Best TWAS P=1.85e-09 · Best GWAS P=2.06e-08 conditioned to 0.0202
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | PBX3 | 0.17 | 0.08 | lasso | 6 | 0.10 | 2.4e-08 | -5.6 | -5.2 | 1.6e-07 | 0.94 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | MAPKAP1 | 0.04 | 0.03 | lasso | 3 | 0.02 | 6.5e-03 | 4.9 | 5.2 | 1.7e-07 | -0.54 | 0.12 | 0.78 | FALSE |
| 3 | GTEx | Esophagus Muscularis | PBX3 | 0.12 | 0.08 | lasso | 7 | 0.09 | 4.2e-06 | -4.6 | -5.1 | 3.0e-07 | 0.87 | 0.03 | 0.97 | FALSE |
| 4 | YFS | Blood | PBX3 | 0.05 | 0.03 | enet | 18 | 0.03 | 5.6e-11 | -4.3 | 6.0 | 1.9e-09 | -0.63 | 0.66 | 0.32 | TRUE |