Best TWAS P=2.69e-09 · Best GWAS P=1.73e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | LPIN3 | 0.08 | 0.08 | enet | 4 | 0.08 | 5.4e-05 | 5.2 | 5.2 | 2.0e-07 | 0.62 | 0.26 | 0.66 | FALSE |
| 2 | GTEx | Artery Tibial | LPIN3 | 0.17 | 0.13 | lasso | 6 | 0.15 | 6.5e-12 | 5.2 | 5.3 | 1.5e-07 | 0.70 | 0.68 | 0.32 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | LPIN3 | 0.11 | 0.10 | lasso | 8 | 0.12 | 2.5e-15 | 5.2 | 5.3 | 1.4e-07 | 0.61 | 0.53 | 0.47 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | LPIN3 | 0.03 | 0.04 | lasso | 2 | 0.03 | 5.5e-04 | 5.2 | 5.3 | 1.1e-07 | 0.67 | 0.05 | 0.78 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ZHX3 | 0.05 | 0.06 | lasso | 2 | 0.05 | 2.6e-06 | 5.9 | -6.0 | 2.7e-09 | -0.99 | 0.01 | 0.99 | TRUE |