Best TWAS P=1.59e-12 · Best GWAS P=8.22e-11 conditioned to 0.00729
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ACVRL1 | 0.03 | 0.00 | blup | 47 | 0.01 | 2.5e-03 | 6.5 | -7.1 | 1.6e-12 | -0.60 | 0.00 | 0.81 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ACVRL1 | 0.09 | 0.00 | blup | 46 | 0.03 | 9.4e-05 | -1.9 | -6.3 | 3.1e-10 | -0.20 | 0.01 | 0.06 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | FIGNL2 | 0.07 | 0.06 | enet | 7 | 0.07 | 6.2e-08 | -4.2 | 5.2 | 1.7e-07 | 0.02 | 0.03 | 0.88 | TRUE |