[Hub]/) : Traits : Prostate Cancer : ← →

chr2:84,884,961-86,518,249

Best TWAS P=2.5e-12 · Best GWAS P=9.23e-11 conditioned to 0.829

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Brain Nucleus accumbens basal ganglia	GGCX	0.28	0.09	enet	7	0.02	7.6e-02	-6.5	-7.0	2.5e-12	0.94	0.02	0.87	TRUE
38	The Cancer Genome Atlas	Lung Adenocarcinoma	USP39	0.04	0.02	blup	67	0.03	2.0e-04	-6.5	6.9	6.8e-12	-0.81	0.01	0.98	FALSE
34	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	VAMP8	0.06	0.06	enet	6	0.07	1.8e-06	-5.4	6.8	1.1e-11	-0.85	0.06	0.93	FALSE
11	GTEx	Cells EBV-transformed lymphocytes	GGCX	0.36	0.31	enet	18	0.29	4.5e-10	-6.4	-6.7	2.1e-11	0.95	0.01	0.99	FALSE
10	GTEx	Breast Mammary Tissue (Male)	GGCX	0.10	0.00	enet	4	0.00	3.3e-01	-6.4	-6.7	2.4e-11	0.96	0.02	0.62	FALSE
29	NTR	Blood	VAMP8	0.05	0.04	lasso	8	0.04	2.0e-12	-6.6	6.6	3.1e-11	-0.90	0.01	0.99	FALSE
36	The Cancer Genome Atlas	Brain Lower Grade Glioma	VAMP5	0.06	0.04	lasso	2	0.04	3.2e-05	-6.6	6.6	3.2e-11	-0.96	0.00	0.99	FALSE
23	GTEx	Skin Not Sun Exposed Suprapubic	GGCX	0.13	0.04	enet	11	0.06	3.9e-04	-6.5	-6.6	3.7e-11	0.74	0.01	0.96	FALSE
5	GTEx	Brain Cerebellar Hemisphere	GGCX	0.46	0.41	enet	16	0.48	5.3e-14	-6.5	-6.6	4.9e-11	0.94	0.01	0.99	FALSE
9	GTEx	Breast Mammary Tissue	GGCX	0.14	0.01	lasso	3	0.01	1.0e-01	-6.5	-6.6	4.9e-11	0.93	0.02	0.89	FALSE
14	GTEx	Esophagus Mucosa	GGCX	0.29	0.21	enet	30	0.27	5.8e-18	-6.4	-6.6	4.9e-11	0.83	0.01	0.99	FALSE
41	The Cancer Genome Atlas	Thyroid Carcinoma	VAMP8	0.04	0.05	lasso	3	0.05	1.2e-05	-6.4	6.6	4.9e-11	-0.90	0.01	0.99	FALSE
19	GTEx	Lung	GGCX	0.17	0.17	lasso	2	0.18	2.3e-13	-6.5	-6.5	7.2e-11	0.88	0.01	0.99	FALSE
27	GTEx	Whole Blood	GGCX	0.15	0.14	lasso	4	0.15	1.7e-13	-6.5	-6.5	9.4e-11	0.90	0.01	0.99	FALSE
28	METSIM	Adipose	GGCX	0.07	0.09	lasso	8	0.09	9.6e-14	-6.4	-6.5	1.0e-10	0.94	0.02	0.98	FALSE
12	GTEx	Colon Transverse	GGCX	0.26	0.28	lasso	3	0.28	1.4e-13	-6.5	-6.4	1.3e-10	0.88	0.01	0.99	FALSE
32	YFS	Blood	VAMP8	0.15	0.15	enet	37	0.18	2.2e-55	-6.4	6.4	1.4e-10	-0.89	0.01	0.99	FALSE
17	GTEx	Esophagus Muscularis	GGCX	0.14	0.12	lasso	9	0.12	1.1e-07	-6.6	-6.4	1.6e-10	0.92	0.01	0.99	FALSE
37	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	USP39	0.10	0.07	blup	62	0.04	7.1e-03	-4.3	6.3	2.4e-10	-0.63	0.04	0.21	FALSE
30	ROSMAP	Brain Pre-frontal Cortex	GGCX	0.12	0.10	lasso	4	0.12	5.4e-15	-6.3	-6.3	3.2e-10	0.90	0.02	0.98	FALSE
20	GTEx	Muscle Skeletal	GGCX	0.10	0.04	enet	11	0.02	2.7e-03	-6.6	-6.3	3.6e-10	0.89	0.01	0.99	FALSE
22	GTEx	Prostate	GGCX	0.31	0.16	lasso	4	0.20	1.0e-05	-6.5	-6.3	4.0e-10	0.93	0.02	0.92	FALSE
25	GTEx	Testis	GGCX	0.38	0.36	enet	25	0.40	8.6e-19	-6.5	-6.2	4.2e-10	0.84	0.01	0.99	FALSE
1	GTEx	Adipose Subcutaneous	GGCX	0.16	0.09	lasso	5	0.08	3.1e-07	-6.5	-6.2	4.8e-10	0.88	0.01	0.99	FALSE
6	GTEx	Brain Cerebellum	GGCX	0.54	0.30	lasso	10	0.34	6.0e-11	-6.5	-6.2	5.3e-10	0.90	0.01	0.99	FALSE
13	GTEx	Esophagus Gastroesophageal Junction	GGCX	0.24	0.16	lasso	6	0.12	4.3e-05	-6.5	-6.2	5.8e-10	0.86	0.01	0.98	FALSE
33	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	USP39	0.04	0.00	blup	68	0.01	1.8e-02	-4.0	6.2	6.2e-10	-0.75	0.02	0.57	FALSE
2	GTEx	Adipose Visceral Omentum	GGCX	0.13	0.03	lasso	7	0.03	1.1e-02	-6.6	-6.2	7.7e-10	0.88	0.01	0.97	FALSE
3	GTEx	Artery Aorta	GGCX	0.23	0.22	lasso	6	0.23	5.5e-13	-6.6	-6.1	1.1e-09	0.86	0.01	0.99	FALSE
16	GTEx	Esophagus Mucosa	TMEM150A	0.10	0.05	enet	5	0.05	3.2e-04	-6.5	6.1	1.1e-09	-0.91	0.01	0.97	FALSE
21	GTEx	Nerve Tibial	GGCX	0.38	0.30	lasso	7	0.33	6.5e-24	-6.4	-6.1	1.2e-09	0.87	0.01	0.99	FALSE
15	GTEx	Esophagus Mucosa	VAMP8	0.41	0.31	lasso	6	0.36	6.6e-25	-6.5	6.0	1.5e-09	-0.84	0.01	0.99	FALSE
7	GTEx	Brain Cortex	GGCX	0.38	0.17	enet	30	0.02	1.1e-01	-6.5	-6.0	1.6e-09	0.81	0.01	0.98	FALSE
26	GTEx	Thyroid	GGCX	0.30	0.17	enet	10	0.23	1.4e-17	-6.5	-6.0	1.6e-09	0.84	0.01	0.99	FALSE
35	The Cancer Genome Atlas	Breast Invasive Carcinoma	USP39	0.02	0.00	blup	67	0.01	1.7e-03	-3.5	5.9	3.2e-09	-0.75	0.05	0.55	FALSE
4	GTEx	Artery Tibial	GGCX	0.29	0.22	enet	14	0.24	6.3e-19	-6.4	-5.9	3.3e-09	0.85	0.01	0.99	FALSE
18	GTEx	Lung	ELMOD3	0.14	0.00	enet	21	0.01	5.5e-02	-2.7	5.7	1.2e-08	-0.33	0.20	0.23	FALSE
24	GTEx	Skin Sun Exposed Lower leg	GGCX	0.15	0.11	lasso	3	0.18	7.9e-15	-6.5	-5.5	3.4e-08	0.76	0.01	0.99	FALSE
39	The Cancer Genome Atlas	Lung Adenocarcinoma	VAMP8	0.07	0.07	blup	43	0.06	4.8e-08	-5.2	5.4	6.1e-08	-0.68	0.31	0.68	FALSE
40	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	VAMP8	0.05	0.04	lasso	3	0.03	2.0e-04	-5.2	5.3	1.1e-07	-0.65	0.26	0.67	FALSE
31	ROSMAP	Brain Pre-frontal Cortex	VAMP8	0.06	0.05	lasso	2	0.04	1.8e-06	-5.2	5.2	2.1e-07	-0.68	0.72	0.26	FALSE