[Hub]/) : Traits : Blood Red Count :

chr9:114,119,984-117,058,254

Best TWAS P=4.96e-15 · Best GWAS P=2.26e-17 conditioned to 6.08e-17

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RGS3 0.11 0.01 blup 653 0.05 7.2e-07 -6.8 6.0 2.7e-09 -0.03 0.11 0.86 FALSE
2 CommonMind Brain Pre-frontal Cortex SLC46A2 0.25 0.08 lasso 8 0.14 6.0e-17 -4.9 5.5 2.9e-08 -0.02 0.03 0.97 FALSE
3 GTEx Adipose Subcutaneous C9orf43 0.06 0.05 lasso 3 0.05 9.0e-05 -7.6 7.8 5.0e-15 -0.01 0.02 0.97 TRUE
4 GTEx Adipose Visceral Omentum C9orf43 0.12 0.08 lasso 10 0.06 3.0e-04 -7.2 7.2 6.7e-13 -0.03 0.08 0.90 FALSE
5 GTEx Brain Cortex RP11-4O1.2 0.44 0.00 enet 43 0.07 5.0e-03 3.1 -6.5 6.0e-11 0.34 0.12 0.09 FALSE
6 GTEx Cells EBV-transformed lymphocytes PTBP3 0.18 0.01 lasso 2 -0.01 6.4e-01 -5.7 5.8 9.1e-09 -0.06 0.13 0.04 FALSE
7 GTEx Cells EBV-transformed lymphocytes C9orf43 0.20 0.21 lasso 2 0.18 2.4e-06 -7.1 7.2 8.9e-13 -0.04 0.10 0.89 FALSE
8 GTEx Cells Transformed fibroblasts C9orf43 0.13 0.09 enet 31 0.11 1.6e-08 -7.1 6.4 2.0e-10 -0.02 0.12 0.88 FALSE
9 GTEx Esophagus Mucosa C9orf43 0.13 0.13 lasso 4 0.12 1.4e-08 -7.1 7.3 2.5e-13 -0.04 0.09 0.91 FALSE
10 GTEx Muscle Skeletal ALAD 0.08 0.03 enet 18 0.06 6.2e-07 2.6 -5.3 1.2e-07 -0.09 0.76 0.01 TRUE
11 GTEx Stomach C9orf43 0.11 0.01 enet 13 0.03 1.3e-02 -7.1 6.5 6.8e-11 0.00 0.06 0.90 FALSE
12 GTEx Testis C9orf43 0.52 0.59 enet 31 0.65 3.4e-37 -7.1 6.2 5.9e-10 -0.04 0.11 0.89 FALSE
13 METSIM Adipose C9orf43 0.05 0.05 lasso 1 0.03 5.8e-06 -7.0 7.0 1.9e-12 -0.04 0.11 0.89 FALSE
14 The Cancer Genome Atlas Bladder Urothelial Carcinoma C9orf43 0.10 0.12 lasso 1 0.12 2.0e-10 -6.8 6.8 8.3e-12 -0.03 0.03 0.97 FALSE
15 The Cancer Genome Atlas Breast Invasive Carcinoma C9orf43 0.08 0.10 lasso 3 0.10 2.5e-20 -7.2 7.3 2.0e-13 -0.02 0.02 0.98 FALSE
16 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma C9orf43 0.10 0.06 lasso 6 0.06 1.0e-03 -6.8 6.8 1.3e-11 -0.01 0.02 0.90 FALSE
17 The Cancer Genome Atlas Colon Adenocarcinoma C9orf43 0.19 0.17 enet 9 0.16 1.2e-09 -7.2 7.1 1.5e-12 -0.03 0.02 0.98 FALSE
18 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C9orf43 0.12 0.13 lasso 2 0.13 5.2e-14 -7.2 7.2 6.7e-13 -0.03 0.03 0.97 FALSE
19 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SUSD1 0.06 0.04 enet 7 0.06 5.9e-07 -7.4 -7.3 2.8e-13 0.38 0.18 0.16 FALSE
20 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C9orf43 0.09 0.10 lasso 2 0.09 5.9e-10 -6.8 7.0 2.0e-12 -0.03 0.03 0.97 FALSE
21 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma C9orf43 0.13 0.08 blup 57 0.07 4.9e-05 -7.2 6.1 1.2e-09 0.00 0.03 0.96 FALSE
22 The Cancer Genome Atlas Brain Lower Grade Glioma C9orf43 0.07 0.05 lasso 5 0.05 5.8e-06 -7.2 7.1 1.7e-12 -0.04 0.02 0.98 FALSE
23 The Cancer Genome Atlas Lung Adenocarcinoma C9orf43 0.12 0.16 enet 5 0.16 6.9e-18 -7.2 7.2 4.5e-13 -0.03 0.02 0.98 FALSE
24 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C9orf43 0.21 0.19 blup 58 0.19 7.5e-21 -6.8 7.0 3.0e-12 -0.02 0.03 0.97 FALSE
25 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C9orf43 0.11 0.08 lasso 5 0.06 3.8e-05 -6.8 6.9 5.3e-12 -0.03 0.02 0.97 FALSE
26 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma SUSD1 0.10 0.04 enet 9 0.08 5.5e-06 3.1 -6.8 1.4e-11 0.17 0.83 0.01 FALSE
27 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma C9orf43 0.26 0.26 lasso 4 0.23 1.0e-09 -6.8 7.0 2.4e-12 -0.03 0.03 0.97 FALSE
28 The Cancer Genome Atlas Prostate Adenocarcinoma C9orf43 0.18 0.24 enet 6 0.24 4.3e-25 -6.8 7.5 8.4e-14 -0.03 0.03 0.97 FALSE
29 The Cancer Genome Atlas Prostate Adenocarcinoma RGS3 0.04 0.04 lasso 2 0.03 2.5e-04 -6.4 6.6 3.9e-11 -0.01 0.18 0.47 FALSE
30 The Cancer Genome Atlas Prostate Adenocarcinoma SNX30 0.05 0.04 lasso 3 0.04 1.3e-04 -6.8 -6.9 7.0e-12 -0.01 0.00 1.00 TRUE
31 The Cancer Genome Atlas Prostate Adenocarcinoma SUSD1 0.09 0.02 blup 122 0.03 5.7e-04 -7.5 -7.5 9.1e-14 0.08 0.12 0.04 TRUE
32 The Cancer Genome Atlas Rectum Adenocarcinoma C9orf43 0.49 0.17 enet 6 0.14 4.7e-04 -6.8 7.2 5.9e-13 -0.03 0.02 0.73 FALSE
33 The Cancer Genome Atlas Soft Tissue Sarcoma C9orf43 0.11 0.10 lasso 5 0.09 4.9e-06 -7.2 7.2 6.9e-13 -0.04 0.02 0.96 FALSE
34 The Cancer Genome Atlas Soft Tissue Sarcoma HDHD3 0.11 0.00 enet 11 0.04 1.9e-03 -2.9 -5.4 6.9e-08 0.00 0.01 0.74 FALSE
35 The Cancer Genome Atlas Skin Cutaneous Melanoma C9orf43 0.30 0.17 lasso 4 0.16 4.9e-05 -7.6 7.7 1.2e-14 -0.01 0.00 0.99 FALSE
36 The Cancer Genome Atlas Stomach Adenocarcinoma C9orf43 0.11 0.06 lasso 5 0.05 1.7e-04 -6.8 7.7 1.8e-14 -0.02 0.01 0.99 FALSE
37 The Cancer Genome Atlas Stomach Adenocarcinoma SUSD1 0.07 0.00 blup 121 0.02 1.3e-02 3.1 -7.3 3.3e-13 0.46 0.04 0.15 FALSE
38 The Cancer Genome Atlas Testicular Germ Cell Tumors C9orf43 0.13 0.15 enet 6 0.13 2.3e-05 -6.8 7.2 8.2e-13 -0.03 0.01 0.95 FALSE
39 The Cancer Genome Atlas Thyroid Carcinoma C9orf43 0.13 0.11 blup 57 0.16 3.7e-15 -7.6 7.7 1.9e-14 0.01 0.00 1.00 FALSE