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chr2:99,468,341-101,731,705

Best TWAS P=6.15e-20 · Best GWAS P=7.1e-26 conditioned to 1.54e-07

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Artery Tibial	AFF3	0.06	0.04	enet	6	0.04	4.3e-04	8.3	-9.1	6.1e-20	0.83	0.57	0.23	TRUE
7	The Cancer Genome Atlas	Brain Lower Grade Glioma	AFF3	0.03	0.01	blup	240	0.02	6.6e-03	-10.4	-9.0	2.3e-19	0.83	0.02	0.90	FALSE
1	CommonMind	Brain Pre-frontal Cortex	AFF3	0.31	0.24	enet	32	0.25	9.2e-31	-5.8	-7.3	2.3e-13	0.65	1.00	0.00	FALSE
6	YFS	Blood	AFF3	0.06	0.04	enet	11	0.06	6.2e-18	-3.2	7.2	4.8e-13	-0.52	1.00	0.00	FALSE
2	GTEx	Adrenal Gland	CHST10	0.18	0.04	lasso	4	0.05	5.6e-03	-2.4	6.0	1.5e-09	-0.45	0.34	0.10	FALSE
4	NTR	Blood	AFF3	0.03	0.01	blup	626	0.01	4.0e-03	5.2	5.6	2.6e-08	-0.46	0.32	0.11	FALSE
5	ROSMAP	Brain Pre-frontal Cortex	AFF3	0.31	0.24	enet	38	0.25	3.5e-32	-5.9	-5.1	2.7e-07	0.55	1.00	0.00	FALSE