Best TWAS P=1.44e-08 · Best GWAS P=2.11e-07 conditioned to 0.148
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | RRP1B | 0.14 | 0.10 | enet | 13 | 0.11 | 8.0e-08 | -4.6 | -5.2 | 1.8e-07 | 0.86 | 0.05 | 0.95 | FALSE |
| 2 | GTEx | Esophagus Mucosa | PDXK | 0.29 | 0.18 | enet | 12 | 0.24 | 4.1e-16 | -4.9 | -5.7 | 1.4e-08 | 0.75 | 0.04 | 0.96 | TRUE |
| 3 | GTEx | Muscle Skeletal | HSF2BP | 0.10 | 0.04 | lasso | 7 | 0.04 | 1.5e-04 | -4.8 | -5.5 | 3.9e-08 | 0.86 | 0.05 | 0.94 | FALSE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | RRP1B | 0.04 | 0.01 | lasso | 4 | 0.03 | 7.1e-03 | -4.8 | 5.2 | 2.0e-07 | -0.88 | 0.02 | 0.69 | FALSE |