TWAS
hub
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Usage
Models
Genes
Traits
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Traits
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Blood Red Count
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chr20:39,270,768-40,683,594
Best TWAS P=2.69e-09 · Best GWAS P=1.73e-09 conditioned to 1
39.2M
39.4M
39.6M
39.8M
40M
40.2M
40.4M
40.6M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
5
The Cancer Genome Atlas
Prostate Adenocarcinoma
ZHX3
0.05
0.06
lasso
2
0.05
2.6e-06
5.9
-6.0
2.7e-09
-0.99
0.01
0.99
TRUE
4
The Cancer Genome Atlas
Brain Lower Grade Glioma
LPIN3
0.03
0.04
lasso
2
0.03
5.5e-04
5.2
5.3
1.1e-07
0.67
0.05
0.78
FALSE
3
ROSMAP
Brain Pre-frontal Cortex
LPIN3
0.11
0.10
lasso
8
0.12
2.5e-15
5.2
5.3
1.4e-07
0.61
0.53
0.47
FALSE
2
GTEx
Artery Tibial
LPIN3
0.17
0.13
lasso
6
0.15
6.5e-12
5.2
5.3
1.5e-07
0.70
0.68
0.32
FALSE
1
GTEx
Artery Aorta
LPIN3
0.08
0.08
enet
4
0.08
5.4e-05
5.2
5.2
2.0e-07
0.62
0.26
0.66
FALSE