TWAS hub - OR2W3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	METSIM	Adipose	0.0438	0.0195	1.2e-02	0.011	0.004	-0.001	0.005	0.001	6.4e-03	8.0e-02	6.8e-01	5.7e-02	2.0e-01
2	NTR	Blood	0.0780	0.0225	4.6e-06	0.022	0.019	0.031	0.022	0.023	9.3e-08	7.3e-07	3.1e-10	7.5e-08	6.0e-08
3	YFS	Blood	0.4569	0.0386	0.0e+00	0.114	0.233	0.262	0.186	0.250	2.4e-35	7.2e-75	1.3e-85	1.6e-58	3.3e-81
4	TCGA	Bladder Urothelial Carcinoma	0.1090	0.0560	1.5e-03	0.048	0.029	0.013	NA	0.032	6.5e-05	1.7e-03	2.4e-02	NA	9.0e-04
5	TCGA	Glioblastoma Multiforme	0.1800	0.0820	2.1e-03	0.032	0.074	0.049	NA	0.078	3.7e-02	3.0e-03	1.4e-02	NA	2.3e-03
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.0686	0.0281	2.9e-05	0.043	0.053	0.027	NA	0.034	1.1e-05	1.4e-06	4.5e-04	NA	1.0e-04
7	TCGA	Brain Lower Grade Glioma	0.1567	0.0396	0.0e+00	0.137	0.161	0.175	NA	0.173	2.3e-15	6.2e-18	2.2e-19	NA	3.5e-19
8	TCGA	Thyroid Carcinoma	0.1320	0.0420	2.6e-06	0.013	0.058	0.069	NA	0.044	1.7e-02	2.4e-06	3.0e-07	NA	3.9e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Blood Platelet Count	10.2	118.0	198.8	-10.8	-10.0	-11.0	-14.1	-11.5	-4.9	-11.1	-11.3
Suffer from ‘nerves’	4.7	7.4	10.6	-2.7	-1.9	-3.0	-1.5	-3.1	-3.1	-3.3	-2.7
Nervous feelings	4.0	7.5	11.9	-2.2	-2.4	-3.4	-2.5	-2.5	-2.2	-3.2	-3.2
Ever unenthusiastic/disinterested for a whole week	3.8	4.6	9.4	-3.1	-2.1	-1.6	-0.5	-2.4	-1.5	-2.4	-2.6
Illnesses of father: None of the above (group 1)	3.8	4.7	7.7	-1.8	-2.4	-2.8	-1.0	-1.8	-2.3	-2.3	-2.5
Headache pain in last month	3.5	6.0	9.4	-1.7	-1.1	-2.3	-2.9	-3.1	-2.7	-3.0	-2.0
Worry (Nagel 2018)	3.4	7.3	10.2	-3.1	-2.2	-3.0	-2.6	-2.6	-1.7	-3.2	-2.8
Neuroticism score	3.1	6.5	10.0	-2.1	-2.4	-2.7	-2.7	-2.5	-1.6	-2.8	-3.2
Age started oral contraceptive pill	3.1	3.9	6.9	2.1	1.8	2.6	1.3	1.1	1.7	2.2	2.5
Ever depressed for a whole week	3.1	3.8	7.2	-2.6	-2.0	-1.9	-0.1	-1.5	-1.4	-2.2	-2.7
Lung cancer (father)	3.0	3.5	10.4	-3.2	-2.0	-0.8	-0.3	-2.0	-1.3	-1.6	-2.2
Alcohol usually taken with meals	2.9	4.8	8.6	1.8	1.7	2.3	0.1	2.4	2.3	2.9	2.7
Breast cancer (self-reported)	2.9	3.4	6.7	1.1	2.2	1.5	1.9	2.1	1.2	1.8	2.6
Maternal smoking around birth	2.6	3.8	9.7	-3.1	-1.2	-1.1	-2.5	-2.3	-1.5	-1.8	-1.1
Age at first live birth	2.4	4.2	7.6	2.6	2.3	2.8	-0.4	0.9	1.6	2.4	2.2
Smoking status: Current	2.4	3.8	6.9	-2.6	-1.9	-2.0	-0.7	-1.6	-1.6	-1.9	-2.6
Guilty feelings	2.4	3.6	5.1	-2.2	-0.3	-1.9	-1.9	-2.0	-2.0	-1.9	-2.3
Ever had hysterectomy (womb removed)	2.3	2.6	4.7	-1.6	-2.2	-1.6	-1.6	-1.7	-1.5	-1.5	-1.1
Medication: Levothyroxine sodium	2.3	4.0	7.1	0.9	2.1	2.2	0.9	2.1	1.9	2.7	2.3
Hypothyroidism/myxoedema (self-reported)	2.3	4.5	8.7	0.8	2.5	2.1	1.2	2.4	2.2	3.0	2.1
Chronic bronchitis/emphysema (mother)	2.2	2.6	5.5	-1.8	-1.7	-2.0	-0.3	-0.6	-0.9	-1.9	-2.3
Blood Red Count	2.1	20.4	37.3	6.1	5.0	5.1	5.1	3.1	0.3	4.1	4.7
Commuting to job workplace: Walk	2.1	2.3	4.3	1.0	1.5	1.8	1.5	1.2	0.9	1.6	2.1
Unable to work because of sickness or disability	2.1	2.7	6.2	-2.2	-0.4	-0.5	-2.0	-2.5	-2.0	-1.1	-1.0
Bilateral oophorectomy (both ovaries removed)	2.0	2.3	6.0	-2.4	-1.8	-1.2	-0.6	-1.2	-1.3	-1.3	-1.7
Supplements: Glucosamine	2.0	2.6	4.4	-1.8	-1.4	-1.6	-2.1	-1.7	-1.8	-1.5	-0.7
Medication: Blood pressure	2.0	3.8	5.1	-1.7	-1.8	-2.0	-1.7	-2.2	-2.3	-2.3	-1.4
Hypothyroidism (self reported)	1.9	4.3	7.2	1.2	2.7	1.9	1.8	2.1	1.4	2.6	2.5
Neuroticism	1.9	4.6	6.8	-2.5	-2.0	-2.3	-1.6	-2.0	-1.3	-2.4	-2.6
Current tobacco smoking	1.9	3.2	7.3	-2.7	-1.5	-1.9	-0.1	-1.2	-1.4	-1.5	-2.6
Age at last live birth	1.9	2.7	4.7	0.9	2.2	2.0	0.2	1.6	2.1	2.0	1.2
Eye problems/disorders: Glaucoma	1.9	2.2	4.8	1.5	1.0	1.8	0.4	1.4	2.2	1.7	1.3
Noisy workplace	1.8	2.2	5.3	-1.6	-1.6	-2.3	0.4	-0.5	-1.1	-1.5	-1.8
Pulse wave reflection index	1.8	2.2	4.5	1.8	1.2	1.5	1.4	0.4	0.6	2.1	1.9
Illnesses of father: Heart disease	1.8	2.5	5.9	2.4	1.4	1.7	0.6	1.4	1.9	1.3	1.3
Risk taking	1.8	2.7	5.2	-0.4	2.3	1.9	1.6	1.1	1.0	2.0	1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.3	6.1	0.4	-2.5	-1.8	-0.9	-1.4	-0.3	-1.9	-1.5
Ever had prostate specific antigen (PSA) test	1.7	1.9	4.6	-0.5	-2.0	-2.1	-0.1	-0.1	-0.6	-1.4	-2.0
Neuroticism (2016)	1.6	2.3	5.8	-0.6	-0.9	-1.1	-1.6	-1.5	-1.6	-1.7	-2.4
Frequency of tenseness / restlessness in last 2 weeks	1.6	2.6	4.8	-0.7	-1.4	-2.2	-1.2	-1.6	-0.9	-2.0	-2.2
Frequency of tiredness / lethargy in last 2 weeks	1.6	2.7	9.1	-0.2	-0.8	-1.7	-3.0	-1.8	-1.0	-1.4	-1.5
Glaucoma (self-reported)	1.6	1.9	4.4	-0.0	1.4	2.1	0.9	1.1	1.9	1.4	1.1
Leg pain on walking	1.6	2.0	3.6	-0.1	-1.7	-1.3	-1.2	-1.9	-1.8	-1.5	-0.9
Age at First Birth	1.5	2.2	3.8	1.4	1.3	1.5	0.2	1.8	1.8	1.9	1.2
Pulse rate	1.5	2.6	4.2	-2.1	-1.8	-0.7	-1.4	-1.8	-1.6	-1.7	-1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.5	2.3	6.2	-2.5	-1.1	-1.4	0.4	-0.5	-0.3	-1.6	-2.4
Health satisfaction	1.5	1.9	7.0	-0.7	-0.4	-1.0	-2.6	-1.6	-1.2	-1.1	-1.2
Medication for cholesterol	1.5	2.3	3.8	1.4	1.6	1.4	0.9	1.7	1.7	2.0	1.2
Ever taken oral contraceptive pill	1.5	1.7	3.7	1.3	1.0	1.9	0.6	1.1	1.7	1.4	0.7
Diverticular disease/diverticulitis (self-reported)	1.4	1.6	3.4	0.8	1.5	1.0	0.8	1.9	1.8	1.3	0.6
Number of incorrect matches in round	1.4	2.3	4.4	-2.1	-1.1	-1.1	-0.9	-1.7	-1.9	-1.1	-1.7
Heart attack	1.4	1.8	4.9	-1.7	-0.2	-0.3	-1.1	-2.2	-1.5	-1.4	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.8	8.0	-2.8	-1.0	-1.0	0.4	-0.1	-0.6	-0.9	-1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.6	4.7	-2.2	-1.0	-0.3	-0.8	-1.5	-1.4	-1.3	-0.8
Mineral and other dietary supplements	1.4	1.9	3.7	1.6	1.4	0.7	1.9	1.9	1.6	0.8	0.2
Irritability	1.4	2.4	5.4	-0.2	-2.3	-1.7	-1.0	-1.6	-0.8	-2.1	-1.7
Neuroticism (Nagel 2018)	1.3	3.0	4.3	-2.0	-1.3	-1.9	-1.7	-1.6	-1.0	-1.9	-2.1
Worry too long after embarrassment	1.3	2.2	6.4	-1.3	-1.5	-1.7	-0.9	-1.0	-0.7	-1.4	-2.5
Knee pain experienced in last month	1.3	2.0	4.9	-2.2	-0.4	-1.8	-1.2	-1.0	-1.4	-1.0	-1.3
Average weekly red wine intake	1.3	1.9	3.9	1.6	0.6	1.4	-0.3	1.3	1.3	1.6	2.0
Pain experienced in last month	1.3	2.1	4.2	2.1	0.4	1.1	1.5	1.8	1.7	1.0	1.4
Heart attack/myocardial infarction (self-reported)	1.3	1.7	4.5	-1.7	-0.2	-0.3	-1.2	-2.1	-1.4	-1.3	-1.0
Depression (Nagel 2018)	1.2	1.8	3.7	-0.3	-1.9	-1.8	-0.8	-1.7	-1.0	-1.4	-1.1
Schizophrenia (2018)	1.2	2.6	5.7	2.4	1.1	1.4	1.8	1.8	1.5	1.5	0.5
Prostate Cancer	1.2	1.7	3.0	0.1	-1.6	-1.7	0.5	-0.8	-1.0	-1.7	-1.7
Loud music exposure frequency	1.2	1.3	2.7	-1.1	-0.7	-1.2	-0.3	-0.9	-1.0	-1.6	-1.6
Birth weight	1.2	2.5	5.1	1.1	0.8	1.9	2.3	1.8	1.4	2.0	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	5.6	0.5	0.2	1.2	2.4	1.2	1.1	1.1	0.7
Friendships satisfaction	1.2	1.5	5.3	0.3	-2.3	-1.2	-1.0	-0.6	0.3	-1.2	-1.5
Average weekly champagne plus white wine intake	1.2	1.6	4.6	-1.2	1.0	-0.1	-2.1	-1.8	-1.3	-0.9	-0.2
Major Depression (MDD)	1.1	1.4	4.7	2.2	0.4	1.4	0.7	0.5	1.1	1.4	0.7
Diabetes (father)	1.1	1.3	2.7	-1.5	-0.7	-0.4	-0.4	-1.6	-1.5	-1.3	-1.0
Pack years adult smoking proportion	1.1	1.6	3.0	-1.7	-0.9	-1.5	-0.6	-1.0	-0.9	-1.4	-1.7
Happiness	1.1	1.3	2.6	-1.6	-0.6	-1.1	-1.6	-1.2	-0.1	-1.2	-0.9
Gout (self-reported)	1.1	1.5	3.1	-1.2	-1.8	-1.5	-0.9	-0.6	-0.2	-1.2	-1.6
Exposure to tobacco smoke outside home	1.1	1.5	4.1	-0.5	-0.6	-1.2	0.5	-1.4	-2.0	-1.6	-1.0
Shortness of breath walking on level ground	1.1	1.3	1.8	0.3	-1.2	-1.3	-0.8	-1.1	-1.3	-1.3	-1.2
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	2.6	-1.3	-0.7	-0.7	-0.6	-1.5	-1.6	-1.2	-0.7
Medication: Bendroflumethiazide	1.1	1.7	2.7	-1.0	-1.1	-1.6	0.6	-1.2	-1.7	-1.6	-1.4
Commuting to job workplace: Cycle	1.1	1.3	4.2	0.3	-0.7	-1.0	-2.1	-1.2	-1.3	-1.1	-0.7
HbA1C	1.0	1.1	2.5	1.1	1.0	1.0	1.6	1.3	1.0	0.5	0.4
Smoking Status	1.0	2.5	10.7	-3.3	-1.0	-0.7	-0.5	-1.2	-1.2	-1.2	-1.7
Ever used hormone-replacement therapy (HRT)	1.0	1.2	3.4	0.0	0.9	1.5	0.2	0.2	1.1	1.4	1.9
Multivitamins +/- minerals	1.0	1.3	2.7	-1.6	-1.7	-1.2	-0.9	-0.4	-0.6	-0.7	-1.4
Alcohol intake versus 10 years previously	1.0	1.4	3.1	-1.4	-1.4	-1.8	-1.2	-0.7	-0.4	-0.9	-1.2
Worrier / anxious feelings	1.0	1.8	4.9	-0.4	-1.3	-1.7	-0.8	-1.1	-0.4	-1.6	-2.2
Mouth/teeth dental problems: Loose teeth	1.0	1.2	3.2	-1.1	-0.9	-0.4	-0.7	-1.2	-0.5	-1.2	-1.8
Overall health rating	1.0	2.1	5.5	-0.6	-0.8	-1.8	-1.6	-1.3	-1.0	-1.4	-2.3
Medication: Aspirin	1.0	1.3	4.0	0.5	-1.0	-0.7	0.0	-2.0	-1.8	-1.1	-0.4
Mood swings	1.0	1.9	3.8	-1.1	-1.2	-1.5	-1.3	-1.1	-0.9	-1.5	-1.9
Medication: Aspirin	1.0	1.3	4.3	0.4	-0.7	-0.7	-0.1	-2.1	-1.8	-1.2	-0.4
Medication: Lisinopril	1.0	1.2	3.3	-1.6	1.5	0.7	-0.3	0.6	0.2	0.9	1.8
Heart disease (siblings)	1.0	1.2	3.3	-1.8	-1.7	-0.7	0.8	0.9	1.0	-0.2	-0.8
Schizophrenia (2014)	0.9	1.9	5.3	2.3	1.0	1.5	2.0	1.1	0.6	0.9	0.5
Type 2 Diabetes (T2D) (2012)	0.9	1.1	2.8	-1.7	-1.0	-0.7	-1.0	-1.0	-0.7	-0.8	-1.1
Medication: Co-codamol	0.9	1.0	2.5	0.5	1.6	1.4	0.2	0.3	-0.3	1.2	1.4
Hayfever, allergic rhinitis or eczema	0.9	2.0	4.5	0.2	-1.8	-2.1	-1.5	-0.1	-0.1	-1.6	-1.9
Chronic bronchitis/emphysema (father)	0.9	1.1	2.9	0.7	1.7	1.3	0.4	0.6	0.5	0.9	1.3
Had other major operations	0.9	1.1	3.1	1.2	0.7	1.2	1.8	0.6	0.5	0.5	1.2
Peak expiratory flow (PEF)	0.9	2.2	5.8	2.4	1.3	1.3	0.5	1.3	1.5	1.7	1.1
Ever highly irritable/argumentative for 2 days	0.9	1.1	2.8	-1.1	-1.5	-0.4	0.4	-0.9	-0.5	-1.0	-1.7
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	2.7	-0.2	-1.6	-0.7	-1.0	-1.3	-0.6	-1.4	-1.1
Medication: Ventolin 100micrograms inhaler	0.9	1.2	2.8	0.2	-1.3	-0.9	-0.7	-1.1	-1.0	-1.1	-1.7
Back pain experienced in last month	0.9	1.4	5.3	-2.3	0.8	0.7	-0.7	-1.0	-1.7	0.0	0.1
Pack years of smoking	0.9	1.4	2.5	-1.5	-0.8	-1.4	-0.5	-1.0	-0.8	-1.4	-1.6
Frequency of depressed mood in last 2 weeks	0.8	1.1	2.1	0.2	-1.4	-1.4	-0.2	-1.1	-0.7	-1.2	-1.3
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	2.1	1.1	0.4	0.6	1.4	1.1	0.7	0.7	1.3
Length of working week for main job	0.8	0.9	2.3	-0.3	-0.3	-0.8	-1.1	-1.5	-1.4	-1.0	-0.4
Tense / ‘highly strung’	0.8	1.3	5.5	-2.3	0.1	-0.4	-1.4	-1.1	-0.6	-0.7	-1.0
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	2.1	0.5	-1.5	-0.5	-0.6	-1.1	-1.1	-1.3	-1.0
Arm fat percentage (left)	0.8	3.4	7.7	-1.7	-1.2	-1.8	-1.0	-1.9	-2.8	-2.2	-1.6
Long-standing illness, disability or infirmity	0.8	1.2	2.5	0.8	-0.7	-0.8	-0.6	-1.3	-1.4	-1.1	-1.6
Medication: Gliclazide	0.8	0.9	2.6	1.5	0.5	0.5	1.6	1.0	0.4	0.8	0.6
Supplements: Fish oil (including cod liver oil)	0.8	1.0	2.7	-1.6	-0.4	0.4	-1.5	-1.4	-0.9	0.3	0.6
Alcohol drinker status: Never	0.8	1.0	3.5	-0.6	-1.1	-0.3	-1.3	-1.9	-0.7	-0.9	0.1
Ever smoked	0.8	1.5	6.8	-2.6	-0.3	-0.6	1.1	-0.1	-0.1	-0.5	-1.7
Vascular/heart problems diagnosed by doctor	0.8	2.1	3.6	1.5	1.0	1.1	1.1	1.9	1.7	1.7	1.2
Basal cell carcinoma (self-reported)	0.8	1.0	3.3	-0.3	0.5	0.2	1.8	1.7	1.0	0.6	0.0
Crohns Disease (2012)	0.7	1.1	2.6	-1.5	1.1	0.5	-1.6	-0.7	-0.8	-0.0	1.0
Financial difficulties in last 2 years	0.7	0.9	3.3	-0.5	1.8	0.5	0.0	1.0	0.4	1.2	0.9
Allergy	0.7	1.5	3.2	-1.1	1.7	1.5	0.5	0.5	0.6	1.4	1.8
Falls in the last year	0.7	1.0	2.3	-1.5	-0.8	-1.2	-1.0	-0.8	-0.3	-1.1	-0.9
Forced expiratory volume in 1-second (FEV1)	0.7	2.4	4.1	1.5	1.4	1.3	1.3	2.0	1.6	2.0	1.1
Asthma	0.7	1.3	4.9	2.2	1.2	1.3	1.2	0.3	0.7	0.5	0.2
Birth weight of first child	0.7	1.3	4.3	2.1	0.3	0.9	1.8	0.5	-0.0	0.8	1.0
Migraine (self-reported)	0.7	0.9	2.7	0.4	-0.0	-0.5	-1.7	-1.6	-0.6	-1.0	-0.4
Supplements: Vitamin C	0.7	0.9	2.2	-0.3	0.2	1.2	0.1	0.7	0.8	1.5	1.3
Smoking status: Previous	0.7	1.0	2.5	-1.1	1.6	0.9	1.2	0.9	0.8	0.7	0.6
Qualifications: nursing, teaching	0.7	1.1	3.1	-0.1	1.2	1.2	-0.6	0.7	1.0	1.0	1.8
Commuting to job workplace: Public transport	0.7	0.9	4.0	2.0	-0.9	0.2	0.5	1.0	0.6	0.4	0.6
Cholesterol lowering medication	0.7	1.0	2.8	-0.9	-0.6	-0.3	-0.3	-1.4	-1.7	-1.2	-0.7
Lupus	0.6	0.9	4.1	-2.0	0.3	0.1	1.0	-0.1	-1.2	-0.4	-0.4
Ulcerative Colitis	0.6	0.8	4.8	-0.4	1.0	0.1	-2.2	0.0	0.5	-0.2	0.8
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	1.1	1.1	-0.7	0.8	0.6	0.8	0.8	0.5	0.8
Trunk fat percentage	0.6	2.3	4.0	-1.6	-0.9	-1.9	-0.6	-1.3	-2.0	-1.9	-1.3
Hand grip strength (right)	0.6	1.6	3.0	1.5	1.4	0.6	1.6	1.7	1.2	1.0	0.4
Qualifications: None of the above	0.6	1.3	5.6	-2.4	-0.4	-1.2	-0.1	-0.9	-0.8	-0.9	-0.9
Mouth/teeth dental problems	0.6	1.0	2.8	0.5	1.4	0.9	0.3	0.9	0.5	1.0	1.7
Fluid intelligence score	0.6	1.2	2.5	0.9	0.7	1.5	-1.6	-0.4	0.8	1.0	1.2
Medication: Cholesterol lowering	0.6	1.0	3.6	0.7	0.5	0.5	1.9	1.2	0.5	1.1	0.4
Impedance of arm (left)	0.6	2.9	4.8	-1.0	-2.2	-2.0	-1.0	-1.8	-1.6	-1.8	-1.9
Medication for cholesterol, blood pressure or diabetes	0.6	1.1	2.0	-0.9	-1.0	-0.6	-1.3	-1.4	-1.2	-1.1	-0.2
Body fat percentage	0.6	2.3	4.3	-1.8	-0.7	-1.8	-0.7	-1.2	-2.1	-1.8	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	2.2	0.5	-0.3	0.7	0.3	1.5	1.1	1.2	0.6
Medication: Blood pressure	0.6	1.1	1.9	0.8	1.0	0.9	1.2	1.4	1.4	1.0	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	1.3	0.6	-1.1	-1.1	0.0	-0.5	-0.8	-0.8	-1.0
Illnesses of siblings: Diabetes	0.6	0.7	3.2	-0.0	-0.3	-0.8	-0.4	-0.8	-1.8	-0.8	-0.2
Asthma (self-reported)	0.6	1.3	4.8	2.2	1.3	1.2	1.2	0.4	0.7	0.5	0.3
Osteoporosis (self-reported)	0.6	0.8	4.2	0.6	-0.0	-0.2	-0.5	-1.1	-2.0	-0.3	-0.1
Financial situation satisfaction	0.6	0.7	1.4	-0.9	-1.2	-1.2	-0.5	-0.2	-0.2	-1.1	-0.8
Medication: Atorvastatin	0.6	0.7	4.8	0.3	0.2	0.0	2.2	0.6	-0.1	0.2	-0.4
Alzheimer’s Disease (in father)	0.5	0.5	3.0	-0.2	-1.7	-0.3	-0.2	-0.6	-0.4	-0.7	-0.1
Irritable Bowel Disease (IBD)	0.5	1.1	3.3	-0.0	1.8	0.3	-0.9	1.1	0.8	1.0	1.2
Fasting Glucose	0.5	0.6	2.0	1.1	0.6	-0.5	1.4	0.8	0.3	0.3	0.3
Primary Biliary Cirrhosis	0.5	0.7	2.9	-1.4	0.6	0.3	1.7	0.1	-0.6	0.2	0.2
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	1.4	0.9	0.9	0.4	-0.7	1.1	1.2	0.5	0.6
Vitamin and mineral supplements	0.5	0.7	2.3	1.5	1.1	0.6	1.0	-0.1	0.1	0.1	0.7
Medication: Metformin	0.5	0.7	1.4	0.2	-0.3	-1.0	-0.9	-0.9	0.0	-1.2	-1.1
Severe depression (siblings)	0.5	0.6	1.0	0.4	-0.4	-1.0	-0.9	-0.9	-0.7	-0.9	-0.5
Townsend deprivation index at recruitment	0.5	0.7	3.5	-0.2	-0.0	0.6	1.9	1.0	0.6	0.7	0.6
Past tobacco smoking	0.5	0.9	4.9	2.2	-0.6	-0.3	-1.0	-0.3	-0.4	0.0	0.6
Pain all over the body in last month	0.5	0.6	3.5	0.6	0.7	-0.3	-1.9	-0.3	-0.3	0.0	0.1
Arm fat percentage (right)	0.5	1.9	5.1	-1.4	-0.7	-1.0	-1.0	-1.5	-2.3	-1.6	-1.0
Mouth/teeth dental problems: Dentures	0.5	0.9	1.9	-0.2	-1.1	-1.3	1.4	-0.1	-0.7	-0.5	-1.3
Medication: Amlodipine	0.5	0.7	1.3	-0.4	-1.0	-1.2	-0.5	-0.8	-0.7	-1.0	-0.8
Leg fat percentage (right)	0.5	1.6	4.0	-2.0	-0.1	-1.4	-0.7	-1.0	-1.7	-1.3	-1.1
Eye problems/disorders: None of the above	0.5	0.6	1.3	-0.8	-0.2	-1.0	0.3	-0.9	-1.1	-0.7	-0.7
Neck or shoulder pain in last month	0.5	0.7	3.5	-1.2	-0.3	-0.3	-1.9	-0.4	0.5	0.0	-0.2
Medication: Ibuprofen	0.5	0.6	1.8	1.1	-0.5	0.3	1.4	0.9	0.6	0.3	0.7
Number of full sisters	0.5	0.6	2.0	-1.4	0.9	0.7	-0.4	0.2	0.7	0.5	1.0
Family relationship satisfaction	0.5	0.6	1.7	-0.3	-0.8	-0.6	1.0	0.6	1.3	-0.2	-0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	2.3	0.3	1.4	0.7	0.7	1.4	1.5	1.1	0.1
Eye problems/disorders: Cataract	0.5	0.6	0.9	-0.6	-0.9	-0.9	-1.0	0.4	0.5	-0.8	-0.8
Hearing aid user	0.5	0.5	1.6	1.2	0.6	-0.7	-0.8	-0.8	-0.7	-0.0	0.2
Pain type(s) experienced in last month: Hip pain	0.5	0.7	1.7	-0.8	-1.3	-0.7	-0.0	-0.7	-0.7	-0.7	-0.9
Average weekly beer plus cider intake	0.5	0.7	3.1	-0.6	-1.8	-0.6	0.2	-0.5	0.2	-1.0	-0.7
Alcohol drinker status: Previous	0.5	0.5	1.2	0.6	0.0	0.4	-0.9	-1.1	-0.9	-0.7	-0.6
Bipolar Disorder or Schizophrenia	0.4	1.0	3.3	1.8	0.9	1.1	0.9	0.6	0.8	0.7	0.1
Schizophrenia vs Biploar Disorder	0.4	0.5	2.1	1.5	-0.2	0.3	0.9	0.9	0.5	0.5	0.0
Alzheimer’s Disease (in mother)	0.4	0.5	1.3	1.1	0.7	0.8	-0.1	-0.4	0.9	0.5	0.8
Alzheimer’s Disease (including proxy)	0.4	0.6	1.8	1.3	-0.3	0.8	0.6	-0.5	0.9	0.5	0.6
Ulcerative Colitis (UC)	0.4	0.8	2.9	0.0	1.7	-0.1	-0.9	0.9	0.7	0.5	1.1
Verbal and Numeric Reasoning (VNR)	0.4	1.1	6.7	0.3	-0.2	0.7	-2.6	-0.9	0.2	0.2	0.5
Breast Cancer	0.4	0.9	2.7	0.4	0.6	1.3	0.2	0.9	0.8	0.9	1.6
Ovarian Cancer	0.4	0.5	2.1	0.2	-0.4	-0.2	0.3	-1.0	-1.5	0.3	0.7
Lung FEV1/FVC ratio	0.4	1.9	5.3	0.9	1.4	1.5	0.5	1.0	0.6	1.9	2.3
Hearing difficulty/problems: Yes	0.4	0.7	1.4	0.9	-0.5	-0.6	-0.4	-1.2	-1.0	-1.1	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.8	1.9	1.2	0.6	0.2	-0.1	1.2	1.4	1.1	0.4
Qualifications: CSEs or equivalent	0.4	0.6	1.6	-0.8	-1.0	-0.1	-0.8	0.2	0.8	-0.3	-1.3
Serious illness, injury or assault to yourself	0.4	0.5	1.3	0.4	0.1	1.0	0.1	0.4	1.1	1.0	0.2
High blood pressure	0.4	1.0	1.6	-0.8	-0.6	-0.9	-1.2	-1.3	-1.0	-1.2	-0.7
Stomach or abdominal pain in last month	0.4	0.5	0.8	-0.8	-0.4	-0.9	-0.7	0.7	0.7	-0.2	-0.9
High blood pressure (mother)	0.4	0.5	1.6	-0.4	-0.3	-0.7	-0.0	-1.2	-0.5	-1.3	-0.5
Trunk fat mass	0.4	1.5	3.1	-1.5	-0.4	-1.4	-0.5	-1.1	-1.8	-1.5	-1.0
Hearing difficulty/problems with background noise	0.4	0.7	1.7	-1.3	-0.7	-0.2	-0.2	-0.8	-1.1	-0.8	-0.7
Had menopause	0.4	0.5	1.3	-1.0	0.2	0.4	-0.2	0.7	1.1	0.3	1.1
Forced vital capacity (FVC)	0.4	1.4	2.9	0.8	1.0	0.8	1.1	1.7	1.5	1.6	0.2
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	1.4	1.2	1.0	0.7	-0.1	0.4	0.2	0.5	0.8
Illnesses of siblings	0.4	0.6	2.9	1.7	0.8	0.6	0.1	-0.3	-0.3	0.4	0.8
Time employed in main current job	0.4	0.4	1.0	-0.5	-0.2	-0.6	-1.0	-0.8	-0.0	-0.7	-0.7
Hair/balding pattern: Pattern 3	0.4	0.6	2.5	-0.4	-0.8	-0.9	0.0	-0.0	-0.4	-0.7	-1.6
Qualifications: A levels/AS levels or equivalent	0.4	0.8	1.8	1.2	0.9	0.6	-0.4	0.8	1.4	1.0	0.7
Illnesses of mother	0.4	0.5	1.6	0.3	0.5	1.0	0.4	0.8	0.6	1.2	0.6
Emphysema/chronic bronchitis	0.4	0.5	0.9	0.4	0.3	0.9	0.8	0.8	0.6	0.8	-0.7
Medication: Omeprazole	0.4	0.5	1.4	-1.2	0.6	-0.1	-0.3	-0.3	-1.2	0.3	0.5
Medication: Seretide 50 evohaler	0.4	0.5	1.3	0.3	-0.7	-0.3	0.5	-0.6	-1.1	-0.6	-1.0
Mean time to correctly identify matches	0.4	0.8	1.7	-1.3	-1.0	-1.2	-0.2	-0.2	0.2	-1.1	-0.9
Pulse rate, automated reading	0.4	1.2	3.8	-0.7	-1.3	-0.4	0.1	-1.2	-1.9	-1.0	-0.9
Diabetes diagnosed by doctor	0.4	0.7	1.7	0.6	-0.2	-1.3	0.4	0.3	0.8	-1.1	-1.1
Arm fat mass (left)	0.4	1.5	4.9	-1.3	-0.3	-0.8	-0.5	-1.3	-2.2	-1.4	-0.7
Number of self-reported non-cancer illnesses	0.4	0.6	1.6	-0.4	-0.3	0.1	0.3	-1.0	-1.0	-1.1	-1.2
Leg fat percentage (left)	0.4	1.5	3.5	-1.9	0.0	-1.2	-0.9	-1.0	-1.7	-1.1	-0.9
Myopia	0.4	0.5	1.2	-0.5	1.1	0.1	-0.7	-1.1	-0.5	-0.3	0.9
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.7	-1.3	0.8	0.1	-0.2	-0.3	-1.1	0.4	0.5
Supplements: Calcium	0.4	0.4	1.6	-0.9	-1.3	-0.4	-0.1	-0.6	-0.6	-0.2	-0.1
Bipolar Disorder (2018)	0.3	0.4	1.5	-0.1	-0.1	0.0	-0.8	-1.2	-0.6	-0.8	-0.5
Crohns Disease (2017)	0.3	0.7	2.0	-0.3	1.4	0.8	-0.4	0.9	0.3	0.9	1.1
Reaction Time	0.3	0.5	1.0	-0.1	-0.8	-0.9	-0.3	0.1	0.9	-1.0	-0.8
Bipolar Disorder (2011)	0.3	0.3	1.0	0.0	0.0	0.0	-0.1	-0.9	-1.0	0.0	0.6
Body Mass Index (BMI) (2010)	0.3	0.5	1.6	-0.1	0.8	1.3	0.6	0.2	-0.3	0.7	0.7
Mean Putamen Volume	0.3	0.3	0.9	0.5	0.7	-0.2	0.9	0.8	0.2	0.3	-0.3
Allergy or Eczema	0.3	0.9	2.3	0.8	-0.7	-1.5	-0.9	0.1	-0.1	-1.1	-1.3
Respiratory disease	0.3	0.6	2.0	1.4	0.4	0.5	0.9	-0.6	-0.4	-0.5	-0.8
Type 2 Diabetes (T2D) (2018)	0.3	0.5	1.0	0.4	-0.3	-1.0	0.9	0.5	0.6	-0.9	-0.6
Relative age of first facial hair	0.3	0.7	1.7	1.1	0.6	0.5	1.3	0.1	-1.3	0.5	0.5
Angina	0.3	0.4	1.4	-0.5	0.5	0.4	1.2	0.6	-0.1	0.8	0.3
Average weekly fortified wine intake	0.3	0.3	0.9	0.6	-0.3	0.6	-0.9	-0.1	-0.4	0.0	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	2.4	-0.4	-0.7	-1.5	-0.5	-0.3	-0.1	-0.7	-1.2
Diabetes (self-reported)	0.3	0.5	1.4	-0.1	-0.1	-1.0	0.1	0.1	0.5	-1.1	-1.2
Medication: Ramipril	0.3	0.4	2.5	-0.1	0.4	0.6	1.6	0.2	0.0	0.0	-0.2
Father’s age at death	0.3	0.4	1.3	0.0	0.0	-1.1	-1.1	0.0	-0.5	-0.4	-0.7
Number of live births	0.3	0.4	2.1	-1.5	-0.1	-0.7	-0.4	0.4	0.0	-0.3	-0.3
Depression (self-reported)	0.3	0.4	1.7	0.1	-0.6	-0.1	0.8	-0.2	0.1	-0.4	-1.3
Medication: Lansoprazole	0.3	0.4	1.5	-0.0	1.2	0.4	0.5	0.5	-0.7	0.4	0.0
Arm fat mass (right)	0.3	1.2	3.9	-1.2	-0.4	-0.8	-0.6	-1.2	-2.0	-1.3	-0.6
Hair/balding pattern: Pattern 4	0.3	0.6	3.5	0.7	-0.8	-0.3	1.9	0.3	0.5	-0.4	0.2
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	1.3	0.3	1.1	0.6	0.4	0.9	0.7	0.6	-0.3
Comparative body size at age 10	0.3	0.9	2.6	0.9	-1.1	-0.3	1.6	1.0	0.5	-0.1	-1.2
Number of full brothers	0.3	0.4	1.7	-1.3	0.2	0.5	0.4	0.3	0.7	0.5	0.4
Pulse wave peak to peak time	0.3	0.3	1.0	-0.4	1.0	-0.3	-0.7	0.8	0.4	-0.2	-0.3
Qualifications: College or University degree	0.3	1.0	3.5	1.3	-0.1	0.3	-1.9	-1.0	-0.5	0.1	1.2
Medication: Allopurinol	0.3	0.5	2.2	-0.1	-1.5	-0.7	-0.1	-0.4	-0.1	-0.6	-0.5
Whole body fat mass	0.3	1.2	2.9	-1.6	-0.2	-1.0	-0.5	-0.9	-1.7	-1.2	-0.8
Alcohol intake frequency.	0.3	0.6	0.9	-0.6	-1.0	-0.7	-0.7	-0.9	-0.9	-0.8	-0.6
Commuting to job workplace: Car/motor vehicle	0.3	0.3	1.4	-0.4	0.7	0.5	1.2	0.3	0.4	0.4	-0.1
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.4	0.4	-0.8	-1.2	0.5	-0.0	0.4	-0.1	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	2.0	-1.4	0.3	-0.5	-0.1	0.2	0.1	-0.0	-0.2
Osteoarthritis (self-reported)	0.3	0.3	1.3	-0.6	0.2	0.6	0.3	-0.3	-0.5	-0.1	1.2
Mother’s age at death	0.3	0.4	1.3	0.4	0.4	-0.2	0.4	1.2	1.1	0.5	-0.3
Tinnitus: Yes, now most or all of the time	0.3	0.4	0.9	0.8	-0.5	-0.9	0.9	-0.1	-0.5	-0.5	-0.3
Illnesses of father: High blood pressure	0.3	0.4	0.9	0.8	0.9	0.6	0.4	0.7	0.5	0.2	0.1
Number of operations (self-reported)	0.3	0.5	1.5	-1.2	1.0	0.8	0.8	0.2	-0.3	-0.0	0.1
Leg fat mass (left)	0.3	1.1	2.7	-1.4	0.0	-1.0	-0.5	-0.9	-1.6	-1.2	-0.8
Depressed Affect (Nagel 2018)	0.2	0.5	1.7	-0.8	-0.4	-0.7	-1.3	-0.5	0.0	-0.6	-0.7
HDL Cholesterol	0.2	0.4	2.4	-0.1	-0.3	0.1	-1.6	-0.1	0.8	-0.2	-0.2
Rheumatoid Arthritis	0.2	0.3	0.8	0.2	0.9	0.5	-0.2	0.5	0.6	0.6	0.3
Triglycerides	0.2	0.3	1.0	0.7	-0.4	-0.1	1.0	0.3	0.2	0.1	-0.5
Blood White Count	0.2	1.5	4.9	2.2	0.8	0.6	1.4	-0.2	-2.0	0.3	0.3
Waist Hip Ratio (WHR)	0.2	1.0	2.8	-1.7	-1.0	-0.5	1.3	-0.2	-1.0	-0.2	-1.2
Chronotype (morning person)	0.2	0.5	1.1	0.7	1.1	0.6	0.8	0.5	0.1	0.5	1.1
Hand grip strength (left)	0.2	0.6	1.6	0.4	0.2	-0.0	1.2	1.0	1.0	0.2	-0.8
Number of treatments/medications taken	0.2	0.4	1.4	-0.5	-0.6	0.0	0.4	-0.6	-1.2	-0.2	-0.7
Average weekly spirits intake	0.2	0.2	0.8	0.9	0.3	0.3	0.5	0.8	0.3	0.0	0.0
Sensitivity / hurt feelings	0.2	0.3	2.2	0.0	0.1	0.0	-0.6	-0.2	-0.0	-0.4	-1.5
Systolic blood pressure, automated reading	0.2	0.5	2.1	-0.6	0.6	0.6	1.5	-0.1	-0.2	0.1	0.8
Medication for hormone replacement therapy	0.2	0.2	0.8	-0.9	-0.4	-0.4	0.3	0.0	0.2	-0.2	-0.4
Supplements: Zinc	0.2	0.3	1.1	-1.0	-0.6	0.2	-0.5	0.4	0.4	0.2	0.0
Diabetes (mother)	0.2	0.3	0.9	-0.6	-0.5	-0.4	0.2	0.5	0.9	-0.3	-0.0
Fed-up feelings	0.2	0.3	0.8	0.9	-0.1	-0.5	-0.4	0.3	0.0	-0.3	-0.9
Relative age voice broke	0.2	0.4	1.3	-0.2	-0.1	-0.6	-0.5	-0.6	-1.1	-0.3	-0.7
Taking other prescription medications	0.2	0.3	1.0	1.0	-0.5	-0.0	0.6	-0.3	-0.7	-0.1	-0.8
Sitting height	0.2	1.5	4.2	1.1	2.0	1.6	-0.4	0.3	0.3	1.1	1.5
Waist circumference	0.2	0.9	3.3	-1.4	0.1	-0.4	0.1	-0.8	-1.8	-0.8	-0.5
Medication: Simvastatin	0.2	0.3	1.0	-0.1	0.3	1.0	0.9	0.5	0.0	0.5	0.3
Impedance of arm (right)	0.2	0.9	1.8	-0.3	-1.3	-0.8	-0.8	-1.2	-0.7	-0.8	-1.0
Hip circumference	0.2	0.9	3.3	-0.5	0.4	-0.4	-1.1	-1.1	-1.8	-0.8	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	1.5	1.1	0.1	0.1	-0.0	1.2	1.1	0.8	0.0
Pulse wave Arterial Stiffness index	0.2	0.3	0.6	0.4	-0.8	0.4	0.8	-0.5	-0.2	0.5	0.4
Breastfed as a baby	0.2	0.3	0.8	-0.1	0.9	0.3	0.8	0.1	0.6	0.3	0.3
Blood clot in the leg (DVT)	0.2	0.3	1.1	0.6	-0.7	-0.3	1.1	0.1	-0.3	0.1	0.7
Medication: Paracetamol	0.2	0.3	0.7	0.5	0.6	0.8	-0.1	0.0	-0.1	0.7	0.7
High blood pressure (siblings)	0.2	0.2	1.1	-1.1	0.3	0.4	0.5	-0.2	-0.4	0.1	-0.2
Wheeze or whistling in the chest in last year	0.2	0.4	1.2	0.1	0.2	-0.3	0.7	0.5	0.8	-0.6	-1.1
Number of children fathered	0.2	0.3	1.2	1.1	0.4	0.3	-0.1	0.1	0.7	0.5	0.2
Medication for pain relief, constipation, heartburn	0.2	0.4	1.1	-0.4	-0.5	-0.3	-0.9	0.3	1.1	-0.5	-0.4
Leg fat mass (right)	0.2	0.9	2.1	-1.4	0.1	-0.9	-0.3	-0.7	-1.4	-1.1	-0.7
Comparative height size at age 10	0.2	0.8	2.3	0.9	0.5	0.8	1.1	1.0	1.5	0.7	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	1.7	0.3	-0.8	-0.5	0.7	-0.7	-1.3	-0.3	-0.5
Miserableness	0.2	0.4	2.2	-0.4	-0.0	-0.5	-1.5	0.2	0.3	-0.1	-0.7
Arm fat-free mass (left)	0.2	0.9	2.6	0.1	1.6	1.2	0.0	0.7	0.5	0.8	1.2
Fractured/broken bones in last 5 years	0.2	0.3	0.7	0.1	-0.8	-0.2	-0.6	0.2	0.8	-0.4	-0.6
Diastolic blood pressure, automated reading	0.2	0.7	1.8	-1.0	0.5	0.1	1.2	-0.4	-1.3	-0.5	0.6
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.9	0.5	-0.9	-0.5	0.9	0.1	-0.2	-0.1	0.6
Impedance of whole body	0.2	0.9	2.0	-0.7	-1.3	-1.4	-0.6	-0.7	-0.5	-0.8	-1.2
Intelligence (Savage-Jansen 2018)	0.1	0.4	1.6	-0.7	-0.1	0.8	-1.3	-0.1	0.1	0.3	0.3
Blood Eosinophil Count	0.1	0.7	2.5	0.2	0.9	0.8	1.6	-0.2	-1.2	0.1	0.3
Heel T-Score	0.1	0.9	3.4	-1.4	0.6	0.3	-1.9	-0.9	0.3	0.1	0.6
BMI	0.1	0.4	1.0	0.5	1.0	0.9	-0.0	0.5	-0.1	0.4	0.9
Systolic Blood Pressure	0.1	0.5	3.5	-0.4	-0.2	0.5	1.9	0.2	0.1	-0.2	-0.0
Cardiovascular Disease	0.1	0.4	1.0	-0.5	-0.5	-0.4	-0.2	-0.4	-0.9	-1.0	-0.6
Impedance of leg (right)	0.1	0.7	2.0	-0.7	-1.2	-1.4	0.2	0.0	0.4	-0.4	-1.2
Age when periods started (menarche)	0.1	0.3	1.0	0.2	-0.1	-0.3	1.0	0.8	-0.6	0.3	0.1
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.2	0.5	-0.3	0.2	-0.1	-0.4	-0.0	-0.3	-0.0
Medication: Atenolol	0.1	0.1	0.4	0.5	-0.1	-0.0	0.2	-0.3	-0.2	-0.3	-0.6
Body mass index (BMI)	0.1	0.4	1.9	-0.8	0.4	-0.2	-0.3	-0.5	-1.4	-0.7	-0.0
Impedance of leg (left)	0.1	0.6	1.5	-0.9	-1.0	-1.2	-0.2	-0.1	0.3	-0.4	-1.2
Hair/balding pattern: Pattern 2	0.1	0.1	0.4	-0.1	-0.2	0.4	-0.6	0.1	0.2	0.0	0.1
Weight	0.1	0.3	0.7	-0.6	0.9	0.1	-0.3	-0.3	-0.8	-0.3	0.1
Trunk fat-free mass	0.1	0.8	2.2	-0.2	1.5	1.2	0.1	0.5	0.6	0.8	1.0
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.5	0.7	-0.0	-0.6	-0.4	-0.1	-0.1	-0.1	0.2
Prospective memory result	0.1	0.1	0.2	-0.5	-0.5	0.3	0.4	-0.1	-0.1	-0.1	-0.0
Trunk predicted mass	0.1	0.7	2.2	-0.2	1.5	1.2	-0.0	0.5	0.5	0.8	0.9
Standing height	0.1	0.8	1.5	0.8	1.2	0.9	0.2	0.9	1.2	1.1	0.6
Exposure to tobacco smoke at home	0.1	0.2	0.7	0.1	0.0	0.0	0.3	0.3	0.8	0.1	-0.6
Forced vital capacity (FVC), Best measure	0.1	0.5	1.5	0.9	0.1	0.1	0.1	1.2	1.1	0.7	-0.6
Angina (self-reported)	0.1	0.1	0.7	-0.2	0.2	0.2	0.8	0.3	-0.3	0.4	0.1
Heart disease (mother)	0.1	0.1	0.3	0.5	-0.4	-0.1	-0.2	0.3	-0.2	-0.0	0.5
Had major operations	0.1	0.1	0.3	-0.5	-0.1	0.1	-0.2	-0.5	0.1	-0.3	-0.2
Hypertension (Self-reported)	0.1	0.4	1.0	-0.5	-0.2	-0.4	-1.0	-0.8	-0.8	-0.7	-0.0
Whole body fat-free mass	0.1	0.5	1.6	-0.0	1.3	0.9	0.1	0.5	0.4	0.5	0.8
Loneliness, isolation	0.1	0.2	0.7	0.8	-0.6	-0.1	0.2	-0.2	0.3	-0.0	0.0
Ever had bowel cancer screening	0.1	0.1	0.2	0.2	-0.5	-0.2	0.1	-0.2	0.3	-0.2	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.1	0.1	0.4	-0.2	-0.0	-0.5	-0.6	0.1	-0.1	-0.1	-0.4
Whole body water mass	0.1	0.4	1.6	-0.1	1.3	0.9	0.0	0.5	0.3	0.5	0.7
Wears glasses or contact lenses	0.1	0.1	0.3	-0.3	0.5	0.3	-0.3	-0.3	0.4	-0.2	0.3
High cholesterol (Self-reported)	0.1	0.1	0.6	0.4	0.0	-0.1	0.8	0.1	-0.3	-0.1	0.1
Medication: Paracetamol	0.1	0.1	0.4	-0.1	-0.4	0.0	-0.0	-0.3	-0.6	0.2	0.3
Arm predicted mass (left)	0.1	0.5	1.7	-0.2	1.3	0.9	-0.3	0.4	0.4	0.5	0.7
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.1	0.1	0.3	0.2	0.1	-0.4	-0.1	-0.0	0.0
Height	0.0	0.3	1.2	0.4	0.3	0.5	0.2	0.2	1.1	0.6	0.5
Lung FVC	0.0	0.1	0.4	-0.7	-0.1	0.0	-0.4	-0.0	0.3	0.0	0.2
Hair Pigment	0.0	1.1	2.0	-0.7	0.8	1.2	1.4	1.1	1.0	1.2	0.8
Tanning	0.0	0.3	1.0	-0.7	0.2	1.0	0.4	0.2	0.2	0.7	0.2
Leg fat-free mass (left)	0.0	0.1	0.6	-0.2	0.8	0.3	-0.2	0.0	-0.3	-0.2	0.3
Leg predicted mass (left)	0.0	0.1	0.7	-0.0	0.8	0.4	-0.2	0.1	-0.2	-0.1	0.4
Arm fat-free mass (right)	0.0	0.2	1.2	-0.3	1.1	0.3	0.1	0.4	0.2	0.1	0.2
Arm predicted mass (right)	0.0	0.1	0.6	-0.4	0.8	0.1	-0.1	0.3	0.1	-0.1	0.1
Chest pain or discomfort	0.0	0.0	0.1	-0.0	0.1	0.0	0.1	0.4	-0.0	0.1	-0.2
Leg fat-free mass (right)	0.0	0.2	0.9	-0.1	1.0	0.5	-0.3	0.1	-0.3	0.0	0.4
Leg predicted mass (right)	0.0	0.2	0.9	-0.1	0.9	0.5	-0.3	0.1	-0.2	0.1	0.4
Basal metabolic rate	0.0	0.2	1.2	-0.3	1.1	0.6	-0.2	0.1	-0.1	0.1	0.5

Hub : Genes

OR2W3

Models

Trait associations