[Hub]/) : Traits : Blood Red Count :

chr20:24,485,525-34,484,245

Best TWAS P=6.74e-32 · Best GWAS P=2.36e-22 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C20orf203 0.12 0.08 bslmm 414 0.06 2.5e-08 -8.77 -5.7 1.3e-08 -0.08 0.88 0.12 FALSE
2 CommonMind Brain Pre-frontal Cortex E2F1 0.06 0.01 bslmm 268 0.02 1.6e-03 4.38 -5.5 3.7e-08 -0.01 0.02 0.87 TRUE
3 CommonMind Brain Pre-frontal Cortex FRG1B 0.15 0.11 lasso 5 0.11 1.4e-13 -6.11 -6.0 2.4e-09 0.29 1.00 0.00 FALSE
4 CommonMind Brain Pre-frontal Cortex MAP1LC3A 0.22 0.14 blup 309 0.19 3.9e-22 -5.44 5.2 1.5e-07 0.00 0.12 0.88 FALSE
5 GTEx Adipose Subcutaneous COX4I2 0.09 0.11 lasso 3 0.11 5.3e-09 -8.82 -9.3 2.0e-20 0.87 0.07 0.93 FALSE
6 GTEx Adipose Subcutaneous FRG1B 0.06 0.04 enet 8 0.04 3.6e-04 -4.94 -6.0 2.0e-09 0.33 0.61 0.10 TRUE
7 GTEx Adipose Subcutaneous NCOA6 0.10 0.06 enet 29 0.07 1.3e-06 -4.41 7.0 2.8e-12 -0.03 0.46 0.53 TRUE
8 GTEx Artery Aorta PYGB 0.07 0.02 lasso 9 0.02 3.4e-02 -7.27 -5.8 5.7e-09 0.15 0.08 0.63 TRUE
9 GTEx Artery Tibial PYGB 0.13 0.01 enet 21 0.08 4.2e-07 -7.27 -7.6 2.5e-14 -0.02 0.04 0.87 FALSE
10 GTEx Artery Tibial PIGU 0.05 0.05 lasso 3 0.04 2.2e-04 -5.44 5.5 3.1e-08 0.00 0.07 0.91 FALSE
11 GTEx Artery Tibial BAK1P1 0.08 0.03 lasso 2 0.06 1.4e-05 7.28 7.2 6.2e-13 0.00 0.24 0.07 FALSE
12 GTEx Brain Caudate basal ganglia COX4I2 0.24 0.03 lasso 6 0.05 1.1e-02 -8.90 -8.3 6.8e-17 0.54 0.13 0.53 FALSE
13 GTEx Brain Cerebellum PROCR 0.29 0.01 enet 34 0.13 1.1e-04 -2.25 5.5 3.6e-08 -0.04 0.04 0.07 FALSE
14 GTEx Brain Cerebellum CTD-2514C3.1 0.21 0.05 lasso 5 0.15 3.5e-05 -7.39 8.1 5.7e-16 -0.16 0.05 0.79 TRUE
15 GTEx Brain Cortex GSS 0.14 0.02 lasso 3 0.00 3.7e-01 -5.44 5.4 5.6e-08 0.00 0.06 0.56 FALSE
16 GTEx Brain Frontal Cortex BA9 MAP1LC3A 0.18 0.17 lasso 4 0.16 5.3e-05 -5.04 5.4 5.9e-08 0.02 0.12 0.78 FALSE
17 GTEx Brain Frontal Cortex BA9 NCOA6 0.13 0.00 enet 30 0.06 1.3e-02 -3.75 5.6 1.9e-08 -0.03 0.08 0.57 FALSE
18 GTEx Brain Nucleus accumbens basal ganglia COX4I2 0.13 0.14 lasso 5 0.05 2.2e-02 -9.59 -10.2 1.9e-24 0.96 0.04 0.70 FALSE
19 GTEx Breast Mammary Tissue NCOA6 0.12 0.02 enet 35 0.04 4.5e-03 -5.00 5.8 8.4e-09 -0.02 0.12 0.70 FALSE
20 GTEx Breast Mammary Tissue VN1R108P 0.11 0.03 enet 16 0.05 1.7e-03 -6.89 -7.3 2.3e-13 0.14 0.06 0.86 FALSE
21 GTEx Breast Mammary Tissue (Male) MAP1LC3A 0.13 0.05 enet 12 0.00 3.4e-01 -5.58 5.3 1.2e-07 0.01 0.06 0.24 FALSE
22 GTEx Breast Mammary Tissue (Male) ZNF337 0.39 0.03 enet 16 0.13 6.3e-04 0.67 5.3 1.2e-07 -0.05 0.08 0.20 FALSE
23 GTEx Breast Mammary Tissue (Female) VN1R108P 0.15 0.11 lasso 6 0.09 1.5e-03 -7.51 -7.7 1.0e-14 0.13 0.08 0.51 FALSE
24 GTEx Cells EBV-transformed lymphocytes CTD-2514C3.1 0.17 0.03 enet 9 0.08 1.1e-03 -7.87 5.9 2.8e-09 -0.09 0.03 0.58 FALSE
25 GTEx Cells Transformed fibroblasts GINS1 0.04 0.01 lasso 3 0.01 5.2e-02 -7.51 -5.3 9.2e-08 0.17 0.07 0.89 FALSE
26 GTEx Cells Transformed fibroblasts HM13 0.07 0.05 lasso 4 0.06 3.9e-05 -8.58 -8.6 7.0e-18 0.68 0.71 0.21 FALSE
27 GTEx Cells Transformed fibroblasts FRG1B 0.05 0.04 lasso 3 0.03 2.2e-03 -4.89 -5.6 1.8e-08 0.47 0.14 0.48 FALSE
28 GTEx Cells Transformed fibroblasts CTD-2514C3.1 0.06 0.03 lasso 3 0.01 6.9e-02 -6.34 6.3 2.1e-10 -0.07 0.05 0.13 TRUE
29 GTEx Cells Transformed fibroblasts HM13-AS1 0.04 0.01 lasso 3 0.01 1.0e-01 -8.57 9.1 7.6e-20 -0.75 0.13 0.44 FALSE
30 GTEx Colon Sigmoid ENTPD6 0.17 0.12 enet 12 0.14 1.1e-05 4.27 -5.2 1.9e-07 0.04 0.51 0.08 FALSE
31 GTEx Colon Transverse MYH7B 0.14 0.01 enet 20 0.01 8.4e-02 1.81 5.4 7.8e-08 -0.02 0.12 0.50 FALSE
32 GTEx Colon Transverse DUSP15 0.33 0.06 lasso 6 0.14 2.2e-07 -7.04 7.6 4.0e-14 -0.54 0.23 0.46 FALSE
33 GTEx Esophagus Mucosa PYGB 0.12 0.01 enet 19 0.02 9.7e-03 -6.89 -5.4 5.4e-08 0.01 0.02 0.85 FALSE
34 GTEx Esophagus Mucosa HM13 0.06 0.01 lasso 5 0.00 2.7e-01 -7.43 -7.3 3.5e-13 0.82 0.04 0.67 FALSE
35 GTEx Esophagus Mucosa NCOA6 0.10 0.06 lasso 16 0.09 8.0e-07 -4.33 5.3 1.3e-07 -0.01 0.83 0.14 FALSE
36 GTEx Esophagus Mucosa RP4-614O4.12 0.12 0.07 enet 16 0.06 6.7e-05 -4.07 -5.2 2.3e-07 0.00 0.10 0.77 FALSE
37 GTEx Esophagus Muscularis PYGB 0.22 0.19 enet 13 0.21 1.1e-12 -7.27 -6.9 6.3e-12 0.10 0.02 0.98 FALSE
38 GTEx Esophagus Muscularis COX4I2 0.09 0.12 enet 10 0.09 4.1e-06 -8.81 -9.3 2.1e-20 0.92 0.03 0.97 FALSE
39 GTEx Esophagus Muscularis CTD-2514C3.1 0.16 0.07 lasso 7 0.10 6.3e-07 -6.34 7.2 6.8e-13 -0.11 0.18 0.80 FALSE
40 GTEx Heart Atrial Appendage FRG1B 0.07 0.02 enet 10 0.01 1.7e-01 -4.89 -5.2 1.8e-07 0.26 0.18 0.14 FALSE
41 GTEx Heart Left Ventricle COX4I2 0.06 0.05 lasso 6 0.01 6.2e-02 -7.36 -8.9 6.0e-19 0.94 0.03 0.95 FALSE
42 GTEx Heart Left Ventricle NCOA6 0.09 0.01 enet 19 0.05 1.1e-03 -3.73 5.8 5.9e-09 -0.03 0.37 0.32 TRUE
43 GTEx Lung COX4I2 0.05 0.01 enet 6 0.03 1.8e-03 -8.82 -10.1 6.1e-24 0.89 0.08 0.78 FALSE
44 GTEx Lung FRG1B 0.08 0.04 enet 15 0.05 7.9e-05 -4.94 -5.8 6.9e-09 0.34 0.94 0.03 FALSE
45 GTEx Lung CTD-2514C3.1 0.05 0.03 lasso 3 0.04 2.8e-04 -6.34 6.7 2.8e-11 -0.08 0.30 0.42 FALSE
46 GTEx Muscle Skeletal HM13 0.05 0.01 enet 15 0.05 2.1e-05 -4.51 8.4 2.8e-17 -0.71 0.03 0.93 FALSE
47 GTEx Muscle Skeletal COX4I2 0.10 0.08 lasso 4 0.09 3.5e-09 -8.81 -9.4 7.2e-21 0.93 0.04 0.96 FALSE
48 GTEx Muscle Skeletal FRG1B 0.06 0.09 enet 12 0.08 1.2e-08 -4.98 -6.2 7.0e-10 0.31 1.00 0.00 FALSE
49 GTEx Nerve Tibial COX4I2 0.13 0.10 lasso 9 0.07 6.6e-06 -8.81 -8.3 1.2e-16 0.84 0.04 0.96 FALSE
50 GTEx Nerve Tibial NCOA6 0.24 0.12 enet 50 0.20 5.2e-14 3.36 5.4 5.6e-08 -0.02 0.95 0.04 TRUE
51 GTEx Nerve Tibial CTD-2514C3.1 0.11 0.09 lasso 4 0.07 1.8e-05 -6.34 5.5 2.9e-08 -0.06 0.72 0.03 FALSE
52 GTEx Skin Not Sun Exposed Suprapubic COX4I2 0.08 0.05 lasso 4 0.05 1.5e-03 -9.59 -9.3 1.4e-20 0.94 0.03 0.96 FALSE
53 GTEx Skin Not Sun Exposed Suprapubic ENTPD6 0.12 0.09 lasso 2 0.07 1.1e-04 5.66 -5.7 1.5e-08 -0.07 0.30 0.08 FALSE
54 GTEx Skin Sun Exposed Lower leg TPX2 0.05 0.00 lasso 3 0.00 5.5e-01 -6.17 -7.8 4.7e-15 0.81 0.11 0.54 FALSE
55 GTEx Skin Sun Exposed Lower leg PYGB 0.11 0.10 lasso 4 0.09 1.2e-07 5.37 -5.3 9.1e-08 -0.07 0.99 0.00 FALSE
56 GTEx Skin Sun Exposed Lower leg COX4I2 0.03 0.04 enet 6 0.04 3.6e-04 -8.82 -8.8 1.7e-18 0.85 0.16 0.77 FALSE
57 GTEx Skin Sun Exposed Lower leg FRG1B 0.03 0.00 enet 7 0.01 9.4e-02 -4.89 -6.4 1.3e-10 0.43 0.04 0.35 FALSE
58 GTEx Skin Sun Exposed Lower leg ENTPD6 0.11 0.07 lasso 9 0.06 1.6e-05 5.37 -5.8 7.4e-09 -0.04 0.94 0.00 FALSE
59 GTEx Skin Sun Exposed Lower leg HM13-AS1 0.07 0.07 enet 11 0.05 5.3e-05 -9.68 10.2 1.6e-24 -0.83 0.02 0.98 FALSE
60 GTEx Small Intestine Terminal Ileum RSL24D1P6 0.18 -0.01 enet 17 0.00 3.2e-01 3.62 7.0 2.2e-12 -0.02 0.11 0.09 FALSE
61 GTEx Stomach FRG1B 0.05 0.07 lasso 2 0.04 6.5e-03 -6.15 -6.4 1.2e-10 0.58 0.03 0.55 TRUE
62 GTEx Testis PIGU 0.38 0.48 lasso 6 0.47 1.9e-23 -5.44 5.6 2.3e-08 0.00 0.06 0.94 FALSE
63 GTEx Testis DUSP15 0.10 0.01 lasso 8 0.00 3.1e-01 -3.29 -6.0 1.4e-09 0.53 0.07 0.14 FALSE
64 GTEx Thyroid PYGB 0.10 0.09 lasso 2 0.09 4.4e-07 5.66 -5.5 4.4e-08 -0.07 0.98 0.00 FALSE
65 GTEx Thyroid COX4I2 0.04 0.05 lasso 2 0.03 1.8e-03 -8.82 -8.7 2.6e-18 0.87 0.08 0.83 FALSE
66 GTEx Vagina PXMP4 0.29 0.11 lasso 4 0.17 1.0e-04 4.84 -5.2 2.1e-07 0.02 0.04 0.20 FALSE
67 GTEx Vagina COX4I2 0.17 0.12 lasso 2 0.16 1.5e-04 -8.81 -8.2 2.5e-16 0.75 0.03 0.88 FALSE
68 GTEx Vagina RSL24D1P6 0.44 -0.01 lasso 13 0.00 2.5e-01 -7.49 7.9 2.1e-15 -0.11 0.06 0.09 FALSE
69 GTEx Whole Blood HM13 0.05 0.05 lasso 4 0.05 1.4e-05 -8.62 -8.0 9.7e-16 0.67 0.83 0.16 FALSE
70 GTEx Whole Blood RP5-1085F17.3 0.16 0.01 enet 29 0.07 8.2e-07 -2.03 6.4 1.8e-10 -0.04 0.53 0.32 FALSE
71 METSIM Adipose COMMD7 0.04 0.02 bslmm 419 0.02 1.7e-03 1.52 5.3 1.1e-07 0.05 0.12 0.60 TRUE
72 NTR Blood C20orf160 0.01 0.00 bslmm 305 0.00 8.0e-03 -8.82 11.8 6.7e-32 -0.74 0.03 0.61 TRUE
73 NTR Blood HM13 0.03 0.05 lasso 6 0.05 2.2e-15 -8.64 -8.8 9.9e-19 0.70 1.00 0.00 FALSE
74 ROSMAP Brain Pre-frontal Cortex HM13 0.08 0.14 lasso 4 0.15 3.7e-19 -8.44 9.0 2.5e-19 -0.82 0.91 0.09 FALSE
75 ROSMAP Brain Pre-frontal Cortex COX4I2 0.12 0.04 enet 18 0.07 7.8e-10 -6.56 -5.3 1.3e-07 0.64 0.83 0.17 FALSE
76 ROSMAP Brain Pre-frontal Cortex ACSS2 0.07 0.06 blup 353 0.07 9.4e-10 -4.33 5.4 5.3e-08 -0.01 0.19 0.80 FALSE
77 ROSMAP Brain Pre-frontal Cortex FRG1B 0.06 0.09 lasso 4 0.09 4.2e-11 -4.65 -5.5 5.0e-08 0.30 1.00 0.00 TRUE
78 ROSMAP Brain Pre-frontal Cortex BAK1P1 0.30 0.20 lasso 6 0.22 5.7e-28 -8.87 9.0 2.1e-19 0.05 0.82 0.18 FALSE
79 ROSMAP Brain Pre-frontal Cortex C20orf203 0.35 0.25 enet 14 0.27 1.8e-34 -8.78 -9.3 8.8e-21 -0.07 0.90 0.10 FALSE
80 ROSMAP Brain Pre-frontal Cortex NCOA6 0.07 0.08 blup 365 0.09 1.9e-11 -3.73 5.2 2.1e-07 -0.02 0.88 0.11 FALSE
81 ROSMAP Brain Pre-frontal Cortex RP4-610C12.4 0.13 0.17 lasso 7 0.20 2.4e-25 -6.11 -5.3 1.2e-07 0.20 0.98 0.02 FALSE
82 ROSMAP Brain Pre-frontal Cortex VN1R108P 0.05 0.01 blup 217 0.02 2.1e-03 -6.34 -7.8 6.0e-15 0.09 0.06 0.21 FALSE
83 YFS Blood ASXL1 0.03 0.02 blup 366 0.02 6.0e-08 3.88 6.8 1.4e-11 -0.05 0.78 0.22 FALSE
84 YFS Blood HM13 0.08 0.10 lasso 6 0.10 3.6e-31 -7.84 -8.4 4.6e-17 0.72 0.99 0.01 FALSE
85 YFS Blood NCOA6 0.03 0.03 blup 368 0.03 6.9e-10 -3.72 5.3 1.0e-07 -0.01 0.93 0.06 FALSE
86 The Cancer Genome Atlas Breast Invasive Carcinoma C20orf203 0.02 0.01 enet 4 0.02 1.6e-04 -8.78 -8.6 1.1e-17 -0.01 0.18 0.07 FALSE
87 The Cancer Genome Atlas Breast Invasive Carcinoma COX4I2 0.08 0.06 enet 7 0.06 3.3e-13 -6.56 -6.5 5.9e-11 0.65 1.00 0.00 FALSE
88 The Cancer Genome Atlas Colon Adenocarcinoma PYGB 0.09 0.07 lasso 3 0.06 3.4e-04 5.37 -5.4 6.4e-08 -0.07 0.16 0.03 FALSE
89 The Cancer Genome Atlas Esophageal Carcinoma MAP1LC3A 0.62 0.01 enet 24 0.13 5.9e-05 4.65 6.0 2.5e-09 0.03 0.01 0.34 FALSE
90 The Cancer Genome Atlas Glioblastoma Multiforme ID1 0.12 0.01 enet 4 0.05 1.3e-02 -7.84 7.5 4.4e-14 -0.64 0.01 0.34 FALSE
91 The Cancer Genome Atlas Glioblastoma Multiforme MYLK2 0.30 0.10 blup 43 0.16 1.3e-05 -9.26 7.3 4.0e-13 -0.69 0.01 0.86 FALSE
92 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma HM13 0.06 0.03 blup 48 0.07 3.0e-08 -8.59 -8.2 2.3e-16 0.70 0.04 0.96 FALSE
93 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PYGB 0.06 0.03 blup 74 0.02 9.8e-04 5.66 -5.2 1.5e-07 -0.01 0.18 0.03 FALSE
94 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma COX4I2 0.06 0.03 lasso 3 0.03 1.5e-04 -6.56 -8.4 5.7e-17 0.86 0.03 0.93 FALSE
95 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DUSP15 0.05 0.01 blup 44 0.01 7.7e-03 -9.65 7.3 3.8e-13 -0.66 0.01 0.84 FALSE
96 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LOC100134868 0.02 0.01 blup 11 0.01 2.1e-02 -3.91 5.7 1.4e-08 -0.07 0.01 0.30 FALSE
97 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PYGB 0.14 0.04 enet 12 0.07 5.1e-08 4.74 -6.0 2.4e-09 -0.06 0.61 0.36 FALSE
98 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PYGB 0.31 0.16 lasso 3 0.15 3.8e-09 5.37 -5.2 2.2e-07 -0.06 0.99 0.00 FALSE
99 The Cancer Genome Atlas Brain Lower Grade Glioma BCL2L1 0.05 0.03 enet 8 0.02 9.4e-04 -7.47 -5.9 3.0e-09 0.58 0.10 0.19 FALSE
100 The Cancer Genome Atlas Brain Lower Grade Glioma C20orf203 0.06 0.06 blup 48 0.05 1.6e-06 7.20 -10.5 1.1e-25 -0.03 0.87 0.03 TRUE
101 The Cancer Genome Atlas Brain Lower Grade Glioma MYLK2 0.06 0.02 blup 43 0.04 8.0e-06 -9.65 8.6 1.0e-17 -0.76 0.01 0.99 FALSE
102 The Cancer Genome Atlas Brain Lower Grade Glioma PIGU 0.03 0.02 blup 73 0.02 3.7e-03 -5.11 5.6 1.8e-08 0.01 0.01 0.91 FALSE
103 The Cancer Genome Atlas Lung Adenocarcinoma COX4I2 0.04 0.06 enet 6 0.05 9.8e-07 -8.90 -9.1 1.3e-19 0.75 0.40 0.59 FALSE
104 The Cancer Genome Atlas Lung Squamous Cell Carcinoma COX4I2 0.04 0.03 blup 25 0.04 2.5e-05 -7.36 -8.8 9.6e-19 0.89 0.01 0.99 FALSE
105 The Cancer Genome Atlas Lung Squamous Cell Carcinoma HM13 0.05 0.01 blup 48 0.02 8.1e-04 -8.90 -8.7 3.8e-18 0.65 0.01 0.98 FALSE
106 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma ITCH 0.14 0.04 lasso 4 0.03 3.8e-03 -6.18 -5.7 1.5e-08 -0.01 0.00 0.79 FALSE
107 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma LOC100134868 0.07 0.02 blup 11 0.03 2.1e-02 -3.91 6.0 1.9e-09 -0.16 0.00 0.45 FALSE
108 The Cancer Genome Atlas Prostate Adenocarcinoma C20orf203 0.04 0.03 blup 48 0.02 3.7e-03 -6.61 -7.9 2.0e-15 -0.10 0.04 0.08 FALSE
109 The Cancer Genome Atlas Prostate Adenocarcinoma COX4I2 0.07 0.07 lasso 5 0.07 2.0e-07 -8.82 -8.8 1.2e-18 0.86 0.20 0.80 FALSE
110 The Cancer Genome Atlas Prostate Adenocarcinoma ENTPD6 0.14 0.00 enet 19 0.03 4.5e-04 5.37 -6.9 5.3e-12 0.07 0.25 0.06 TRUE
111 The Cancer Genome Atlas Prostate Adenocarcinoma PYGB 0.21 0.13 enet 5 0.17 2.0e-17 5.37 -6.2 6.0e-10 -0.09 1.00 0.00 TRUE
112 The Cancer Genome Atlas Rectum Adenocarcinoma DUSP15 0.17 0.11 blup 44 0.13 6.6e-04 -7.51 7.0 2.5e-12 -0.74 0.02 0.41 FALSE
113 The Cancer Genome Atlas Skin Cutaneous Melanoma LOC100134868 0.10 0.06 blup 11 0.06 8.7e-03 -3.87 5.5 3.8e-08 -0.13 0.00 0.52 FALSE
114 The Cancer Genome Atlas Stomach Adenocarcinoma COX4I2 0.09 0.03 blup 25 0.03 3.8e-03 -8.81 -7.9 3.0e-15 0.88 0.00 0.71 FALSE
115 The Cancer Genome Atlas Testicular Germ Cell Tumors PIGU 0.10 0.10 lasso 2 0.10 2.8e-04 -4.94 5.2 2.0e-07 0.01 0.03 0.90 FALSE
116 The Cancer Genome Atlas Thyroid Carcinoma C20orf203 0.14 0.04 enet 18 0.06 1.1e-06 -8.87 -6.2 4.2e-10 -0.09 0.57 0.16 FALSE
117 The Cancer Genome Atlas Thyroid Carcinoma COX4I2 0.02 0.03 lasso 2 0.03 1.0e-03 -8.82 -8.8 1.1e-18 0.87 0.02 0.60 FALSE
118 The Cancer Genome Atlas Thyroid Carcinoma MAP1LC3A 0.04 0.00 blup 45 0.01 1.5e-02 3.36 5.4 5.4e-08 0.00 0.02 0.50 FALSE