[Hub]/) : Traits : Prostate Cancer :

chr3:112,317,291-114,043,692

Best TWAS P=7.15e-12 · Best GWAS P=3.84e-09 conditioned to 0.587

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous WDR52 0.09 0.07 lasso 7 0.09 1.1e-07 -5.4 5.2 2.6e-07 -0.64 0.41 0.58 FALSE
2 GTEx Adipose Visceral Omentum WDR52 0.13 0.07 enet 20 0.07 2.1e-04 -5.4 5.2 1.5e-07 -0.64 0.07 0.90 FALSE
3 GTEx Artery Tibial WDR52 0.07 0.08 lasso 3 0.07 2.8e-06 -5.2 5.2 2.5e-07 -0.65 0.47 0.39 FALSE
4 GTEx Cells EBV-transformed lymphocytes WDR52 0.22 -0.01 lasso 9 0.00 3.5e-01 -3.4 5.6 2.0e-08 -0.37 0.08 0.16 FALSE
5 GTEx Colon Transverse WDR52 0.27 0.07 enet 25 0.12 3.7e-06 -5.6 5.4 6.9e-08 -0.46 0.59 0.15 FALSE
6 GTEx Esophagus Mucosa SIDT1 0.36 0.31 enet 21 0.33 6.2e-23 5.1 -5.7 1.5e-08 0.70 0.99 0.01 FALSE
7 GTEx Esophagus Muscularis WDR52 0.08 0.03 enet 14 0.03 7.5e-03 -5.7 5.5 4.6e-08 -0.51 0.09 0.75 FALSE
8 GTEx Nerve Tibial WDR52 0.12 0.03 lasso 10 0.02 9.1e-03 -5.6 5.9 4.6e-09 -0.49 0.48 0.24 FALSE
9 GTEx Ovary WDR52 0.21 0.26 lasso 9 0.23 1.9e-06 -7.1 6.8 7.2e-12 -0.81 0.00 0.99 TRUE
10 GTEx Skin Not Sun Exposed Suprapubic WDR52 0.11 0.07 lasso 13 0.11 9.0e-07 -5.2 5.7 1.1e-08 -0.41 0.74 0.09 FALSE
11 GTEx Skin Sun Exposed Lower leg WDR52 0.12 0.06 enet 22 0.05 1.0e-04 -5.6 5.7 1.1e-08 -0.55 0.67 0.20 FALSE
12 GTEx Testis SPICE1 0.24 0.01 lasso 8 0.03 2.2e-02 -4.6 -5.7 1.5e-08 0.45 0.10 0.26 FALSE
13 GTEx Thyroid WDR52 0.11 0.06 lasso 9 0.09 1.2e-07 -5.6 5.7 1.2e-08 -0.51 0.91 0.08 FALSE
14 NTR Blood SIDT1 0.04 0.05 lasso 3 0.05 5.6e-15 5.2 -5.2 2.3e-07 0.64 0.99 0.01 FALSE
15 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SIDT1 0.05 0.01 blup 87 0.03 1.1e-04 6.6 -5.8 7.2e-09 0.75 0.04 0.89 FALSE