Best TWAS P=1.01e-09 · Best GWAS P=2.25e-24 conditioned to 9.58e-18
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | OR2W3 | 0.04 | 0.01 | bslmm | 474 | 0.00 | 5.7e-02 | 3.0 | 6.1 | 1.0e-09 | 0.16 | 0.08 | 0.09 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LOC148824 | 0.16 | 0.10 | enet | 21 | 0.12 | 1.8e-13 | -3.8 | -5.7 | 1.2e-08 | -0.06 | 0.03 | 0.55 | TRUE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | LOC148824 | 0.20 | 0.10 | blup | 39 | 0.11 | 1.1e-10 | -3.8 | -5.3 | 8.9e-08 | -0.06 | 0.03 | 0.55 | TRUE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | TRIM58 | 0.03 | 0.02 | lasso | 7 | 0.02 | 1.3e-03 | -4.0 | 5.5 | 3.3e-08 | -0.11 | 0.32 | 0.03 | FALSE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | LOC148824 | 0.16 | 0.07 | enet | 15 | 0.13 | 7.6e-08 | -3.8 | -5.3 | 1.4e-07 | -0.04 | 0.01 | 0.58 | FALSE |
| 2 | YFS | Blood | OR2W3 | 0.46 | 0.11 | enet | 38 | 0.26 | 1.3e-85 | -3.0 | 5.1 | 2.9e-07 | -0.14 | 1.00 | 0.00 | FALSE |