TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Blood Red Count
:
←
→
chr21:36,744,868-39,261,724
Best TWAS P=1.05e-25 · Best GWAS P=1.41e-31 conditioned to 4.51e-28
37M
37.5M
38M
38.5M
39M
0
5
10
15
20
25
30
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
CLDN14
0.05
0.04
lasso
4
0.04
5.4e-05
-11.2
10.5
1.1e-25
-0.01
0.00
1.00
TRUE
3
The Cancer Genome Atlas
Colon Adenocarcinoma
CLDN14
0.15
0.09
enet
12
0.11
7.7e-07
-11.2
7.0
3.6e-12
0.01
0.00
1.00
TRUE
2
YFS
Blood
CBR1
0.03
0.00
bslmm
497
0.01
7.9e-04
2.8
6.1
1.4e-09
-0.01
0.06
0.02
TRUE
1
GTEx
Skin Not Sun Exposed Suprapubic
TTC3-AS1
0.22
0.19
enet
38
0.19
7.7e-11
-2.8
5.5
3.4e-08
-0.08
1.00
0.00
TRUE