TWAS hub - C17orf46

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Breast Invasive Carcinoma	0.0427	0.0190	1.1e-07	0.020	0.028	0.037	NA	0.002	4.1e-05	1.8e-06	4.1e-08	NA	1.2e-01
2	TCGA	Cervical Squamous Cell Carcinoma	0.1680	0.0980	9.0e-04	0.051	0.049	0.020	NA	0.042	1.6e-03	1.9e-03	3.3e-02	NA	3.8e-03
3	TCGA	Colon Adenocarcinoma	0.0660	0.0350	2.8e-03	0.001	0.043	0.047	NA	0.024	2.6e-01	1.7e-03	1.0e-03	NA	1.5e-02
4	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0540	0.0310	4.6e-03	0.053	0.047	0.035	NA	0.032	5.7e-04	1.1e-03	4.4e-03	NA	5.9e-03
5	TCGA	Lung Adenocarcinoma	0.0395	0.0227	6.2e-04	0.032	0.024	0.036	NA	0.035	1.0e-04	7.3e-04	3.7e-05	NA	5.9e-05
6	TCGA	Lung Squamous Cell Carcinoma	0.0361	0.0226	4.3e-03	0.005	0.012	0.003	NA	0.001	7.1e-02	1.3e-02	1.3e-01	NA	2.5e-01
7	TCGA	Prostate Adenocarcinoma	0.0459	0.0270	1.2e-03	0.030	0.029	0.028	NA	0.028	4.0e-04	4.8e-04	5.6e-04	NA	5.7e-04
8	TCGA	Rectum Adenocarcinoma	0.4540	0.1950	5.3e-03	-0.012	0.064	0.112	NA	0.017	7.7e-01	1.4e-02	1.4e-03	NA	1.3e-01
9	TCGA	Stomach Adenocarcinoma	0.0430	0.0260	1.0e-02	0.012	0.006	-0.003	NA	0.008	4.4e-02	1.0e-01	6.2e-01	NA	7.8e-02
10	TCGA	Thyroid Carcinoma	0.0680	0.0300	1.5e-06	0.087	0.061	0.066	NA	0.030	8.0e-09	1.4e-06	5.5e-07	NA	5.9e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Allergy	9.7	22.2	37.0	-5.3	-4.7	-6.0	-3.6	-3.8	-3.2	-5.7	-2.8	-6.1	-4.5
Hayfever, allergic rhinitis or eczema	9.3	20.3	32.0	4.3	4.9	5.3	4.1	4.0	3.5	5.3	2.9	5.7	4.3
Allergy or Eczema	8.0	21.0	33.5	4.8	5.3	4.9	4.3	4.1	2.8	5.8	2.8	5.7	4.3
Hair/balding pattern: Pattern 3	7.1	10.6	17.1	3.2	3.3	2.8	3.3	3.5	3.1	4.1	-0.4	3.7	3.5
Alcohol drinker status: Previous	6.6	7.5	10.3	2.6	2.9	2.6	3.1	2.8	2.2	3.1	1.6	3.2	2.8
Respiratory disease	6.4	14.3	29.5	5.4	3.2	5.1	2.5	3.0	3.0	4.4	1.2	4.3	3.6
Alzheimer’s Disease (in father)	6.3	6.8	12.1	-2.8	-2.1	-2.4	-1.3	-3.3	-1.7	-3.3	-2.7	-2.1	-3.5
Hair/balding pattern: Pattern 4	6.3	15.3	24.4	4.1	4.3	2.8	4.7	4.0	2.7	4.9	-1.2	4.7	4.0
Illnesses of father: None of the above (group 1)	4.9	6.0	14.0	2.7	2.1	1.6	2.5	3.7	1.8	2.6	1.6	1.9	3.1
Medication: Co-codamol	4.6	5.3	8.1	2.2	1.9	2.6	1.2	2.4	2.3	2.5	2.3	2.4	2.9
Seen a psychiatrist for nerves, anxiety, tension or depression	4.6	6.0	9.6	3.0	2.1	3.1	1.1	2.0	2.6	3.1	2.0	2.1	2.5
Emphysema/chronic bronchitis	4.6	5.2	7.9	2.8	2.3	2.4	1.7	2.3	2.3	2.3	1.6	2.1	2.6
Systolic Blood Pressure	4.0	19.9	42.0	6.5	3.0	5.1	2.5	4.4	4.0	5.3	-1.6	4.4	5.6
Systolic blood pressure, automated reading	4.0	11.7	22.6	4.8	2.4	4.0	1.8	3.4	2.8	4.3	0.6	3.5	4.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	4.0	4.8	7.1	-2.4	-2.4	-2.5	-2.1	-1.7	-2.1	-2.6	-0.9	-2.7	-1.7
Asthma	3.8	7.4	20.2	4.5	1.8	4.3	1.4	1.5	1.5	2.8	-0.0	3.7	2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.8	4.5	10.9	2.0	2.1	2.0	3.3	2.1	2.3	1.2	-0.3	2.8	1.7
Lupus	3.7	5.6	10.0	2.4	2.4	1.6	2.9	3.2	2.1	2.4	1.1	2.3	2.6
Ovarian Cancer	3.6	4.8	12.2	1.1	2.9	1.2	3.5	2.3	1.8	2.5	-0.6	2.6	1.8
Relative age of first facial hair	3.5	7.1	8.9	-2.9	-2.5	-2.7	-3.0	-2.8	-2.8	-2.9	-0.0	-3.0	-2.7
Unable to work because of sickness or disability	3.5	4.5	7.1	1.8	2.1	2.3	1.5	1.9	2.5	2.7	1.7	1.9	2.5
Asthma (self-reported)	3.4	6.8	19.7	4.4	1.6	4.2	1.2	1.2	1.4	2.5	-0.2	3.6	1.8
Medication: Aspirin	3.3	4.3	7.0	-1.6	-2.1	-1.8	-1.6	-2.2	-2.3	-2.6	-1.8	-1.8	-2.6
Basal cell carcinoma (self-reported)	3.3	3.9	6.5	2.3	2.1	2.4	1.6	1.6	1.6	2.0	1.5	2.5	1.9
Ever had prostate specific antigen (PSA) test	3.0	3.5	6.0	-0.8	-2.1	-1.0	-2.2	-2.4	-2.0	-2.2	-1.1	-1.7	-2.2
Body Mass Index (BMI) (2010)	2.9	3.9	7.1	-2.7	-2.1	-1.6	-2.2	-2.3	-1.0	-2.2	-0.6	-2.1	-2.1
Medication: Ventolin 100micrograms inhaler	2.9	3.7	9.6	3.1	1.1	2.8	1.4	1.2	1.4	2.0	-1.3	2.5	1.3
Commuting to job workplace: Public transport	2.8	3.3	7.0	-2.3	-1.3	-1.3	-0.4	-2.1	-0.7	-2.7	-2.2	-1.1	-2.6
Mouth/teeth dental problems: Bleeding gums	2.7	3.5	5.7	-1.9	-2.0	-2.3	-2.2	-1.8	-2.1	-1.2	-0.8	-2.4	-1.5
Other serious medical condition/disability diagnosed by doctor	2.6	3.4	8.4	2.9	1.4	2.5	1.0	1.7	1.6	1.6	1.5	1.6	1.8
Mouth/teeth dental problems: Loose teeth	2.5	3.0	4.8	1.6	1.8	1.2	1.9	2.1	1.2	2.2	0.3	1.9	2.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.5	2.9	4.3	1.8	1.8	1.4	1.9	2.0	1.3	2.1	-0.4	2.0	1.7
High blood pressure (siblings)	2.4	3.4	7.1	2.6	1.6	1.6	1.5	1.9	0.3	2.7	0.8	2.1	2.1
Osteoporosis (self-reported)	2.4	3.0	8.4	1.3	1.8	2.1	1.2	1.2	1.4	1.3	2.9	1.8	1.4
Medication: Aspirin	2.4	3.1	5.4	-1.6	-1.6	-1.7	-1.2	-1.8	-1.8	-2.3	-1.4	-1.6	-2.2
Hearing difficulty/problems: Yes	2.3	3.5	6.1	-1.7	-2.5	-1.6	-2.3	-1.6	-1.8	-2.0	-0.8	-2.2	-1.8
Bilateral oophorectomy (both ovaries removed)	2.3	2.6	5.2	-1.2	-1.9	-2.3	-1.1	-0.7	-2.2	-1.7	-1.5	-1.8	-1.2
Hayfever/allergic rhinitis (self-reported)	2.3	3.0	5.6	1.8	1.6	2.3	1.6	1.7	1.2	1.8	1.1	2.4	1.5
Knee pain experienced in last month	2.3	3.5	6.1	1.9	1.3	1.9	0.7	2.2	2.1	2.1	1.8	1.4	2.5
Sensitivity / hurt feelings	2.2	3.7	7.2	-2.3	-1.7	-2.1	-1.1	-1.5	-2.2	-2.7	0.5	-2.0	-2.2
Number of live births	2.2	3.2	5.8	-0.9	-2.3	-1.2	-2.4	-1.6	-1.5	-2.1	-0.8	-2.4	-1.5
Illness, injury, bereavement, stress in last 2 years	2.2	2.7	5.4	2.1	1.5	1.9	0.6	1.1	1.2	2.3	1.2	1.8	1.8
Supplements: Fish oil (including cod liver oil)	2.2	2.8	6.4	2.3	1.2	1.4	1.1	2.0	0.7	2.5	0.2	1.6	2.1
Prostate Cancer	2.1	3.0	4.8	-1.3	-2.2	-1.8	-1.7	-1.4	-1.8	-1.9	-1.1	-2.0	-1.7
Blood White Count	2.1	15.3	33.2	-2.7	-5.2	-2.2	-5.8	-3.9	-3.2	-4.5	-1.1	-4.8	-3.4
Blood Red Count	2.0	19.7	36.0	-4.1	-5.3	-1.9	-6.0	-5.0	-4.0	-5.2	1.6	-4.2	-4.9
Mineral and other dietary supplements	2.0	2.7	6.7	-2.6	-1.4	-1.4	-1.3	-1.9	-0.5	-2.1	-0.5	-1.5	-1.9
Illnesses of father: Heart disease	1.9	2.6	4.3	-1.6	-1.9	-0.9	-1.8	-2.1	-1.6	-1.5	-1.4	-1.0	-1.9
Diastolic blood pressure, automated reading	1.9	5.9	11.2	3.3	1.5	3.0	0.9	2.3	2.1	3.4	0.6	2.6	3.0
Average weekly spirits intake	1.8	2.3	4.8	-1.1	-1.5	-1.3	-1.3	-1.9	-1.3	-2.2	-0.9	-1.5	-1.8
Impedance of arm (right)	1.8	8.3	14.3	3.8	2.3	2.3	3.1	3.4	3.0	2.9	-1.7	2.7	3.2
Impedance of arm (left)	1.8	8.3	15.9	4.0	2.2	2.2	3.2	3.5	2.7	2.8	-1.8	2.6	3.2
Breastfed as a baby	1.8	2.3	3.7	-0.9	-1.7	-1.3	-1.9	-1.3	-1.9	-1.5	-0.6	-1.9	-1.4
Eye problems/disorders: Glaucoma	1.8	2.2	4.1	-1.6	-2.0	-1.4	-1.8	-1.4	-1.3	-0.9	-0.8	-1.8	-1.4
Mean Putamen Volume	1.7	1.9	4.1	-1.6	-1.4	-1.6	-1.0	-1.0	-2.0	-1.6	0.2	-1.6	-1.2
Smoking Status	1.7	4.0	7.3	1.5	2.7	1.6	2.7	1.7	1.8	1.8	0.8	2.5	1.9
Forced vital capacity (FVC), Best measure	1.7	6.4	11.2	2.4	2.8	2.4	2.5	2.1	3.4	2.8	-1.1	2.7	2.4
Average weekly beer plus cider intake	1.7	2.4	3.3	1.6	1.6	1.5	1.4	1.6	1.7	1.8	0.1	1.7	1.8
Pack years adult smoking proportion	1.6	2.4	4.8	1.3	1.4	0.7	0.9	2.0	0.7	2.2	2.2	1.1	2.0
Wears glasses or contact lenses	1.6	1.8	3.2	-1.7	-0.9	-1.5	-0.8	-1.6	-1.2	-1.5	-0.1	-1.3	-1.8
Impedance of whole body	1.6	8.4	14.8	3.8	2.4	2.0	3.2	3.4	2.6	3.0	-1.8	2.8	3.2
Age at First Birth	1.5	2.1	4.3	-1.9	-1.3	-1.2	-0.2	-1.3	-0.7	-2.1	-1.8	-0.7	-2.1
Impedance of leg (right)	1.5	7.3	12.0	2.9	2.7	1.4	3.5	3.3	2.2	2.9	-1.4	2.8	3.0
Wheeze or whistling in the chest in last year	1.5	2.7	7.1	2.5	0.9	2.7	0.9	1.3	0.9	1.8	-0.2	2.0	1.5
Crohns Disease (2017)	1.4	3.1	6.1	2.1	1.7	1.8	2.5	1.2	1.6	1.5	-1.1	2.5	0.9
Fed-up feelings	1.4	2.5	4.2	-1.1	-1.8	-1.0	-1.3	-1.8	-1.1	-2.0	-1.9	-1.5	-1.8
Age when periods started (menarche)	1.4	3.3	6.9	-1.8	-2.1	-1.8	-1.1	-1.5	-1.0	-2.6	-1.9	-1.8	-2.0
High blood pressure	1.4	4.0	6.7	2.2	1.6	2.0	1.8	2.3	1.9	2.6	0.0	2.1	2.3
Forced vital capacity (FVC)	1.4	5.5	8.3	2.2	2.6	2.1	2.7	1.8	2.9	2.5	-1.4	2.9	2.0
Length of working week for main job	1.4	1.5	7.2	-2.7	0.4	-2.3	1.0	0.4	-0.8	-0.3	-0.2	-0.7	-0.3
Number of self-reported non-cancer illnesses	1.4	2.4	9.2	3.0	0.4	2.2	0.9	1.4	0.9	0.7	-1.4	1.5	1.1
Ever taken oral contraceptive pill	1.4	1.6	3.8	0.6	1.3	1.5	0.4	0.7	1.7	1.2	2.0	1.4	1.2
Coronary Artery Disease (CAD)	1.3	1.6	4.2	0.0	-1.0	-1.3	-0.6	-1.5	-1.2	-2.0	-1.0	-0.9	-1.7
Waist Hip Ratio (WHR)	1.3	5.7	8.7	-3.0	-2.5	-2.1	-2.6	-2.5	-2.7	-2.7	-0.3	-2.1	-2.2
Diverticular disease/diverticulitis (self-reported)	1.3	1.5	4.1	2.0	0.9	1.2	0.9	1.1	0.4	1.7	-0.5	1.3	1.3
Chronic bronchitis/emphysema (father)	1.3	1.5	4.6	1.2	0.9	1.9	0.5	0.7	2.1	0.9	-0.2	1.1	1.2
Tense / ‘highly strung’	1.3	2.1	3.1	1.2	1.3	1.6	1.7	1.6	1.8	1.1	1.1	1.6	1.4
Birth weight of first child	1.3	2.3	6.5	0.5	1.5	1.6	1.3	1.4	2.6	1.2	1.8	1.1	1.3
Medication: Allopurinol	1.3	1.7	2.8	1.2	1.5	0.7	1.1	1.6	1.4	1.6	1.0	0.9	1.7
Hypertension (Self-reported)	1.3	3.7	5.8	2.3	1.5	2.1	1.7	2.1	1.7	2.4	-0.2	2.1	2.2
Handedness (chirality/laterality): Left-handed	1.3	1.5	3.8	1.9	0.9	1.5	0.8	0.4	1.0	1.2	-1.2	1.7	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.7	4.2	1.8	1.4	1.8	1.1	1.5	2.0	2.1	-1.1	1.7	1.8
Age started oral contraceptive pill	1.3	1.7	4.3	-0.8	-1.2	-0.3	-1.8	-2.1	-1.4	-1.3	0.5	-1.0	-1.5
Vascular/heart problems diagnosed by doctor	1.3	3.5	5.8	-2.1	-1.5	-1.9	-1.7	-2.2	-1.7	-2.4	0.1	-2.0	-2.2
Lung FVC	1.2	6.2	11.2	2.3	2.6	2.2	2.5	2.2	3.3	2.9	-1.3	2.5	2.3
Multivitamins +/- minerals	1.2	1.5	5.1	1.4	0.9	0.5	1.5	2.3	0.1	1.0	1.3	0.7	1.4
Number of children fathered	1.2	1.4	3.8	-0.4	-1.6	-0.3	-1.9	-1.4	-0.6	-1.5	-0.2	-1.1	-1.2
Pulse wave peak to peak time	1.2	1.5	3.9	2.0	0.5	1.0	0.3	1.5	0.6	1.9	0.2	0.5	1.7
Long-standing illness, disability or infirmity	1.2	1.8	6.5	2.0	0.4	2.5	0.3	0.4	1.9	1.0	-0.5	1.1	0.9
Qualifications: nursing, teaching	1.2	1.9	3.7	-0.8	-1.3	-1.1	-0.8	-1.5	-1.5	-1.5	-1.9	-1.1	-1.9
Pack years of smoking	1.2	1.8	3.7	1.4	1.1	0.6	0.7	1.7	0.6	1.8	1.9	0.8	1.7
Ulcerative Colitis	1.1	1.5	3.5	1.0	1.4	0.5	1.9	1.5	1.3	1.0	-0.3	1.4	1.3
Number of treatments/medications taken	1.1	2.0	8.6	2.9	0.3	1.8	0.3	1.2	0.8	1.1	-1.1	1.0	1.4
Vitamin and mineral supplements	1.1	1.5	3.8	-1.9	-1.0	-0.7	-0.8	-1.8	0.1	-1.3	-1.4	-0.7	-1.5
Maternal smoking around birth	1.1	1.6	3.5	1.8	-0.0	1.5	0.1	1.5	1.1	1.3	-0.6	1.1	1.9
Nervous feelings	1.1	2.1	4.4	0.9	1.2	1.6	1.6	1.5	1.4	1.1	2.1	1.5	1.4
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.6	4.0	0.7	1.3	1.3	1.2	1.3	1.3	1.0	2.0	1.3	1.1
Hearing difficulty/problems with background noise	1.1	1.7	6.1	-2.5	-1.7	-0.6	-1.2	-1.0	-0.5	-1.3	0.3	-1.0	-1.3
Forced expiratory volume in 1-second (FEV1)	1.1	3.6	6.6	1.4	2.2	1.4	2.0	1.4	2.6	2.2	-1.4	2.0	1.8
Prospective memory result	1.1	1.3	3.1	1.2	0.5	0.8	0.1	1.7	0.4	1.3	1.8	0.3	1.7
Pulse wave Arterial Stiffness index	1.1	1.3	3.6	-1.8	-0.4	-0.8	-0.1	-1.4	-0.4	-1.9	-0.3	-0.3	-1.7
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	3.9	-2.0	-0.5	-1.0	-0.2	-1.5	-0.7	-1.2	-0.6	-0.5	-1.6
Qualifications: College or University degree	1.1	3.4	15.4	-0.5	2.9	0.5	3.9	0.8	1.2	1.0	-0.4	2.6	0.0
Neck or shoulder pain in last month	1.1	1.6	3.9	1.4	1.1	1.0	0.6	1.7	0.8	2.0	0.7	1.2	1.6
Average weekly champagne plus white wine intake	1.1	1.5	3.4	0.7	1.9	0.6	1.7	1.1	0.6	1.4	0.3	1.8	0.9
Guilty feelings	1.1	1.6	4.2	0.4	1.6	1.0	1.4	1.1	1.2	1.0	2.0	1.4	0.8
Financial situation satisfaction	1.1	1.4	2.9	1.7	1.1	1.6	1.0	0.7	1.3	1.3	-0.1	1.2	1.1
Major Depression (MDD)	1.0	1.2	3.2	0.0	0.6	1.8	0.3	0.0	1.3	1.4	1.0	1.0	1.8
Crohns Disease (2012)	1.0	1.6	3.8	0.0	1.4	1.3	1.7	1.3	0.7	1.6	-0.6	2.0	1.1
LDL Cholesterol	1.0	1.6	4.4	0.5	1.7	0.6	2.1	1.3	0.6	1.0	0.8	1.9	0.8
Impedance of leg (left)	1.0	4.7	7.6	2.5	2.0	1.0	2.7	2.8	1.8	2.2	-1.5	2.1	2.5
Pain all over the body in last month	1.0	1.1	2.4	1.2	0.9	1.5	0.5	0.9	0.7	1.3	0.9	1.0	1.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.2	7.1	1.3	2.1	1.4	1.8	1.4	2.7	2.0	-1.5	1.7	1.7
Exposure to tobacco smoke outside home	1.0	1.3	3.0	-0.4	-1.6	-0.9	-1.4	-0.9	-0.7	-1.1	-1.3	-1.7	-0.9
Medication: Gliclazide	1.0	1.1	3.1	0.4	0.8	1.3	0.9	1.0	1.8	0.8	0.6	1.3	1.1
Smoking status: Current	1.0	1.6	6.7	0.6	1.8	0.6	2.6	1.0	0.5	0.8	0.1	1.8	0.5
Mother’s age at death	1.0	1.3	2.9	-1.2	-0.5	-0.8	-1.0	-1.6	-1.7	-0.7	1.0	-0.7	-1.4
Heart attack/myocardial infarction (self-reported)	1.0	1.3	3.1	-1.1	-1.0	-1.3	-0.3	-1.0	-1.1	-1.1	-1.8	-0.8	-1.2
Irritable Bowel Disease (IBD)	0.9	2.2	5.1	1.6	1.5	1.4	2.2	0.6	1.5	1.0	-1.3	2.2	0.6
Blood Platelet Count	0.9	9.9	26.3	-2.2	-4.0	-3.9	-3.0	-1.3	-5.1	-2.8	-0.7	-3.7	-2.0
Ever had hysterectomy (womb removed)	0.9	1.0	2.3	-0.2	-1.4	-0.4	-1.4	-0.8	-0.5	-1.5	-0.5	-1.1	-0.9
Medication: Metformin	0.9	1.3	3.1	-1.4	-0.7	-0.2	-0.8	-1.8	0.7	-1.7	-0.8	-0.8	-1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.3	3.7	1.3	0.4	1.9	0.4	0.7	1.7	1.0	0.7	1.0	1.0
Mouth/teeth dental problems	0.9	1.4	3.9	1.0	1.5	1.4	1.7	-0.0	1.0	0.6	-0.6	2.0	0.1
Medication: Simvastatin	0.9	1.4	2.4	-1.1	-1.3	-0.9	-1.4	-1.6	-0.6	-1.2	-1.3	-1.0	-1.2
Illnesses of siblings	0.9	1.2	3.6	-1.5	-0.9	-1.0	0.0	-0.8	0.2	-1.9	-1.2	-0.9	-1.4
Ever smoked	0.9	1.6	3.4	0.8	1.9	0.6	1.6	1.5	1.3	1.4	0.7	0.7	1.3
Irritability	0.9	1.5	3.1	-1.0	-1.1	-1.0	-0.7	-1.5	-1.5	-1.8	-0.7	-0.6	-1.6
Bipolar Disorder (2018)	0.8	1.2	2.9	-1.7	-0.3	-0.8	-0.1	-1.3	-1.1	-1.5	0.6	-0.5	-1.7
Primary Biliary Cirrhosis	0.8	1.1	2.6	0.8	0.9	0.6	1.6	1.3	1.2	0.9	-1.1	1.0	0.9
Type 2 Diabetes (T2D) (2012)	0.8	0.9	1.7	1.1	0.7	1.2	0.8	0.8	1.3	0.9	-0.1	0.8	1.0
Cardiovascular Disease	0.8	2.8	3.7	1.9	0.9	1.7	1.6	1.7	1.6	1.7	-1.7	1.9	1.7
Hypothyroidism (self reported)	0.8	1.8	4.2	-0.8	-0.7	-1.3	-0.4	-1.7	-1.3	-2.0	-1.0	-1.1	-2.0
Relative age voice broke	0.8	1.3	3.8	-0.8	-1.4	-0.3	-1.9	-0.6	-0.6	-0.8	1.7	-1.2	-0.5
Taking other prescription medications	0.8	1.3	3.1	1.8	0.8	1.2	1.2	0.7	0.3	1.1	-0.9	1.5	0.9
Heart attack	0.8	1.0	2.5	-0.8	-0.9	-1.0	-0.3	-1.0	-1.2	-0.9	-1.6	-0.7	-1.2
Medication: Lansoprazole	0.8	0.9	2.2	1.5	0.3	0.9	-0.1	0.9	0.4	1.4	-1.1	0.7	1.1
Number of full brothers	0.8	1.0	3.4	-1.9	-0.6	-1.1	-1.2	-0.5	-0.2	-0.5	1.1	-1.4	-0.1
Worry too long after embarrassment	0.8	1.3	3.4	-1.8	-0.8	-0.8	-0.3	-1.4	-0.4	-1.7	0.3	-0.7	-1.5
Medication: Blood pressure	0.8	1.4	3.3	1.1	0.9	1.3	1.1	1.2	1.8	1.0	-0.3	1.1	1.3
Pulse rate, automated reading	0.8	2.7	5.4	1.1	1.9	2.0	1.7	1.1	1.4	2.0	1.1	2.3	1.1
Overall health rating	0.8	1.8	3.7	1.5	0.6	1.3	1.0	1.7	0.6	1.7	-0.6	1.6	1.9
Family relationship satisfaction	0.8	1.0	2.4	1.0	1.1	1.0	1.6	1.1	0.2	1.0	0.3	1.3	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	2.1	-0.4	-1.0	-0.3	-0.8	-1.2	-0.0	-1.2	-1.4	-0.6	-1.2
Tinnitus: Yes, now most or all of the time	0.8	1.0	7.5	-0.1	-0.1	0.2	-0.4	0.9	0.3	0.6	2.7	-0.3	0.8
Commuting to job workplace: Cycle	0.8	1.0	2.5	-0.7	-0.5	-1.1	-0.4	-0.9	-0.2	-1.3	-1.6	-1.2	-1.2
Blood Eosinophil Count	0.7	5.4	25.6	-0.3	-1.9	-1.2	-1.6	-2.4	-0.3	-2.5	-5.1	-1.8	-2.4
Trunk fat percentage	0.7	2.7	5.4	2.3	0.7	2.0	0.3	1.6	1.5	2.1	0.7	1.2	2.3
Past tobacco smoking	0.7	1.3	2.6	-0.8	-1.6	-0.4	-1.3	-1.4	-1.3	-1.3	-0.2	-0.5	-1.4
Glaucoma (self-reported)	0.7	0.8	2.2	-0.9	-1.5	-0.3	-1.1	-0.8	-0.2	-0.8	-0.3	-1.2	-0.9
Medication for pain relief, constipation, heartburn	0.7	1.1	2.8	-0.7	1.3	-0.0	0.7	1.0	1.5	1.2	1.7	0.3	0.9
Had major operations	0.7	0.8	2.3	-1.3	-0.1	-1.5	0.6	-0.1	-1.0	-1.1	-0.6	-0.6	-0.8
Breast cancer (self-reported)	0.7	0.8	3.4	-0.8	0.1	-1.9	0.8	-0.3	-1.6	-0.7	-0.3	-0.2	-0.6
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	2.5	1.3	0.9	0.7	0.7	1.1	-0.3	1.6	0.1	1.1	0.8
Pain experienced in last month	0.7	1.1	2.3	-1.5	-0.3	-1.3	-0.3	-1.4	-0.4	-1.2	-0.7	-1.2	-1.3
Ulcerative Colitis (UC)	0.6	1.0	2.2	1.1	1.1	0.8	1.5	0.5	1.1	0.7	-0.8	1.4	0.7
Heel T-Score	0.6	5.1	10.6	3.2	1.4	2.3	1.6	1.7	1.8	2.8	-2.7	2.2	2.2
Hand grip strength (left)	0.6	1.7	6.7	0.4	1.6	1.3	1.2	0.7	2.6	0.9	0.4	1.3	0.9
Frequency of depressed mood in last 2 weeks	0.6	0.8	2.3	1.0	0.7	1.5	0.9	0.6	1.5	0.3	0.2	0.9	0.4
Current tobacco smoking	0.6	0.9	4.7	0.3	1.4	0.2	2.2	0.7	0.1	0.4	0.1	1.4	0.2
Average weekly fortified wine intake	0.6	0.7	2.3	1.5	0.8	1.3	0.4	0.6	0.6	0.9	0.4	0.8	0.7
Supplements: Glucosamine	0.6	0.8	1.5	1.2	1.2	0.5	0.6	1.0	0.2	1.0	0.8	0.7	1.2
Medication: Levothyroxine sodium	0.6	1.0	2.7	-0.5	-0.7	-1.0	-0.6	-1.1	-1.4	-1.6	-0.1	-0.9	-1.3
Had menopause	0.6	0.7	2.7	-0.3	-0.5	0.3	-1.1	-1.6	-0.5	-0.7	0.5	-0.1	-1.3
Had other major operations	0.6	0.7	1.7	0.8	0.8	-0.4	1.2	1.3	-0.6	0.7	1.1	0.2	0.7
Trunk fat-free mass	0.6	3.6	7.1	-2.7	-1.3	-1.2	-1.8	-2.3	-1.4	-2.2	1.3	-1.7	-2.4
Medication: Cholesterol lowering	0.6	0.9	1.8	-1.0	-1.1	-1.0	-0.6	-0.8	-0.1	-1.1	-1.3	-1.2	-0.9
Lung cancer (father)	0.6	0.7	1.1	0.7	-1.0	-0.4	-1.0	0.9	-1.0	0.5	0.3	-0.9	0.8
Trunk predicted mass	0.6	3.2	6.6	-2.6	-1.1	-1.1	-1.7	-2.2	-1.3	-2.0	1.4	-1.5	-2.2
Blood clot in the leg (DVT)	0.6	0.8	2.0	1.1	0.8	1.0	1.0	0.9	-0.0	0.8	0.7	1.4	0.7
Gout (self-reported)	0.6	0.9	1.6	0.7	1.2	0.2	1.2	0.9	1.1	1.3	-0.1	0.6	1.1
Arm fat-free mass (right)	0.6	3.1	6.2	-2.5	-1.2	-0.9	-1.8	-2.1	-1.2	-1.8	1.8	-1.5	-2.0
Medication: Ibuprofen	0.6	0.7	2.0	0.6	-0.9	0.7	-1.1	-1.0	0.1	-1.4	-0.4	-0.4	-0.8
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.6	-0.8	-0.0	-1.4	0.0	0.4	-1.6	0.6	1.2	-0.1	0.3
Eye problems/disorders: Cataract	0.6	0.7	1.4	1.2	0.7	1.0	0.4	1.0	0.7	0.4	0.9	0.8	0.8
Number of operations (self-reported)	0.6	0.8	2.8	-0.8	0.2	-1.7	1.1	0.3	-1.1	-1.2	-0.5	-0.7	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.6	0.7	1.6	1.0	0.8	0.7	1.0	1.0	-0.3	0.8	0.8	1.3	0.6
Depression (Nagel 2018)	0.5	0.8	2.7	1.0	0.5	1.7	0.6	0.4	1.1	0.7	0.3	1.2	0.6
Schizophrenia vs Biploar Disorder	0.5	0.6	1.8	1.4	-0.1	0.8	-0.3	0.5	0.7	1.1	-0.7	0.2	1.0
Worry (Nagel 2018)	0.5	1.0	4.2	0.1	1.1	0.5	1.3	1.0	0.7	0.3	2.0	0.7	0.6
Alzheimer’s Disease (including proxy)	0.5	0.8	2.4	-1.2	-0.6	-1.2	0.2	-0.4	-0.1	-1.6	-0.7	-0.8	-1.0
Diabetes (father)	0.5	0.6	2.4	-1.6	-0.2	-0.9	0.2	-0.9	-0.1	-0.8	-0.1	-0.2	-1.0
Hand grip strength (right)	0.5	1.3	5.5	0.4	1.2	1.2	1.0	0.9	2.3	0.9	0.2	1.0	0.8
Number of incorrect matches in round	0.5	0.8	2.8	1.2	-0.1	0.5	-0.1	1.2	0.0	0.6	1.7	0.3	1.3
Alcohol usually taken with meals	0.5	0.9	2.8	-0.8	-0.4	-1.1	0.1	-0.8	-1.7	-0.9	-0.7	-0.5	-1.3
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.1	0.2	-0.5	0.4	-1.2	-1.0	-0.3	-0.6	1.4	-0.7	-0.6
Time employed in main current job	0.5	0.5	1.6	0.6	0.9	0.8	0.6	0.3	0.2	1.3	0.1	1.1	0.4
Hypothyroidism/myxoedema (self-reported)	0.5	1.0	2.7	-0.3	-0.7	-0.9	-0.2	-1.0	-1.6	-1.4	-0.3	-0.7	-1.6
Medication: Amlodipine	0.5	0.7	1.5	0.8	0.6	0.5	0.8	1.2	0.9	1.0	0.2	0.4	1.1
Body fat percentage	0.5	2.1	4.6	1.9	0.5	1.8	-0.1	1.4	1.3	1.9	1.0	1.0	2.1
Leg fat percentage (right)	0.5	1.6	3.8	1.2	0.7	1.4	0.0	1.2	1.0	1.9	1.3	1.1	1.9
Arm predicted mass (right)	0.5	2.4	4.7	-2.2	-0.8	-0.5	-1.6	-1.9	-1.0	-1.5	2.1	-1.1	-1.8
Comparative height size at age 10	0.5	2.5	5.5	1.8	1.7	1.2	2.3	2.0	1.8	0.9	0.1	1.4	1.4
Illnesses of siblings: Diabetes	0.5	0.6	2.0	-0.3	-1.0	-0.7	-1.2	0.5	-0.2	-0.0	0.8	-1.4	0.4
Medication: Blood pressure	0.5	0.9	3.0	0.9	0.8	0.3	0.9	1.1	-0.1	1.7	-0.9	0.8	1.2
Ever depressed for a whole week	0.5	0.6	2.0	-0.2	1.1	0.1	1.2	0.6	0.5	0.4	1.4	0.4	0.4
Depressed Affect (Nagel 2018)	0.4	0.8	1.3	-1.1	-1.1	-0.5	-0.8	-1.0	-0.8	-1.1	-0.5	-0.8	-1.1
Breast Cancer	0.4	1.0	2.1	-1.2	-0.9	-0.4	-0.9	-1.2	-0.6	-1.4	0.4	-0.7	-1.4
Triglycerides	0.4	0.6	1.5	-1.2	0.6	-0.9	1.0	-0.7	-0.5	-0.4	-0.5	0.5	-0.8
Ever used hormone-replacement therapy (HRT)	0.4	0.5	2.0	1.4	0.2	0.5	0.1	0.8	-0.2	0.3	1.3	0.3	0.7
Hair/balding pattern: Pattern 2	0.4	0.5	3.3	-0.6	0.1	0.1	-0.0	0.4	0.5	0.2	1.8	-0.6	0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	3.4	-0.9	-0.9	-0.2	-0.5	-1.1	0.6	-1.3	-1.8	-0.8	-1.0
Qualifications: None of the above	0.4	0.8	3.0	1.7	-0.1	0.7	-0.3	1.0	0.1	1.0	0.1	0.6	1.4
Financial difficulties in last 2 years	0.4	0.5	2.2	0.0	0.7	-0.2	0.7	1.2	0.3	0.0	1.5	-0.2	0.7
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	2.3	1.5	0.1	1.0	0.2	1.1	0.8	0.6	-0.8	0.1	1.0
Pulse rate	0.4	0.6	3.8	0.7	-0.1	0.8	0.2	-0.5	-0.1	0.3	-1.9	0.9	-0.2
Qualifications: A levels/AS levels or equivalent	0.4	0.8	2.0	-1.4	0.4	-1.0	0.9	-0.8	-0.2	-0.8	-1.0	-0.1	-1.4
Depression (self-reported)	0.4	0.5	2.1	0.2	0.2	1.0	-0.4	-0.1	1.5	-0.2	1.1	-0.1	0.0
Health satisfaction	0.4	0.5	0.9	-0.9	-0.7	-0.2	-0.8	-0.9	-0.5	-0.6	-0.6	-0.5	-0.8
Medication: Seretide 50 evohaler	0.4	0.5	1.5	1.0	-0.2	1.2	-0.2	-0.6	0.4	-0.2	-0.9	0.7	-0.2
Heart disease (mother)	0.4	0.5	1.7	0.8	-0.6	1.3	-0.9	0.0	0.9	0.2	0.1	0.0	0.4
Number of full sisters	0.4	0.4	1.1	0.8	-0.4	-0.4	-0.2	1.1	-1.0	0.4	-0.3	-0.2	1.0
Suffer from ‘nerves’	0.4	0.6	2.0	-0.3	0.4	0.4	0.7	1.0	1.2	0.1	1.4	0.1	0.7
Smoking status: Previous	0.4	0.6	1.8	0.5	0.8	0.2	0.3	0.9	1.3	0.9	-0.3	-0.1	1.3
Whole body fat-free mass	0.4	2.2	4.2	-2.0	-1.0	-0.7	-1.6	-1.8	-0.9	-1.6	1.6	-1.3	-1.7
Loneliness, isolation	0.4	0.5	1.3	-0.0	0.7	0.6	0.2	0.7	0.5	1.1	1.2	0.6	0.8
Whole body water mass	0.4	2.1	4.0	-2.0	-0.9	-0.6	-1.5	-1.8	-0.8	-1.6	1.6	-1.2	-1.7
Medication: Paracetamol	0.4	0.6	2.1	1.0	-1.0	0.5	-0.8	-0.7	-0.5	-0.6	-1.5	-0.2	-0.2
Medication: Lisinopril	0.4	0.5	2.4	0.9	0.2	-0.2	0.9	0.4	-0.6	0.2	-1.6	0.3	0.1
Medication: Atorvastatin	0.4	0.5	1.4	-0.4	-0.7	-0.2	-0.7	-0.6	0.2	-0.6	-1.1	-1.2	-0.5
Leg fat percentage (left)	0.4	1.3	3.0	1.0	0.3	1.3	-0.4	1.0	0.8	1.7	1.3	0.7	1.7
Arm fat-free mass (left)	0.4	2.0	4.3	-2.1	-0.8	-0.6	-1.6	-1.7	-0.9	-1.3	2.0	-1.1	-1.5
Heart disease (siblings)	0.4	0.5	1.9	-0.1	-0.4	0.4	-1.2	-1.0	-0.5	0.1	1.4	-0.2	-0.5
Arm predicted mass (left)	0.4	2.1	5.0	-2.2	-0.7	-0.7	-1.4	-1.7	-1.1	-1.2	2.0	-1.0	-1.6
Reaction Time	0.3	0.5	2.8	-0.7	0.8	-0.7	1.7	0.6	0.6	-0.1	-0.4	-0.0	-0.0
Fasting Glucose	0.3	0.4	1.1	0.3	1.1	-0.2	0.9	0.5	0.2	0.6	0.7	0.4	0.7
HDL Cholesterol	0.3	0.5	1.6	-0.1	-1.3	0.2	-1.2	-0.3	-0.0	-0.7	0.3	-1.3	-0.3
BMI	0.3	2.0	5.4	-1.5	-1.9	-0.4	-2.3	-1.8	-0.8	-1.1	-0.1	-1.4	-1.1
Type 2 Diabetes (T2D) (2018)	0.3	0.6	1.6	1.0	0.7	1.0	0.6	0.6	1.3	0.2	-0.2	0.8	0.6
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	1.7	-1.3	0.2	-1.0	0.3	0.0	-0.4	0.6	0.2	-0.4	0.1
Angina	0.3	0.4	1.1	0.6	-0.5	0.5	-0.9	0.2	0.4	0.5	-1.0	-0.3	0.9
Medication for hormone replacement therapy	0.3	0.4	0.8	-0.0	-0.5	-0.9	-0.4	-0.3	-0.7	-0.5	-0.9	-0.8	-0.2
Qualifications: CSEs or equivalent	0.3	0.4	1.9	-1.4	0.3	-0.9	0.2	0.5	-0.5	0.5	0.5	-0.2	0.2
Sitting height	0.3	2.0	3.3	1.4	1.8	1.7	1.4	0.7	1.8	1.8	-0.2	1.8	0.7
High blood pressure (mother)	0.3	0.4	1.9	0.0	0.7	-0.2	1.4	0.6	0.1	0.4	-1.0	0.5	0.2
Trunk fat mass	0.3	1.4	2.8	1.6	0.4	1.7	-0.1	0.9	1.1	1.4	1.0	0.9	1.5
Hip circumference	0.3	1.3	2.7	1.4	0.7	1.6	0.2	0.9	0.8	1.3	1.5	1.0	1.3
Father’s age at death	0.3	0.3	1.3	0.1	-0.2	-0.5	-0.2	-0.7	-1.1	-0.5	-0.5	-0.2	-0.9
Noisy workplace	0.3	0.3	1.5	0.2	-0.6	-0.2	-0.8	-0.3	-1.2	0.3	0.6	-0.3	0.1
Exposure to tobacco smoke at home	0.3	0.3	1.1	0.1	-0.2	-0.2	-0.5	-0.1	1.0	-0.4	-0.9	-1.0	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.6	0.1	-0.6	0.6	-1.3	-0.8	0.7	-0.2	-0.1	-0.5	-0.5
Peak expiratory flow (PEF)	0.3	0.7	3.7	0.2	0.3	0.4	-0.3	-1.1	1.0	-0.1	-1.9	0.4	-0.5
Pulse wave reflection index	0.3	0.4	1.6	-1.2	0.3	-0.7	0.2	0.6	0.4	-0.2	0.9	-0.1	0.2
Loud music exposure frequency	0.3	0.4	0.8	0.7	0.4	0.9	-0.4	-0.2	0.8	0.9	0.8	0.1	0.4
Chronic bronchitis/emphysema (mother)	0.3	0.3	1.4	0.4	0.4	1.2	0.1	0.1	0.9	0.3	0.1	0.6	0.4
Shortness of breath walking on level ground	0.3	0.4	1.3	1.1	-0.4	1.1	-0.5	0.4	0.0	0.1	0.3	0.5	0.5
Eye problems/disorders: None of the above	0.3	0.3	1.0	-0.6	-0.3	-0.5	-0.2	-0.7	-0.2	-1.0	-0.3	-0.4	-0.8
Angina (self-reported)	0.3	0.4	1.6	0.3	-0.7	0.2	-1.1	-0.1	0.1	0.2	-1.3	-0.5	0.5
Migraine (self-reported)	0.3	0.4	1.5	-0.1	-0.7	0.4	-0.1	-0.8	-0.4	-1.2	-0.3	0.2	-0.8
Chest pain or discomfort	0.3	0.4	1.6	0.4	-0.1	0.9	-0.1	0.2	0.4	0.8	-1.3	0.6	0.4
Leg pain on walking	0.3	0.4	1.0	-0.5	-0.7	0.2	-1.0	-0.7	-0.9	-0.7	0.7	-0.3	-0.6
Diabetes diagnosed by doctor	0.3	0.5	2.7	0.6	-0.1	1.1	-0.3	0.0	1.7	-0.2	-0.6	0.1	0.4
Medication for cholesterol	0.3	0.4	1.2	-0.4	0.7	0.5	0.9	-0.1	0.8	-0.3	1.1	0.7	-0.3
Leg predicted mass (right)	0.3	1.4	2.7	-1.2	-1.0	-0.1	-1.6	-1.3	-0.4	-1.3	1.6	-1.2	-1.2
Miserableness	0.3	0.5	1.3	0.7	0.5	0.8	0.5	0.9	1.1	0.5	0.7	0.3	0.8
Fractured/broken bones in last 5 years	0.3	0.4	1.3	0.4	-0.4	-0.2	-1.1	-0.3	-0.1	-1.0	0.7	-0.9	-0.3
Bipolar Disorder or Schizophrenia	0.2	0.6	1.5	-1.0	0.4	-0.6	0.8	-0.7	-0.8	-1.1	0.1	-0.1	-1.2
Neuroticism (Nagel 2018)	0.2	0.4	1.0	-0.9	-0.0	-0.6	0.5	-0.2	-0.7	-1.0	0.7	-0.3	-0.7
Alzheimer’s Disease (in mother)	0.2	0.2	0.6	-0.2	-0.3	-0.8	0.2	0.6	-0.2	-0.8	0.1	-0.6	0.0
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.5	-0.1	0.3	0.5	0.1	-0.9	1.1	-0.6	-1.2	0.1	-1.0
Rheumatoid Arthritis	0.2	0.3	0.7	0.1	-0.5	0.4	-0.7	-0.9	-0.3	-0.6	-0.4	-0.1	-0.7
Schizophrenia (2014)	0.2	0.5	2.6	0.1	0.3	-0.6	1.0	0.0	-0.6	-0.3	-1.6	0.3	-0.5
Lung FEV1/FVC ratio	0.2	1.1	2.0	-1.4	-0.5	-1.4	-1.2	-1.2	-0.9	-0.4	-0.8	-1.2	-0.9
Neuroticism	0.2	0.5	2.6	-0.4	0.4	0.3	0.8	0.4	0.4	-0.8	1.6	0.2	-0.1
Supplements: Zinc	0.2	0.2	0.7	0.3	-0.0	0.1	0.3	-0.5	-0.8	-0.5	-0.5	0.0	-0.6
Severe depression (siblings)	0.2	0.3	0.8	0.1	-0.2	0.2	-0.5	-0.9	-0.7	-0.3	0.1	-0.1	-0.8
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	2.5	-0.1	-0.5	0.3	-0.2	-0.5	1.0	-0.7	-1.6	-0.4	-0.5
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	1.0	0.5	0.3	0.3	0.4	0.3	0.6	-0.0	-1.0	0.2	0.3
Serious illness, injury or assault to yourself	0.2	0.2	1.0	-1.0	0.1	-0.3	0.1	-0.7	-0.0	-0.4	-0.2	-0.0	-0.8
Medication: Atenolol	0.2	0.2	0.7	0.3	-0.0	0.7	-0.3	0.3	0.7	0.8	-0.3	-0.0	0.7
Body mass index (BMI)	0.2	1.0	3.8	-0.8	-1.0	0.1	-1.9	-0.9	-0.6	-0.1	1.6	-0.8	-0.2
Waist circumference	0.2	0.6	2.2	-0.6	-0.8	0.3	-1.5	-0.7	-0.5	-0.2	1.5	-0.4	-0.0
Diabetes (self-reported)	0.2	0.3	1.5	0.1	-0.4	0.3	-0.6	-0.4	0.7	-0.6	-1.2	-0.2	-0.1
Medication: Ramipril	0.2	0.3	1.0	0.7	-0.1	0.5	-0.8	0.0	0.1	1.0	0.6	-0.2	0.6
Fluid intelligence score	0.2	0.4	1.2	-0.1	0.4	-0.1	0.4	-0.7	0.6	-0.8	-1.1	-0.2	-0.9
Arm fat percentage (right)	0.2	0.8	1.8	1.0	-0.1	1.2	-0.7	0.6	0.7	1.2	0.9	0.3	1.4
Falls in the last year	0.2	0.2	1.1	0.1	-0.2	0.3	-0.9	-0.2	0.0	0.2	1.1	-0.4	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	1.0	-0.3	-0.1	0.7	-0.3	-0.5	1.0	-0.3	-0.3	-0.0	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.9	0.6	-0.2	0.9	-0.5	-0.4	0.4	-0.6	0.0	0.1	-0.0
Illnesses of mother	0.2	0.2	0.5	-0.5	-0.5	-0.4	-0.7	-0.4	-0.5	-0.4	0.2	-0.5	-0.1
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.7	-0.3	-0.6	0.3	-0.2	-0.3	0.2	-0.6	-0.8	-0.2	-0.2
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	1.2	-0.3	1.1	0.2	0.9	0.2	0.5	0.1	0.9	0.8	-0.2
Medication: Paracetamol	0.2	0.3	0.6	0.7	-0.7	0.5	-0.6	-0.5	-0.8	-0.3	-0.4	-0.0	0.0
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.2	-0.2	0.0	-0.4	-0.6	-0.4	-1.1	-0.2	0.8	-0.2	-0.3
Birth weight	0.2	0.5	1.7	0.2	1.0	0.6	0.7	0.3	0.5	0.4	1.3	0.9	0.2
Comparative body size at age 10	0.2	0.5	1.8	0.2	-0.8	-0.2	-1.2	-0.2	-0.4	-0.6	0.9	-1.3	-0.3
Medication: Omeprazole	0.2	0.2	0.7	0.2	-0.0	-0.2	0.3	0.4	-0.7	0.4	-0.9	0.2	-0.1
Whole body fat mass	0.2	0.8	1.9	1.0	0.1	1.4	-0.6	0.4	0.7	1.2	1.2	0.5	1.2
Leg fat mass (right)	0.2	0.8	2.4	0.6	0.3	1.2	-0.5	0.4	0.7	1.2	1.5	0.6	1.2
Supplements: Vitamin C	0.2	0.3	1.0	0.4	0.2	-0.6	-0.5	0.1	-1.0	0.3	0.4	-0.5	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.5	1.5	-0.1	0.9	0.7	1.1	0.3	1.2	0.3	0.1	0.7	0.2
Leg fat-free mass (right)	0.2	1.3	3.0	-1.1	-0.9	-0.0	-1.6	-1.3	-0.4	-1.2	1.7	-1.1	-1.1
Arm fat percentage (left)	0.2	1.0	2.1	1.1	-0.0	1.3	-0.7	0.6	0.8	1.3	1.1	0.4	1.4
Average weekly red wine intake	0.2	0.3	1.1	0.1	0.5	0.2	1.0	0.6	0.8	0.0	-0.5	0.3	0.4
Ever had bowel cancer screening	0.2	0.2	0.6	0.6	-0.5	0.4	-0.7	-0.1	0.2	-0.8	0.6	-0.4	-0.1
Friendships satisfaction	0.2	0.3	0.9	-0.3	-0.1	-0.1	-0.0	-1.0	-0.1	-0.5	-0.8	-0.2	-0.9
Commuting to job workplace: Walk	0.2	0.3	0.7	0.7	-0.2	0.7	-0.8	-0.5	0.3	-0.1	-0.6	-0.4	-0.0
Back pain experienced in last month	0.2	0.3	1.0	1.0	-0.1	1.0	-0.2	0.3	0.5	0.3	-0.3	0.6	0.5
Osteoarthritis (self-reported)	0.2	0.3	0.9	0.7	-0.4	-0.7	-0.1	0.8	-0.9	-0.0	-0.3	-0.1	0.7
Hearing aid user	0.2	0.3	0.8	-0.3	0.0	-0.7	0.4	-0.2	-0.4	-0.9	-0.8	-0.4	-0.5
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.9	-0.1	-0.7	-0.7	-0.5	0.2	-0.5	0.1	-0.2	-0.9	0.0
Illnesses of father: High blood pressure	0.2	0.3	0.7	-0.3	0.8	-0.1	0.5	-0.8	-0.4	0.6	0.1	0.6	-0.5
Basal metabolic rate	0.2	1.4	3.1	-1.6	-0.7	-0.3	-1.3	-1.3	-0.6	-1.2	1.8	-0.9	-1.2
Risk taking	0.2	0.2	1.2	0.2	-0.1	-0.7	-0.0	-0.1	-1.1	-0.1	-0.4	-0.6	-0.4
Myopia	0.2	0.3	1.0	-0.4	0.1	0.0	0.6	-0.0	1.0	-0.6	-0.8	-0.2	-0.2
Cholesterol lowering medication	0.2	0.3	0.9	0.8	-0.4	0.9	-0.8	-0.6	-0.1	0.3	-0.7	0.2	-0.1
Supplements: Calcium	0.2	0.2	0.7	0.5	0.7	0.1	0.4	-0.5	-0.8	0.0	-0.3	0.6	-0.4
Leg fat mass (left)	0.2	0.7	2.6	0.4	-0.1	1.1	-0.9	0.1	0.5	0.9	1.6	0.2	0.9
Intelligence (Savage-Jansen 2018)	0.1	0.4	1.1	0.2	0.9	0.1	1.0	-0.1	0.6	-0.2	-1.0	0.6	-0.6
Schizophrenia (2018)	0.1	0.2	1.4	0.1	0.7	-0.2	1.2	0.2	-0.2	-0.1	-0.3	0.2	-0.2
Bipolar Disorder (2011)	0.1	0.1	0.3	0.0	-0.1	-0.4	-0.3	-0.5	-0.6	-0.4	0.1	-0.3	-0.4
HbA1C	0.1	0.2	0.9	-1.0	-0.2	-0.1	0.2	-0.0	0.1	-0.6	-0.2	0.3	-0.3
Neuroticism (2016)	0.1	0.2	0.9	-0.1	0.1	0.5	-0.3	0.2	0.6	-0.3	1.0	-0.4	0.3
Chronotype (morning person)	0.1	0.3	1.0	-0.9	-0.2	-1.0	0.1	0.5	-0.4	-0.1	0.2	-0.4	0.1
Tanning	0.1	1.0	2.5	-1.1	-0.9	-1.0	-0.8	-1.2	-0.5	-0.9	-1.6	-0.9	-0.8
Diabetes (mother)	0.1	0.1	0.2	-0.1	0.4	-0.3	0.4	0.1	-0.0	0.3	0.1	0.2	0.3
Leg fat-free mass (left)	0.1	0.8	3.2	-1.0	-0.5	0.2	-1.0	-0.9	-0.1	-0.7	1.8	-0.6	-0.7
Townsend deprivation index at recruitment	0.1	0.1	0.3	0.4	-0.1	-0.1	0.0	0.4	0.5	-0.5	-0.0	-0.5	0.4
Stomach or abdominal pain in last month	0.1	0.1	0.4	0.2	-0.1	0.4	-0.2	-0.0	0.6	0.1	-0.2	-0.3	0.1
Leg predicted mass (left)	0.1	0.7	3.2	-0.9	-0.4	0.2	-1.0	-0.8	-0.1	-0.6	1.8	-0.5	-0.6
Neuroticism score	0.1	0.3	1.0	-1.0	0.1	-0.2	0.4	-0.2	0.3	-0.8	0.9	-0.1	-0.5
Weight	0.1	0.5	2.0	-0.4	-0.6	0.4	-1.2	-0.7	-0.2	-0.3	1.4	-0.5	-0.3
Alcohol intake versus 10 years previously	0.1	0.1	0.5	0.1	0.1	-0.3	0.7	0.3	0.0	-0.2	-0.3	0.1	-0.0
Worrier / anxious feelings	0.1	0.2	0.4	-0.3	0.3	-0.1	0.7	0.1	0.3	-0.6	0.6	-0.1	-0.3
Happiness	0.1	0.1	0.3	0.2	-0.2	0.3	0.1	-0.3	-0.1	-0.4	-0.5	-0.1	-0.3
Mouth/teeth dental problems: Dentures	0.1	0.2	0.5	0.0	-0.6	0.0	-0.4	0.7	0.6	0.0	0.4	-0.5	0.5
Arm fat mass (right)	0.1	0.4	1.4	0.1	-0.5	0.7	-1.2	-0.3	0.2	0.4	1.1	-0.2	0.4
Standing height	0.1	0.8	1.9	1.2	1.0	0.9	1.4	0.5	1.2	-0.2	-0.5	0.8	-0.0
Headache pain in last month	0.1	0.2	0.8	-0.2	-0.2	0.6	0.3	0.3	-0.0	-0.2	0.5	0.9	-0.2
Age at first live birth	0.1	0.1	0.7	0.1	0.1	0.3	0.0	-0.4	0.1	0.0	-0.9	0.4	-0.4
Mean time to correctly identify matches	0.1	0.3	0.5	-0.6	-0.0	-0.7	0.5	-0.1	0.4	-0.3	-0.7	-0.7	-0.5
Alcohol intake frequency.	0.1	0.2	0.3	0.3	0.1	0.5	0.4	0.4	-0.4	0.5	0.4	0.5	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.2	-0.4	-0.3	-0.5	-0.3	-0.0	-0.2	-0.0	-0.2	-0.4	0.1
Mood swings	0.1	0.1	0.4	0.2	-0.6	0.4	-0.3	0.1	0.2	-0.6	-0.2	-0.2	0.2
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	1.0	0.0	-0.3	0.2	-0.3	0.3	-0.2	-0.7	1.0	-0.3	0.0
Arm fat mass (left)	0.1	0.4	1.6	0.2	-0.4	0.9	-1.2	-0.4	0.3	0.4	1.3	-0.1	0.4
High cholesterol (Self-reported)	0.1	0.2	1.0	-0.2	-0.3	0.3	-0.4	-0.6	0.4	-0.1	-1.0	-0.2	-0.3
Medication: Bendroflumethiazide	0.1	0.1	0.8	0.2	0.2	0.2	0.0	0.3	-0.0	0.9	-0.1	0.2	0.4
Alcohol drinker status: Never	0.1	0.2	0.8	0.1	0.2	0.6	-0.3	0.1	0.1	0.6	0.9	0.1	0.2
Height	0.0	0.8	2.1	0.5	0.3	0.5	1.0	-0.4	1.5	-1.3	-1.0	0.1	-1.2
Hair Pigment	0.0	0.7	1.8	0.5	0.9	0.2	1.3	1.1	0.6	0.8	-1.2	0.9	0.3
Age at last live birth	0.0	0.1	0.3	0.5	0.3	0.2	0.3	0.3	-0.0	0.2	-0.0	0.3	0.1

Hub : Genes

C17orf46

Models

Trait associations