TWAS hub - NOL10

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0970	0.0240	5.4e-07	0.065	0.062	0.068	0.064	0.069	2.4e-08	5.2e-08	1.2e-08	2.8e-08	8.9e-09
2	GTEx	Artery Tibial	0.1288	0.0497	4.8e-03	0.032	NA	0.028	NA	0.040	1.4e-03	NA	2.5e-03	NA	4.0e-04
3	GTEx	Nerve Tibial	0.2084	0.0514	1.3e-05	0.094	NA	0.073	NA	0.079	3.6e-07	NA	7.7e-06	NA	3.1e-06
4	GTEx	Skin Sun Exposed Lower leg	0.1280	0.0430	6.6e-04	0.004	NA	0.002	NA	0.002	1.3e-01	NA	2.2e-01	NA	2.2e-01
5	GTEx	Spleen	0.3660	0.1060	2.7e-03	0.229	NA	0.073	NA	0.184	1.4e-06	NA	6.4e-03	NA	1.9e-05
6	GTEx	Testis	0.5100	0.0550	0.0e+00	0.592	NA	0.542	NA	0.585	5.3e-32	NA	4.1e-28	NA	2.0e-31
7	GTEx	Thyroid	0.1380	0.0370	3.4e-05	0.077	NA	0.085	NA	0.085	1.6e-06	NA	4.4e-07	NA	4.9e-07
8	METSIM	Adipose	0.1117	0.0238	5.0e-11	0.039	0.080	0.083	0.092	0.085	1.4e-06	5.2e-12	1.9e-12	1.1e-13	9.9e-13
9	ROSMAP	Brain Pre-frontal Cortex	0.2157	0.0325	0.0e+00	0.096	0.169	0.221	0.216	0.224	2.3e-12	3.5e-21	6.5e-28	3.2e-27	2.6e-28
10	TCGA	Kidney Renal Clear Cell Carcinoma	0.0383	0.0215	5.7e-03	0.021	0.007	0.013	NA	0.020	1.8e-03	5.4e-02	1.1e-02	NA	2.1e-03
11	TCGA	Prostate Adenocarcinoma	0.0494	0.0247	9.5e-04	0.022	0.029	0.021	NA	0.026	2.2e-03	4.7e-04	2.7e-03	NA	8.5e-04
12	TCGA	Thyroid Carcinoma	0.1120	0.0480	6.6e-05	0.022	0.042	0.056	NA	0.059	3.0e-03	5.3e-05	3.5e-06	NA	1.9e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Prostate Cancer	10.6	14.9	44.4	-6.7	1.8	1.5	5.3	1.9	-5.8	-5.1	-2.2	-2.5	1.1	-2.3	-4.4
Financial difficulties in last 2 years	3.9	5.2	8.4	1.1	2.8	2.2	-0.0	2.0	2.3	2.6	2.1	2.5	2.5	2.7	2.9
Pain all over the body in last month	3.7	4.0	11.0	0.7	1.9	1.7	0.1	1.7	3.3	2.8	1.9	2.0	1.5	2.4	1.9
Number of operations (self-reported)	3.7	5.5	13.6	1.8	1.9	1.7	0.0	1.6	2.4	2.8	2.8	2.5	2.4	2.5	3.7
Knee pain experienced in last month	3.3	5.1	8.2	-0.6	2.5	2.6	1.5	2.4	1.2	1.5	2.4	2.7	2.9	2.7	2.6
Suffer from ‘nerves’	3.2	5.0	11.9	2.0	1.2	1.1	-1.3	1.2	3.1	3.5	2.4	2.5	0.9	2.9	2.7
Risk taking	2.9	4.2	11.9	2.5	0.8	0.7	-1.4	0.7	2.4	2.7	2.3	2.4	1.2	2.0	3.5
Hearing difficulty/problems with background noise	2.6	4.1	6.8	1.0	2.2	2.0	-0.3	1.9	1.5	2.4	2.6	2.6	1.8	2.1	2.5
Neuroticism score	2.6	5.4	11.6	2.9	1.0	0.7	-1.4	0.6	3.0	3.2	2.6	2.6	0.8	2.7	3.4
Loud music exposure frequency	2.5	2.7	5.3	0.4	-1.4	-1.7	-0.2	-1.6	-1.6	-1.8	-1.9	-1.8	-2.0	-2.3	-1.7
Ever had stillbirth, spontaneous miscarriage or termination	2.5	2.7	5.2	-0.6	2.1	2.3	1.0	2.3	0.5	1.1	1.5	2.0	2.2	1.4	1.2
Hypothyroidism/myxoedema (self-reported)	2.4	4.7	8.0	-0.8	-2.0	-2.3	0.6	-2.2	-1.8	-2.8	-2.7	-2.8	-2.2	-2.2	-2.3
Medication: Atorvastatin	2.4	3.0	8.5	-2.4	0.2	0.1	0.9	0.2	-2.9	-2.2	-1.8	-1.5	0.0	-1.9	-2.6
Type 2 Diabetes (T2D) (2012)	2.3	2.7	6.0	-1.6	2.1	2.4	1.8	2.4	-0.0	0.6	1.2	1.6	2.0	1.0	0.6
Ulcerative Colitis	2.3	3.3	7.0	-0.8	-1.4	-1.5	1.6	-1.7	-2.4	-2.6	-2.0	-2.0	-1.1	-2.2	-1.4
Fed-up feelings	2.3	4.1	11.4	3.4	0.4	0.1	-2.5	-0.0	2.8	2.9	1.8	2.0	-0.1	1.6	2.4
Impedance of leg (left)	2.2	10.6	26.2	-5.1	-0.2	-0.1	2.9	0.1	-4.7	-4.6	-2.5	-3.1	-0.5	-3.4	-4.7
Seen a psychiatrist for nerves, anxiety, tension or depression	2.2	2.9	5.6	0.6	1.3	1.3	-0.5	1.4	2.3	2.4	2.3	1.9	0.9	2.4	1.5
Smoking status: Current	2.2	3.6	7.8	-1.1	2.8	2.4	0.5	2.4	1.0	1.3	1.9	1.5	2.5	2.2	1.4
Lung cancer (father)	2.1	2.5	4.8	-0.2	-2.0	-1.8	-0.3	-1.9	-1.1	-1.8	-1.5	-2.2	-1.5	-1.6	-1.6
Illnesses of mother	2.1	2.7	4.5	-0.1	1.7	1.9	0.7	1.6	0.6	1.4	1.8	2.0	2.1	2.0	2.1
Mood swings	2.1	3.7	7.1	2.0	1.6	1.0	-1.3	1.0	2.3	2.7	2.3	2.3	0.9	2.2	2.5
Tinnitus: Yes, but not now, but have in the past	2.0	2.2	6.6	2.5	-0.6	-0.8	-2.6	-0.8	2.0	2.0	0.2	0.7	-0.6	0.7	1.5
Diverticular disease/diverticulitis (self-reported)	2.0	2.4	4.8	0.2	1.8	1.9	0.1	1.8	1.0	1.2	1.5	1.7	2.2	1.4	1.9
Osteoarthritis (self-reported)	1.9	2.4	8.1	-1.6	1.6	2.1	2.1	1.8	-0.5	0.1	1.1	0.7	2.9	0.7	1.3
Sensitivity / hurt feelings	1.8	3.1	8.2	2.9	-0.3	-0.5	-1.8	-0.6	2.4	2.4	1.7	1.2	-0.2	1.6	2.6
Medication: Metformin	1.8	2.5	5.0	1.8	-2.2	-2.2	-2.0	-2.2	0.8	-0.1	-0.8	-1.3	-2.1	-1.0	-0.7
Headache pain in last month	1.8	3.1	7.1	-0.7	2.7	2.4	1.1	2.2	0.5	1.2	2.0	1.7	2.2	1.7	1.1
Medication: Omeprazole	1.8	2.1	4.5	0.4	2.0	1.7	1.0	2.0	0.9	1.1	1.5	2.1	0.9	1.7	1.1
Chest pain or discomfort	1.8	2.6	5.7	1.7	1.2	1.0	-0.7	1.0	2.1	2.4	1.5	1.8	1.0	1.8	2.1
Medication: Gliclazide	1.8	2.0	5.8	1.8	-2.0	-1.8	-2.4	-1.8	1.2	0.5	-0.4	-1.1	-1.3	-0.5	-0.1
Financial situation satisfaction	1.8	2.2	7.2	0.7	0.8	0.8	-0.5	0.7	2.7	1.7	1.9	1.3	1.0	2.2	1.8
Breast Cancer	1.7	4.0	8.1	2.2	1.2	1.1	-1.4	1.1	2.5	2.8	1.9	2.8	1.0	1.8	2.7
Impedance of leg (right)	1.7	8.0	21.4	-4.6	-0.2	-0.1	2.2	0.0	-3.9	-3.8	-2.1	-2.8	-0.6	-2.8	-4.4
Had other major operations	1.7	2.1	6.5	0.6	1.0	0.8	0.7	0.9	2.5	1.5	1.7	1.3	0.9	2.1	1.8
Happiness	1.7	2.1	4.5	-1.0	1.4	1.9	-0.1	1.9	1.1	1.4	2.1	1.3	1.7	1.6	0.7
Pulse wave peak to peak time	1.7	2.0	9.9	-2.1	1.1	1.5	3.1	1.7	-0.5	-0.4	0.2	0.8	0.9	1.3	-0.4
Medication: Seretide 50 evohaler	1.7	1.9	7.2	2.7	-0.4	-0.7	-2.2	-0.6	1.5	1.9	0.8	0.9	-0.7	0.5	1.3
Miserableness	1.7	2.9	5.9	2.2	0.9	0.4	-1.0	0.7	2.4	2.4	2.0	2.0	-0.1	2.1	1.9
Frequency of depressed mood in last 2 weeks	1.6	2.3	4.5	1.5	1.1	1.1	-0.8	1.1	1.2	2.1	1.9	2.0	0.8	1.6	2.0
Stomach or abdominal pain in last month	1.6	2.0	6.4	-1.5	0.2	0.0	2.3	0.1	-2.5	-2.2	-1.4	-0.8	-0.2	-0.9	-1.1
Worrier / anxious feelings	1.6	3.0	7.4	1.9	0.5	0.5	-1.4	0.1	2.2	2.5	1.9	1.7	1.0	2.0	2.7
Frequency of tiredness / lethargy in last 2 weeks	1.6	2.5	6.6	-1.3	2.6	2.3	1.0	2.4	0.1	1.1	0.9	1.4	1.8	1.5	0.5
Exposure to tobacco smoke at home	1.6	1.8	3.5	0.6	1.4	1.0	-0.1	0.9	1.7	1.8	1.0	1.5	1.1	1.7	1.9
Breastfed as a baby	1.6	2.0	4.8	0.3	1.5	1.3	1.1	1.1	0.9	1.0	1.2	1.9	1.5	1.9	2.2
Qualifications: NVQ or HND or HNC or equivalent	1.6	1.9	7.8	-2.0	1.1	1.2	2.8	1.1	-1.8	-1.6	-0.5	-0.1	1.2	-0.1	-0.4
Illnesses of siblings: Diabetes	1.6	1.9	4.1	-1.1	1.6	2.0	1.3	2.0	-0.1	0.5	1.2	1.6	1.7	1.3	0.8
Impedance of whole body	1.6	8.0	20.3	-4.0	-1.0	-0.8	1.6	-0.7	-3.7	-3.7	-2.4	-3.2	-1.2	-3.1	-4.5
Alzheimer’s Disease (in father)	1.5	1.7	4.2	1.8	-0.6	-0.3	-1.2	-0.6	1.7	1.8	1.4	0.7	0.5	1.1	2.0
Diabetes (father)	1.5	1.9	5.1	1.9	0.2	0.2	-1.9	0.0	1.8	2.3	1.1	1.2	0.3	1.0	1.6
Current tobacco smoking	1.5	2.5	6.1	-0.8	2.5	2.0	0.1	2.0	0.9	1.2	1.6	1.3	2.0	1.8	1.1
Had menopause	1.5	1.9	5.1	-1.3	-0.7	-0.7	1.9	-0.6	-1.2	-2.2	-1.5	-1.0	-1.0	-1.4	-1.7
Heart attack	1.5	1.9	5.4	-1.3	0.2	-0.2	1.1	-0.5	-2.3	-2.0	-1.6	-1.6	0.4	-1.9	-1.1
Asthma	1.5	3.1	7.6	2.2	0.9	0.1	-2.2	0.1	2.8	2.5	1.5	1.4	0.3	2.1	1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	1.5	2.3	5.4	2.2	0.0	-0.0	-1.6	0.0	2.3	2.2	1.4	1.7	-0.0	1.3	1.9
Heart disease (mother)	1.5	1.8	3.9	2.0	-1.9	-1.8	-1.6	-1.9	0.7	0.1	-0.7	-1.0	-1.3	-1.0	0.0
Asthma (self-reported)	1.5	2.9	7.6	2.2	0.7	-0.1	-2.5	-0.1	2.8	2.5	1.3	1.1	0.1	1.9	1.6
Heart attack/myocardial infarction (self-reported)	1.5	1.9	5.0	-1.1	0.0	-0.4	1.1	-0.7	-2.2	-2.0	-1.7	-1.6	0.1	-2.0	-1.1
HDL Cholesterol	1.4	2.3	4.5	-0.2	-1.7	-1.5	0.4	-1.8	-2.1	-2.1	-1.5	-1.4	-0.8	-2.0	-0.8
Hypothyroidism (self reported)	1.4	3.3	5.8	-0.6	-1.6	-2.0	0.1	-2.0	-1.5	-2.2	-2.3	-2.4	-1.9	-1.6	-1.9
Serious illness, injury or assault to yourself	1.4	1.7	4.0	-0.1	1.3	1.4	0.7	1.2	0.4	0.9	1.5	1.2	2.0	1.3	2.0
Length of working week for main job	1.4	1.6	3.7	-0.4	-1.1	-1.1	0.5	-1.0	-1.9	-1.5	-1.6	-1.2	-1.1	-1.6	-1.1
Illnesses of father: High blood pressure	1.4	1.8	5.0	1.2	-1.2	-1.7	-2.2	-1.6	-0.0	0.2	-0.6	-1.3	-1.8	-1.0	-1.3
Depressed Affect (Nagel 2018)	1.3	2.7	5.5	1.0	1.9	1.4	-0.2	1.5	1.6	1.8	1.9	2.3	0.9	2.0	1.8
Worry (Nagel 2018)	1.3	2.8	8.9	1.3	1.0	0.9	-0.1	0.7	1.7	1.9	1.9	1.9	1.4	2.3	3.0
Ovarian Cancer	1.3	1.7	3.9	-1.7	1.8	1.8	1.5	2.0	-0.3	0.3	1.0	1.0	1.5	0.7	0.1
Pack years adult smoking proportion	1.3	2.0	4.6	-0.5	-0.9	-1.3	-0.6	-1.5	-1.5	-1.3	-1.8	-2.0	-0.9	-2.1	-1.4
Medication: Simvastatin	1.3	1.9	4.3	0.5	1.3	1.4	0.3	0.9	1.3	1.6	1.4	1.7	1.7	1.3	2.1
Time employed in main current job	1.3	1.5	2.7	0.1	-1.2	-1.3	-0.6	-1.3	-0.4	-0.9	-1.6	-1.4	-1.6	-1.4	-1.6
Depression (self-reported)	1.3	1.6	3.3	1.8	0.2	0.2	-1.4	0.3	1.4	1.8	0.9	1.7	0.1	1.3	1.8
Pulse wave Arterial Stiffness index	1.3	1.5	8.2	1.7	-0.9	-1.3	-2.9	-1.4	0.2	0.2	-0.1	-0.7	-0.6	-1.3	0.3
Mouth/teeth dental problems: Loose teeth	1.3	1.6	7.5	1.8	-1.3	-1.2	-2.7	-1.3	0.9	1.3	-0.0	-0.3	-0.9	0.1	0.4
Emphysema/chronic bronchitis	1.3	1.5	3.5	0.0	1.9	1.6	0.7	1.7	0.7	0.9	1.2	1.2	1.5	1.2	1.0
Pain experienced in last month	1.3	2.2	4.0	-0.5	-1.4	-1.4	-0.6	-1.2	-1.4	-1.5	-1.6	-1.6	-1.6	-2.0	-2.0
Medication: Co-codamol	1.2	1.4	3.9	-1.5	2.0	1.6	1.8	1.6	-0.7	-0.4	-0.2	0.7	1.2	0.5	-0.1
Average weekly fortified wine intake	1.2	1.4	3.7	-1.5	1.3	1.6	1.6	1.5	-0.4	-0.1	0.3	0.8	1.9	0.7	0.8
Number of incorrect matches in round	1.2	2.0	4.5	-1.9	1.7	1.8	2.1	1.9	0.3	-0.1	1.0	1.2	1.4	1.3	-0.0
Mouth/teeth dental problems: Bleeding gums	1.2	1.6	5.0	1.4	-0.4	-0.2	-2.2	-0.4	1.7	2.1	1.2	0.2	0.5	1.0	1.4
Medication: Ventolin 100micrograms inhaler	1.2	1.6	5.5	2.3	-0.9	-1.5	-1.8	-1.5	1.1	1.0	-0.1	-0.0	-1.0	0.5	1.2
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.5	5.8	-2.2	1.8	2.2	1.2	2.4	-0.2	0.7	1.8	1.0	1.9	1.3	-0.2
Loneliness, isolation	1.2	1.7	3.2	-0.3	1.8	1.8	0.6	1.8	0.4	1.0	1.5	1.4	1.4	1.4	1.0
Guilty feelings	1.2	1.8	5.5	2.3	-0.4	-0.3	-1.3	-0.5	1.5	1.9	1.1	1.2	0.0	0.9	2.1
Medication: Bendroflumethiazide	1.2	1.9	6.4	2.5	-1.1	-1.0	-2.0	-1.1	1.9	1.5	0.8	0.4	-0.6	0.2	1.3
Ever had prostate specific antigen (PSA) test	1.2	1.4	4.6	-2.1	1.0	1.2	1.7	1.2	-1.2	-0.9	-0.2	0.1	1.4	-0.6	-0.6
Age started oral contraceptive pill	1.2	1.5	3.3	-1.1	-1.1	-0.9	0.5	-0.9	-1.1	-1.8	-1.2	-1.5	-0.7	-1.5	-1.5
Deep venous thrombosis (DVT) (self-reported)	1.2	1.5	3.1	0.0	-1.2	-1.5	-0.3	-1.4	-0.7	-1.2	-1.8	-1.7	-1.2	-1.4	-1.2
Pack years of smoking	1.2	1.8	4.5	-0.6	-0.8	-1.2	-0.3	-1.4	-1.3	-1.4	-1.7	-1.9	-0.7	-2.1	-1.3
Ulcerative Colitis (UC)	1.1	2.0	4.5	-0.2	-1.2	-1.3	0.8	-1.3	-1.6	-2.0	-1.4	-1.7	-1.0	-2.1	-1.2
Body Mass Index (BMI) (2010)	1.1	1.5	3.2	-0.5	1.8	1.4	0.1	1.5	1.1	1.3	1.4	1.2	1.0	1.7	0.4
Neuroticism (2016)	1.1	1.6	5.4	2.3	0.2	-0.2	-2.1	-0.1	1.6	1.8	0.7	0.8	-0.1	0.5	1.4
Average weekly spirits intake	1.1	1.3	2.5	-0.3	1.6	1.3	1.2	1.5	0.8	0.3	0.7	1.3	1.2	1.3	1.3
Leg fat-free mass (left)	1.1	5.8	12.0	2.5	1.3	1.3	-1.2	1.2	3.1	3.3	2.6	2.9	1.6	2.8	3.5
Leg predicted mass (left)	1.1	5.7	11.6	2.5	1.3	1.3	-1.2	1.1	3.1	3.2	2.6	2.8	1.5	2.8	3.4
Falls in the last year	1.1	1.4	2.3	0.7	1.5	1.3	0.2	1.3	1.2	1.2	0.9	1.4	1.3	1.2	1.5
Exposure to tobacco smoke outside home	1.1	1.4	3.2	1.8	-1.1	-0.8	-1.2	-1.1	1.8	1.5	1.0	0.4	-0.5	0.9	1.4
Wheeze or whistling in the chest in last year	1.1	2.0	5.0	2.0	0.7	-0.1	-1.7	-0.2	1.8	2.0	0.9	1.0	0.5	1.4	2.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	3.3	-1.3	1.3	1.5	1.8	1.3	-0.5	0.0	1.1	0.6	1.5	0.8	0.1
Eye problems/disorders: Cataract	1.1	1.3	3.2	1.4	-1.7	-1.5	-1.2	-1.8	0.3	-0.3	-0.5	-0.8	-0.9	-1.4	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.3	7.4	-1.4	1.8	1.9	2.7	1.9	-0.6	-0.2	1.1	1.4	1.5	1.2	0.7
Number of self-reported non-cancer illnesses	1.1	1.9	3.8	1.2	1.3	1.0	0.2	1.0	1.7	1.6	1.3	1.9	1.0	1.4	2.0
Ever taken oral contraceptive pill	1.1	1.2	2.0	0.7	1.2	1.0	-0.6	1.1	1.1	1.3	1.3	1.2	0.8	1.4	1.2
Hearing aid user	1.1	1.3	2.8	0.7	-1.2	-1.6	-1.3	-1.6	0.9	-0.1	-1.2	-0.9	-1.7	-0.4	-0.7
Medication: Omeprazole (e.g. Zanprol)	1.1	1.4	3.4	0.0	1.9	1.5	1.2	1.8	0.3	0.6	1.1	1.7	0.5	1.2	0.4
Heart disease (siblings)	1.1	1.3	2.2	0.7	1.0	1.0	1.0	1.0	1.4	1.0	1.4	1.3	0.9	1.5	1.3
Neuroticism (Nagel 2018)	1.0	2.5	6.2	1.8	1.0	0.7	-0.3	0.6	1.8	2.0	1.7	2.0	0.7	1.9	2.5
Lupus	1.0	1.6	4.0	-0.6	-1.1	-1.0	-0.5	-1.2	-2.0	-1.5	-1.6	-1.4	-0.4	-1.8	-0.8
Rheumatoid Arthritis	1.0	1.3	2.8	-0.6	-1.1	-1.2	0.2	-1.1	-0.8	-1.4	-1.7	-1.6	-1.1	-1.2	-1.1
Vitamin and mineral supplements	1.0	1.4	4.7	-0.7	1.4	1.6	0.7	1.4	0.0	0.5	1.2	0.8	2.2	0.8	1.2
Medication: Levothyroxine sodium	1.0	1.6	3.4	-0.3	-1.1	-1.4	0.5	-1.4	-0.9	-1.7	-1.8	-1.3	-1.5	-1.3	-1.3
Allergy	1.0	2.3	5.7	-2.4	-0.6	-0.1	2.0	-0.0	-1.8	-2.2	-1.3	-1.3	-0.4	-1.6	-2.0
Illnesses of siblings	1.0	1.4	3.5	-0.5	-1.1	-0.9	-0.8	-0.9	-1.2	-1.1	-1.8	-1.3	-0.6	-1.9	-1.2
Medication: Allopurinol	1.0	1.3	5.2	-1.5	-0.3	-0.1	1.2	-0.3	-2.3	-1.7	-0.7	-0.9	-0.1	-1.2	-1.1
Had major operations	1.0	1.2	4.0	1.5	0.4	0.4	-1.3	0.2	0.9	1.5	1.1	0.6	1.2	0.7	2.0
Leg predicted mass (right)	1.0	5.3	12.2	2.5	1.1	1.2	-1.1	1.0	2.8	3.0	2.5	2.7	1.5	2.6	3.5
Relative age of first facial hair	0.9	1.8	5.1	-1.3	-1.4	-0.8	0.2	-1.1	-2.3	-1.8	-0.9	-1.7	-0.4	-1.7	-1.2
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	2.4	0.4	-1.3	-1.4	0.0	-1.6	-1.3	-1.1	-1.4	-1.0	-0.7	-1.3	0.1
Waist circumference	0.9	3.2	6.1	0.5	2.5	1.9	0.5	1.7	1.5	1.6	1.6	2.4	1.9	1.6	2.3
Father’s age at death	0.9	1.3	3.1	1.0	-1.7	-1.6	-1.2	-1.8	-0.3	-0.5	-0.5	-0.8	-1.5	-0.7	-0.3
Impedance of arm (left)	0.9	4.2	11.6	-2.2	-1.4	-1.3	0.1	-1.3	-2.0	-2.3	-2.0	-2.7	-1.7	-2.4	-3.4
Tense / ‘highly strung’	0.9	1.4	3.2	0.9	1.0	0.9	0.1	0.8	1.1	1.2	1.8	1.4	0.8	1.6	1.7
Blood clot in the leg (DVT)	0.9	1.2	2.7	0.0	-0.9	-1.3	-0.4	-1.2	-0.5	-1.0	-1.6	-1.5	-1.1	-1.2	-1.1
Medication: Paracetamol	0.9	1.5	3.2	-0.6	-0.9	-0.9	0.6	-1.2	-1.6	-1.5	-1.8	-1.7	-0.6	-1.5	-1.0
Worry too long after embarrassment	0.9	1.5	4.1	1.7	0.0	-0.0	-1.5	-0.1	2.0	2.0	0.8	0.8	0.2	1.3	1.5
Whole body fat-free mass	0.9	5.0	11.1	1.9	1.3	1.6	-0.6	1.5	2.4	2.7	2.7	2.7	1.9	2.6	3.3
Leg fat-free mass (right)	0.9	5.1	11.6	2.5	1.1	1.2	-1.1	1.0	2.8	3.0	2.5	2.7	1.5	2.5	3.4
Handedness (chirality/laterality): Left-handed	0.9	1.1	2.3	0.9	-1.0	-1.5	-1.0	-1.5	-0.2	-0.5	-1.4	-0.7	-1.3	-1.1	-0.3
Whole body water mass	0.9	5.1	11.3	1.9	1.3	1.6	-0.6	1.5	2.5	2.8	2.7	2.8	1.9	2.6	3.4
Eye problems/disorders: Glaucoma	0.9	1.0	3.1	1.8	-0.3	-0.3	-1.2	-0.4	1.6	1.5	0.7	0.7	-0.1	0.2	1.1
Irritable Bowel Disease (IBD)	0.8	1.8	4.1	-0.0	-1.1	-1.4	0.3	-1.5	-1.2	-1.6	-1.6	-1.8	-1.0	-2.0	-1.2
Respiratory disease	0.8	1.9	6.0	1.8	0.6	-0.2	-2.0	-0.0	2.4	1.9	0.9	1.0	-0.5	1.6	0.8
Neuroticism	0.8	2.0	4.1	1.6	1.1	0.6	-0.8	0.6	1.6	1.9	1.4	1.7	0.6	1.8	2.0
Hand grip strength (left)	0.8	2.0	6.3	-1.6	-0.8	-0.4	0.9	-0.3	-2.5	-1.9	-1.0	-1.3	-0.5	-1.7	-2.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	2.4	-1.3	1.4	1.5	1.3	1.5	-1.2	-0.3	0.6	0.6	0.9	0.0	-0.4
Body mass index (BMI)	0.8	3.6	8.5	2.4	1.8	1.0	-0.6	0.8	2.5	2.2	1.4	2.6	1.0	1.9	2.9
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	2.9	0.9	0.5	0.8	-0.7	0.6	0.6	1.7	1.4	1.4	1.0	1.1	1.6
Trunk predicted mass	0.8	4.4	9.9	1.5	1.3	1.7	-0.3	1.6	2.1	2.4	2.7	2.6	2.1	2.4	3.1
Ever highly irritable/argumentative for 2 days	0.8	0.9	2.3	0.8	-1.0	-1.4	-1.0	-1.3	-0.0	-0.3	-0.7	-1.0	-1.5	-0.9	-0.8
Gout (self-reported)	0.8	1.0	2.7	-1.1	-0.6	-0.7	0.3	-0.7	-1.5	-1.2	-0.8	-1.0	-1.0	-0.9	-1.6
Qualifications: nursing, teaching	0.8	1.3	3.3	1.1	-1.7	-1.6	-1.8	-1.6	0.7	0.1	-0.1	-0.7	-1.0	-0.8	0.0
Basal metabolic rate	0.8	4.4	9.6	1.7	1.5	1.6	-0.4	1.4	2.2	2.5	2.5	2.6	1.9	2.4	3.1
Arm fat-free mass (left)	0.8	3.8	8.1	1.0	1.6	1.8	0.3	1.7	1.6	2.0	2.4	2.6	2.1	2.2	2.9
Average weekly beer plus cider intake	0.8	1.2	4.5	-2.1	1.0	0.9	1.4	0.8	-1.7	-1.0	-0.4	-0.3	0.8	-0.3	-0.9
Ever depressed for a whole week	0.8	1.0	2.1	0.5	-1.3	-1.4	-0.2	-1.4	-0.7	-0.9	-0.5	-1.2	-1.0	-1.2	-0.6
Arm predicted mass (left)	0.8	3.8	8.6	1.2	1.5	1.7	0.1	1.6	1.8	2.0	2.3	2.6	1.9	2.2	2.9
Schizophrenia vs Biploar Disorder	0.7	0.9	2.4	-1.5	-0.5	-0.2	1.0	-0.1	-1.1	-1.3	-1.0	-1.3	0.2	-0.7	-0.9
BMI	0.7	3.8	7.8	2.1	1.8	1.0	-0.8	0.8	2.6	2.4	1.6	2.5	0.9	2.3	2.8
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	1.9	0.1	-0.3	-0.5	-0.1	-0.3	-1.0	-0.8	-1.2	-0.6	-1.1	-1.4	-1.2
Supplements: Zinc	0.7	0.7	1.5	0.1	-1.1	-1.0	-1.2	-0.9	-1.0	-0.6	-0.1	-0.6	-1.0	-0.9	-0.6
Hand grip strength (right)	0.7	1.9	5.9	-2.2	-0.2	0.1	1.2	0.2	-2.4	-2.0	-0.8	-1.0	-0.2	-1.1	-2.0
Taking other prescription medications	0.7	1.1	2.3	0.8	-0.9	-1.4	0.2	-1.4	-0.7	-1.2	-1.5	-1.0	-1.5	-0.8	-0.4
Nervous feelings	0.7	1.2	3.4	0.3	0.5	0.8	0.8	0.8	0.8	1.3	1.4	1.1	1.0	1.6	1.8
Hair/balding pattern: Pattern 2	0.7	0.9	2.1	0.3	0.8	0.7	-0.0	1.1	1.1	1.3	1.3	1.2	-0.2	1.5	0.4
Trunk fat-free mass	0.7	4.1	9.2	1.4	1.2	1.6	-0.3	1.6	2.0	2.3	2.5	2.5	2.0	2.3	3.0
Hair/balding pattern: Pattern 3	0.7	1.0	1.8	-0.5	-1.3	-1.0	0.1	-1.1	-0.6	-1.4	-1.1	-1.3	-0.7	-1.3	-1.1
Medication: Lansoprazole	0.7	0.8	2.0	-0.3	-0.7	-0.5	-0.0	-0.4	-0.9	-1.2	-1.4	-0.8	-0.8	-1.4	-1.1
Pulse wave reflection index	0.7	0.9	2.1	0.8	-0.9	-1.0	-1.3	-1.3	-0.1	-0.6	-0.8	-1.1	-0.3	-1.4	0.0
Medication: Amlodipine	0.7	0.9	2.8	-1.7	0.4	0.3	1.3	0.4	-1.3	-1.4	-0.8	-0.6	-0.1	-0.3	-1.2
Number of children fathered	0.7	0.8	1.9	-0.0	0.8	0.9	0.2	0.8	0.7	0.6	1.2	1.2	1.1	0.9	1.4
Health satisfaction	0.7	0.9	2.6	-0.5	1.6	1.3	0.3	1.3	0.3	0.8	0.8	1.1	1.0	0.6	0.3
Neck or shoulder pain in last month	0.7	1.0	3.6	1.4	0.5	0.6	0.4	0.4	0.6	0.8	1.1	1.3	0.7	1.3	1.9
Arm predicted mass (right)	0.7	3.4	6.2	0.8	1.6	1.8	0.3	1.8	1.5	1.8	2.3	2.3	2.0	2.1	2.5
Age at last live birth	0.7	1.0	2.3	-1.2	0.9	1.4	0.8	1.5	0.3	0.5	1.4	0.8	1.2	1.0	-0.0
Medication: Aspirin	0.7	0.9	1.6	-0.0	1.2	1.0	0.9	0.8	0.2	0.5	1.2	1.2	1.2	0.9	1.2
Medication: Blood pressure	0.7	1.4	2.9	-0.5	-0.7	-0.7	1.3	-0.5	-0.7	-1.7	-1.7	-1.2	-1.0	-1.4	-1.6
Medication: Lisinopril	0.7	0.8	2.2	-0.3	-0.4	-0.8	0.3	-0.8	-0.6	-1.4	-1.5	-0.8	-1.1	-0.8	-1.1
Bipolar Disorder (2018)	0.6	0.9	1.8	1.4	0.7	0.4	-0.7	0.5	1.3	1.0	1.0	1.3	0.2	0.8	1.1
LDL Cholesterol	0.6	1.0	3.2	-1.2	-0.2	-0.3	1.2	-0.0	-1.0	-1.1	-0.9	-1.0	-1.1	-0.3	-1.8
Alcohol usually taken with meals	0.6	1.0	3.6	1.1	-1.9	-1.2	-1.7	-1.2	-0.1	0.1	0.1	-0.3	-1.0	-0.8	0.1
Diabetes (self-reported)	0.6	0.9	2.4	1.5	-1.2	-1.3	-1.0	-1.2	0.8	-0.2	-0.4	-0.5	-1.4	-0.3	-0.2
Impedance of arm (right)	0.6	3.0	7.5	-1.8	-1.3	-1.2	-0.1	-1.2	-1.6	-1.8	-1.7	-2.2	-1.4	-2.1	-2.7
Hip circumference	0.6	2.7	5.8	1.2	1.8	1.4	0.3	1.2	1.6	1.6	1.7	2.4	1.4	1.7	2.4
Alcohol intake versus 10 years previously	0.6	0.9	1.5	0.7	1.1	0.7	-0.8	0.7	1.2	1.2	1.1	1.1	0.8	0.6	1.1
Number of live births	0.6	0.8	1.6	-0.3	0.9	1.0	0.9	0.8	0.8	0.8	0.5	1.0	1.3	0.9	1.3
Noisy workplace	0.6	0.8	1.7	-0.3	1.3	1.3	0.5	1.2	0.3	0.5	0.8	1.0	1.1	0.7	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	2.4	1.2	0.3	0.1	-1.5	-0.2	1.0	1.6	0.1	0.3	0.6	0.7	1.2
Hair/balding pattern: Pattern 4	0.6	1.4	3.0	-1.4	1.2	1.4	1.7	1.5	-1.4	-0.7	-0.2	0.5	1.7	-0.1	0.0
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.5	-1.3	1.6	1.1	0.3	1.3	-0.5	0.1	0.1	0.1	0.7	0.0	-0.8
Arm fat-free mass (right)	0.6	3.0	6.2	0.9	1.5	1.6	0.3	1.6	1.4	1.8	2.1	2.2	1.9	2.1	2.5
Qualifications: College or University degree	0.6	1.9	6.4	1.2	-2.5	-1.8	-1.9	-2.0	0.2	-0.1	-0.2	-1.2	-0.9	-1.2	0.2
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	2.2	0.6	-1.5	-1.2	-0.6	-1.2	0.3	-0.2	-0.3	-0.5	-1.3	-0.3	-0.5
Average weekly red wine intake	0.6	0.8	2.6	1.5	-0.5	0.1	-0.8	-0.1	0.8	0.9	1.2	0.9	0.7	0.5	1.6
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	3.0	0.5	-1.2	-1.4	-0.3	-1.2	-0.6	-0.5	-0.6	-0.9	-1.7	-0.7	-1.0
Commuting to job workplace: Public transport	0.6	0.8	2.4	0.6	-1.5	-1.2	-0.9	-1.3	0.4	0.3	-0.3	-1.1	-0.9	0.0	-0.3
High cholesterol (Self-reported)	0.6	1.1	2.9	-0.2	1.3	1.4	0.6	1.2	0.1	0.7	0.7	1.4	1.7	0.7	1.2
Major Depression (MDD)	0.5	0.6	2.5	0.8	-0.5	-0.5	-0.9	-0.2	1.6	1.1	0.1	0.4	-0.9	0.7	-0.1
Fasting Glucose	0.5	0.5	2.5	-1.6	0.5	0.9	0.8	1.0	-0.2	-0.2	-0.5	-0.0	0.9	0.1	-0.4
Relative age voice broke	0.5	0.7	3.0	0.6	-0.8	0.1	-1.1	-0.3	0.3	1.2	1.7	0.5	0.4	0.5	1.1
Age when periods started (menarche)	0.5	1.3	5.1	1.8	-0.9	-1.1	-2.3	-1.4	0.7	1.1	-0.1	-0.4	-0.7	0.1	0.8
Weight	0.5	2.7	6.3	1.2	1.6	1.4	-0.1	1.2	1.7	1.8	1.6	2.2	1.6	1.6	2.5
High blood pressure (siblings)	0.5	0.7	2.8	1.7	-0.2	-0.2	0.3	-0.2	0.8	0.6	1.4	0.9	-0.5	0.8	1.0
Eye problems/disorders: None of the above	0.5	0.6	1.5	-0.9	0.9	0.8	0.9	1.1	-0.3	0.2	0.5	0.6	0.1	1.2	-0.4
Medication: Blood pressure	0.5	0.8	2.7	1.6	-1.0	-1.1	-1.1	-1.2	1.0	0.4	-0.0	0.2	-0.8	0.0	0.8
Medication: Ibuprofen	0.5	0.6	2.9	1.0	-0.4	-0.6	-1.7	-0.8	0.5	0.8	-0.6	-0.5	0.1	-0.1	0.5
Family relationship satisfaction	0.5	0.6	2.4	-1.6	0.7	0.6	0.2	0.6	-0.6	-1.0	0.2	-0.5	0.5	-0.6	-0.9
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.7	1.0	0.6	0.2	-1.1	0.2	0.8	1.0	0.6	0.9	0.4	0.3	1.3
Osteoporosis (self-reported)	0.5	0.7	2.6	-1.6	0.3	0.5	0.8	0.3	-1.1	-0.7	-0.0	-1.1	1.0	-0.6	-0.4
Fractured/broken bones in last 5 years	0.5	0.6	1.2	0.8	-1.1	-1.1	-0.8	-1.1	-0.4	-0.5	-0.6	-0.6	-0.6	-0.9	0.2
Schizophrenia (2018)	0.4	0.9	2.5	-1.6	0.4	0.1	1.6	0.4	-0.8	-1.0	-0.5	-0.4	-0.5	-0.6	-1.6
Diabetes (mother)	0.4	0.5	1.4	-1.1	0.5	0.3	0.9	0.5	-0.9	-0.7	-0.7	-0.6	-0.2	-0.6	-1.2
High blood pressure (mother)	0.4	0.5	2.2	0.0	-0.7	-0.8	0.1	-0.5	-0.1	-0.8	-0.3	-0.5	-1.5	-0.4	-1.3
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.3	0.4	1.1	0.8	0.3	0.8	-0.2	0.6	0.8	0.9	0.9	0.6	0.9
Medication: Cholesterol lowering	0.4	0.6	2.1	1.5	-0.4	-0.9	-0.5	-1.1	-0.4	-0.1	-0.6	0.0	-0.6	-0.9	0.5
Arm fat mass (right)	0.4	1.6	4.0	1.6	1.3	0.7	-0.4	0.5	1.7	1.4	0.9	1.7	0.7	1.1	2.0
Glaucoma (self-reported)	0.4	0.4	1.8	1.3	-0.4	-0.4	-0.8	-0.4	0.9	0.8	0.4	0.4	-0.3	-0.2	0.8
Number of full brothers	0.4	0.5	1.9	0.6	0.5	0.4	-0.1	0.4	0.7	1.0	1.4	0.3	0.6	0.9	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	2.6	-0.8	0.5	0.7	1.6	0.6	-0.3	-0.3	0.1	0.5	0.8	0.3	0.5
Age at first live birth	0.4	0.8	2.1	-0.6	-1.1	-0.7	-0.1	-0.5	-1.1	-1.0	-0.3	-1.0	-0.8	-0.9	-1.5
Shortness of breath walking on level ground	0.4	0.5	1.5	0.8	0.5	-0.4	-1.2	-0.3	0.8	0.8	-0.4	0.3	-1.2	0.0	-0.5
Overall health rating	0.4	0.8	1.5	1.0	1.2	0.7	-0.4	0.7	1.0	1.2	0.8	0.9	0.5	0.7	1.1
Medication: Aspirin	0.4	0.5	1.3	0.3	0.8	0.6	1.0	0.3	-0.0	0.2	0.8	0.8	0.9	0.4	1.2
Supplements: Vitamin C	0.4	0.5	1.9	1.1	-0.7	-1.0	0.1	-0.8	0.4	0.0	-0.3	0.1	-1.4	0.1	0.0
Smoking status: Previous	0.4	0.6	1.8	1.3	-0.9	-1.0	-0.9	-1.2	-0.2	-0.0	0.1	-0.4	-0.4	-0.5	0.7
Ever had bowel cancer screening	0.4	0.5	1.0	0.2	-0.9	-0.9	0.2	-1.0	-0.3	-1.0	-0.2	-0.7	-1.0	-0.7	-0.6
Diabetes diagnosed by doctor	0.4	0.6	1.5	1.1	-0.9	-1.0	-0.8	-0.9	0.6	-0.2	-0.5	-0.6	-1.2	-0.3	-0.5
Back pain experienced in last month	0.4	0.6	1.5	-0.7	1.1	0.9	1.2	0.9	-0.9	-0.6	0.2	0.7	0.8	-0.1	0.2
Illnesses of father: None of the above (group 1)	0.4	0.5	1.1	-0.6	-1.0	-0.4	0.1	-0.4	-0.6	-1.0	-0.8	-0.8	-0.7	-0.7	-1.1
Mother’s age at death	0.4	0.5	2.1	-1.5	0.1	0.1	0.5	0.1	-0.8	-1.1	-0.1	-0.7	0.5	-0.4	-0.8
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.6	0.2	-0.5	-0.3	0.8	-0.4	-1.2	-1.3	-0.1	-0.2	-0.3	-1.1	-0.3
Irritability	0.4	0.6	3.1	1.6	-0.0	-0.3	-0.4	-0.7	0.6	0.5	0.2	0.5	0.2	0.3	1.8
Cholesterol lowering medication	0.4	0.7	2.3	-0.6	0.7	1.0	1.0	0.7	0.4	0.4	0.6	0.6	1.5	0.6	0.9
Leg fat mass (left)	0.4	1.4	4.0	0.4	2.0	1.3	0.5	1.1	0.9	0.8	0.6	1.6	1.3	0.9	1.5
Depression (Nagel 2018)	0.3	0.5	1.2	-0.2	0.8	0.8	0.4	0.9	0.1	0.8	1.0	1.1	0.4	0.9	0.5
Reaction Time	0.3	0.5	2.4	-0.8	-0.1	-0.2	0.8	0.1	0.3	-0.3	-0.9	-0.7	-0.9	0.2	-1.5
Bipolar Disorder (2011)	0.3	0.3	2.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.0	1.5	0.4
Mean Putamen Volume	0.3	0.4	1.1	-1.0	0.2	0.4	0.7	0.3	-0.5	-0.9	-0.7	-0.3	0.7	-0.2	-0.6
Systolic Blood Pressure	0.3	1.4	3.6	0.1	-1.5	-1.4	-0.0	-1.2	-0.8	-1.0	-0.8	-0.8	-1.9	-1.5	-1.7
Smoking Status	0.3	0.8	2.6	-0.6	1.6	1.1	0.4	0.9	0.0	0.4	0.8	0.4	1.3	1.0	0.5
Allergy or Eczema	0.3	0.8	1.9	0.7	-0.9	-1.2	-0.8	-1.4	-0.3	-0.5	-1.0	-0.9	-1.1	-0.8	-0.5
Lung FEV1/FVC ratio	0.3	1.7	4.7	-2.2	1.2	1.6	2.0	1.4	-1.5	-0.7	-0.2	0.2	1.8	-0.0	-0.2
Number of treatments/medications taken	0.3	0.5	2.0	1.4	0.4	-0.2	0.0	-0.3	0.8	0.4	-0.0	0.9	-0.1	0.6	1.4
Systolic blood pressure, automated reading	0.3	0.8	1.9	0.7	-1.4	-1.2	0.1	-1.2	-0.6	-0.9	-0.6	-0.6	-1.1	-1.2	-0.6
Medication for hormone replacement therapy	0.3	0.4	1.1	1.1	-0.1	-0.0	-0.8	0.0	0.7	0.7	0.7	0.5	-0.4	0.7	0.3
Severe depression (siblings)	0.3	0.4	0.9	-1.0	0.8	0.7	-0.1	0.8	0.0	-0.0	0.7	0.2	0.0	0.6	-0.9
Maternal smoking around birth	0.3	0.4	1.1	0.7	0.7	0.4	-0.8	0.6	0.6	1.0	0.5	0.6	0.0	0.3	0.0
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	1.2	-0.6	1.0	1.0	1.1	1.1	0.2	0.1	0.5	0.8	1.0	0.4	0.4
Multivitamins +/- minerals	0.3	0.3	0.8	0.0	-0.5	-0.6	-0.2	-0.4	-0.4	-0.5	-0.8	-0.5	-0.9	-0.8	-0.8
Chronic bronchitis/emphysema (father)	0.3	0.3	0.8	-0.4	0.1	-0.5	0.1	-0.6	-0.8	-0.9	-0.6	-0.7	-0.5	-0.5	-0.6
Mouth/teeth dental problems	0.3	0.5	1.4	-0.1	-0.5	-0.5	0.7	-0.5	-0.9	-1.2	-0.8	-0.4	-0.7	-0.9	-0.5
Arm fat percentage (right)	0.3	1.3	3.1	1.8	1.1	0.3	-0.7	0.0	1.7	1.3	0.3	1.5	0.3	0.7	1.8
Prospective memory result	0.3	0.4	1.1	1.0	-0.4	-0.7	-1.1	-0.5	0.1	0.2	-0.2	-0.3	-1.0	-0.6	-0.5
Migraine (self-reported)	0.3	0.4	1.5	-0.4	0.8	0.7	0.7	0.7	-1.2	-0.5	0.7	0.2	0.7	-0.2	0.2
Leg fat mass (right)	0.3	1.2	3.2	0.6	1.8	1.1	0.2	0.8	1.1	0.9	0.5	1.6	1.0	1.0	1.5
Comparative height size at age 10	0.3	1.8	5.7	-2.4	0.8	1.1	1.6	1.3	-1.9	-1.6	0.1	-0.2	0.8	-0.8	-1.6
Number of full sisters	0.3	0.4	1.0	-1.0	0.9	0.2	0.8	-0.0	-0.9	-0.7	-0.9	-0.4	0.3	-0.2	-0.4
Leg pain on walking	0.3	0.4	1.5	-0.3	-0.2	-0.5	-0.0	-0.3	-0.4	-0.5	-0.5	-0.8	-1.1	-0.3	-1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	0.9	0.9	-0.2	-0.7	0.4	-0.7	-0.1	-0.6	-1.0	-0.3	-0.8	-0.7	-0.3
Illnesses of father: Heart disease	0.3	0.5	2.3	-0.8	0.7	0.6	1.5	0.6	-0.6	-0.8	-0.3	0.2	0.7	-0.1	0.1
Arm fat percentage (left)	0.3	1.0	2.8	1.7	1.0	0.2	-0.7	-0.1	1.6	1.2	0.2	1.3	0.1	0.6	1.5
Long-standing illness, disability or infirmity	0.3	0.5	1.3	1.1	-0.4	-0.8	-0.2	-0.7	0.0	-0.4	-0.9	-0.6	-0.8	-1.0	0.2
Arm fat mass (left)	0.3	1.4	3.3	1.4	1.3	0.7	-0.4	0.5	1.6	1.4	0.8	1.6	0.7	1.1	1.8
Average weekly champagne plus white wine intake	0.3	0.4	1.4	-0.6	0.5	0.7	0.4	0.9	0.4	0.5	1.2	0.8	-0.1	0.8	-0.3
Medication: Paracetamol	0.3	0.5	1.0	0.0	-0.5	-0.6	0.0	-0.8	-0.8	-0.8	-1.0	-1.0	-0.4	-1.0	-0.4
Ever smoked	0.3	0.5	1.5	1.1	0.4	0.0	-0.8	-0.2	0.4	0.7	0.9	0.4	0.6	0.2	1.2
Leg fat percentage (left)	0.3	0.9	4.0	-0.5	2.0	1.2	1.4	1.0	-0.1	-0.4	-0.2	1.0	1.1	0.1	0.7
Commuting to job workplace: Cycle	0.3	0.4	1.0	-0.6	-0.7	-0.5	-0.2	-0.7	-1.0	-0.9	-0.4	-0.6	-0.1	-0.2	-0.2
Myopia	0.3	0.5	1.3	1.1	-0.9	-0.8	-1.0	-0.7	0.7	0.6	0.1	0.0	-1.0	0.1	0.1
Alzheimer’s Disease (in mother)	0.2	0.3	0.5	-0.0	0.6	0.5	-0.5	0.5	-0.4	0.7	0.7	0.6	0.6	-0.0	0.5
Alzheimer’s Disease (including proxy)	0.2	0.3	1.2	0.5	-0.2	-0.1	-0.4	-0.3	0.3	0.8	0.5	0.5	0.5	0.1	1.1
Coronary Artery Disease (CAD)	0.2	0.2	1.1	-0.4	0.2	0.0	-0.1	0.3	0.5	0.5	-0.2	-0.3	-0.4	0.4	-1.0
Crohns Disease (2012)	0.2	0.2	0.6	-0.3	-0.6	-0.5	0.7	-0.5	-0.2	-0.6	-0.7	-0.3	-0.5	-0.2	-0.5
HbA1C	0.2	0.2	1.0	-0.5	0.6	0.3	1.0	0.3	0.1	-0.2	-0.2	0.5	0.4	0.4	0.2
Blood White Count	0.2	1.5	3.2	-1.0	1.8	1.7	1.1	1.4	1.0	0.8	1.0	1.3	1.4	1.3	0.4
Height	0.2	4.7	12.7	-3.5	1.4	2.3	3.6	2.4	-2.6	-1.7	0.8	0.2	2.9	-0.4	0.1
Tanning	0.2	2.5	5.8	1.4	1.4	1.1	0.2	1.1	1.8	2.2	1.4	1.6	1.2	2.0	2.4
Hearing difficulty/problems: Yes	0.2	0.4	1.6	1.3	-0.4	-0.3	-0.9	-0.5	0.3	0.3	0.2	0.4	-0.3	0.2	0.9
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.7	0.8	-0.4	-0.3	0.4	-0.2	0.0	-0.2	0.2	0.7	-0.6	0.6	0.6
Townsend deprivation index at recruitment	0.2	0.3	1.1	0.5	-0.1	-0.5	-1.1	-0.5	-0.1	0.2	-0.3	-0.5	-0.9	-0.4	-0.7
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.0	1.0	-0.7	-0.9	-1.0	-1.0	-0.0	0.1	-0.4	-0.5	-0.7	-0.2	0.1
Supplements: Glucosamine	0.2	0.3	1.0	-1.0	0.4	0.5	0.9	0.6	-0.5	-0.7	-0.2	-0.1	0.4	0.0	-0.5
Sitting height	0.2	1.1	3.0	-1.7	0.1	1.1	1.0	1.1	-1.7	-0.8	0.7	-0.3	1.5	-0.8	-0.5
Trunk fat mass	0.2	0.6	2.4	0.0	1.6	1.0	0.5	0.8	0.5	0.3	0.4	1.1	0.9	0.5	0.9
Past tobacco smoking	0.2	0.3	1.2	-0.7	-0.2	0.0	0.6	0.3	-0.1	-0.4	-0.7	-0.1	-0.6	-0.0	-1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.0	-0.9	0.3	0.6	1.0	0.5	-0.7	-0.8	-0.5	-0.2	0.9	-0.4	-0.1
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.6	-0.1	-0.3	-0.4	-0.6	-0.3	-0.3	-0.1	0.4	-0.6	-0.5	-0.6	-0.8
Pulse rate	0.2	0.4	0.9	-0.1	0.8	0.8	-0.2	1.0	0.4	0.5	0.9	0.8	0.5	0.6	0.3
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.2	0.7	-0.7	-0.1	-1.1	-0.3	0.2	1.0	1.1	0.5	0.5	0.2	1.1
Mouth/teeth dental problems: Dentures	0.2	0.3	1.0	-0.4	1.0	0.6	0.6	0.7	-0.2	-0.2	-0.5	0.5	0.3	-0.0	-0.2
Birth weight of first child	0.2	0.3	1.3	-0.2	0.5	0.5	-0.2	0.3	0.8	0.5	0.4	0.3	1.1	0.2	0.8
Peak expiratory flow (PEF)	0.2	0.4	1.3	-1.2	0.2	0.7	0.9	0.8	-0.6	-0.2	-0.2	0.2	0.4	-0.1	-0.7
Leg fat percentage (right)	0.2	0.8	3.6	-0.3	1.9	1.0	1.1	0.8	0.2	-0.1	-0.3	1.0	0.9	0.2	0.6
Mean time to correctly identify matches	0.2	0.4	2.0	-0.7	-0.3	-0.2	1.4	0.0	0.5	-0.4	-0.7	-0.4	-0.8	0.2	-1.0
Whole body fat mass	0.2	1.0	2.9	0.5	1.7	1.1	0.4	0.8	0.9	0.6	0.5	1.4	1.0	0.8	1.4
Alcohol intake frequency.	0.2	0.6	1.4	0.4	1.2	0.8	0.1	0.9	0.7	0.7	0.5	1.2	0.4	0.7	0.7
Friendships satisfaction	0.2	0.2	0.8	-0.9	0.3	0.5	-0.4	0.3	-0.2	-0.0	0.5	-0.4	0.7	-0.3	-0.2
Commuting to job workplace: Walk	0.2	0.2	0.9	0.2	-0.1	0.3	0.7	0.2	-0.9	-0.4	0.1	0.5	0.1	-0.2	0.4
Medication for cholesterol	0.2	0.3	0.9	0.1	-0.0	0.1	-0.8	0.1	0.5	1.0	0.9	0.2	0.2	0.5	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.3	1.3	0.4	-0.2	-0.4	-0.6	-0.2	0.2	0.1	-0.1	-0.2	-1.1	-0.2	-0.9
Mineral and other dietary supplements	0.2	0.3	1.9	0.5	-0.1	-0.5	-1.4	-0.6	0.6	0.5	-0.2	-0.5	-0.4	-0.3	-0.2
Wears glasses or contact lenses	0.2	0.2	0.6	-0.2	-0.4	-0.5	-0.1	-0.4	0.1	-0.7	-0.5	-0.6	-0.5	-0.6	-0.6
Alcohol drinker status: Never	0.2	0.2	0.7	0.7	-0.1	-0.5	-0.3	-0.3	0.6	0.4	0.4	0.2	-0.6	0.8	0.3
Diastolic blood pressure, automated reading	0.2	0.7	2.2	1.5	0.4	0.3	-0.8	0.2	0.9	1.1	0.8	1.2	0.5	0.3	1.3
Basal cell carcinoma (self-reported)	0.2	0.3	1.1	-0.0	-0.6	-0.5	1.1	-0.4	0.1	-0.8	-0.4	-0.2	-0.5	-0.0	-0.1
Bipolar Disorder or Schizophrenia	0.1	0.2	0.6	-0.4	0.8	0.4	0.7	0.6	0.2	-0.0	0.3	0.7	-0.3	0.0	-0.6
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.8	-0.6	-0.1	0.2	0.1	0.0	-0.5	-0.3	-0.1	-0.4	0.1	-0.9	-0.5
Crohns Disease (2017)	0.1	0.3	0.9	0.6	-0.5	-0.8	-0.4	-0.9	0.2	-0.1	-0.6	-0.5	-0.6	-0.6	-0.3
Age at First Birth	0.1	0.2	0.6	0.3	-0.8	-0.5	-0.5	-0.4	0.8	-0.0	-0.1	-0.6	0.1	-0.2	0.3
Primary Biliary Cirrhosis	0.1	0.1	0.5	0.1	-0.1	-0.3	0.5	-0.3	-0.3	-0.6	-0.7	-0.1	-0.3	-0.3	0.1
Schizophrenia (2014)	0.1	0.2	0.8	-0.4	0.2	-0.1	0.4	0.1	0.2	-0.2	-0.0	0.1	-0.9	0.0	-0.9
Triglycerides	0.1	0.2	1.0	-0.1	1.0	0.5	0.1	0.7	0.4	0.5	0.2	0.1	0.0	0.8	0.1
Blood Eosinophil Count	0.1	0.9	4.5	1.1	0.4	-0.2	-0.8	-0.2	2.1	1.3	0.8	0.7	-0.7	0.8	0.2
Blood Red Count	0.1	1.0	2.6	1.6	-0.4	-0.1	-1.2	0.0	1.4	1.1	0.9	1.1	0.0	0.8	1.3
Waist Hip Ratio (WHR)	0.1	0.6	2.0	-1.4	0.4	0.2	0.3	0.3	-1.0	-0.5	-0.8	-0.6	0.1	-1.0	-1.0
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.4	0.5	-0.4	-0.5	-0.5	-0.5	-0.1	-0.3	-0.5	-0.4	-0.7	-0.2	-0.4
Hair Pigment	0.1	3.3	13.6	-1.0	1.7	2.0	-0.0	1.6	0.6	1.1	1.4	1.2	3.7	1.7	2.8
Ever had hysterectomy (womb removed)	0.1	0.1	0.3	0.1	0.1	-0.2	-0.5	-0.1	-0.3	-0.2	-0.1	-0.3	-0.4	-0.5	-0.3
Trunk fat percentage	0.1	0.3	1.7	-0.4	1.3	0.5	0.7	0.3	0.0	-0.5	-0.3	0.4	0.4	-0.1	0.1
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.8	-0.2	0.2	0.0	0.3	0.2	-0.9	-0.3	-0.0	0.4	-0.4	-0.1	-0.3
Qualifications: CSEs or equivalent	0.1	0.1	0.5	-0.1	0.2	0.0	-0.1	0.3	-0.0	-0.1	-0.6	-0.1	-0.5	-0.3	-0.7
High blood pressure	0.1	0.2	0.3	0.4	-0.6	-0.4	0.4	-0.4	0.3	-0.5	-0.3	0.1	-0.5	-0.5	-0.2
Forced vital capacity (FVC)	0.1	0.4	1.5	-1.2	-0.5	-0.0	0.6	0.1	-1.0	-0.7	-0.1	-0.6	-0.2	-0.4	-1.1
Qualifications: None of the above	0.1	0.2	0.8	-0.7	0.9	0.7	0.3	0.7	0.2	0.0	0.1	0.3	0.0	0.2	-0.5
Medication: Ramipril	0.1	0.2	0.4	0.3	0.4	0.3	0.5	0.4	0.4	0.4	0.3	0.6	0.3	0.1	0.6
Forced expiratory volume in 1-second (FEV1)	0.1	0.5	1.7	-1.3	-0.1	0.4	1.0	0.5	-0.9	-0.5	-0.1	-0.2	-0.1	-0.1	-1.1
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.2	0.3	0.2	0.0	0.3	0.2	0.3	0.2	-0.0	0.4	-0.0	0.2	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	0.5	-0.7	-0.1	0.4	0.7	0.4	-0.1	0.2	0.6	0.3	0.5	0.4	0.1
Standing height	0.1	1.3	5.2	-2.3	-0.1	0.9	1.1	0.9	-1.7	-1.0	0.7	-0.6	1.4	-0.6	-0.6
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.6	0.4	-0.2	-0.2	-0.7	-0.2	0.2	0.6	0.3	0.1	0.1	0.2	0.3
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.6	-0.6	0.3	0.7	0.5	0.8	-0.0	0.1	0.4	0.1	0.3	0.5	-0.2
Birth weight	0.1	0.1	0.9	-0.9	0.2	-0.2	0.0	-0.4	-0.0	-0.6	-0.2	-0.5	0.0	-0.0	-0.1
Body fat percentage	0.1	0.4	2.4	-0.0	1.6	0.7	0.6	0.5	0.4	-0.0	-0.1	0.9	0.6	0.2	0.6
Comparative body size at age 10	0.1	0.2	1.0	0.4	0.0	-0.2	-1.0	0.1	0.5	0.6	-0.4	0.2	-0.7	0.2	-0.3
Medication for pain relief, constipation, heartburn	0.1	0.2	0.8	-0.8	-0.4	0.1	-0.1	0.4	-0.3	-0.3	0.0	-0.3	-0.1	-0.5	-0.9
Angina (self-reported)	0.1	0.1	0.2	-0.3	0.5	0.1	-0.3	0.1	0.1	0.1	-0.4	-0.3	-0.0	-0.3	-0.4
Pulse rate, automated reading	0.1	0.2	0.8	0.1	-0.0	-0.0	0.9	0.1	-0.5	-0.7	-0.5	0.1	0.2	-0.3	0.6
Hypertension (Self-reported)	0.1	0.3	0.7	0.2	-0.7	-0.6	0.4	-0.5	0.0	-0.8	-0.6	-0.2	-0.6	-0.9	-0.6
Breast cancer (self-reported)	0.1	0.2	0.4	0.1	-0.4	-0.5	0.1	-0.5	0.6	-0.1	-0.2	-0.6	-0.7	0.0	-0.5
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.7	0.8	0.0	0.2	-0.8	0.1	0.1	0.3	0.4	0.5	0.2	-0.2	0.6
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.5	-0.2	-0.5	-0.1	0.7	0.1	-0.6	-0.7	-0.0	-0.1	-0.4	0.1	-0.4
Unable to work because of sickness or disability	0.1	0.1	0.4	0.2	0.3	0.2	-0.3	0.2	-0.4	-0.2	-0.4	-0.4	-0.1	-0.6	-0.4
Supplements: Calcium	0.1	0.1	0.5	-0.1	-0.0	0.1	0.6	0.2	-0.1	-0.3	0.3	0.4	-0.7	0.5	-0.4
Alcohol drinker status: Previous	0.1	0.1	0.2	0.1	0.2	0.1	0.1	0.3	0.2	0.1	-0.3	0.2	-0.5	0.3	-0.4
Verbal and Numeric Reasoning (VNR)	0.0	0.1	0.2	0.4	0.1	-0.1	-0.3	-0.0	0.4	0.2	0.3	0.1	0.1	-0.4	0.4
Blood Platelet Count	0.0	0.5	1.5	-0.8	1.2	1.1	0.6	1.1	-0.4	-0.1	-0.1	0.5	0.5	0.0	-0.3
Heel T-Score	0.0	0.3	0.6	-0.2	0.7	0.5	0.3	0.7	0.6	0.2	0.8	0.6	0.1	0.4	0.1
Cardiovascular Disease	0.0	0.1	0.4	0.1	0.1	-0.1	0.6	-0.0	-0.3	-0.6	-0.5	0.3	-0.4	-0.5	-0.4
Lung FVC	0.0	0.2	0.4	0.6	-0.6	-0.5	0.2	-0.5	0.5	-0.2	0.1	0.2	-0.5	-0.1	0.4
Chronotype (morning person)	0.0	0.1	0.4	-0.6	-0.1	-0.1	0.2	-0.1	0.4	0.3	0.5	-0.0	-0.1	0.2	-0.2
Angina	0.0	0.1	0.2	-0.3	0.4	0.1	-0.3	0.1	0.1	0.1	-0.3	-0.3	0.0	-0.2	-0.4
Medication: Atenolol	0.0	0.0	0.2	-0.2	0.3	0.2	0.1	0.1	-0.1	-0.2	-0.1	-0.3	0.5	-0.3	-0.0
Fluid intelligence score	0.0	0.0	0.2	0.2	0.1	-0.0	-0.3	-0.0	0.2	0.1	0.0	0.2	0.2	-0.2	0.4
Forced vital capacity (FVC), Best measure	0.0	0.1	0.7	-0.3	-0.5	0.1	-0.2	0.1	0.3	0.4	0.8	0.1	0.3	0.3	0.2
Vascular/heart problems diagnosed by doctor	0.0	0.1	0.3	-0.5	0.0	0.2	-0.5	0.1	-0.0	0.4	0.1	-0.2	0.2	0.6	-0.0

Hub : Genes

NOL10

Models

Trait associations