Best TWAS P=6.36e-12 · Best GWAS P=9.11e-12 conditioned to 3.09e-08
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | ACTR2 | 0.07 | 0.04 | lasso | 1 | 0.04 | 3.8e-06 | 5.6 | 5.6 | 2.6e-08 | 0.20 | 0.77 | 0.11 | TRUE |
2 | NTR | Blood | SERTAD2 | 0.04 | 0.02 | lasso | 4 | 0.04 | 9.5e-12 | 6.6 | -6.9 | 6.4e-12 | -0.04 | 0.00 | 1.00 | TRUE |