Best TWAS P=8.71e-16 · Best GWAS P=8.52e-21 conditioned to 5.29e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | CHMP2B | 0.18 | 0.12 | enet | 26 | 0.16 | 1.6e-10 | 5.0 | 7.1 | 1.0e-12 | 0.78 | 0.91 | 0.09 | FALSE |
| 2 | METSIM | Adipose | CHMP2B | 0.07 | 0.04 | lasso | 2 | 0.03 | 7.4e-05 | 8.1 | 8.0 | 8.7e-16 | 0.75 | 0.51 | 0.22 | TRUE |
| 3 | YFS | Blood | CHMP2B | 0.23 | 0.11 | enet | 30 | 0.16 | 5.4e-51 | 4.1 | 7.3 | 1.9e-13 | 0.60 | 1.00 | 0.00 | FALSE |