Best TWAS P=1.05e-25 · Best GWAS P=1.41e-31 conditioned to 4.51e-28
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Not Sun Exposed Suprapubic | TTC3-AS1 | 0.22 | 0.19 | enet | 38 | 0.19 | 7.7e-11 | -2.8 | 5.5 | 3.4e-08 | -0.08 | 1.00 | 0.00 | TRUE |
| 2 | YFS | Blood | CBR1 | 0.03 | 0.00 | bslmm | 497 | 0.01 | 7.9e-04 | 2.8 | 6.1 | 1.4e-09 | -0.01 | 0.06 | 0.02 | TRUE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | CLDN14 | 0.15 | 0.09 | enet | 12 | 0.11 | 7.7e-07 | -11.2 | 7.0 | 3.6e-12 | 0.01 | 0.00 | 1.00 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CLDN14 | 0.05 | 0.04 | lasso | 4 | 0.04 | 5.4e-05 | -11.2 | 10.5 | 1.1e-25 | -0.01 | 0.00 | 1.00 | TRUE |