[Hub]/) : Traits : Blood Red Count :

chr11:198,510-1,075,920

Best TWAS P=1.42e-11 · Best GWAS P=2.53e-07 conditioned to 0.303

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP11-326C3.11 0.40 0.17 lasso 7 0.17 1.1e-13 4.37 5.2 2.5e-07 -0.77 0.08 0.88 FALSE
2 GTEx Brain Hypothalamus RP11-326C3.12 0.39 0.26 lasso 4 0.26 7.7e-07 -5.16 -5.3 1.4e-07 0.96 0.00 0.98 FALSE
3 GTEx Cells EBV-transformed lymphocytes RP11-326C3.7 0.34 0.08 enet 25 0.15 1.7e-05 -4.62 -5.1 2.8e-07 0.43 0.02 0.70 FALSE
4 GTEx Skin Sun Exposed Lower leg B4GALNT4 0.11 0.01 lasso 4 0.01 4.8e-02 2.59 5.4 5.3e-08 -0.04 0.04 0.15 TRUE
5 GTEx Skin Sun Exposed Lower leg RP11-326C3.11 0.33 0.08 lasso 6 0.07 1.4e-06 -5.16 5.6 1.8e-08 -0.96 0.00 0.99 FALSE
6 GTEx Skin Sun Exposed Lower leg RP11-326C3.12 0.09 0.02 enet 9 0.05 7.1e-05 -4.62 -5.6 1.8e-08 0.71 0.01 0.97 FALSE
7 GTEx Whole Blood IFITM3 0.09 0.02 enet 12 0.07 5.2e-07 4.22 6.2 8.0e-10 -0.43 0.10 0.50 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma SIRT3 0.04 0.01 blup 76 0.03 2.0e-06 0.29 5.2 1.5e-07 0.08 0.02 0.77 TRUE
9 The Cancer Genome Atlas Colon Adenocarcinoma IFITM3 0.10 0.03 blup 57 0.02 1.8e-02 1.93 5.4 6.4e-08 -0.70 0.00 0.59 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma IFITM3 0.04 0.02 blup 57 0.02 4.7e-03 -4.62 6.8 1.4e-11 -0.69 0.01 0.28 TRUE
11 The Cancer Genome Atlas Brain Lower Grade Glioma IFITM3 0.06 0.01 blup 57 0.03 1.2e-04 4.37 5.4 6.5e-08 -0.56 0.04 0.79 FALSE