[Hub]/) : Traits : Respiratory disease : ← →

chr17:42,413,481-43,570,226

Best TWAS P=5.27e-09 · Best GWAS P=1.79e-08 conditioned to 0.0022

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cortex CTD-2020K17.3 0.31 0.17 lasso 10 0.18 1.0e-05 4.9 5.4 8.2e-08 0.36 0.03 0.77 FALSE
2 GTEx Breast Mammary Tissue DCAKD 0.16 0.13 lasso 7 0.13 2.9e-07 5.5 -5.3 9.4e-08 -0.59 0.04 0.96 FALSE
3 GTEx Breast Mammary Tissue (Male) DCAKD 0.36 0.29 lasso 8 0.33 1.4e-08 4.4 -5.7 1.0e-08 -0.58 0.08 0.89 FALSE
4 GTEx Esophagus Gastroesophageal Junction DCAKD 0.42 0.36 lasso 7 0.37 3.8e-14 5.5 -5.2 2.0e-07 -0.58 0.01 0.99 FALSE
5 GTEx Skin Not Sun Exposed Suprapubic DCAKD 0.30 0.21 lasso 6 0.20 5.0e-11 5.5 -5.3 1.1e-07 -0.58 0.01 0.99 FALSE
6 GTEx Whole Blood DCAKD 0.07 0.08 lasso 2 0.06 1.8e-06 4.3 -5.2 1.6e-07 -0.52 0.30 0.68 FALSE
7 The Cancer Genome Atlas Bladder Urothelial Carcinoma LOC644172 0.08 0.00 blup 79 0.04 3.2e-04 -3.8 -5.8 5.3e-09 -0.51 0.02 0.84 TRUE
8 The Cancer Genome Atlas Breast Invasive Carcinoma C17orf46 0.04 0.02 enet 5 0.04 4.1e-08 -3.7 5.4 5.5e-08 0.31 0.03 0.97 FALSE
9 The Cancer Genome Atlas Esophageal Carcinoma LOC644172 0.19 0.12 lasso 3 0.05 8.2e-03 4.8 -5.2 2.3e-07 -0.42 0.02 0.24 FALSE
10 The Cancer Genome Atlas Testicular Germ Cell Tumors MGC57346 0.11 0.12 lasso 2 0.11 1.1e-04 4.4 -5.4 8.4e-08 -0.39 0.05 0.40 FALSE