[Hub]/) : Traits : Blood Red Count :

chr12:47,358,286-49,876,065

Best TWAS P=1.04e-43 · Best GWAS P=3.09e-38 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SENP1 0.05 0.02 blup 555 0.04 1.7e-05 -10.45 10.2 1.4e-24 0.39 0.78 0.22 FALSE
2 CommonMind Brain Pre-frontal Cortex TMEM106C 0.13 0.06 enet 21 0.11 3.2e-13 -8.33 -6.2 7.7e-10 -0.20 1.00 0.00 FALSE
3 CommonMind Brain Pre-frontal Cortex ZNF641 0.03 0.01 blup 489 0.02 6.4e-04 -10.50 -9.9 3.1e-23 -0.50 0.28 0.47 FALSE
4 GTEx Adipose Subcutaneous ZNF641 0.10 0.10 lasso 4 0.10 2.8e-08 -10.36 -10.4 2.0e-25 -0.42 1.00 0.00 FALSE
5 GTEx Adipose Subcutaneous RP1-228P16.1 0.20 0.20 lasso 8 0.22 4.7e-18 -8.93 10.3 4.2e-25 0.44 1.00 0.00 FALSE
6 GTEx Adipose Visceral Omentum ZNF641 0.14 0.09 lasso 4 0.08 3.7e-05 -10.32 -9.3 1.9e-20 -0.38 0.66 0.05 FALSE
7 GTEx Adipose Visceral Omentum ASB8 0.10 0.00 lasso 6 0.00 6.8e-01 -8.97 -9.3 1.8e-20 -0.33 0.30 0.06 FALSE
8 GTEx Adipose Visceral Omentum RP1-228P16.1 0.18 0.13 lasso 4 0.15 2.3e-08 -8.73 11.5 1.7e-30 0.51 0.17 0.82 FALSE
9 GTEx Adrenal Gland ZNF641 0.31 0.18 lasso 3 0.21 4.2e-08 -10.61 -9.7 4.7e-22 -0.41 0.76 0.02 FALSE
10 GTEx Adrenal Gland RP1-228P16.1 0.19 0.20 lasso 5 0.15 4.4e-06 -8.47 8.3 1.5e-16 0.37 0.91 0.01 FALSE
11 GTEx Artery Aorta ZNF641 0.22 0.13 enet 30 0.18 4.9e-10 -10.59 -9.6 7.2e-22 -0.38 0.78 0.22 FALSE
12 GTEx Artery Aorta RP1-228P16.1 0.16 0.05 enet 28 0.11 1.7e-06 -10.59 9.6 5.4e-22 0.36 0.22 0.78 FALSE
13 GTEx Artery Coronary RP1-228P16.1 0.12 0.06 lasso 2 0.03 2.6e-02 -8.52 8.7 4.0e-18 0.37 0.31 0.40 FALSE
14 GTEx Artery Tibial ZNF641 0.19 0.16 lasso 5 0.16 1.6e-12 -10.32 -10.5 7.7e-26 -0.43 1.00 0.00 FALSE
15 GTEx Artery Tibial RP1-228P16.1 0.16 0.14 lasso 14 0.15 5.9e-12 -8.52 10.7 7.5e-27 0.51 1.00 0.00 FALSE
16 GTEx Brain Caudate basal ganglia ASB8 0.18 0.02 lasso 4 0.04 2.1e-02 -8.27 -6.9 3.7e-12 -0.35 0.12 0.11 FALSE
17 GTEx Brain Caudate basal ganglia RP1-228P16.1 0.14 0.12 lasso 4 0.11 5.7e-04 -8.73 9.3 1.8e-20 0.41 0.26 0.09 FALSE
18 GTEx Brain Cerebellar Hemisphere RP1-228P16.1 0.30 0.21 lasso 7 0.28 6.5e-08 -8.93 9.0 1.9e-19 0.41 0.94 0.02 FALSE
19 GTEx Brain Cerebellum RP1-228P16.1 0.16 0.05 enet 16 0.10 6.0e-04 -4.29 7.7 1.1e-14 0.25 0.33 0.09 FALSE
20 GTEx Brain Cortex TMEM106C 0.21 0.04 enet 20 0.10 1.0e-03 -8.93 -7.2 4.7e-13 -0.16 0.16 0.11 FALSE
21 GTEx Brain Cortex ASB8 0.28 0.19 lasso 7 0.20 3.3e-06 -8.27 -9.6 1.0e-21 -0.42 0.68 0.04 FALSE
22 GTEx Brain Frontal Cortex BA9 TMEM106C 0.35 0.01 lasso 8 -0.01 6.8e-01 12.93 -13.9 1.0e-43 -0.79 0.02 0.79 TRUE
23 GTEx Brain Frontal Cortex BA9 ASB8 0.24 0.16 lasso 6 0.07 7.1e-03 -8.27 -8.5 1.8e-17 -0.41 0.35 0.06 FALSE
24 GTEx Brain Hippocampus ZNF641 0.19 0.07 enet 10 0.04 3.3e-02 6.41 6.0 1.8e-09 0.41 0.07 0.28 FALSE
25 GTEx Brain Nucleus accumbens basal ganglia ASB8 0.20 0.04 lasso 4 0.02 7.7e-02 -9.37 -7.8 8.4e-15 -0.34 0.13 0.19 FALSE
26 GTEx Brain Putamen basal ganglia RP1-228P16.1 0.21 0.24 lasso 6 0.24 2.1e-06 -10.32 10.0 1.5e-23 0.40 0.48 0.14 FALSE
27 GTEx Breast Mammary Tissue ASB8 0.17 0.02 enet 12 0.02 1.9e-02 -11.66 -8.7 4.8e-18 -0.25 0.07 0.38 FALSE
28 GTEx Breast Mammary Tissue RP1-228P16.1 0.22 0.14 lasso 8 0.20 1.3e-10 -12.61 11.4 3.4e-30 0.49 0.09 0.90 FALSE
29 GTEx Breast Mammary Tissue (Male) RP1-228P16.1 0.13 0.00 lasso 6 0.01 1.8e-01 -12.38 11.7 1.8e-31 0.55 0.07 0.27 FALSE
30 GTEx Breast Mammary Tissue (Female) ZNF641 0.04 0.01 lasso 1 -0.01 6.0e-01 -12.36 -12.4 4.3e-35 -0.61 0.04 0.16 FALSE
31 GTEx Breast Mammary Tissue (Female) RP1-228P16.1 0.07 -0.01 enet 2 -0.01 5.9e-01 -8.93 11.2 2.7e-29 0.50 0.06 0.16 FALSE
32 GTEx Cells EBV-transformed lymphocytes RP1-228P16.1 0.33 0.20 lasso 9 0.29 6.3e-10 -9.38 10.8 2.9e-27 0.46 0.83 0.16 FALSE
33 GTEx Cells Transformed fibroblasts VDR 0.22 0.17 lasso 5 0.16 3.3e-12 -5.26 -5.3 1.2e-07 -0.28 1.00 0.00 FALSE
34 GTEx Cells Transformed fibroblasts ZNF641 0.10 0.05 lasso 4 0.05 7.5e-05 10.73 -9.4 5.4e-21 -0.81 0.25 0.72 FALSE
35 GTEx Cells Transformed fibroblasts RP1-228P16.1 0.09 0.03 lasso 3 0.04 8.1e-04 -9.38 11.0 2.6e-28 0.44 0.21 0.71 FALSE
36 GTEx Colon Sigmoid RP1-228P16.1 0.16 0.18 lasso 6 0.13 2.6e-05 -12.61 11.7 9.0e-32 0.54 0.09 0.84 FALSE
37 GTEx Colon Transverse RP1-228P16.1 0.24 0.18 lasso 5 0.18 4.9e-09 -8.73 10.6 2.5e-26 0.47 0.58 0.42 FALSE
38 GTEx Esophagus Gastroesophageal Junction RP1-228P16.1 0.23 0.25 enet 17 0.23 6.8e-09 -8.73 11.0 3.0e-28 0.53 0.43 0.56 FALSE
39 GTEx Esophagus Mucosa RP1-228P16.1 0.19 0.18 lasso 4 0.21 8.7e-14 -8.73 10.7 6.2e-27 0.50 0.89 0.11 FALSE
40 GTEx Esophagus Muscularis RP1-228P16.1 0.20 0.17 enet 14 0.17 1.2e-10 -8.73 8.4 3.1e-17 0.34 0.99 0.01 FALSE
41 GTEx Heart Atrial Appendage RP1-228P16.1 0.16 0.02 enet 14 0.02 3.2e-02 -12.38 12.2 1.9e-34 0.55 0.14 0.56 FALSE
42 GTEx Heart Left Ventricle RP1-228P16.1 0.26 0.14 lasso 16 0.17 1.9e-09 -8.73 9.6 5.0e-22 0.40 0.99 0.01 FALSE
43 GTEx Liver RP1-228P16.1 0.19 0.08 lasso 7 0.06 7.1e-03 -11.66 12.8 1.4e-37 0.64 0.16 0.33 FALSE
44 GTEx Lung ZNF641 0.08 0.10 lasso 2 0.08 8.0e-07 -10.50 -10.5 8.5e-26 -0.42 1.00 0.00 FALSE
45 GTEx Lung RP1-228P16.1 0.18 0.20 enet 21 0.21 7.0e-16 -9.37 9.8 1.6e-22 0.43 1.00 0.00 FALSE
46 GTEx Muscle Skeletal RP1-228P16.1 0.12 0.10 lasso 9 0.09 7.4e-09 -8.73 10.3 5.5e-25 0.52 0.96 0.04 FALSE
47 GTEx Nerve Tibial ZNF641 0.14 0.11 lasso 4 0.08 2.3e-06 -10.32 -10.6 2.7e-26 -0.43 1.00 0.00 FALSE
48 GTEx Nerve Tibial ASB8 0.09 0.08 lasso 4 0.07 1.8e-05 -8.52 -8.5 1.4e-17 -0.39 0.82 0.01 FALSE
49 GTEx Nerve Tibial RP1-228P16.1 0.18 0.21 enet 22 0.21 4.9e-15 -8.93 10.4 3.8e-25 0.47 0.99 0.01 FALSE
50 GTEx Ovary C12orf68 0.38 0.08 enet 29 0.05 1.9e-02 -6.59 -6.9 5.9e-12 -0.30 0.07 0.07 FALSE
51 GTEx Pancreas RP1-228P16.1 0.12 0.05 enet 10 0.05 5.0e-03 -4.31 8.3 9.0e-17 0.31 0.37 0.15 FALSE
52 GTEx Pituitary RP1-228P16.1 0.20 0.15 lasso 6 0.16 1.1e-04 -8.73 11.3 1.4e-29 0.48 0.30 0.29 FALSE
53 GTEx Skin Not Sun Exposed Suprapubic ZNF641 0.15 0.11 enet 30 0.10 3.1e-06 -10.32 -11.9 1.5e-32 -0.55 0.64 0.35 FALSE
54 GTEx Skin Not Sun Exposed Suprapubic RP1-228P16.1 0.17 0.10 enet 23 0.16 4.1e-09 -10.47 8.1 6.3e-16 0.20 0.95 0.03 FALSE
55 GTEx Skin Sun Exposed Lower leg PFKM 0.22 0.16 enet 34 0.17 5.0e-14 -6.91 -8.0 1.2e-15 -0.33 1.00 0.00 TRUE
56 GTEx Skin Sun Exposed Lower leg ZNF641 0.21 0.03 enet 17 0.08 6.5e-07 4.74 -10.4 3.4e-25 -0.60 0.24 0.75 TRUE
57 GTEx Skin Sun Exposed Lower leg RP1-228P16.1 0.29 0.24 enet 28 0.26 2.0e-21 -8.50 6.8 1.2e-11 0.26 1.00 0.00 FALSE
58 GTEx Spleen ZNF641 0.42 0.21 lasso 11 0.28 5.4e-08 -0.35 -6.8 1.3e-11 -0.20 0.70 0.02 FALSE
59 GTEx Spleen C12orf68 0.24 0.01 lasso 4 0.03 6.8e-02 -6.88 -6.2 4.4e-10 -0.32 0.12 0.16 FALSE
60 GTEx Spleen RP1-228P16.1 0.35 0.23 lasso 7 0.19 1.6e-05 -8.93 9.3 1.5e-20 0.41 0.62 0.24 FALSE
61 GTEx Stomach RP1-228P16.1 0.12 0.03 lasso 7 0.05 1.9e-03 -8.73 8.3 1.2e-16 0.34 0.77 0.06 FALSE
62 GTEx Testis SENP1 0.20 0.13 lasso 5 0.10 2.7e-05 -12.70 -12.9 3.7e-38 -0.57 0.04 0.95 TRUE
63 GTEx Testis ASB8 0.17 0.15 lasso 3 0.13 1.8e-06 -9.14 -10.8 3.1e-27 -0.46 0.22 0.68 FALSE
64 GTEx Testis RP1-228P16.1 0.38 0.28 lasso 6 0.31 4.0e-14 -8.93 7.7 1.5e-14 0.37 1.00 0.00 FALSE
65 GTEx Thyroid ZNF641 0.16 0.06 enet 26 0.13 2.0e-10 -1.01 -7.0 3.5e-12 -0.19 1.00 0.00 FALSE
66 GTEx Thyroid ADCY6 0.11 0.01 enet 29 0.03 3.1e-03 -2.14 -5.9 4.6e-09 -0.01 0.07 0.04 FALSE
67 GTEx Thyroid ASB8 0.09 0.00 enet 34 0.01 2.8e-02 -8.54 -6.8 9.2e-12 -0.16 0.65 0.04 FALSE
68 GTEx Thyroid RP1-228P16.1 0.30 0.30 enet 41 0.33 1.4e-25 -8.50 8.1 7.3e-16 0.33 1.00 0.00 FALSE
69 GTEx Thyroid RP11-579D7.2 0.14 0.02 enet 31 0.02 7.3e-03 1.83 -5.8 8.1e-09 -0.13 0.14 0.04 FALSE
70 GTEx Uterus RP1-228P16.1 0.32 0.09 lasso 15 0.01 2.1e-01 -9.37 8.3 7.9e-17 0.39 0.11 0.22 FALSE
71 GTEx Whole Blood RP1-228P16.1 0.10 0.06 enet 20 0.09 4.7e-09 -8.97 10.0 1.1e-23 0.42 0.73 0.26 FALSE
72 METSIM Adipose ASB8 0.03 0.00 bslmm 526 0.01 3.8e-02 -8.93 -9.2 2.7e-20 -0.46 0.18 0.06 FALSE
73 METSIM Adipose DKFZP779L1853 0.03 0.02 lasso 5 0.03 9.8e-06 -0.93 5.9 3.0e-09 0.45 0.62 0.23 FALSE
74 METSIM Adipose PFKM 0.05 0.01 bslmm 525 0.02 7.3e-04 -6.40 6.0 1.6e-09 0.34 0.48 0.02 FALSE
75 NTR Blood RPAP3 0.02 0.00 bslmm 575 0.00 2.3e-02 -2.05 8.5 2.5e-17 0.16 0.07 0.30 FALSE
76 NTR Blood VDR 0.05 0.02 enet 24 0.02 1.5e-08 5.39 5.2 2.0e-07 0.26 0.99 0.00 FALSE
77 YFS Blood PFKM 0.03 0.00 blup 523 0.01 2.5e-05 4.35 -9.1 1.2e-19 -0.15 0.18 0.04 FALSE
78 The Cancer Genome Atlas Bladder Urothelial Carcinoma SENP1 0.10 0.05 blup 87 0.04 2.2e-04 8.42 6.8 1.3e-11 0.48 0.39 0.09 FALSE
79 The Cancer Genome Atlas Breast Invasive Carcinoma SENP1 0.01 0.00 blup 87 0.01 1.8e-02 11.68 11.4 3.5e-30 0.65 0.04 0.30 FALSE
80 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma ZNF641 0.09 0.01 blup 50 0.03 8.7e-03 -1.43 7.1 1.0e-12 0.72 0.02 0.80 TRUE
81 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SENP1 0.07 0.01 blup 87 0.02 1.9e-03 8.42 6.3 3.7e-10 0.55 0.11 0.04 FALSE
82 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ASB8 0.04 0.03 blup 69 0.03 4.1e-04 -10.47 -6.1 1.0e-09 -0.25 0.05 0.83 FALSE
83 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ZNF641 0.09 0.01 blup 50 0.06 7.1e-07 6.82 -7.3 3.0e-13 -0.09 0.15 0.03 FALSE
84 The Cancer Genome Atlas Brain Lower Grade Glioma ASB8 0.08 0.01 blup 69 0.04 3.9e-05 -8.27 -6.4 1.9e-10 -0.20 0.41 0.26 FALSE
85 The Cancer Genome Atlas Brain Lower Grade Glioma H1FNT 0.08 0.08 enet 3 0.07 1.5e-08 12.93 -12.4 3.3e-35 -0.99 0.00 1.00 FALSE
86 The Cancer Genome Atlas Brain Lower Grade Glioma SENP1 0.04 0.01 enet 8 0.02 1.4e-03 9.82 8.5 2.0e-17 0.55 0.06 0.12 FALSE
87 The Cancer Genome Atlas Lung Adenocarcinoma SENP1 0.06 0.03 lasso 3 0.04 4.6e-05 9.82 9.5 3.0e-21 0.59 0.31 0.20 FALSE
88 The Cancer Genome Atlas Lung Adenocarcinoma TMEM106C 0.04 0.01 blup 76 0.02 1.3e-03 8.42 6.4 1.2e-10 0.41 0.02 0.47 FALSE
89 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SENP1 0.04 0.03 blup 87 0.03 4.4e-04 -12.61 12.0 4.8e-33 0.58 0.00 0.99 FALSE
90 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma ASB8 0.07 0.05 lasso 1 0.04 1.0e-03 10.71 10.7 9.3e-27 0.80 0.00 0.90 FALSE
91 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma PFKM 0.10 0.02 lasso 1 0.03 7.5e-03 9.82 9.8 9.2e-23 0.61 0.08 0.75 FALSE
92 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma SENP1 0.09 0.02 enet 10 0.06 1.1e-04 11.68 11.2 2.9e-29 0.62 0.02 0.89 TRUE
93 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TMEM106C 0.09 0.00 blup 76 0.04 1.5e-03 11.68 10.0 2.3e-23 0.62 0.01 0.51 TRUE
94 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma ZNF641 0.05 0.04 blup 50 0.02 1.2e-02 12.93 12.3 1.2e-34 0.95 0.00 0.89 FALSE
95 The Cancer Genome Atlas Prostate Adenocarcinoma SENP1 0.06 0.00 blup 87 0.01 5.7e-02 0.31 7.4 1.3e-13 0.62 0.05 0.08 FALSE
96 The Cancer Genome Atlas Stomach Adenocarcinoma ASB8 0.09 0.01 blup 69 0.04 1.1e-03 9.91 6.9 5.0e-12 0.38 0.02 0.75 FALSE
97 The Cancer Genome Atlas Stomach Adenocarcinoma SENP1 0.09 0.03 lasso 4 0.03 4.8e-03 8.64 6.6 3.3e-11 0.47 0.40 0.06 FALSE
98 The Cancer Genome Atlas Thyroid Carcinoma ASB8 0.04 0.03 lasso 3 0.03 2.3e-04 -8.27 -7.9 2.7e-15 -0.39 0.52 0.12 FALSE
99 The Cancer Genome Atlas Thyroid Carcinoma OR10AD1 0.06 0.03 lasso 3 0.05 7.6e-06 -0.62 -5.5 4.0e-08 -0.08 0.12 0.63 FALSE
100 The Cancer Genome Atlas Thyroid Carcinoma SENP1 0.04 0.01 lasso 3 0.00 1.3e-01 8.42 8.4 3.8e-17 0.53 0.02 0.21 FALSE
101 The Cancer Genome Atlas Thyroid Carcinoma VDR 0.06 0.03 enet 18 0.03 3.1e-04 5.09 6.5 7.5e-11 0.26 0.16 0.06 FALSE
102 The Cancer Genome Atlas Thyroid Carcinoma ZNF641 0.11 0.12 enet 10 0.12 5.2e-12 -10.61 -7.1 1.0e-12 -0.14 1.00 0.00 FALSE