370	3.1e-33	5.1e-34	9.2e-37	NA	9.5e-38
23	TCGA	Uterine Corpus Endometrial Carcinoma	0.2070	0.0860	4.3e-03	0.141	0.086	0.070	NA	0.102	9.9e-05	2.2e-03	5.4e-03	NA	8.6e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23
Heel T-Score	33.7	268.3	349.7	11.9	16.7	17.1	16.8	18.1	16.9	16.8	17.6	15.7	17.6	10.4	17.1	14.5	16.8	17.1	14.5	16.9	17.1	18.7	18.0	12.1	18.1	17.1
Heel bone mineral density (BMD) T-score, automated (left)	24.9	56.4	71.6	5.2	7.7	7.9	7.7	8.2	7.8	6.9	8.0	7.8	8.0	5.5	7.9	6.8	7.7	7.9	6.1	8.0	7.6	8.5	8.2	5.9	8.2	7.9
Heel bone mineral density (BMD) T-score, automated (right)	21.1	48.4	63.4	4.6	7.2	7.4	7.2	7.6	7.3	6.5	7.5	7.2	7.4	4.7	7.4	6.4	7.2	7.4	5.3	7.5	6.9	8.0	7.5	5.6	7.6	7.4
Ovarian Cancer	12.7	16.7	32.7	4.1	5.2	5.3	5.4	3.6	5.3	2.9	4.5	2.3	3.1	1.0	5.3	3.3	5.2	5.3	3.0	5.1	-1.5	1.7	-0.2	5.7	1.7	5.3
Type 2 Diabetes (T2D) (2018)	7.5	14.1	17.6	-3.2	-4.2	-4.2	-4.2	-4.0	-4.2	-3.8	-4.1	-3.3	-3.9	-2.9	-4.2	-3.3	-4.1	-4.2	-3.3	-4.0	-2.9	-3.5	-3.2	-3.3	-3.7	-4.2
Pulse rate	7.5	12.6	17.8	2.5	3.8	3.8	3.7	3.9	3.7	3.0	4.0	3.8	3.6	2.5	3.7	2.9	3.9	3.7	3.0	3.8	3.1	4.2	3.6	3.5	3.7	3.7
Neuroticism	5.7	13.8	16.9	3.9	3.8	3.8	3.8	3.8	3.8	3.7	3.8	3.7	4.1	2.9	3.8	4.0	3.7	3.8	3.3	3.6	4.1	3.1	3.8	2.8	4.0	3.8
Pulse rate, automated reading	5.4	17.3	28.8	1.9	4.2	4.3	4.0	4.5	4.1	3.3	4.5	4.7	4.2	2.8	4.2	4.1	4.3	4.2	3.1	4.3	4.3	5.4	4.9	4.1	4.6	4.2
Alcohol usually taken with meals	5.2	8.4	13.0	-2.8	-2.7	-2.8	-2.8	-3.1	-2.8	-2.5	-3.0	-3.2	-3.3	-2.2	-2.8	-2.6	-2.8	-2.8	-2.4	-2.8	-3.6	-3.2	-3.5	-2.1	-3.5	-2.8
Ever had stillbirth, spontaneous miscarriage or termination	5.1	5.4	7.0	1.7	2.6	2.6	2.6	2.4	2.6	1.5	2.5	2.4	2.3	1.9	2.6	2.4	2.6	2.6	2.2	2.6	1.7	1.8	2.0	2.4	2.2	2.6
Hearing difficulty/problems: Yes	5.0	7.7	10.2	2.6	2.8	2.8	2.9	3.0	2.9	3.0	2.9	3.2	2.9	2.5	2.8	2.1	2.7	2.8	2.6	3.0	2.8	3.0	2.6	1.6	2.9	2.8
Diabetes (self-reported)	4.7	7.2	8.8	-2.0	-2.9	-3.0	-2.9	-2.9	-2.9	-2.3	-2.8	-2.3	-2.8	-2.2	-3.0	-2.8	-2.9	-3.0	-2.1	-2.8	-2.4	-2.5	-2.6	-2.5	-2.8	-3.0
Medication: Metformin	4.1	5.7	7.7	-2.3	-2.6	-2.7	-2.7	-2.4	-2.7	-2.1	-2.4	-1.6	-2.5	-2.6	-2.7	-2.8	-2.6	-2.7	-2.4	-2.5	-1.9	-1.3	-1.9	-2.1	-2.2	-2.7
Medication: Lisinopril	4.1	5.2	7.0	-2.0	-2.5	-2.5	-2.4	-2.4	-2.4	-1.3	-2.5	-2.4	-2.3	-2.6	-2.4	-2.5	-2.5	-2.4	-1.8	-2.6	-1.7	-1.9	-2.0	-2.3	-2.1	-2.5
Friendships satisfaction	4.0	5.0	10.4	-0.9	-2.3	-2.4	-2.3	-2.2	-2.3	-0.9	-2.2	-1.8	-2.4	-1.3	-2.4	-2.6	-2.3	-2.4	-1.3	-2.2	-2.3	-2.3	-2.7	-3.2	-2.5	-2.4
Illnesses of siblings: Diabetes	3.9	4.8	6.1	-2.3	-2.3	-2.3	-2.4	-2.3	-2.4	-2.0	-2.2	-2.5	-2.4	-1.9	-2.3	-2.2	-2.1	-2.3	-1.8	-2.4	-2.1	-2.0	-1.9	-1.1	-2.3	-2.3
Risk taking	3.6	5.2	7.5	-2.1	-2.5	-2.6	-2.6	-2.5	-2.6	-2.5	-2.4	-1.5	-2.6	-0.8	-2.6	-1.6	-2.5	-2.6	-2.1	-2.7	-2.2	-1.7	-2.2	-1.3	-2.5	-2.6
Diabetes (father)	3.4	4.3	5.5	-1.7	-2.3	-2.3	-2.2	-2.2	-2.2	-1.3	-2.3	-1.9	-2.1	-1.9	-2.2	-2.2	-2.4	-2.2	-2.1	-2.0	-1.7	-1.7	-2.0	-2.1	-2.0	-2.2
Average weekly red wine intake	3.4	5.0	8.8	-1.9	-2.1	-2.2	-2.2	-2.3	-2.2	-1.1	-2.1	-2.4	-2.5	-2.4	-2.2	-2.6	-2.0	-2.2	-1.8	-2.4	-3.0	-1.9	-2.8	-1.4	-2.7	-2.2
Diabetes diagnosed by doctor	3.3	5.4	7.6	-1.5	-2.6	-2.7	-2.6	-2.4	-2.6	-1.7	-2.5	-1.9	-2.3	-1.9	-2.7	-2.4	-2.6	-2.7	-1.6	-2.5	-1.5	-1.9	-2.0	-2.8	-2.2	-2.7
Ever had prostate specific antigen (PSA) test	3.2	3.7	6.3	1.3	2.1	2.0	1.9	2.2	1.9	1.8	2.3	2.5	1.9	1.5	1.9	1.2	2.2	1.9	2.1	2.0	1.5	2.4	1.9	1.4	1.9	1.9
Prostate Cancer	3.1	4.3	6.8	1.9	2.4	2.4	2.4	2.1	2.4	1.1	2.3	1.9	2.0	1.6	2.4	2.1	2.4	2.4	1.7	2.5	1.0	1.7	1.3	2.6	1.7	2.4
Diabetes (mother)	3.1	3.9	5.7	-2.0	-2.0	-1.9	-1.9	-2.2	-1.9	-2.0	-2.1	-2.4	-2.1	-1.7	-1.9	-1.6	-2.0	-1.9	-2.0	-2.0	-2.2	-2.1	-2.1	-0.6	-2.2	-1.9
Number of full sisters	3.0	3.7	5.4	-1.2	-1.9	-1.9	-1.8	-2.1	-1.9	-1.4	-2.1	-2.3	-2.0	-1.7	-1.9	-1.7	-2.0	-1.9	-2.1	-1.9	-2.0	-2.1	-2.2	-1.9	-2.1	-1.9
Triglycerides	2.9	4.8	8.3	-1.4	-2.1	-2.3	-2.2	-2.3	-2.2	-1.6	-2.2	-2.3	-2.3	-1.4	-2.3	-2.1	-2.1	-2.3	-1.9	-2.2	-2.2	-2.5	-2.4	-2.9	-2.4	-2.3
Worry (Nagel 2018)	2.8	5.9	11.7	2.3	2.2	2.3	2.3	2.5	2.3	2.2	2.2	2.7	2.8	2.1	2.3	2.9	2.1	2.3	1.8	2.2	3.4	2.4	3.0	1.5	3.0	2.3
Medication: Omeprazole	2.8	3.4	8.4	-2.2	-1.9	-1.9	-1.9	-2.0	-1.9	-2.9	-1.9	-1.3	-2.0	-1.3	-1.8	-0.9	-1.9	-1.8	-2.5	-1.7	-1.7	-1.6	-1.6	-0.7	-1.9	-1.8
Qualifications: NVQ or HND or HNC or equivalent	2.8	3.4	8.5	-0.9	-1.6	-1.6	-1.6	-2.0	-1.6	-1.4	-1.8	-1.9	-2.1	-1.1	-1.6	-1.6	-1.6	-1.6	-1.6	-1.5	-2.9	-2.5	-2.9	-1.1	-2.5	-1.6
Crohns Disease (2017)	2.6	5.7	9.1	1.4	2.4	2.4	2.3	2.6	2.3	1.2	2.5	2.6	2.6	1.8	2.4	2.4	2.3	2.4	1.5	2.5	2.8	2.9	3.0	2.9	2.8	2.4
Hair/balding pattern: Pattern 2	2.6	3.2	8.3	0.4	1.5	1.6	1.6	1.8	1.6	0.4	1.7	1.9	2.0	1.6	1.6	2.0	1.5	1.6	0.6	1.6	2.9	2.3	2.8	2.0	2.4	1.6
Smoking status: Previous	2.6	3.8	6.3	2.5	2.2	2.1	2.1	2.0	2.1	1.9	2.2	1.8	2.0	1.2	2.1	1.8	2.2	2.1	2.0	2.1	1.4	1.4	1.3	1.8	1.7	2.1
HDL Cholesterol	2.5	4.2	8.8	2.4	2.2	2.0	2.0	2.1	2.0	1.4	2.2	2.8	1.9	3.0	2.0	2.1	2.2	2.0	2.2	2.2	1.4	1.6	1.3	1.6	1.7	2.0
Neuroticism (Nagel 2018)	2.4	5.6	7.5	2.7	2.4	2.4	2.5	2.4	2.5	2.3	2.4	2.2	2.6	2.0	2.4	2.5	2.3	2.4	2.3	2.3	2.5	2.0	2.2	2.0	2.5	2.4
Irritable Bowel Disease (IBD)	2.4	5.7	9.2	1.2	2.4	2.5	2.4	2.5	2.5	1.1	2.6	2.6	2.5	1.4	2.5	2.2	2.5	2.5	1.4	2.6	2.4	2.8	2.7	3.0	2.6	2.5
Ulcerative Colitis	2.4	3.5	4.5	1.2	2.0	2.0	2.0	2.0	2.0	1.2	2.1	2.0	1.9	1.7	2.0	1.8	2.1	2.0	1.7	1.9	1.8	1.9	1.8	2.0	1.9	2.0
Frequency of depressed mood in last 2 weeks	2.4	3.3	4.5	1.9	1.9	2.0	2.1	1.9	2.0	1.0	1.9	1.8	2.0	1.1	2.0	1.4	2.0	2.0	1.0	2.1	1.6	1.5	1.7	1.8	1.9	2.0
Exposure to tobacco smoke outside home	2.4	3.2	6.0	2.3	1.8	1.8	1.9	1.9	1.8	2.4	1.8	1.1	2.1	1.5	1.8	1.7	1.8	1.8	1.7	1.8	2.1	1.2	1.8	-0.4	2.0	1.8
Osteoporosis (self-reported)	2.4	3.0	5.1	-1.5	-1.9	-1.9	-2.0	-1.9	-2.0	-2.3	-1.9	-1.8	-1.7	-1.0	-1.9	-1.1	-1.9	-1.9	-1.6	-1.9	-1.1	-1.8	-1.2	-1.1	-1.6	-1.9
Tanning	2.3	27.7	51.3	-1.7	-4.9	-5.1	-4.8	-5.4	-4.9	-4.3	-5.4	-7.2	-5.4	-2.1	-5.1	-6.0	-5.1	-5.1	-1.3	-5.2	-6.1	-6.8	-6.8	-6.2	-6.1	-5.1
Frequency of tenseness / restlessness in last 2 weeks	2.3	3.5	6.2	1.5	1.8	1.9	1.9	2.0	1.9	1.0	1.9	2.3	2.1	1.8	1.9	2.1	1.8	1.9	0.9	2.1	2.5	1.8	2.4	0.9	2.3	1.9
Worry too long after embarrassment	2.3	3.8	11.0	2.8	2.1	2.0	2.2	2.0	2.2	3.3	2.0	1.8	1.9	1.4	2.1	1.2	2.0	2.1	2.1	2.1	1.1	1.4	0.7	0.7	1.5	2.1
Bipolar Disorder (2018)	2.2	3.4	5.7	2.4	2.1	2.0	2.0	1.9	2.0	1.1	2.0	1.5	1.9	1.9	2.0	2.1	2.1	2.0	2.0	2.0	1.3	0.9	1.2	1.6	1.6	2.0
Chronotype (morning person)	2.2	5.2	8.0	-2.2	-2.4	-2.4	-2.4	-2.4	-2.4	-2.8	-2.5	-2.1	-2.5	-1.5	-2.4	-2.5	-2.5	-2.4	-1.5	-2.5	-2.1	-2.0	-2.2	-0.8	-2.4	-2.4
Had menopause	2.2	2.7	3.4	-1.4	-1.6	-1.8	-1.8	-1.8	-1.8	-1.8	-1.7	-1.4	-1.8	-1.3	-1.8	-1.4	-1.7	-1.8	-1.3	-1.8	-1.5	-1.6	-1.6	-1.4	-1.7	-1.8
Neuroticism score	2.2	4.6	6.2	2.4	2.1	2.1	2.2	2.2	2.2	1.9	2.1	2.3	2.4	2.0	2.1	2.4	2.1	2.1	1.8	2.1	2.5	1.8	2.2	1.7	2.3	2.1
Mother’s age at death	2.2	2.8	4.4	1.6	1.7	1.7	1.7	1.8	1.7	1.8	1.7	1.9	1.7	1.9	1.6	1.4	1.7	1.6	2.1	1.6	1.5	1.7	1.5	0.9	1.7	1.6
Medication: Omeprazole (e.g. Zanprol)	2.2	2.7	8.1	-2.1	-1.7	-1.6	-1.7	-1.7	-1.7	-2.8	-1.6	-1.2	-1.8	-0.9	-1.6	-0.7	-1.6	-1.6	-2.4	-1.4	-1.4	-1.2	-1.3	-0.6	-1.6	-1.6
Heart attack/myocardial infarction (self-reported)	2.2	2.9	6.1	2.1	1.7	1.7	1.7	1.8	1.7	1.8	1.6	1.1	1.9	1.8	1.7	1.7	1.6	1.7	2.5	1.6	1.9	1.0	1.6	0.6	1.8	1.7
Number of children fathered	2.1	2.4	4.8	1.5	1.8	1.8	1.8	1.5	1.7	0.9	1.7	1.3	1.5	0.7	1.8	1.8	1.8	1.8	1.4	1.8	0.6	0.9	0.9	2.2	1.2	1.8
Medication: Gliclazide	2.1	2.4	4.2	-2.1	-1.8	-1.8	-1.9	-1.6	-1.9	-1.8	-1.6	-1.2	-1.6	-1.0	-1.8	-1.0	-1.8	-1.8	-1.5	-1.7	-0.7	-1.2	-0.6	-0.8	-1.2	-1.8
Heart attack	2.0	2.6	6.0	2.1	1.6	1.6	1.6	1.6	1.6	1.9	1.5	1.0	1.7	1.8	1.6	1.6	1.5	1.6	2.4	1.5	1.7	0.9	1.4	0.6	1.6	1.6
Comparative body size at age 10	2.0	5.4	10.9	-1.8	-2.5	-2.5	-2.5	-2.3	-2.5	-1.1	-2.3	-2.1	-2.5	-1.9	-2.5	-3.3	-2.4	-2.5	-1.8	-2.5	-2.1	-1.7	-2.4	-2.4	-2.4	-2.5
Eye problems/disorders: Glaucoma	2.0	2.4	6.8	0.4	1.6	1.6	1.4	1.6	1.4	1.2	1.8	2.1	1.4	-1.0	1.5	0.8	1.7	1.5	0.6	1.6	1.0	2.2	1.7	2.6	1.5	1.5
Hayfever/allergic rhinitis (self-reported)	1.9	2.5	4.3	-1.1	-1.4	-1.5	-1.5	-1.6	-1.5	-1.4	-1.5	-1.7	-1.7	-1.1	-1.5	-1.9	-1.5	-1.5	-1.5	-1.4	-2.0	-1.9	-2.1	-0.9	-1.9	-1.5
Falls in the last year	1.9	2.6	3.5	1.7	1.7	1.7	1.7	1.7	1.7	1.4	1.8	1.2	1.8	-0.0	1.7	1.5	1.8	1.7	1.0	1.9	1.5	1.6	1.6	1.7	1.7	1.7
Tense / ‘highly strung’	1.9	3.1	5.2	1.5	1.8	1.9	1.9	1.7	1.9	1.0	1.7	1.7	1.9	1.9	1.9	2.3	1.8	1.9	0.7	1.9	2.0	1.2	1.8	1.2	1.9	1.9
Mouth/teeth dental problems: Loose teeth	1.9	2.3	4.1	2.0	1.5	1.4	1.4	1.6	1.4	1.3	1.6	2.0	1.6	1.6	1.4	1.3	1.4	1.4	1.4	1.5	1.7	1.4	1.5	0.4	1.6	1.4
Neck or shoulder pain in last month	1.9	2.7	5.7	1.8	1.6	1.6	1.6	1.8	1.6	2.2	1.8	2.3	1.5	1.9	1.5	1.0	1.7	1.5	1.1	1.7	1.2	2.4	1.1	0.1	1.5	1.5
Number of operations (self-reported)	1.8	2.6	8.1	0.1	1.7	1.7	1.5	1.7	1.6	0.5	1.9	1.7	1.5	0.1	1.7	1.5	1.8	1.7	0.6	1.5	1.3	2.1	2.0	2.9	1.7	1.7
Supplements: Calcium	1.8	2.0	3.2	-0.9	-1.4	-1.5	-1.4	-1.6	-1.4	-1.1	-1.6	-1.1	-1.6	-0.9	-1.5	-0.7	-1.4	-1.5	-1.3	-1.6	-1.6	-1.7	-1.8	-1.1	-1.7	-1.5
Impedance of whole body	1.8	9.0	13.0	1.2	3.1	3.2	3.0	3.2	3.1	2.0	3.2	3.6	3.0	2.2	3.2	3.5	3.1	3.2	1.8	3.1	2.8	3.4	3.3	3.3	3.2	3.2
Depressed Affect (Nagel 2018)	1.7	3.5	5.6	2.4	1.9	1.9	1.9	1.9	1.9	1.6	1.9	1.4	2.1	1.8	1.9	2.1	1.9	1.9	2.2	1.7	2.1	1.4	1.8	1.5	2.0	1.9
Depression (Nagel 2018)	1.7	2.5	3.6	1.5	1.7	1.8	1.7	1.7	1.7	1.3	1.8	1.2	1.8	0.4	1.8	1.6	1.9	1.8	0.8	1.8	1.4	1.3	1.6	1.6	1.7	1.8
Ever had hysterectomy (womb removed)	1.7	1.9	3.2	1.4	1.2	1.3	1.4	1.5	1.4	1.6	1.4	0.8	1.5	0.9	1.4	1.3	1.3	1.4	1.8	1.2	1.6	1.6	1.4	1.1	1.5	1.4
Serious illness, injury or assault to yourself	1.7	2.1	4.9	-1.8	-1.6	-1.5	-1.6	-1.5	-1.6	-2.2	-1.5	-1.3	-1.4	-1.0	-1.5	-0.2	-1.6	-1.5	-2.2	-1.5	-0.8	-1.4	-0.6	-0.8	-1.2	-1.5
Medication: Ibuprofen (e.g. Nurofen)	1.7	2.2	3.4	0.8	1.6	1.6	1.6	1.6	1.6	0.9	1.5	1.2	1.5	1.9	1.6	1.4	1.5	1.6	1.0	1.7	1.5	1.7	1.5	0.9	1.6	1.6
Leg pain on walking	1.7	2.2	5.2	-2.3	-1.6	-1.5	-1.5	-1.4	-1.5	-1.0	-1.6	-1.9	-1.4	-2.3	-1.4	-1.0	-1.7	-1.4	-2.0	-1.6	-0.6	-0.6	-0.6	-0.6	-1.0	-1.4
Ulcerative Colitis (UC)	1.6	2.9	5.4	0.8	1.8	1.9	1.9	1.8	1.9	0.6	1.9	1.8	1.7	1.0	2.0	1.4	1.9	2.0	1.2	2.0	1.2	1.8	1.5	2.3	1.6	2.0
Lung FEV1/FVC ratio	1.6	8.1	16.6	-0.8	-2.8	-2.9	-2.6	-3.1	-2.6	-1.7	-3.2	-2.9	-3.0	-1.3	-2.8	-2.8	-3.0	-2.8	-0.4	-3.0	-3.2	-3.7	-4.1	-3.2	-3.4	-2.8
Supplements: Zinc	1.6	1.7	3.5	-1.9	-1.3	-1.2	-1.2	-1.5	-1.2	-1.8	-1.4	-1.3	-1.3	-1.5	-1.1	-0.3	-1.3	-1.1	-1.5	-1.4	-1.4	-1.4	-0.9	0.4	-1.3	-1.1
Impedance of leg (left)	1.6	7.6	9.9	1.8	2.9	3.0	2.9	3.0	2.9	2.6	3.0	3.1	2.8	2.5	3.0	2.9	2.9	3.0	2.0	3.0	2.4	2.9	2.7	2.1	2.8	3.0
Impedance of arm (right)	1.6	7.6	13.8	0.6	2.6	2.8	2.6	2.8	2.6	1.3	2.8	3.1	2.9	2.4	2.8	3.7	2.6	2.8	1.3	2.7	3.4	3.0	3.7	3.1	3.2	2.8
Father’s age at death	1.6	2.2	6.8	-0.1	-1.3	-1.4	-1.2	-1.3	-1.3	0.2	-1.3	-1.2	-1.6	-1.4	-1.4	-2.6	-1.3	-1.4	-0.5	-1.3	-2.1	-1.0	-2.4	-1.5	-1.8	-1.4
Stomach or abdominal pain in last month	1.5	1.9	4.1	0.7	1.4	1.5	1.4	1.4	1.4	0.3	1.4	2.0	1.3	0.9	1.4	1.8	1.5	1.4	0.0	1.7	1.2	1.4	1.4	1.4	1.4	1.4
Past tobacco smoking	1.5	2.7	6.6	-2.6	-1.9	-1.8	-1.8	-1.6	-1.8	-1.6	-1.8	-1.5	-1.7	-1.3	-1.7	-1.7	-1.9	-1.7	-1.7	-1.8	-1.0	-0.7	-0.8	-1.1	-1.3	-1.7
Sensitivity / hurt feelings	1.4	2.4	5.7	1.3	1.7	1.7	1.8	1.6	1.8	1.0	1.7	1.6	1.6	0.2	1.8	1.3	1.7	1.8	1.2	1.6	1.1	1.4	1.3	2.4	1.4	1.8
Eye problems/disorders: Diabetes related eye disease	1.4	1.5	3.7	-0.4	-1.1	-1.1	-1.1	-1.4	-1.1	-0.4	-1.2	-1.1	-1.4	-1.0	-1.1	-0.7	-1.1	-1.1	-0.8	-1.2	-1.7	-1.9	-1.9	-1.5	-1.6	-1.1
Impedance of leg (right)	1.4	6.6	8.7	1.6	2.7	2.8	2.7	2.8	2.8	2.3	2.8	3.0	2.5	2.5	2.8	2.5	2.7	2.8	2.0	2.8	2.0	2.7	2.4	2.0	2.5	2.8
Maternal smoking around birth	1.4	2.0	4.2	0.9	1.6	1.6	1.5	1.3	1.5	0.1	1.5	1.7	1.3	1.7	1.6	2.1	1.6	1.6	0.5	1.6	0.8	0.7	1.1	1.9	1.2	1.6
Qualifications: CSEs or equivalent	1.4	1.9	3.9	-1.3	-1.2	-1.2	-1.2	-1.5	-1.2	-1.5	-1.4	-2.0	-1.5	-1.2	-1.2	-0.6	-1.2	-1.2	-1.4	-1.2	-1.9	-1.8	-1.7	-0.7	-1.7	-1.2
Forced expiratory volume in 1-second (FEV1), predicted	1.4	3.0	5.1	1.2	1.9	2.1	2.1	1.6	2.1	0.8	1.8	1.9	1.4	1.8	2.1	1.9	1.9	2.1	1.1	2.3	0.3	1.1	0.5	2.1	1.1	2.1
Mouth/teeth dental problems: Mouth ulcers	1.4	2.2	5.7	-2.0	-1.5	-1.5	-1.6	-1.5	-1.6	-1.0	-1.4	-1.2	-1.5	-2.3	-1.5	-1.5	-1.4	-1.5	-2.4	-1.5	-1.1	-0.6	-0.9	-0.4	-1.3	-1.5
Medication: Aspirin	1.4	1.8	6.2	0.6	1.0	1.1	1.0	1.2	1.1	0.7	1.1	1.2	1.6	0.3	1.1	2.0	0.9	1.1	0.7	0.9	2.5	1.3	2.3	1.4	1.9	1.1
Medication: Lansoprazole	1.3	1.5	3.3	0.5	1.1	1.2	1.2	1.4	1.2	1.1	1.3	1.1	1.2	0.8	1.2	1.3	1.3	1.2	0.8	1.2	1.2	1.8	1.5	0.9	1.4	1.2
Impedance of arm (left)	1.3	6.0	10.7	0.4	2.3	2.5	2.3	2.5	2.3	1.1	2.4	3.0	2.5	2.2	2.5	3.3	2.3	2.5	1.0	2.4	2.9	2.8	3.2	2.8	2.8	2.5
Blood clot in the leg (DVT)	1.3	1.7	2.8	1.3	1.3	1.3	1.2	1.5	1.2	1.5	1.4	0.9	1.5	1.1	1.2	1.4	1.3	1.2	1.1	1.3	1.7	1.3	1.6	0.4	1.6	1.2
Glaucoma (self-reported)	1.3	1.5	5.9	0.1	1.2	1.3	1.1	1.3	1.1	0.9	1.4	1.6	1.0	-1.2	1.2	0.4	1.4	1.2	0.3	1.2	0.6	1.9	1.3	2.4	1.1	1.2
Medication: Ibuprofen	1.3	1.6	2.3	0.5	1.4	1.4	1.3	1.3	1.3	0.7	1.3	0.8	1.2	1.4	1.3	1.4	1.4	1.3	1.0	1.3	1.3	1.5	1.4	1.2	1.4	1.3
Number of self-reported non-cancer illnesses	1.3	2.2	5.6	-2.4	-1.6	-1.4	-1.5	-1.4	-1.5	-1.9	-1.4	-2.1	-1.4	-2.2	-1.4	-0.7	-1.5	-1.4	-2.2	-1.5	-0.7	-0.5	-0.5	0.4	-1.1	-1.4
Alcohol intake versus 10 years previously	1.2	1.8	4.1	-1.0	-1.6	-1.5	-1.5	-1.5	-1.4	-1.8	-1.7	-1.2	-1.1	0.2	-1.4	-0.1	-1.7	-1.4	-1.5	-1.2	-0.2	-1.7	-0.5	-2.0	-0.9	-1.4
Birth weight	1.2	2.6	12.8	-1.7	-1.6	-1.5	-1.6	-1.4	-1.6	0.3	-1.5	-3.6	-1.1	-2.5	-1.5	-1.6	-1.6	-1.5	-1.1	-1.9	-0.1	-1.0	-0.3	-1.9	-0.9	-1.5
Handedness (chirality/laterality): Left-handed	1.2	1.5	4.2	-1.6	-1.0	-0.9	-1.0	-1.2	-1.0	-1.9	-1.1	-2.0	-1.2	-1.7	-0.9	-0.5	-1.0	-0.9	-1.3	-1.0	-1.5	-1.1	-0.9	0.7	-1.2	-0.9
Smoking status: Current	1.2	1.9	3.6	-0.6	-1.3	-1.3	-1.2	-1.5	-1.2	-1.2	-1.5	-1.0	-1.5	-0.4	-1.3	-1.1	-1.3	-1.3	-1.5	-1.3	-1.6	-1.9	-1.9	-1.6	-1.6	-1.3
High blood pressure (mother)	1.1	1.5	5.2	1.6	1.1	1.2	1.2	1.4	1.2	2.3	1.3	1.0	1.3	0.7	1.2	0.7	1.1	1.2	1.4	1.2	1.2	1.5	0.9	0.4	1.2	1.2
Commuting to job workplace: Walk	1.1	1.2	2.8	-0.6	-1.1	-1.2	-1.2	-1.3	-1.2	-1.2	-1.3	-0.9	-1.1	-1.0	-1.2	-0.9	-1.2	-1.2	-0.7	-1.2	-0.8	-1.7	-1.0	-0.8	-1.1	-1.2
Wears glasses or contact lenses	1.1	1.2	2.5	-0.6	-0.9	-1.1	-1.1	-1.2	-1.1	-0.5	-1.0	-1.0	-1.3	-1.4	-1.1	-1.1	-0.9	-1.1	-0.4	-1.4	-1.6	-1.2	-1.5	-0.2	-1.4	-1.1
Alzheimer’s Disease (including proxy)	1.0	1.4	4.2	-1.2	-1.1	-1.0	-1.0	-1.2	-1.0	-0.8	-1.1	-1.1	-1.2	-2.1	-1.0	-1.3	-1.0	-1.0	-1.9	-0.9	-1.2	-0.9	-1.1	-1.1	-1.1	-1.0
Type 2 Diabetes (T2D) (2012)	1.0	1.2	3.4	-1.5	-0.6	-0.7	-0.9	-0.9	-0.9	-1.8	-0.6	-1.1	-1.2	-1.8	-0.7	-0.8	-0.5	-0.7	-1.1	-0.7	-1.8	-0.4	-0.9	1.2	-1.2	-0.7
Fed-up feelings	1.0	1.8	4.6	1.0	1.2	1.3	1.2	1.4	1.2	0.3	1.4	1.8	1.4	0.8	1.3	1.5	1.2	1.3	0.7	1.3	1.5	1.5	1.6	2.1	1.5	1.3
Age when periods started (menarche)	1.0	2.4	6.4	1.0	1.5	1.5	1.5	1.6	1.5	2.5	1.5	1.0	1.6	1.2	1.5	1.9	1.4	1.5	1.1	1.3	1.8	1.6	1.7	0.6	1.7	1.5
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	2.9	0.7	1.1	1.1	1.1	1.1	1.1	0.3	1.2	1.7	1.0	0.3	1.2	0.4	1.2	1.2	0.5	1.4	0.4	1.4	0.8	1.2	0.9	1.2
Pain all over the body in last month	1.0	1.1	3.8	-0.1	-1.0	-1.0	-0.9	-1.0	-0.9	-0.1	-1.2	-1.9	-0.9	-1.2	-1.0	-1.4	-1.1	-1.0	-0.5	-0.9	-0.8	-1.3	-1.1	-1.5	-1.0	-1.0
Medication: Ventolin 100micrograms inhaler	1.0	1.3	3.0	-1.6	-1.2	-1.1	-1.1	-1.1	-1.1	-0.8	-1.1	-1.7	-1.1	-1.4	-1.0	-1.4	-1.1	-1.0	-1.4	-0.9	-1.0	-0.7	-0.8	-1.4	-1.0	-1.0
Medication: Blood pressure	1.0	1.8	5.6	0.4	1.2	1.4	1.3	1.4	1.3	0.7	1.4	1.2	1.4	-0.5	1.4	1.5	1.3	1.4	0.6	1.3	1.4	1.7	1.7	2.4	1.5	1.4
Loneliness, isolation	1.0	1.4	2.4	1.5	1.2	1.2	1.2	1.2	1.2	0.6	1.2	1.1	1.4	1.4	1.2	1.0	1.2	1.2	1.0	1.2	1.3	0.8	1.2	0.4	1.3	1.2
Reaction Time	0.9	1.6	3.2	-0.1	-1.5	-1.6	-1.5	-1.3	-1.5	0.1	-1.4	-1.3	-1.1	-0.6	-1.5	-1.2	-1.6	-1.5	-0.0	-1.6	-0.6	-1.5	-1.0	-1.8	-1.1	-1.5
Verbal and Numeric Reasoning (VNR)	0.9	2.1	7.4	-0.5	-1.2	-1.3	-1.2	-1.3	-1.2	0.3	-1.2	-1.0	-1.6	-1.5	-1.3	-2.7	-1.2	-1.3	-0.9	-1.3	-2.2	-0.6	-2.3	-1.4	-1.8	-1.3
Mean Putamen Volume	0.9	1.1	4.5	-1.1	-1.2	-1.1	-1.1	-0.9	-1.1	-1.0	-1.1	-1.0	-0.8	0.7	-1.1	-1.1	-1.1	-1.1	-0.0	-1.3	-0.1	-0.6	-0.2	-2.1	-0.6	-1.1
Worrier / anxious feelings	0.9	1.6	4.3	0.9	0.9	1.0	1.0	1.2	1.1	1.1	1.0	1.8	1.5	1.2	1.1	1.7	0.8	1.1	0.9	1.1	2.1	1.3	1.8	1.0	1.6	1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.1	1.9	0.9	1.0	1.1	1.2	1.0	1.2	0.6	1.0	1.0	1.2	-0.0	1.2	1.4	1.1	1.2	-0.2	1.2	1.2	1.1	1.2	0.9	1.3	1.1
Medication: Allopurinol	0.9	1.2	2.2	1.2	1.1	1.1	1.1	1.1	1.1	1.1	1.0	0.4	1.2	1.5	1.1	1.3	1.0	1.1	1.0	1.1	1.3	1.0	1.0	0.6	1.1	1.1
Medication: Seretide 50 evohaler	0.9	1.1	2.1	1.0	1.1	1.1	1.1	1.0	1.1	0.5	1.1	1.0	1.1	0.2	1.1	0.8	1.1	1.1	0.6	1.1	0.9	0.7	1.1	1.5	1.0	1.1
Had major operations	0.9	1.0	1.9	1.4	1.1	1.1	1.1	1.2	1.1	1.3	1.2	0.9	1.0	-0.1	1.1	-0.0	1.2	1.1	1.1	1.1	0.5	1.3	0.6	0.8	0.9	1.1
Medication: Aspirin	0.9	1.1	4.6	0.6	0.8	0.8	0.8	1.0	0.8	0.7	0.8	0.9	1.3	0.2	0.8	1.7	0.7	0.8	0.8	0.6	2.1	0.9	1.9	1.0	1.6	0.8
Commuting to job workplace: Public transport	0.9	1.1	2.9	-1.1	-0.9	-1.0	-1.1	-1.0	-1.1	-0.1	-1.0	-1.0	-1.1	-1.7	-1.1	-1.2	-0.9	-1.1	-0.9	-1.2	-0.9	-0.7	-0.8	-1.1	-0.9	-1.1
Alzheimer’s Disease (in mother)	0.8	0.9	2.7	-1.5	-1.1	-0.9	-1.0	-1.0	-0.9	-1.2	-1.1	-0.8	-0.8	-1.4	-0.9	-0.4	-1.1	-0.9	-1.6	-0.9	-0.2	-0.6	-0.2	-0.6	-0.5	-0.9
Primary Biliary Cirrhosis	0.8	1.1	4.1	-0.8	-0.7	-0.8	-0.9	-1.0	-0.9	-1.5	-0.7	-0.8	-1.3	-1.0	-0.9	-1.5	-0.6	-0.9	-0.9	-0.7	-2.0	-0.8	-1.6	-0.1	-1.5	-0.9
BMI	0.8	4.8	11.8	-1.0	-2.2	-2.3	-2.1	-2.2	-2.2	-0.3	-2.3	-3.4	-2.0	-1.9	-2.2	-1.9	-2.2	-2.2	-1.5	-2.4	-1.6	-2.5	-2.0	-3.4	-2.0	-2.2
Taking other prescription medications	0.8	1.3	3.2	-1.8	-1.4	-1.2	-1.2	-1.0	-1.2	-1.0	-1.3	-1.0	-0.9	-1.3	-1.2	-0.2	-1.4	-1.2	-1.7	-1.0	0.2	-0.3	0.0	-1.4	-0.5	-1.2
Medication: Levothyroxine sodium	0.8	1.4	2.1	0.4	1.2	1.3	1.3	1.2	1.3	1.0	1.2	0.0	1.2	0.6	1.4	1.0	1.2	1.4	0.5	1.3	1.2	1.5	1.4	1.2	1.3	1.4
Pulse wave reflection index	0.8	1.0	3.8	0.8	-0.9	-1.0	-0.9	-1.0	-0.9	-0.2	-1.1	-1.5	-0.5	0.1	-1.0	-0.4	-1.1	-1.0	0.1	-1.2	0.1	-1.7	-0.7	-2.0	-0.6	-1.0
Intelligence (Savage-Jansen 2018)	0.7	2.2	4.9	-0.3	-1.5	-1.6	-1.4	-1.5	-1.5	-0.0	-1.5	-0.7	-1.7	-0.6	-1.6	-2.1	-1.4	-1.6	-0.7	-1.6	-1.8	-1.1	-2.2	-1.8	-1.8	-1.6
Schizophrenia vs Biploar Disorder	0.7	0.9	2.4	0.6	0.8	0.8	0.8	1.0	0.8	1.2	0.9	1.1	1.0	0.7	0.8	0.3	0.8	0.8	0.9	1.0	1.2	1.5	1.2	-0.6	1.1	0.8
Alzheimer’s Disease (in father)	0.7	0.8	3.4	-0.3	-0.4	-0.5	-0.4	-0.7	-0.4	0.1	-0.5	-0.8	-1.0	-1.6	-0.5	-1.4	-0.3	-0.5	-1.1	-0.4	-1.8	-0.6	-1.7	-0.6	-1.2	-0.5
Breast Cancer	0.7	1.7	5.5	2.0	-0.8	-1.0	-0.6	-1.0	-0.7	1.0	-1.0	-1.7	-0.8	-0.0	-0.9	-1.6	-1.0	-0.9	1.1	-1.0	-1.3	-1.8	-2.3	-2.1	-1.4	-0.9
Bipolar Disorder (2011)	0.7	0.7	4.3	0.4	0.9	0.9	0.9	0.5	0.9	-0.8	0.7	0.2	0.6	0.2	0.9	1.3	0.9	0.9	0.3	0.8	-0.1	-0.3	0.3	2.1	0.4	0.9
Height	0.7	12.6	32.0	2.2	4.2	4.3	4.2	3.2	4.2	0.7	3.8	3.8	3.0	2.5	4.3	4.2	4.2	4.3	2.6	4.5	0.5	1.6	1.6	5.7	2.3	4.3
Vitamin and mineral supplements	0.7	0.9	2.3	1.2	0.9	0.8	0.8	1.0	0.8	0.6	1.0	1.0	1.1	1.4	0.7	0.5	0.8	0.7	1.5	0.7	1.4	0.9	1.2	0.4	1.1	0.7
Severe depression (siblings)	0.7	0.8	2.6	-0.1	-0.7	-0.8	-0.8	-0.9	-0.8	0.1	-0.8	-1.0	-0.8	-1.1	-0.8	-0.7	-0.7	-0.8	-0.8	-0.8	-1.0	-1.0	-1.0	-1.6	-0.9	-0.8
Current tobacco smoking	0.7	1.1	2.6	-0.3	-0.9	-0.9	-0.8	-1.1	-0.9	-1.0	-1.1	-0.5	-1.1	-0.3	-0.9	-0.9	-0.9	-0.9	-1.3	-0.9	-1.3	-1.5	-1.6	-1.2	-1.3	-0.9
Relative age voice broke	0.7	1.0	2.5	1.4	1.1	1.1	1.1	1.1	1.1	1.1	1.1	1.2	1.0	0.6	1.0	0.4	1.1	1.0	1.6	1.0	0.5	1.1	0.5	0.8	0.8	1.0
Multivitamins +/- minerals	0.7	0.9	2.0	-1.1	-0.8	-0.7	-0.7	-1.0	-0.7	-0.5	-1.0	-1.4	-1.0	-1.0	-0.7	-0.6	-0.8	-0.7	-1.4	-0.6	-1.3	-0.8	-1.1	-0.9	-1.0	-0.7
Standing height	0.7	7.0	20.9	1.8	3.1	3.2	3.2	2.1	3.2	-0.1	2.6	2.5	2.1	2.1	3.2	3.4	3.1	3.2	1.1	3.5	0.0	0.6	0.8	4.6	1.5	3.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	3.2	0.5	0.8	0.9	0.9	1.0	0.9	-0.0	0.9	0.7	1.2	0.4	1.0	1.5	0.9	1.0	-0.4	1.0	1.8	1.2	1.7	1.2	1.5	1.0
Forced vital capacity (FVC), Best measure	0.7	2.7	7.0	2.7	2.0	2.0	2.1	1.4	2.0	1.0	1.7	1.4	1.1	1.7	2.0	0.6	2.1	2.0	1.6	2.3	-1.0	0.6	-0.7	0.9	0.4	2.0
Health satisfaction	0.7	0.8	1.5	0.0	0.9	1.0	0.9	1.0	1.0	0.4	1.0	0.5	0.9	0.6	1.1	0.9	1.0	1.1	0.5	1.1	0.8	1.2	1.2	1.1	1.0	1.0
Overall health rating	0.7	1.4	5.1	0.1	0.8	1.0	0.9	1.3	1.0	1.2	1.1	0.4	1.4	-0.4	1.0	1.4	0.9	1.0	0.1	1.0	2.1	1.8	2.3	0.8	1.7	1.0
Qualifications: nursing, teaching	0.7	1.1	3.4	0.6	-1.0	-1.0	-0.8	-1.0	-0.9	-0.2	-1.1	-0.8	-1.0	0.7	-1.0	-1.4	-1.1	-1.0	-0.3	-0.9	-1.0	-1.3	-1.7	-1.9	-1.2	-1.0
Asthma (self-reported)	0.7	1.3	3.5	-1.9	-1.4	-1.3	-1.3	-0.9	-1.3	-1.0	-1.2	-1.2	-0.7	-0.5	-1.2	-0.7	-1.3	-1.2	-1.5	-1.1	0.6	-0.1	0.5	-1.8	-0.2	-1.2
Pain type(s) experienced in last month: Hip pain	0.7	0.9	2.3	0.4	0.8	0.9	0.9	1.1	0.9	0.6	1.1	1.4	1.0	0.8	0.9	0.6	0.9	0.9	0.2	1.1	1.2	1.5	1.2	0.6	1.2	0.9
Ever smoked	0.7	1.2	3.7	1.9	1.4	1.2	1.3	1.0	1.2	1.1	1.2	1.0	1.0	0.9	1.2	1.2	1.4	1.2	0.7	1.3	0.3	0.3	0.1	0.6	0.6	1.2
Myopia	0.7	1.0	2.7	-0.7	-0.6	-0.7	-0.7	-1.0	-0.7	-1.5	-0.9	-1.2	-1.1	-0.8	-0.7	-1.0	-0.7	-0.7	-0.5	-0.9	-1.7	-1.4	-1.5	0.5	-1.4	-0.7
Cholesterol lowering medication	0.7	1.0	4.2	-0.7	-1.1	-1.1	-1.0	-1.1	-1.0	-0.9	-1.2	-2.0	-0.9	-0.9	-1.0	-0.6	-1.2	-1.0	-0.3	-1.2	-0.4	-1.3	-0.7	-0.6	-0.9	-1.0
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	1.7	1.1	0.9	0.9	0.9	1.1	0.9	1.2	1.0	0.6	1.1	0.8	0.9	1.1	0.9	0.9	0.9	1.0	1.3	0.9	1.2	0.1	1.2	0.9
HbA1C	0.6	0.7	1.5	1.1	0.5	0.5	0.6	0.9	0.6	0.3	1.1	1.2	0.8	1.2	0.5	0.5	1.0	0.5	0.9	0.6	1.0	1.0	0.8	0.5	0.9	0.5
Neuroticism (2016)	0.6	0.8	1.9	1.1	0.8	0.8	0.9	0.9	0.9	0.6	0.7	0.5	1.1	0.8	0.9	0.9	0.7	0.9	1.1	0.8	1.4	0.4	1.1	0.4	1.1	0.9
Rheumatoid Arthritis	0.6	0.8	1.6	0.7	0.9	0.8	0.8	1.0	0.8	0.8	1.0	1.1	1.0	0.7	0.8	0.9	0.9	0.8	0.6	0.8	1.2	1.0	1.3	0.9	1.1	0.8
Ever used hormone-replacement therapy (HRT)	0.6	0.7	1.4	-0.3	-0.8	-0.9	-0.9	-1.0	-0.9	-0.6	-0.9	-0.6	-0.8	-1.2	-0.9	-0.8	-0.9	-0.9	-0.7	-0.9	-0.7	-1.1	-0.9	-0.9	-0.8	-0.9
Body mass index (BMI)	0.6	2.4	5.8	-0.9	-1.8	-1.8	-1.7	-1.5	-1.7	-0.5	-1.7	-2.3	-1.3	-1.6	-1.8	-1.2	-1.7	-1.8	-1.4	-1.8	-0.3	-1.4	-0.7	-2.4	-1.0	-1.8
Number of incorrect matches in round	0.6	1.0	1.6	-0.8	-1.2	-1.2	-1.2	-0.9	-1.2	-1.0	-1.0	-0.9	-0.8	-0.7	-1.2	-1.2	-1.1	-1.2	-0.7	-1.2	-0.4	-0.8	-0.3	-1.2	-0.7	-1.2
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.4	0.1	-0.9	-0.9	-0.8	-0.9	-0.8	-0.0	-0.9	-1.5	-0.7	-0.4	-0.9	-0.5	-1.0	-0.9	-0.3	-1.3	-0.5	-1.3	-1.0	-0.3	-0.9	-0.9
Asthma	0.6	1.2	4.0	-1.6	-1.3	-1.2	-1.2	-0.8	-1.2	-0.8	-1.1	-1.1	-0.6	-0.3	-1.2	-0.6	-1.3	-1.2	-1.3	-1.0	0.8	-0.1	0.6	-2.0	-0.1	-1.2
Illnesses of mother	0.6	0.7	1.7	-0.2	-0.7	-0.8	-0.8	-0.9	-0.8	-1.0	-0.8	-0.5	-0.8	0.6	-0.9	-0.5	-0.7	-0.9	-0.5	-0.8	-0.8	-1.3	-1.1	-1.2	-0.9	-0.9
Medication: Paracetamol	0.6	1.0	4.4	-1.4	-1.0	-1.0	-1.1	-1.0	-1.0	-1.6	-1.0	-1.0	-0.8	-1.0	-1.0	-0.6	-1.0	-1.0	-2.1	-0.8	-0.3	-0.6	-0.2	-0.2	-0.6	-1.0
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	3.2	0.6	1.0	1.1	1.1	1.2	1.1	1.7	1.1	0.6	1.1	0.4	1.1	0.7	1.0	1.1	0.9	0.9	1.2	1.8	1.3	0.5	1.3	1.1
Migraine (self-reported)	0.6	0.8	6.5	-1.4	-0.4	-0.4	-0.5	-0.7	-0.5	-2.5	-0.5	-0.2	-0.6	-0.7	-0.4	-0.1	-0.4	-0.4	-1.4	-0.3	-0.7	-0.7	-0.3	1.6	-0.6	-0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.2	-0.9	-0.9	-0.8	-0.8	-0.9	-0.8	-0.7	-0.9	-0.7	-1.0	-0.8	-0.8	-0.7	-0.9	-0.8	-0.9	-0.8	-1.1	-0.6	-1.1	-0.5	-1.0	-0.8
Illnesses of father: Heart disease	0.6	0.8	1.1	0.7	0.9	1.0	0.9	0.9	0.9	0.8	1.0	0.6	0.9	0.6	1.0	1.1	0.9	1.0	0.9	0.8	0.7	1.0	0.9	0.8	0.9	1.0
Tinnitus: Yes, now most or all of the time	0.6	0.7	2.0	0.7	0.7	0.7	0.8	0.9	0.8	1.4	0.8	0.3	0.8	0.5	0.7	0.5	0.7	0.7	1.1	0.7	0.9	1.4	0.7	0.0	0.9	0.7
Average weekly fortified wine intake	0.5	0.6	1.3	0.5	0.6	0.6	0.7	0.8	0.7	0.8	0.7	0.5	0.8	1.0	0.6	0.7	0.5	0.6	1.2	0.5	1.1	1.1	0.8	0.5	0.9	0.6
Chronic bronchitis/emphysema (father)	0.5	0.6	2.8	-1.2	-0.6	-0.5	-0.6	-0.6	-0.6	-0.9	-0.5	-1.0	-0.6	-1.7	-0.5	-0.5	-0.5	-0.5	-1.3	-0.6	-0.6	-0.1	-0.2	0.6	-0.5	-0.5
Qualifications: None of the above	0.5	1.1	4.5	0.5	0.7	0.7	0.6	1.0	0.6	0.7	0.8	0.4	1.2	0.6	0.7	1.5	0.7	0.7	1.3	0.4	2.1	0.8	2.0	1.0	1.5	0.7
Breastfed as a baby	0.5	0.6	3.4	-0.5	0.6	0.7	0.6	0.5	0.6	-0.3	0.7	0.8	0.5	-1.5	0.7	0.3	0.8	0.7	-0.6	0.7	-0.1	0.8	0.7	1.8	0.5	0.7
Chest pain or discomfort	0.5	0.7	3.0	0.5	0.4	0.5	0.5	0.7	0.5	0.5	0.5	0.7	0.9	1.4	0.6	1.3	0.4	0.6	0.6	0.5	1.7	0.3	1.4	-0.0	1.1	0.6
Mood swings	0.5	0.9	3.3	1.8	1.0	0.9	1.0	0.9	0.9	0.8	0.9	0.6	1.1	0.7	0.9	1.0	1.0	0.9	1.2	0.8	1.1	0.1	0.7	0.4	0.9	0.9
Eye problems/disorders: Cataract	0.5	0.6	3.0	-0.8	-0.9	-0.8	-0.8	-0.7	-0.7	-0.5	-0.8	-0.2	-0.6	-0.8	-0.7	-0.8	-0.9	-0.7	-1.7	-0.5	-0.4	-0.0	-0.3	-0.8	-0.4	-0.7
Illnesses of father: None of the above (group 1)	0.5	0.6	1.9	0.9	0.8	0.8	0.9	0.6	0.9	0.1	0.6	0.9	0.7	1.4	0.9	0.6	0.7	0.9	1.0	0.9	0.3	-0.2	0.2	0.4	0.5	0.9
Hearing aid user	0.5	0.6	2.2	1.4	0.8	0.7	0.8	0.6	0.8	0.1	0.6	0.5	0.8	1.5	0.7	0.9	0.7	0.7	1.0	0.8	0.8	-0.1	0.4	0.2	0.6	0.7
Medication: Paracetamol	0.5	0.8	4.1	-1.3	-0.8	-0.8	-0.9	-0.8	-0.9	-1.6	-0.8	-0.8	-0.7	-1.1	-0.8	-0.6	-0.8	-0.8	-2.0	-0.7	-0.2	-0.4	-0.1	0.2	-0.5	-0.8
Commuting to job workplace: Cycle	0.5	0.6	1.3	0.2	0.8	0.8	0.8	0.8	0.8	0.1	0.8	0.7	0.9	0.4	0.8	0.8	0.9	0.8	0.2	0.9	0.9	0.6	1.1	0.7	1.0	0.8
Crohns Disease (2012)	0.4	0.7	1.4	0.3	0.8	0.8	0.7	0.9	0.7	-0.1	0.9	1.0	0.9	0.4	0.8	0.6	0.8	0.8	0.2	1.0	1.0	1.0	1.2	1.2	1.0	0.8
Fasting Glucose	0.4	0.4	1.3	0.8	0.6	0.5	0.4	0.6	0.4	0.7	0.5	0.8	0.7	1.2	0.4	1.0	0.4	0.4	0.7	0.3	1.0	0.3	0.8	0.3	0.7	0.4
LDL Cholesterol	0.4	0.6	2.1	-0.4	-0.9	-0.8	-0.7	-0.8	-0.7	-0.5	-1.0	-0.5	-0.7	0.4	-0.8	-0.8	-1.1	-0.8	-0.3	-0.6	-0.4	-0.7	-0.9	-1.5	-0.7	-0.8
Waist Hip Ratio (WHR)	0.4	1.6	7.6	0.0	0.4	0.5	0.4	0.7	0.5	2.3	0.4	-2.1	1.3	-0.6	0.6	2.1	0.3	0.6	0.3	0.2	2.8	-0.0	2.5	-1.3	1.7	0.6
Hypothyroidism (self reported)	0.4	1.0	3.1	0.6	0.8	0.9	0.9	1.1	0.9	1.6	1.0	0.4	1.1	0.4	0.9	0.4	0.9	0.9	0.9	0.8	1.3	1.8	1.2	0.3	1.2	0.9
Average weekly spirits intake	0.4	0.5	2.0	-1.4	-0.7	-0.7	-0.9	-0.4	-0.8	-1.2	-0.6	-0.3	-0.4	-0.2	-0.8	-0.3	-0.7	-0.8	-0.8	-0.7	0.6	0.3	0.6	-0.1	0.0	-0.8
Systolic blood pressure, automated reading	0.4	1.2	3.4	-1.1	-1.2	-1.3	-1.4	-0.6	-1.4	0.5	-0.8	-0.6	-0.7	-1.8	-1.4	-1.3	-1.1	-1.4	-0.6	-1.5	0.7	1.0	0.5	-1.4	-0.1	-1.4
Medication for hormone replacement therapy	0.4	0.4	1.2	0.1	0.4	0.5	0.6	0.6	0.6	0.4	0.5	0.4	0.7	-0.3	0.6	0.3	0.4	0.6	-0.7	0.8	1.0	1.1	1.0	0.6	0.9	0.6
Hand grip strength (right)	0.4	1.0	6.4	1.9	-0.1	-0.3	-0.0	-0.3	-0.1	0.9	-0.4	-0.6	-0.1	2.5	-0.3	0.3	-0.3	-0.3	1.3	-0.3	-0.1	-1.7	-1.1	-2.4	-0.4	-0.3
Supplements: Glucosamine	0.4	0.5	1.6	-1.3	-0.6	-0.5	-0.5	-0.6	-0.5	-0.8	-0.6	-0.6	-0.7	-1.1	-0.4	-0.8	-0.6	-0.4	-1.1	-0.3	-1.0	0.1	-0.7	-0.0	-0.7	-0.4
Forced vital capacity (FVC)	0.4	1.6	4.5	2.1	1.5	1.5	1.6	0.8	1.5	0.3	1.2	0.9	0.7	1.3	1.5	0.8	1.6	1.5	0.9	1.8	-1.3	-0.5	-1.0	0.9	0.0	1.5
Mouth/teeth dental problems	0.4	0.5	4.0	1.1	0.6	0.5	0.6	0.5	0.6	0.2	0.5	1.0	0.5	2.0	0.5	0.2	0.6	0.5	1.4	0.6	0.3	-0.1	0.0	-0.3	0.4	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.4	4.9	2.2	1.3	1.2	1.4	0.7	1.4	0.6	1.0	0.7	0.5	1.2	1.3	-0.1	1.3	1.3	1.6	1.5	-1.5	-0.3	-1.4	0.3	-0.3	1.3
Headache pain in last month	0.4	0.7	2.7	0.8	0.9	0.8	0.8	0.6	0.8	-0.1	0.7	1.2	0.7	1.6	0.8	1.6	0.8	0.8	0.2	0.8	0.5	0.1	0.5	0.9	0.6	0.8
Chronic bronchitis/emphysema (mother)	0.4	0.5	1.5	-0.1	0.4	0.6	0.6	0.7	0.6	-0.4	0.5	0.7	0.7	1.0	0.7	1.0	0.4	0.7	0.1	0.8	1.0	0.9	1.2	0.7	0.9	0.7
Leg fat percentage (right)	0.4	1.3	6.7	-0.6	-1.2	-1.3	-1.2	-0.9	-1.2	0.4	-1.1	-1.9	-0.7	-0.6	-1.2	-0.7	-1.2	-1.2	-1.0	-1.3	0.4	-0.8	0.0	-2.6	-0.4	-1.2
Number of full brothers	0.4	0.5	3.1	-1.1	-0.4	-0.3	-0.4	-0.6	-0.4	-1.7	-0.4	-0.3	-0.5	-0.4	-0.3	0.2	-0.3	-0.3	-1.8	-0.3	-0.6	-0.9	-0.2	1.4	-0.5	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	1.5	1.1	0.7	0.7	0.7	0.5	0.7	1.2	0.6	-0.5	0.5	-0.0	0.7	0.3	0.6	0.7	1.1	0.5	-0.0	0.2	-0.1	0.3	0.3	0.7
Eye problems/disorders: None of the above	0.4	0.5	3.5	0.7	0.7	0.6	0.6	0.5	0.6	-0.0	0.5	-0.2	0.5	1.9	0.6	0.6	0.6	0.6	1.5	0.5	0.4	-0.0	0.2	0.4	0.4	0.6
Medication for pain relief, constipation, heartburn	0.4	0.7	2.8	0.4	-0.6	-0.7	-0.5	-0.6	-0.6	0.4	-0.6	-0.4	-0.8	0.3	-0.6	-1.2	-0.6	-0.6	0.4	-0.6	-1.2	-0.9	-1.4	-1.7	-1.0	-0.6
Heart disease (mother)	0.4	0.4	2.9	-0.2	0.6	0.6	0.4	0.6	0.5	0.3	0.8	0.8	0.4	-0.5	0.5	0.6	0.7	0.5	0.0	0.4	0.3	1.0	0.8	1.7	0.6	0.5
Leg fat mass (right)	0.4	1.6	4.8	-0.7	-1.4	-1.4	-1.3	-1.2	-1.3	-0.1	-1.4	-2.0	-0.9	-1.1	-1.3	-0.8	-1.4	-1.3	-1.5	-1.3	-0.1	-1.3	-0.4	-2.2	-0.7	-1.3
Alcohol intake frequency.	0.4	1.0	5.2	-1.5	-1.2	-0.9	-0.9	-1.0	-0.9	-2.3	-1.2	-1.3	-0.6	0.3	-0.8	0.5	-1.3	-0.8	-1.2	-0.7	0.2	-0.9	0.2	-0.3	-0.4	-0.8
Comparative height size at age 10	0.4	2.1	8.7	1.1	1.8	1.8	1.8	1.1	1.8	-0.2	1.5	0.3	1.1	0.4	1.8	1.9	1.8	1.8	0.7	1.9	-0.3	-0.2	0.2	3.0	0.6	1.8
Suffer from ‘nerves’	0.4	0.7	2.6	0.7	0.6	0.6	0.6	0.8	0.6	0.5	0.7	1.1	1.0	0.7	0.6	1.0	0.5	0.6	0.2	0.6	1.6	1.2	1.2	0.5	1.2	0.6
Supplements: Vitamin C	0.4	0.4	2.2	-1.1	-0.5	-0.5	-0.6	-0.6	-0.6	-0.6	-0.4	-0.5	-0.6	-1.5	-0.5	-0.1	-0.3	-0.5	-0.9	-0.7	-0.7	-0.5	-0.2	0.7	-0.5	-0.5
Knee pain experienced in last month	0.4	0.6	3.4	-0.3	0.6	0.6	0.6	0.8	0.6	0.3	0.8	0.7	0.7	0.5	0.6	0.5	0.6	0.6	-0.3	0.8	1.1	1.8	1.3	0.6	1.0	0.6
Back pain experienced in last month	0.4	0.6	4.4	-2.1	-0.6	-0.4	-0.6	-0.5	-0.5	-1.2	-0.5	-1.1	-0.5	-0.7	-0.4	0.3	-0.5	-0.4	-1.3	-0.7	-0.3	-0.1	0.3	1.0	-0.3	-0.4
Breast cancer (self-reported)	0.4	0.5	1.3	-1.1	-0.8	-0.7	-0.8	-0.4	-0.8	-0.8	-0.5	0.5	-0.4	-0.1	-0.7	-0.5	-0.7	-0.7	-1.1	-0.6	0.4	0.3	0.4	-0.9	-0.0	-0.7
Financial situation satisfaction	0.4	0.4	1.7	0.2	0.4	0.5	0.5	0.3	0.5	-1.1	0.3	0.6	0.5	1.2	0.6	1.2	0.3	0.6	0.2	0.5	0.6	-0.3	0.7	1.3	0.5	0.6
Medication: Blood pressure	0.4	0.7	3.2	-1.1	-0.9	-0.9	-0.9	-0.7	-0.9	-0.8	-0.9	-1.8	-0.5	-0.9	-0.8	-0.2	-1.0	-0.8	-0.5	-1.1	0.5	-0.5	0.4	-0.5	-0.2	-0.8
Medication: Atorvastatin	0.4	0.5	3.6	-0.9	-0.6	-0.4	-0.4	-0.5	-0.4	-1.1	-0.5	-0.4	-0.2	-1.9	-0.3	-0.4	-0.5	-0.3	-1.3	-0.5	0.0	0.2	0.4	0.7	-0.0	-0.3
Bipolar Disorder or Schizophrenia	0.3	0.8	2.3	0.8	1.0	0.9	0.9	0.9	0.9	0.0	0.9	0.3	0.9	1.5	0.9	1.0	0.9	0.9	0.5	1.1	0.8	0.7	0.8	0.4	0.9	0.9
Body Mass Index (BMI) (2010)	0.3	0.4	1.8	-1.0	-0.6	-0.7	-0.9	-0.5	-0.8	-1.3	-0.5	-0.6	-0.5	-0.6	-0.8	0.1	-0.6	-0.8	-0.3	-0.8	0.2	-0.4	0.3	0.4	-0.2	-0.8
Blood White Count	0.3	2.0	6.4	0.4	1.0	1.1	1.1	1.2	1.1	-0.4	1.1	2.1	1.3	2.5	1.1	2.3	1.0	1.1	0.2	1.2	2.0	1.5	1.9	1.6	1.6	1.1
Hair Pigment	0.3	9.0	20.8	1.1	2.6	2.7	2.6	3.1	2.6	0.8	2.8	4.6	3.0	4.2	2.7	3.6	2.6	2.7	2.2	3.0	3.6	3.7	3.7	2.4	3.4	2.7
Hand grip strength (left)	0.3	0.7	4.4	1.6	0.3	0.1	0.3	-0.1	0.2	0.8	-0.1	-0.8	0.0	2.1	0.1	0.3	0.1	0.1	1.3	0.0	-0.3	-1.4	-1.0	-1.7	-0.3	0.1
Relative age of first facial hair	0.3	0.6	2.2	1.1	0.7	0.6	0.7	0.6	0.7	0.6	0.5	0.5	0.8	1.5	0.6	1.3	0.6	0.6	1.2	0.5	0.7	-0.3	0.6	0.1	0.7	0.6
Leg fat-free mass (left)	0.3	1.5	4.9	-0.6	-1.0	-1.0	-0.9	-1.4	-0.9	-1.6	-1.3	-1.8	-1.2	-1.0	-0.9	-0.6	-1.0	-0.9	-1.4	-0.8	-1.4	-2.2	-1.5	-0.5	-1.4	-0.9
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	2.1	-1.0	-0.5	-0.5	-0.6	-0.2	-0.5	-0.4	-0.3	-0.6	-0.2	-1.5	-0.5	-0.1	-0.4	-0.5	-1.0	-0.4	0.6	0.7	0.7	0.0	0.2	-0.5
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.9	0.0	-0.8	-0.8	-0.7	-0.7	-0.7	-0.6	-0.9	-1.0	-0.5	0.4	-0.7	-0.8	-0.9	-0.7	-0.7	-0.5	-0.2	-1.3	-0.7	-1.4	-0.6	-0.7
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.0	-0.4	0.6	0.6	0.6	0.6	0.6	0.3	0.6	0.5	0.5	0.0	0.7	0.8	0.7	0.7	-0.1	0.5	0.5	0.7	0.7	1.0	0.6	0.7
Leg predicted mass (left)	0.3	1.5	4.8	-0.6	-1.0	-1.0	-0.9	-1.4	-0.9	-1.6	-1.3	-1.8	-1.2	-1.1	-1.0	-0.6	-1.0	-1.0	-1.5	-0.8	-1.4	-2.2	-1.4	-0.5	-1.4	-1.0
Financial difficulties in last 2 years	0.3	0.3	1.4	0.6	0.6	0.7	0.7	0.5	0.7	-0.0	0.6	0.0	0.5	-0.1	0.8	0.5	0.6	0.8	0.0	0.7	0.1	0.3	0.3	1.2	0.4	0.8
Medication: Ramipril	0.3	0.4	2.1	-0.5	0.3	0.4	0.2	0.5	0.3	-0.5	0.4	0.8	0.5	-0.2	0.4	0.8	0.2	0.4	0.1	0.4	1.0	1.1	1.2	1.5	0.7	0.4
Hair/balding pattern: Pattern 3	0.3	0.5	2.6	0.9	0.1	-0.0	0.0	-0.0	-0.0	0.9	0.2	-0.8	-0.3	-1.6	-0.1	-1.3	0.2	-0.1	0.5	-0.2	-1.3	0.2	-1.1	0.6	-0.6	-0.1
Number of live births	0.3	0.4	1.5	0.4	0.6	0.7	0.7	0.6	0.7	0.1	0.6	0.6	0.6	-0.4	0.7	0.8	0.7	0.7	0.2	0.6	0.1	0.3	0.4	1.2	0.4	0.7
Qualifications: A levels/AS levels or equivalent	0.3	0.7	4.5	0.1	-0.2	-0.3	-0.2	-0.6	-0.2	0.4	-0.3	-0.5	-0.9	-0.6	-0.3	-1.3	-0.1	-0.3	-0.2	-0.3	-2.1	-0.7	-1.9	-0.7	-1.3	-0.3
Lung cancer (father)	0.3	0.3	2.2	-1.5	-0.3	-0.2	-0.4	-0.2	-0.3	-0.7	-0.1	-0.2	-0.4	-1.5	-0.2	-0.1	-0.1	-0.2	-0.6	-0.4	-0.6	0.5	0.0	0.8	-0.3	-0.2
Pulse wave Arterial Stiffness index	0.3	0.3	2.3	0.5	0.3	0.2	0.2	0.4	0.2	0.4	0.3	0.3	0.7	0.2	0.2	0.5	0.2	0.2	0.4	0.0	1.5	0.7	1.2	-0.1	0.9	0.2
Exposure to tobacco smoke at home	0.3	0.4	1.4	-0.1	0.6	0.7	0.6	0.6	0.6	-0.0	0.6	0.5	0.6	0.9	0.7	1.2	0.7	0.7	0.4	0.8	0.4	0.5	0.7	0.2	0.6	0.7
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	4.3	-0.0	-0.5	-0.6	-0.6	-0.6	-0.6	-0.2	-0.6	-0.5	-0.6	1.2	-0.7	-0.6	-0.6	-0.7	-0.1	-0.5	-0.3	-0.9	-0.7	-2.1	-0.5	-0.7
Mean time to correctly identify matches	0.3	0.6	1.3	0.3	-0.9	-1.0	-0.9	-0.6	-0.9	0.4	-0.8	-0.8	-0.5	-0.4	-1.0	-0.9	-0.9	-1.0	0.3	-1.1	0.1	-0.9	-0.4	-1.1	-0.5	-1.0
Family relationship satisfaction	0.3	0.4	1.6	1.3	0.5	0.3	0.4	0.3	0.4	1.1	0.3	0.8	0.3	1.2	0.3	0.2	0.3	0.3	1.1	0.2	0.1	-0.3	-0.4	-0.8	0.1	0.3
Leg fat-free mass (right)	0.3	1.5	4.9	-0.6	-1.1	-1.0	-0.9	-1.4	-1.0	-1.7	-1.3	-1.8	-1.2	-1.1	-1.0	-0.5	-1.0	-1.0	-1.5	-0.8	-1.5	-2.2	-1.4	-0.4	-1.4	-1.0
Arm fat percentage (left)	0.3	1.1	3.2	-1.0	-1.2	-1.2	-1.2	-0.9	-1.2	-0.0	-1.1	-1.6	-0.6	-0.9	-1.2	-0.1	-1.3	-1.2	-1.3	-1.3	0.8	-0.7	0.4	-1.8	-0.2	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.7	3.9	2.0	0.5	0.3	0.5	0.1	0.5	1.2	0.3	-0.4	0.0	-0.2	0.3	-0.8	0.5	0.3	1.7	0.3	-1.2	-0.5	-1.4	-0.8	-0.5	0.3
Leg predicted mass (right)	0.3	1.5	5.0	-0.5	-1.0	-1.0	-0.9	-1.4	-0.9	-1.7	-1.3	-1.8	-1.2	-1.2	-0.9	-0.6	-1.0	-0.9	-1.4	-0.8	-1.5	-2.2	-1.5	-0.3	-1.4	-0.9
Guilty feelings	0.3	0.4	1.3	1.1	0.6	0.6	0.7	0.6	0.6	1.1	0.7	1.1	0.6	-0.2	0.6	0.3	0.6	0.6	0.2	0.6	0.4	0.4	0.3	0.7	0.5	0.6
Illnesses of father: High blood pressure	0.3	0.3	1.6	-0.3	0.1	0.2	0.1	0.4	0.2	-0.5	0.3	0.5	0.6	0.6	0.2	0.7	0.1	0.2	0.0	0.4	1.2	1.1	1.2	0.5	0.9	0.2
Alcohol drinker status: Never	0.3	0.4	1.7	-1.3	-0.7	-0.5	-0.6	-0.5	-0.5	-1.0	-0.7	-1.0	-0.3	0.2	-0.5	-0.0	-0.7	-0.5	-0.4	-0.5	0.4	0.1	0.4	-0.2	-0.1	-0.5
Average weekly beer plus cider intake	0.3	0.4	1.3	1.2	0.6	0.7	0.7	0.7	0.7	1.0	0.7	0.4	0.7	0.2	0.7	-0.0	0.6	0.7	0.7	0.9	0.3	0.8	0.3	-0.2	0.5	0.7
Age started oral contraceptive pill	0.3	0.4	1.0	-0.7	-0.6	-0.7	-0.8	-0.4	-0.8	0.3	-0.4	-0.4	-0.7	-0.8	-0.8	-1.0	-0.6	-0.8	-0.1	-0.9	-0.4	0.4	-0.4	-0.9	-0.5	-0.8
Basal cell carcinoma (self-reported)	0.3	0.4	2.2	-1.5	-0.2	-0.1	-0.3	-0.1	-0.2	-1.1	-0.1	0.4	0.1	-0.1	-0.1	0.4	-0.1	-0.1	-0.8	-0.2	0.8	0.7	1.2	0.9	0.5	-0.1
Heart disease (siblings)	0.3	0.4	1.7	-0.6	0.3	0.3	0.2	0.5	0.2	0.4	0.4	0.5	0.5	-1.0	0.3	0.5	0.3	0.3	0.1	0.1	1.1	0.9	1.3	1.0	0.8	0.3
Alcohol drinker status: Previous	0.3	0.3	1.5	-0.5	0.2	0.6	0.6	0.3	0.6	-0.4	0.3	-0.1	0.3	-0.5	0.7	0.2	0.3	0.7	-0.7	0.7	-0.3	0.9	0.3	1.2	0.2	0.7
Age at First Birth	0.2	0.3	1.9	1.0	-0.1	-0.0	0.2	0.0	0.2	1.3	-0.3	-0.9	0.3	0.6	0.1	0.2	-0.3	0.1	0.6	-0.0	0.6	-0.3	-0.1	-1.4	0.2	0.0
Coronary Artery Disease (CAD)	0.2	0.3	1.5	0.3	0.8	0.4	0.2	0.6	0.2	0.2	1.2	0.2	0.2	0.3	0.3	0.2	1.2	0.3	0.5	0.1	-0.1	0.7	0.2	0.9	0.2	0.3
Smoking Status	0.2	0.5	2.3	1.1	-0.2	-0.4	-0.2	-0.6	-0.3	-0.0	-0.3	-0.3	-0.6	-0.1	-0.4	-0.5	-0.1	-0.4	-0.2	-0.4	-1.2	-1.5	-1.5	-0.7	-0.9	-0.4
Allergy or Eczema	0.2	0.6	3.5	0.5	-0.5	-0.6	-0.5	-0.6	-0.5	-0.1	-0.7	-1.3	-0.4	1.0	-0.6	-0.4	-0.7	-0.6	0.1	-0.5	-0.1	-1.5	-0.8	-1.9	-0.6	-0.6
Cardiovascular Disease	0.2	0.6	1.7	0.3	0.7	0.7	0.7	0.6	0.7	0.3	0.7	-0.5	0.8	-1.0	0.7	1.3	0.7	0.7	-0.1	0.7	1.0	0.3	1.1	1.2	0.9	0.7
Respiratory disease	0.2	0.5	3.8	-0.5	-0.7	-0.7	-0.7	-0.1	-0.7	0.6	-0.4	-0.5	-0.0	0.1	-0.7	-0.2	-0.6	-0.7	-0.6	-0.6	1.3	0.6	0.9	-1.9	0.4	-0.7
Lung FVC	0.2	1.1	8.2	1.3	0.0	-0.1	-0.0	-0.6	-0.1	-0.5	-0.2	-0.8	-0.8	-1.1	-0.2	-1.5	0.2	-0.2	0.1	0.0	-2.9	-1.3	-2.5	-0.6	-1.5	-0.2
Pack years adult smoking proportion	0.2	0.3	1.6	-0.8	-0.3	-0.2	-0.3	-0.3	-0.2	-1.3	-0.3	0.0	-0.3	-0.8	-0.2	-0.3	-0.2	-0.2	-1.3	-0.0	-0.6	-0.3	-0.1	0.3	-0.3	-0.2
Townsend deprivation index at recruitment	0.2	0.3	2.1	-0.3	-0.4	-0.4	-0.3	-0.4	-0.3	-1.4	-0.5	-0.5	-0.2	0.4	-0.3	0.2	-0.5	-0.3	-0.9	-0.1	0.2	-0.7	0.0	-0.4	-0.2	-0.3
Sitting height	0.2	1.2	6.6	0.0	0.5	0.5	0.5	-0.4	0.5	-2.0	0.1	0.1	-0.6	-0.1	0.5	0.4	0.6	0.5	-0.9	0.7	-2.6	-1.5	-1.9	2.5	-1.2	0.5
Waist circumference	0.2	0.6	3.1	-0.1	-0.3	-0.3	-0.3	-0.0	-0.3	1.0	-0.2	-1.8	0.4	-1.1	-0.2	0.8	-0.3	-0.2	-0.5	-0.3	1.6	-0.3	1.2	-1.3	0.7	-0.2
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.4	0.0	-0.5	-0.6	-0.6	-0.4	-0.5	-0.5	-0.5	-0.4	-0.2	0.1	-0.6	0.2	-0.6	-0.6	-0.3	-0.6	0.5	-0.6	0.2	-0.6	-0.1	-0.6
Medication: Simvastatin	0.2	0.3	1.4	0.7	0.4	0.5	0.5	0.5	0.5	0.9	0.5	-0.4	0.6	-0.3	0.5	0.9	0.4	0.5	1.2	0.3	0.6	0.1	0.6	0.6	0.5	0.5
Fluid intelligence score	0.2	0.3	1.5	1.1	0.5	0.4	0.5	0.4	0.4	1.2	0.5	0.8	0.2	0.3	0.3	-0.7	0.6	0.3	1.0	0.3	-0.4	0.6	-0.6	0.1	-0.0	0.3
Illnesses of siblings	0.2	0.3	2.1	1.4	0.3	0.1	0.3	0.1	0.2	0.6	0.1	-0.2	0.1	0.6	0.1	-0.7	0.2	0.1	1.1	0.2	-0.4	-0.7	-0.8	-1.0	-0.3	0.1
Arm fat percentage (right)	0.2	0.7	2.2	-0.6	-0.9	-0.8	-0.8	-0.5	-0.8	0.2	-0.8	-1.3	-0.2	-0.6	-0.8	0.2	-0.9	-0.8	-1.0	-0.9	1.1	-0.4	0.8	-1.5	0.2	-0.8
Time employed in main current job	0.2	0.2	0.4	0.2	0.3	0.4	0.5	0.4	0.5	0.6	0.4	0.5	0.4	0.0	0.5	0.3	0.4	0.5	0.5	0.3	0.2	0.5	0.3	0.7	0.3	0.5
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	2.3	-0.8	-0.6	-0.4	-0.4	-0.4	-0.4	-0.6	-0.5	-0.7	-0.4	-1.0	-0.4	-0.3	-0.5	-0.4	-1.5	-0.3	-0.3	-0.1	-0.1	-0.2	-0.3	-0.4
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	4.2	1.5	0.7	0.6	0.8	-0.1	0.7	-0.2	0.3	0.0	-0.1	0.7	0.7	-0.0	0.7	0.7	0.7	0.9	-2.0	-1.4	-1.9	0.2	-0.9	0.7
Happiness	0.2	0.2	1.1	0.6	0.2	0.2	0.2	0.4	0.2	0.0	0.4	1.1	0.4	0.6	0.2	0.2	0.3	0.2	0.7	0.3	0.6	0.4	0.5	0.2	0.5	0.2
Noisy workplace	0.2	0.2	2.1	-0.9	-0.4	-0.4	-0.4	-0.3	-0.4	-0.6	-0.3	-0.5	-0.3	-0.5	-0.4	0.1	-0.4	-0.4	-1.4	-0.4	0.2	0.0	0.2	0.0	-0.1	-0.4
Mouth/teeth dental problems: Dentures	0.2	0.3	1.4	-1.2	-0.5	-0.4	-0.5	-0.3	-0.5	-0.8	-0.3	-0.7	-0.4	-0.9	-0.4	0.3	-0.5	-0.4	-0.0	-0.5	-0.1	0.2	0.2	0.7	-0.2	-0.4
Medication: Cholesterol lowering	0.2	0.3	3.9	-0.2	-0.3	-0.2	-0.2	-0.2	-0.2	0.2	-0.2	-0.4	-0.2	-2.0	-0.2	-0.3	-0.2	-0.2	-0.6	-0.3	-0.5	-0.0	-0.1	0.7	-0.3	-0.2
Depression (self-reported)	0.2	0.2	1.9	-0.6	-0.3	-0.2	-0.2	-0.4	-0.2	-1.0	-0.3	-0.4	-0.2	-0.8	-0.2	0.1	-0.3	-0.2	-1.4	-0.1	-0.2	-0.0	-0.1	-0.0	-0.2	-0.2
Length of working week for main job	0.2	0.2	1.1	0.8	0.4	0.3	0.4	0.1	0.4	0.8	0.1	-0.2	0.2	1.0	0.3	0.8	0.3	0.3	0.4	0.3	0.1	-0.7	-0.3	-0.8	0.0	0.3
Birth weight of first child	0.2	0.4	2.8	0.7	-0.2	-0.3	-0.2	-0.3	-0.2	1.1	-0.4	-1.4	-0.1	0.5	-0.3	-0.6	-0.4	-0.3	0.4	-0.6	0.3	-0.8	-0.3	-1.7	-0.2	-0.3
Arm fat-free mass (right)	0.2	0.8	3.4	0.1	-0.4	-0.4	-0.3	-0.9	-0.4	-1.0	-0.7	-1.3	-0.8	-1.0	-0.4	-0.6	-0.4	-0.4	-0.6	-0.2	-1.7	-1.8	-1.5	-0.3	-1.2	-0.4
Wheeze or whistling in the chest in last year	0.2	0.3	1.8	-0.3	0.2	0.3	0.2	0.4	0.2	0.5	0.3	0.8	0.4	0.1	0.3	1.3	0.3	0.3	-0.1	0.1	0.8	0.5	1.0	0.5	0.6	0.3
Age at first live birth	0.2	0.3	1.6	1.3	0.5	0.3	0.4	0.1	0.4	1.1	0.3	0.1	0.1	0.3	0.3	-0.4	0.4	0.3	0.7	0.5	-0.6	-0.5	-0.8	-0.9	-0.2	0.3
Pulse wave peak to peak time	0.2	0.2	2.3	-0.3	0.0	0.0	0.0	-0.2	0.0	-0.3	-0.1	-0.1	-0.5	-0.0	0.1	-0.3	0.1	0.1	-0.2	0.2	-1.5	-0.6	-1.1	0.4	-0.8	0.1
Shortness of breath walking on level ground	0.2	0.2	0.8	-0.7	-0.5	-0.4	-0.4	-0.3	-0.4	-0.2	-0.4	-0.7	-0.1	-0.8	-0.3	0.0	-0.4	-0.3	-0.5	-0.4	0.4	-0.3	0.6	-0.9	0.1	-0.3
Angina (self-reported)	0.2	0.2	1.5	0.3	-0.1	0.1	0.1	0.2	0.1	0.5	-0.1	-0.2	0.5	0.6	0.1	1.0	-0.1	0.1	0.4	-0.1	1.2	0.0	0.9	-0.4	0.6	0.1
Age at last live birth	0.2	0.3	1.2	0.4	-0.0	-0.1	0.0	-0.3	-0.0	0.5	-0.2	-0.6	-0.4	-0.1	-0.1	-0.7	-0.1	-0.1	-0.0	0.1	-1.0	-0.8	-1.1	-1.0	-0.7	-0.1
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.9	-0.6	-0.4	-0.5	-0.5	-0.4	-0.5	-0.1	-0.4	-0.0	-0.5	-0.4	-0.5	-0.9	-0.4	-0.5	0.1	-0.4	-0.5	-0.3	-0.4	-0.7	-0.5	-0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	2.1	0.3	0.4	0.3	0.2	0.2	0.2	0.2	0.3	-0.3	0.1	-1.0	0.3	0.3	0.3	0.3	-0.1	0.2	-0.4	-0.1	-0.1	1.5	-0.1	0.3
Osteoarthritis (self-reported)	0.2	0.3	1.9	-1.1	-0.0	0.1	-0.1	0.3	-0.0	-0.2	0.2	-0.1	0.1	-0.8	0.0	-0.2	0.0	0.0	-0.6	-0.0	0.6	1.4	0.9	0.8	0.5	0.0
Whole body water mass	0.2	0.9	4.5	0.1	-0.5	-0.5	-0.4	-1.0	-0.4	-1.4	-0.8	-1.4	-0.8	-0.7	-0.5	-0.3	-0.5	-0.5	-0.9	-0.3	-1.5	-2.1	-1.5	-0.1	-1.2	-0.5
Supplements: Fish oil (including cod liver oil)	0.2	0.2	1.2	0.2	0.2	0.2	0.2	0.4	0.2	0.4	0.3	1.1	0.4	0.4	0.2	0.2	0.2	0.2	-0.2	0.3	0.8	0.7	0.7	0.3	0.6	0.2
High cholesterol (Self-reported)	0.2	0.3	1.2	-0.1	0.4	0.5	0.4	0.5	0.4	0.2	0.4	-0.3	0.5	-0.9	0.5	0.6	0.4	0.5	0.0	0.4	0.5	0.7	0.7	1.1	0.5	0.5
Medication: Bendroflumethiazide	0.2	0.3	1.3	0.6	0.6	0.7	0.7	0.5	0.7	0.1	0.6	0.4	0.6	-0.3	0.7	0.3	0.6	0.7	0.3	0.7	0.2	0.3	0.4	1.1	0.4	0.7
Leg fat percentage (left)	0.2	0.9	5.0	-0.4	-1.0	-1.0	-1.0	-0.6	-1.0	0.5	-0.9	-1.6	-0.4	-0.5	-1.0	-0.2	-1.0	-1.0	-0.8	-1.1	0.8	-0.6	0.4	-2.2	-0.1	-1.0
Fractured/broken bones in last 5 years	0.2	0.3	0.9	0.9	0.7	0.6	0.6	0.4	0.6	0.0	0.6	-0.1	0.3	0.4	0.6	0.4	0.7	0.6	0.8	0.6	-0.3	-0.2	-0.3	0.5	0.1	0.6
Ever depressed for a whole week	0.2	0.2	1.3	0.6	-0.5	-0.5	-0.5	-0.4	-0.5	-0.1	-0.5	-0.2	-0.2	0.3	-0.5	-0.1	-0.5	-0.5	-0.3	-0.4	0.2	-0.6	-0.2	-1.1	-0.2	-0.5
Unable to work because of sickness or disability	0.2	0.3	2.5	1.4	0.1	0.1	0.2	0.3	0.2	0.5	0.1	-0.4	0.4	0.8	0.1	0.0	0.1	0.1	0.7	0.3	0.7	-0.0	0.2	-1.6	0.4	0.1
Pain experienced in last month	0.2	0.3	1.2	0.3	-0.1	-0.2	-0.2	-0.4	-0.2	-0.8	-0.3	-0.7	-0.4	-0.8	-0.2	-0.7	-0.1	-0.2	0.4	-0.2	-1.1	-1.1	-0.9	0.2	-0.7	-0.2
Pack years of smoking	0.2	0.3	2.0	-1.0	-0.3	-0.2	-0.3	-0.3	-0.3	-1.4	-0.2	0.2	-0.3	-0.8	-0.2	-0.4	-0.1	-0.2	-1.3	-0.0	-0.5	-0.1	0.1	0.4	-0.2	-0.2
Leg fat mass (left)	0.2	1.0	3.3	-0.4	-1.1	-1.0	-1.0	-0.9	-1.0	0.1	-1.0	-1.8	-0.6	-0.9	-1.0	-0.3	-1.0	-1.0	-1.1	-1.0	0.2	-1.2	-0.1	-1.8	-0.4	-1.0
Schizophrenia (2018)	0.1	0.3	1.0	-0.8	-0.5	-0.4	-0.4	-0.4	-0.4	-0.9	-0.5	-0.8	-0.4	0.4	-0.4	-0.4	-0.5	-0.4	-1.0	-0.1	0.0	0.2	-0.0	-0.8	-0.2	-0.4
Major Depression (MDD)	0.1	0.2	0.9	-0.3	-0.0	-0.0	-0.1	-0.2	-0.1	-0.6	-0.2	-0.6	-0.3	-1.0	-0.1	-0.6	-0.1	-0.1	-0.8	-0.1	-0.5	-0.2	-0.2	0.7	-0.3	-0.1
Lupus	0.1	0.1	0.3	-0.6	-0.4	-0.3	-0.3	-0.3	-0.3	-0.3	-0.3	-0.3	-0.4	-0.3	-0.3	-0.5	-0.3	-0.3	0.1	-0.1	-0.6	0.1	-0.5	-0.6	-0.4	-0.3
Schizophrenia (2014)	0.1	0.2	1.6	0.2	0.1	0.1	0.1	0.3	0.1	0.0	0.1	-0.1	0.3	1.2	0.1	-0.1	0.0	0.1	-0.1	0.5	0.8	0.8	0.5	-1.3	0.5	0.1
Blood Red Count	0.1	0.6	3.3	-0.6	0.4	0.4	0.4	-0.2	0.4	-1.8	0.1	0.7	-0.3	-0.7	0.4	0.3	0.4	0.4	-1.0	0.6	-1.3	-0.6	-1.1	1.4	-0.6	0.4
Systolic Blood Pressure	0.1	0.4	1.8	-0.6	-0.3	-0.3	-0.4	0.2	-0.3	0.4	-0.0	-0.2	0.2	-1.1	-0.3	0.2	-0.3	-0.3	-0.4	-0.4	1.3	1.3	1.3	-0.0	0.7	-0.3
Number of treatments/medications taken	0.1	0.3	1.2	-1.1	-0.2	0.0	-0.1	0.1	-0.0	-0.7	0.0	-0.2	0.1	-0.7	0.0	0.7	-0.1	0.0	-0.8	0.0	0.8	0.8	0.9	0.5	0.4	0.0
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	1.1	-0.7	-0.5	-0.3	-0.3	-0.2	-0.3	-1.1	-0.3	-0.6	-0.2	-0.5	-0.3	-0.3	-0.4	-0.3	-0.8	-0.2	0.0	0.4	0.2	0.2	-0.1	-0.3
Angina	0.1	0.2	1.1	0.2	-0.3	-0.2	-0.1	0.0	-0.1	0.4	-0.3	-0.4	0.3	0.4	-0.1	0.6	-0.3	-0.1	0.3	-0.4	1.0	-0.1	0.7	-0.6	0.5	-0.1
Medication: Co-codamol	0.1	0.1	0.4	-0.5	-0.4	-0.3	-0.3	-0.0	-0.3	0.2	-0.2	-0.1	-0.0	0.2	-0.3	-0.2	-0.4	-0.3	0.4	-0.5	0.6	0.4	0.5	0.0	0.2	-0.3
Trunk fat percentage	0.1	0.4	2.3	0.2	0.3	0.3	0.3	0.5	0.3	0.9	0.3	-0.2	0.7	-0.1	0.4	1.3	0.3	0.4	-0.3	0.3	1.5	0.5	1.4	-0.4	1.0	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.6	0.4	-0.0	-0.0	0.0	0.0	0.0	-0.0	0.0	0.1	0.3	-0.5	0.0	0.2	0.0	0.0	-0.8	0.2	0.6	-0.1	0.5	-0.6	0.4	0.0
High blood pressure	0.1	0.3	3.3	-1.0	-0.3	-0.2	-0.3	-0.2	-0.3	-0.5	-0.2	-1.1	-0.1	-1.8	-0.2	0.3	-0.3	-0.2	-0.7	-0.4	0.2	0.2	0.5	0.8	0.1	-0.2
Medication: Atenolol	0.1	0.2	1.3	-0.8	-0.2	-0.1	-0.2	-0.1	-0.2	-0.6	-0.3	-1.1	0.0	-0.5	-0.1	0.5	-0.3	-0.1	-0.3	-0.4	0.4	-0.1	0.6	0.2	0.2	-0.1
Nervous feelings	0.1	0.3	2.2	0.3	-0.1	-0.1	-0.0	0.2	0.0	0.7	-0.0	0.5	0.5	-0.1	-0.0	0.3	-0.1	-0.0	-0.3	0.0	1.5	0.9	1.1	-0.4	0.8	-0.0
Hearing difficulty/problems with background noise	0.1	0.2	0.7	-0.1	0.4	0.4	0.4	0.4	0.4	0.1	0.5	0.8	0.4	-0.2	0.4	-0.0	0.4	0.4	-0.6	0.4	0.6	0.8	0.5	0.9	0.5	0.4
Had other major operations	0.1	0.2	0.6	-0.8	-0.3	-0.3	-0.4	-0.1	-0.4	0.1	-0.2	-0.3	-0.0	-0.4	-0.4	0.0	-0.4	-0.4	-0.3	-0.5	0.8	0.1	0.7	-0.4	0.3	-0.4
Allergy	0.1	0.2	1.6	-0.2	0.4	0.4	0.3	0.1	0.3	-0.0	0.4	0.9	-0.1	-0.5	0.3	0.2	0.5	0.3	0.3	0.2	-0.7	0.3	-0.3	1.3	-0.1	0.3
Weight	0.1	0.4	1.9	-0.2	-0.5	-0.5	-0.5	-0.7	-0.5	-0.6	-0.7	-1.4	-0.4	-0.7	-0.5	0.2	-0.5	-0.5	-1.1	-0.4	-0.4	-1.3	-0.4	-0.6	-0.5	-0.5
Trunk fat-free mass	0.1	0.6	3.6	0.2	-0.2	-0.2	-0.1	-0.7	-0.1	-1.4	-0.5	-1.0	-0.6	-0.4	-0.1	-0.1	-0.2	-0.1	-0.6	0.1	-1.5	-1.9	-1.3	0.5	-1.0	-0.1
Hip circumference	0.1	0.2	1.3	-0.6	-0.4	-0.4	-0.4	-0.4	-0.4	-0.3	-0.3	-0.8	-0.3	-1.1	-0.4	-0.1	-0.3	-0.4	-1.1	-0.3	-0.2	-0.4	-0.0	-0.0	-0.2	-0.4
Prospective memory result	0.1	0.1	0.7	-0.6	-0.1	-0.1	-0.2	-0.2	-0.2	-0.8	-0.1	-0.1	-0.2	-0.5	-0.1	0.3	-0.1	-0.1	-0.1	-0.1	-0.4	-0.4	-0.1	0.6	-0.3	-0.1
Arm fat mass (right)	0.1	0.4	1.6	-0.3	-0.6	-0.6	-0.6	-0.5	-0.5	0.1	-0.6	-1.3	-0.2	-0.6	-0.5	0.3	-0.6	-0.5	-1.0	-0.5	0.5	-0.8	0.3	-1.1	-0.0	-0.5
Trunk predicted mass	0.1	0.5	3.2	0.3	-0.1	-0.1	0.0	-0.6	-0.0	-1.4	-0.4	-0.9	-0.5	-0.3	-0.0	0.0	-0.1	-0.0	-0.5	0.2	-1.3	-1.8	-1.1	0.6	-0.8	-0.0
Hair/balding pattern: Pattern 4	0.1	0.3	2.0	-0.4	0.3	0.4	0.3	-0.0	0.3	-0.5	0.2	0.9	-0.0	-0.6	0.4	0.4	0.3	0.4	-1.0	0.6	-0.6	-0.5	-0.2	1.4	-0.2	0.4
Peak expiratory flow (PEF)	0.1	0.3	2.8	0.5	0.2	0.1	0.2	-0.3	0.2	0.1	-0.0	0.3	-0.5	-0.4	0.1	-0.6	0.2	0.1	-0.2	0.3	-1.7	-0.7	-1.5	0.2	-0.9	0.1
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.7	-0.2	-0.1	-0.0	-0.1	0.0	-0.0	-0.6	-0.0	0.5	0.1	0.9	-0.0	0.4	-0.0	-0.0	-0.2	0.1	0.4	-0.1	0.5	-0.6	0.3	-0.0
Loud music exposure frequency	0.1	0.1	0.6	0.7	-0.1	-0.1	0.0	-0.2	0.0	0.1	-0.2	-0.8	-0.1	0.6	-0.0	0.6	-0.2	-0.0	-0.1	-0.0	-0.2	-0.8	-0.6	0.0	-0.4	-0.0
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.8	0.1	0.2	0.2	0.1	-0.1	0.1	0.0	0.1	0.1	-0.1	-0.9	0.1	-0.1	0.2	0.1	-0.3	0.2	-0.6	-0.4	-0.4	0.3	-0.3	0.1
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.2	0.2	0.2	0.2	0.2	0.2	0.2	0.5	0.2	-0.4	0.3	-0.2	0.2	0.0	0.2	0.2	-0.3	0.3	0.2	0.4	0.2	0.0	0.3	0.2
Gout (self-reported)	0.1	0.2	0.6	0.7	0.4	0.4	0.4	0.2	0.4	0.7	0.2	-0.8	0.3	0.4	0.4	0.2	0.3	0.4	-0.1	0.5	0.2	-0.2	-0.1	-0.5	0.2	0.4
Medication: Amlodipine	0.1	0.2	1.6	-0.6	-0.3	-0.2	-0.3	-0.3	-0.2	-0.3	-0.3	-0.9	-0.3	-1.3	-0.2	0.2	-0.3	-0.2	-0.7	-0.2	-0.2	-0.2	-0.1	0.5	-0.3	-0.2
High blood pressure (siblings)	0.1	0.2	0.5	-0.6	-0.5	-0.4	-0.3	-0.5	-0.3	-0.5	-0.6	-0.2	-0.5	0.2	-0.3	0.5	-0.6	-0.3	-0.7	-0.3	-0.4	-0.4	-0.5	-0.3	-0.5	-0.3
Body fat percentage	0.1	0.4	1.9	-0.3	-0.5	-0.5	-0.5	-0.2	-0.5	0.6	-0.4	-1.0	0.0	-0.5	-0.5	0.4	-0.5	-0.5	-0.8	-0.5	1.1	-0.2	0.8	-1.4	0.4	-0.5
Qualifications: College or University degree	0.1	0.3	1.6	0.1	-0.5	-0.4	-0.3	-0.5	-0.4	0.2	-0.5	-0.4	-0.5	0.2	-0.4	-0.7	-0.5	-0.4	-0.2	-0.4	-0.8	-0.4	-0.9	-1.2	-0.6	-0.4
Emphysema/chronic bronchitis	0.1	0.1	0.8	0.4	-0.2	-0.1	-0.1	-0.2	-0.1	-0.3	-0.1	-0.6	-0.1	-0.9	-0.1	-0.2	-0.1	-0.1	-0.4	0.0	-0.4	-0.5	-0.2	0.2	-0.2	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.3	0.0	0.0	0.0	0.0	0.1	0.0	0.4	0.0	-0.4	0.2	-0.4	0.1	0.6	0.0	0.1	-0.1	-0.1	0.6	-0.2	0.6	0.0	0.3	0.1
Whole body fat mass	0.1	0.3	1.5	-0.2	-0.5	-0.5	-0.4	-0.4	-0.4	0.1	-0.5	-1.2	-0.1	-0.6	-0.4	0.3	-0.5	-0.4	-1.0	-0.4	0.5	-0.7	0.3	-1.1	0.0	-0.4
Arm predicted mass (right)	0.1	0.6	3.3	0.3	-0.3	-0.3	-0.2	-0.8	-0.2	-0.9	-0.6	-1.2	-0.6	-0.7	-0.2	-0.4	-0.2	-0.2	-0.5	-0.0	-1.6	-1.8	-1.4	-0.1	-1.1	-0.2
Commuting to job workplace: Car/motor vehicle	0.1	0.2	0.5	0.7	0.3	0.4	0.4	0.4	0.4	0.4	0.4	0.2	0.3	0.6	0.4	-0.2	0.4	0.4	0.7	0.5	-0.2	0.3	-0.1	-0.3	0.2	0.4
Hypertension (Self-reported)	0.1	0.2	2.1	-0.7	-0.1	-0.0	-0.1	-0.0	-0.1	-0.2	0.0	-0.9	0.1	-1.5	-0.0	0.5	-0.0	-0.0	-0.4	-0.2	0.4	0.3	0.6	0.7	0.2	-0.0
Whole body fat-free mass	0.1	0.8	4.1	0.0	-0.5	-0.5	-0.4	-1.0	-0.4	-1.4	-0.8	-1.3	-0.8	-0.7	-0.4	-0.3	-0.5	-0.4	-0.8	-0.2	-1.5	-2.0	-1.4	-0.0	-1.1	-0.4
Long-standing illness, disability or infirmity	0.1	0.2	0.6	-0.6	-0.6	-0.5	-0.5	-0.3	-0.5	-0.2	-0.5	-0.6	-0.3	-0.4	-0.5	0.2	-0.5	-0.5	-0.8	-0.5	0.1	0.2	0.1	-0.7	-0.1	-0.5
Ever had bowel cancer screening	0.1	0.1	1.2	-0.8	0.1	0.0	-0.1	-0.1	-0.1	-0.0	0.1	-0.3	-0.2	-1.1	-0.0	-0.0	0.2	-0.0	-0.7	0.0	-0.3	-0.1	0.2	0.3	-0.1	-0.0
Medication for cholesterol	0.1	0.2	2.0	0.1	0.1	-0.0	-0.0	-0.1	-0.1	-0.3	0.0	1.4	-0.3	0.7	-0.1	-0.2	0.1	-0.1	-0.0	0.1	-0.8	-0.3	-0.6	-0.1	-0.4	-0.1
Mineral and other dietary supplements	0.1	0.1	0.7	0.8	-0.0	-0.1	-0.0	-0.1	-0.1	0.1	-0.1	-0.7	-0.0	0.4	-0.1	-0.0	-0.1	-0.1	0.8	-0.1	-0.1	-0.7	-0.4	-0.6	-0.2	-0.1
Arm fat mass (left)	0.1	0.5	2.2	-0.5	-0.8	-0.7	-0.7	-0.7	-0.7	-0.2	-0.8	-1.5	-0.4	-0.8	-0.7	0.1	-0.8	-0.7	-1.1	-0.7	0.4	-0.8	0.2	-1.1	-0.2	-0.7
Average weekly champagne plus white wine intake	0.1	0.1	0.7	-0.0	0.0	0.2	0.2	0.3	0.3	0.8	0.1	0.4	0.3	-0.4	0.3	-0.1	0.0	0.3	0.3	0.2	0.3	0.8	0.3	0.1	0.3	0.3
Miserableness	0.1	0.1	0.9	0.6	0.2	0.2	0.3	0.2	0.3	-0.4	0.2	0.1	0.3	0.9	0.3	0.4	0.2	0.3	0.3	0.3	0.4	0.0	0.1	-0.2	0.2	0.3
Basal metabolic rate	0.1	0.6	3.6	0.0	-0.5	-0.4	-0.3	-0.9	-0.4	-1.2	-0.7	-1.3	-0.7	-0.6	-0.4	-0.1	-0.4	-0.4	-0.9	-0.2	-1.2	-1.9	-1.1	-0.2	-0.9	-0.4
Arm fat-free mass (left)	0.1	0.4	2.5	0.4	-0.2	-0.2	-0.1	-0.6	-0.1	-0.9	-0.4	-1.0	-0.5	-0.6	-0.2	-0.3	-0.1	-0.2	-0.4	0.1	-1.3	-1.6	-1.2	-0.2	-0.8	-0.2
Diastolic blood pressure, automated reading	0.1	0.3	1.7	-0.7	-0.1	-0.1	-0.3	0.2	-0.2	0.2	0.2	0.5	0.1	-1.0	-0.2	0.1	0.0	-0.2	-0.6	-0.2	0.6	1.3	0.9	0.5	0.5	-0.2
Vascular/heart problems diagnosed by doctor	0.1	0.2	2.1	0.4	0.1	0.0	0.1	0.1	0.1	0.1	0.1	1.0	-0.1	1.5	0.0	-0.6	0.1	0.0	0.2	0.3	-0.5	0.1	-0.6	-0.6	-0.3	0.0
Arm predicted mass (left)	0.1	0.4	2.4	0.5	-0.1	-0.1	0.1	-0.5	0.0	-0.8	-0.3	-0.9	-0.4	-0.4	-0.0	-0.1	-0.0	-0.0	-0.3	0.2	-1.2	-1.5	-1.1	-0.0	-0.7	-0.0
Blood Eosinophil Count	0.0	0.1	0.7	0.1	0.0	0.1	0.1	0.1	0.1	-0.1	0.1	0.4	0.2	0.2	0.1	0.8	0.1	0.1	-0.1	0.1	0.4	0.3	0.4	0.2	0.3	0.1
Blood Platelet Count	0.0	0.3	1.6	0.1	-0.4	-0.4	-0.2	-0.4	-0.2	-0.4	-0.4	0.5	-0.5	1.2	-0.3	-0.4	-0.3	-0.3	0.9	-0.1	-0.6	-0.5	-1.0	-1.0	-0.6	-0.3
Trunk fat mass	0.0	0.2	0.8	-0.0	-0.1	0.0	-0.0	-0.0	0.0	0.2	-0.1	-0.7	0.3	-0.4	0.0	0.9	-0.1	0.0	-0.7	0.1	0.8	-0.3	0.7	-0.4	0.4	0.0
Ever taken oral contraceptive pill	0.0	0.0	0.2	0.3	0.1	0.1	0.1	-0.0	0.1	0.2	0.1	0.4	-0.0	-0.3	0.0	0.1	0.1	0.0	-0.3	0.1	-0.2	-0.5	-0.3	0.3	-0.2	0.0
Irritability	0.0	0.0	0.1	0.3	0.1	0.1	0.1	0.1	0.1	-0.3	0.1	-0.1	0.1	0.2	0.1	-0.0	0.2	0.1	0.2	0.0	0.0	-0.2	0.1	0.1	0.1	0.1

Hub : Genes

LEKR1

Models

Trait associations