Best TWAS P=2.75e-11 · Best GWAS P=8.09e-12 conditioned to 0.00857
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ATP6V1C2 | 0.21 | 0.17 | lasso | 8 | 0.20 | 1.8e-23 | -4.7 | 5.5 | 4.8e-08 | -0.75 | 0.87 | 0.13 | FALSE |
| 2 | CommonMind | Brain Pre-frontal Cortex | NOL10 | 0.10 | 0.06 | lasso | 7 | 0.07 | 8.9e-09 | -6.6 | -6.7 | 2.7e-11 | 0.78 | 0.05 | 0.95 | TRUE |
| 3 | GTEx | Skin Sun Exposed Lower leg | NOL10 | 0.13 | 0.00 | lasso | 4 | 0.00 | 2.2e-01 | 4.1 | 5.3 | 9.0e-08 | -0.61 | 0.03 | 0.94 | FALSE |
| 4 | GTEx | Testis | NOL10 | 0.51 | 0.59 | lasso | 2 | 0.58 | 2.0e-31 | -5.8 | -5.8 | 8.4e-09 | 0.79 | 0.92 | 0.08 | FALSE |
| 5 | GTEx | Thyroid | NOL10 | 0.14 | 0.08 | enet | 17 | 0.09 | 4.4e-07 | -5.8 | -5.1 | 3.0e-07 | 0.71 | 0.49 | 0.51 | FALSE |