[Hub]/) : Traits : Respiratory disease :

chr9:4,934,896-7,345,375

Best TWAS P=2.69e-27 · Best GWAS P=3.84e-64 conditioned to 9.36e-28

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex GLDC 0.24 0.10 lasso 6 0.15 8.5e-18 5.65 7.3 2.8e-13 0.14 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex KIAA1432 0.04 0.00 blup 514 0.03 2.7e-04 -0.47 10.0 2.0e-23 0.24 0.07 0.04 TRUE
3 GTEx Esophagus Muscularis IL33 0.17 0.03 enet 29 0.06 1.7e-04 -5.59 8.4 5.4e-17 0.38 0.07 0.40 FALSE
4 GTEx Skin Sun Exposed Lower leg KIAA1432 0.11 0.04 lasso 5 0.03 9.2e-04 5.55 5.4 7.3e-08 -0.02 0.59 0.02 FALSE
5 GTEx Testis RP11-207C16.4 0.30 0.18 lasso 8 0.17 4.7e-08 5.47 5.3 1.4e-07 -0.10 0.98 0.00 FALSE
6 GTEx Thyroid KIAA1432 0.08 0.04 enet 10 0.04 9.5e-04 5.10 5.1 2.7e-07 0.01 0.58 0.02 FALSE
7 ROSMAP Brain Pre-frontal Cortex RANBP6 0.07 0.01 blup 396 0.02 1.7e-03 1.08 6.9 4.1e-12 -0.03 0.89 0.00 TRUE
8 ROSMAP Brain Pre-frontal Cortex GLDC 0.11 0.00 enet 5 0.01 7.4e-03 14.90 10.8 2.7e-27 0.56 0.04 0.54 TRUE
9 The Cancer Genome Atlas Breast Invasive Carcinoma ERMP1 0.05 0.02 blup 80 0.02 3.3e-04 7.57 -5.8 6.3e-09 0.01 0.04 0.93 FALSE