Best TWAS P=7.54e-13 · Best GWAS P=9.86e-15 conditioned to 0.00218
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Pancreas | RP5-1029K10.2 | 0.20 | 0.00 | enet | 49 | 0.06 | 0.00229 | 6.2 | 5.5 | 3.9e-08 | 0.34 | 0.06 | 0.42 | FALSE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | ZNF652 | 0.09 | 0.01 | enet | 12 | 0.05 | 0.00055 | 6.8 | -5.6 | 2.0e-08 | -0.55 | 0.02 | 0.46 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ZNF652 | 0.03 | 0.03 | enet | 5 | 0.03 | 0.00026 | 6.2 | -6.8 | 1.4e-11 | -0.90 | 0.02 | 0.95 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ZNF652 | 0.06 | 0.03 | lasso | 4 | 0.02 | 0.00165 | 6.2 | -5.7 | 1.4e-08 | -0.76 | 0.20 | 0.56 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZNF652 | 0.05 | 0.02 | blup | 55 | 0.02 | 0.00249 | 7.7 | -7.2 | 7.5e-13 | -0.87 | 0.01 | 0.97 | TRUE |