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chr11:198,510-1,075,920

Best TWAS P=1.42e-11 · Best GWAS P=2.53e-07 conditioned to 0.303

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IFITM3	0.04	0.02	blup	57	0.02	4.7e-03	-4.62	6.8	1.4e-11	-0.69	0.01	0.28	TRUE
4	GTEx	Skin Sun Exposed Lower leg	B4GALNT4	0.11	0.01	lasso	4	0.01	4.8e-02	2.59	5.4	5.3e-08	-0.04	0.04	0.15	TRUE
8	The Cancer Genome Atlas	Breast Invasive Carcinoma	SIRT3	0.04	0.01	blup	76	0.03	2.0e-06	0.29	5.2	1.5e-07	0.08	0.02	0.77	TRUE
7	GTEx	Whole Blood	IFITM3	0.09	0.02	enet	12	0.07	5.2e-07	4.22	6.2	8.0e-10	-0.43	0.10	0.50	FALSE
5	GTEx	Skin Sun Exposed Lower leg	RP11-326C3.11	0.33	0.08	lasso	6	0.07	1.4e-06	-5.16	5.6	1.8e-08	-0.96	0.00	0.99	FALSE
6	GTEx	Skin Sun Exposed Lower leg	RP11-326C3.12	0.09	0.02	enet	9	0.05	7.1e-05	-4.62	-5.6	1.8e-08	0.71	0.01	0.97	FALSE
9	The Cancer Genome Atlas	Colon Adenocarcinoma	IFITM3	0.10	0.03	blup	57	0.02	1.8e-02	1.93	5.4	6.4e-08	-0.70	0.00	0.59	FALSE
11	The Cancer Genome Atlas	Brain Lower Grade Glioma	IFITM3	0.06	0.01	blup	57	0.03	1.2e-04	4.37	5.4	6.5e-08	-0.56	0.04	0.79	FALSE
2	GTEx	Brain Hypothalamus	RP11-326C3.12	0.39	0.26	lasso	4	0.26	7.7e-07	-5.16	-5.3	1.4e-07	0.96	0.00	0.98	FALSE
1	GTEx	Adipose Subcutaneous	RP11-326C3.11	0.40	0.17	lasso	7	0.17	1.1e-13	4.37	5.2	2.5e-07	-0.77	0.08	0.88	FALSE
3	GTEx	Cells EBV-transformed lymphocytes	RP11-326C3.7	0.34	0.08	enet	25	0.15	1.7e-05	-4.62	-5.1	2.8e-07	0.43	0.02	0.70	FALSE