[Hub]/) : Traits : Blood Red Count :

chr2:197,134,790-200,117,777

Best TWAS P=1.2e-09 · Best GWAS P=3.66e-10 conditioned to 0.109

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Breast Mammary Tissue SF3B1 0.06 0.06 lasso 4 0.03 6.6e-03 -4.4 -5.2 1.9e-07 0.70 0.17 0.68 FALSE
2 GTEx Breast Mammary Tissue (Female) SF3B1 0.05 -0.01 lasso 3 -0.01 8.1e-01 -4.5 -5.2 2.4e-07 0.75 0.05 0.10 FALSE
3 GTEx Lung RFTN2 0.06 0.08 lasso 8 0.06 2.7e-05 -6.1 -6.1 1.4e-09 0.99 0.03 0.97 FALSE
4 GTEx Skin Sun Exposed Lower leg MARS2 0.04 0.05 enet 8 0.03 1.2e-03 -6.1 6.0 1.6e-09 -0.98 0.04 0.96 FALSE
5 GTEx Spleen RFTN2 0.11 0.03 enet 26 0.05 2.4e-02 -6.2 -6.1 1.2e-09 0.96 0.04 0.70 FALSE
6 GTEx Spleen MARS2 0.12 0.04 lasso 5 0.00 3.4e-01 -6.2 6.1 1.2e-09 -0.94 0.04 0.57 TRUE
7 GTEx Thyroid SF3B1 0.04 0.02 enet 14 0.02 2.0e-02 -5.0 -5.9 3.1e-09 0.83 0.08 0.84 FALSE
8 GTEx Thyroid PLCL1 0.04 0.01 lasso 4 0.00 2.6e-01 -6.0 -5.8 6.5e-09 0.89 0.11 0.73 FALSE
9 GTEx Whole Blood PLCL1 0.08 0.08 enet 15 0.05 4.1e-05 -5.3 -5.2 1.8e-07 0.89 0.35 0.65 FALSE
10 YFS Blood ANKRD44 0.02 0.00 blup 416 0.01 6.3e-04 -2.2 5.2 1.8e-07 -0.46 0.14 0.48 FALSE
11 YFS Blood PLCL1 0.10 0.10 lasso 9 0.14 1.5e-43 -5.6 -5.8 7.4e-09 0.84 0.45 0.55 FALSE
12 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma RFTN2 0.05 0.01 blup 61 0.02 3.1e-02 -4.4 -5.9 3.3e-09 0.81 0.04 0.41 FALSE