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Prostate Cancer
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chr3:86,583,852-87,999,964
Best TWAS P=8.71e-16 · Best GWAS P=8.52e-21 conditioned to 5.29e-07
86.6M
86.8M
87M
87.2M
87.4M
87.6M
87.8M
88M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
METSIM
Adipose
CHMP2B
0.07
0.04
lasso
2
0.03
7.4e-05
8.1
8.0
8.7e-16
0.75
0.51
0.22
TRUE
3
YFS
Blood
CHMP2B
0.23
0.11
enet
30
0.16
5.4e-51
4.1
7.3
1.9e-13
0.60
1.00
0.00
FALSE
1
GTEx
Esophagus Mucosa
CHMP2B
0.18
0.12
enet
26
0.16
1.6e-10
5.0
7.1
1.0e-12
0.78
0.91
0.09
FALSE