Best TWAS P=1.27e-09 · Best GWAS P=7.47e-13 conditioned to 5.32e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | RP11-158M2.3 | 0.20 | 0.22 | lasso | 5 | 0.20 | 2.1e-09 | 6.0 | -6.1 | 1.3e-09 | 0.34 | 0.79 | 0.21 | TRUE |
| 2 | YFS | Blood | AKAP13 | 0.14 | 0.09 | lasso | 19 | 0.15 | 2.6e-46 | -3.5 | -5.2 | 1.7e-07 | 0.71 | 1.00 | 0.00 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | AKAP13 | 0.08 | 0.03 | enet | 11 | 0.08 | 2.3e-08 | 4.6 | 5.3 | 1.4e-07 | -0.30 | 0.97 | 0.01 | FALSE |