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Prostate Cancer
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chr2:10,016,627-11,619,674
Best TWAS P=2.75e-11 · Best GWAS P=8.09e-12 conditioned to 0.00857
10M
10.2M
10.4M
10.6M
10.8M
11M
11.2M
11.4M
11.6M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
CommonMind
Brain Pre-frontal Cortex
NOL10
0.10
0.06
lasso
7
0.07
8.9e-09
-6.6
-6.7
2.7e-11
0.78
0.05
0.95
TRUE
4
GTEx
Testis
NOL10
0.51
0.59
lasso
2
0.58
2.0e-31
-5.8
-5.8
8.4e-09
0.79
0.92
0.08
FALSE
1
CommonMind
Brain Pre-frontal Cortex
ATP6V1C2
0.21
0.17
lasso
8
0.20
1.8e-23
-4.7
5.5
4.8e-08
-0.75
0.87
0.13
FALSE
3
GTEx
Skin Sun Exposed Lower leg
NOL10
0.13
0.00
lasso
4
0.00
2.2e-01
4.1
5.3
9.0e-08
-0.61
0.03
0.94
FALSE
5
GTEx
Thyroid
NOL10
0.14
0.08
enet
17
0.09
4.4e-07
-5.8
-5.1
3.0e-07
0.71
0.49
0.51
FALSE