TWAS
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Usage
Models
Genes
Traits
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Traits
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Blood Red Count
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chr15:85,227,407-86,990,983
Best TWAS P=1.27e-09 · Best GWAS P=7.47e-13 conditioned to 5.32e-08
85.2M
85.4M
85.6M
85.8M
86M
86.2M
86.4M
86.6M
86.8M
87M
0
2
4
6
8
10
12
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Testis
RP11-158M2.3
0.20
0.22
lasso
5
0.20
2.1e-09
6.0
-6.1
1.3e-09
0.34
0.79
0.21
TRUE
3
The Cancer Genome Atlas
Prostate Adenocarcinoma
AKAP13
0.08
0.03
enet
11
0.08
2.3e-08
4.6
5.3
1.4e-07
-0.30
0.97
0.01
FALSE
2
YFS
Blood
AKAP13
0.14
0.09
lasso
19
0.15
2.6e-46
-3.5
-5.2
1.7e-07
0.71
1.00
0.00
FALSE