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chr11:29,713,564-32,824,150

Best TWAS P=2.26e-29 · Best GWAS P=4.2e-32 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
16	GTEx	Testis	MPPED2	0.18	0.17	enet	15	0.17	6.9e-08	-10.9	-11.3	2.3e-29	-0.20	0.85	0.14	TRUE
9	GTEx	Breast Mammary Tissue (Female)	ELP4	0.26	0.12	lasso	5	0.07	5.2e-03	-10.4	10.2	2.0e-24	0.24	0.01	0.96	TRUE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	IMMP1L	0.05	0.01	blup	40	0.00	1.8e-01	-8.6	9.4	7.4e-21	0.22	0.00	0.71	TRUE
7	GTEx	Breast Mammary Tissue	IMMP1L	0.08	0.01	enet	18	0.00	2.1e-01	-8.5	8.8	1.5e-18	0.21	0.04	0.74	TRUE
1	CommonMind	Brain Pre-frontal Cortex	DNAJC24	0.04	0.01	blup	279	0.02	4.0e-03	6.7	-7.2	5.3e-13	-0.17	0.43	0.04	TRUE
19	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DNAJC24	0.05	0.02	lasso	3	0.02	6.7e-03	6.7	6.7	2.5e-11	0.19	0.12	0.08	TRUE
4	GTEx	Adrenal Gland	MPPED2	0.43	0.33	lasso	9	0.30	1.5e-11	-5.4	-5.8	9.1e-09	-0.03	1.00	0.00	TRUE
10	GTEx	Cells Transformed fibroblasts	RP1-65P5.3	0.18	0.08	enet	15	0.12	2.5e-09	3.5	-5.7	1.5e-08	-0.07	0.99	0.01	TRUE
20	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ELP4	0.05	0.00	blup	106	0.02	5.6e-03	-3.3	5.5	4.5e-08	0.11	0.02	0.38	TRUE
11	GTEx	Colon Transverse	DNAJC24	0.07	0.02	enet	13	0.05	2.5e-03	2.2	-5.2	1.9e-07	-0.08	0.12	0.07	TRUE
6	GTEx	Breast Mammary Tissue	ELP4	0.09	0.04	lasso	5	0.05	1.8e-03	7.7	9.6	5.2e-22	0.22	0.02	0.86	FALSE
14	GTEx	Nerve Tibial	MPPED2	0.07	0.00	enet	7	0.01	8.7e-02	-11.3	-9.1	1.2e-19	-0.13	0.16	0.16	FALSE
12	GTEx	Muscle Skeletal	MPPED2	0.09	0.07	lasso	3	0.06	2.4e-06	-9.3	8.2	1.6e-16	0.18	0.99	0.00	FALSE
18	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	IMMP1L	0.11	0.02	blup	40	0.03	1.0e-02	4.8	8.0	1.3e-15	0.19	0.02	0.56	FALSE
8	GTEx	Breast Mammary Tissue (Male)	IMMP1L	0.15	0.01	lasso	7	0.00	4.1e-01	7.7	7.1	1.3e-12	0.21	0.04	0.22	FALSE
23	The Cancer Genome Atlas	Lung Adenocarcinoma	IMMP1L	0.04	0.02	blup	40	0.02	2.0e-03	4.7	7.0	1.8e-12	0.16	0.08	0.37	FALSE
22	The Cancer Genome Atlas	Lung Adenocarcinoma	DNAJC24	0.03	0.02	blup	31	0.01	3.8e-02	6.6	6.8	9.9e-12	0.21	0.05	0.11	FALSE
2	GTEx	Adipose Subcutaneous	ELP4	0.07	0.04	lasso	3	0.04	5.8e-04	6.6	6.7	2.7e-11	0.19	0.84	0.04	FALSE
3	GTEx	Adipose Visceral Omentum	ELP4	0.10	0.12	enet	7	0.12	8.8e-07	6.6	6.7	3.0e-11	0.19	0.90	0.04	FALSE
21	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	IMMP1L	0.04	0.02	lasso	1	0.01	1.1e-02	6.6	6.6	4.5e-11	0.19	0.02	0.08	FALSE
15	GTEx	Nerve Tibial	DNAJC24	0.05	0.04	lasso	4	0.02	2.0e-02	6.7	-6.5	9.6e-11	-0.18	0.26	0.04	FALSE
17	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	DNAJC24	0.05	0.01	blup	31	0.01	9.4e-02	6.5	6.4	1.7e-10	0.21	0.02	0.11	FALSE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	ELP4	0.03	0.03	enet	3	0.03	9.7e-04	-6.2	6.0	1.4e-09	0.07	0.07	0.71	FALSE
5	GTEx	Artery Tibial	DNAJC24	0.05	0.05	enet	13	0.03	2.6e-03	6.7	-5.6	2.0e-08	-0.15	0.47	0.02	FALSE
13	GTEx	Muscle Skeletal	DNAJC24	0.08	0.06	enet	12	0.05	9.1e-06	6.5	-5.5	3.7e-08	-0.16	0.99	0.00	FALSE