TWAS hub - TRPT1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2120	0.0500	7.1e-13	0.038	0.130	0.127	0.121	0.122	1.9e-05	1.5e-15	3.6e-15	1.5e-14	1.4e-14
2	GTEx	Adipose Visceral Omentum	0.1560	0.0620	6.3e-04	0.046	NA	0.040	NA	0.042	2.1e-03	NA	3.9e-03	NA	3.0e-03
3	GTEx	Artery Tibial	0.0600	0.0280	7.2e-03	0.072	NA	0.048	NA	0.062	2.6e-06	NA	1.2e-04	NA	1.3e-05
4	GTEx	Brain Frontal Cortex BA9	0.2354	0.1008	6.3e-03	0.221	NA	0.120	NA	0.192	1.6e-06	NA	4.6e-04	NA	8.2e-06
5	GTEx	Cells Transformed fibroblasts	0.1890	0.0700	3.3e-03	0.090	NA	0.019	NA	0.063	2.9e-07	NA	1.3e-02	NA	1.8e-05
6	GTEx	Colon Transverse	0.2370	0.0800	4.5e-06	0.205	NA	0.161	NA	0.170	4.5e-10	NA	4.3e-08	NA	1.6e-08
7	GTEx	Esophagus Mucosa	0.1610	0.0500	6.4e-05	0.062	NA	0.070	NA	0.082	5.5e-05	NA	2.1e-05	NA	3.8e-06
8	GTEx	Esophagus Muscularis	0.2010	0.0530	2.8e-07	0.115	NA	0.149	NA	0.139	1.8e-07	NA	2.4e-09	NA	8.4e-09
9	GTEx	Heart Atrial Appendage	0.1860	0.0520	2.9e-06	0.143	NA	0.128	NA	0.154	5.8e-07	NA	2.3e-06	NA	2.0e-07
10	GTEx	Heart Left Ventricle	0.2386	0.0587	6.2e-08	0.145	NA	0.142	NA	0.174	4.0e-08	NA	5.4e-08	NA	1.3e-09
11	GTEx	Muscle Skeletal	0.2447	0.0487	0.0e+00	0.263	NA	0.255	NA	0.270	1.0e-25	NA	7.0e-25	NA	1.6e-26
12	GTEx	Nerve Tibial	0.1422	0.0484	3.4e-05	0.025	NA	0.054	NA	0.067	6.2e-03	NA	1.1e-04	NA	1.8e-05
13	GTEx	Pancreas	0.1030	0.0460	8.7e-03	0.050	NA	-0.004	NA	0.014	3.5e-03	NA	5.4e-01	NA	7.8e-02
14	GTEx	Stomach	0.1420	0.0620	5.0e-03	0.054	NA	0.054	NA	0.072	1.4e-03	NA	1.4e-03	NA	2.5e-04
15	NTR	Blood	0.0203	0.0106	2.6e-03	0.006	0.008	0.007	0.009	0.009	4.1e-03	8.1e-04	2.1e-03	5.9e-04	4.1e-04
16	ROSMAP	Brain Pre-frontal Cortex	0.1695	0.0407	1.1e-11	0.139	0.092	0.145	0.139	0.154	1.8e-17	7.9e-12	3.1e-18	1.9e-17	3.0e-19
17	TCGA	Breast Invasive Carcinoma	0.0358	0.0161	8.6e-04	0.016	0.014	0.018	NA	0.018	2.8e-04	4.8e-04	1.2e-04	NA	1.2e-04
18	TCGA	Kidney Renal Clear Cell Carcinoma	0.0515	0.0282	2.9e-03	0.023	0.013	0.005	NA	0.007	1.1e-03	1.0e-02	8.1e-02	NA	4.3e-02
19	TCGA	Brain Lower Grade Glioma	0.0853	0.0337	3.1e-05	0.053	0.051	0.061	NA	0.059	1.2e-06	1.7e-06	1.7e-07	NA	2.9e-07
20	TCGA	Lung Adenocarcinoma	0.0518	0.0266	4.2e-03	0.008	0.008	0.022	NA	0.002	3.5e-02	3.6e-02	1.1e-03	NA	1.7e-01
21	TCGA	Prostate Adenocarcinoma	0.1796	0.0573	9.5e-10	0.097	0.093	0.093	NA	0.093	2.7e-10	6.5e-10	6.0e-10	NA	5.7e-10
22	TCGA	Stomach Adenocarcinoma	0.0730	0.0420	7.4e-03	0.017	0.007	-0.002	NA	0.003	2.0e-02	9.8e-02	5.4e-01	NA	1.9e-01
23	TCGA	Thyroid Carcinoma	0.1470	0.0630	5.2e-06	0.062	0.062	0.092	NA	0.082	1.1e-06	1.2e-06	2.8e-09	NA	2.3e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23
Reaction Time	5.2	9.9	29.0	2.4	4.7	-0.4	-0.5	-1.6	4.9	-1.6	4.4	5.0	4.9	5.4	3.4	4.4	4.1	-1.7	1.7	-0.3	1.9	0.6	-2.5	1.0	1.1	-2.4
Mean time to correctly identify matches	5.0	9.5	27.2	2.2	4.8	0.2	0.1	-1.0	4.6	-1.4	4.6	4.8	4.9	5.2	3.3	4.3	3.9	-1.9	2.0	-0.1	1.9	0.9	-2.5	1.2	1.5	-2.2
Mineral and other dietary supplements	5.0	6.7	13.0	-2.3	-3.6	-2.4	-2.5	-0.9	-2.7	-2.1	-3.4	-3.3	-3.5	-2.7	-3.0	-1.9	-3.1	0.2	-3.2	-2.8	-2.8	-2.9	-0.9	-3.4	-0.8	-0.1
Blood Platelet Count	4.5	52.1	132.2	-7.9	-10.2	0.4	0.5	4.7	-10.2	4.1	-10.4	-10.7	-9.4	-11.1	-7.8	-11.5	-6.8	7.3	-2.5	0.3	-6.2	-2.4	3.8	-3.0	-7.2	6.2
Ever had prostate specific antigen (PSA) test	4.5	5.2	10.2	2.2	2.3	2.8	2.8	2.2	0.6	1.8	2.6	1.6	1.5	0.7	3.0	2.0	1.3	-1.6	3.0	2.8	3.2	3.0	1.7	2.9	2.2	2.2
Commuting to job workplace: Cycle	4.3	5.2	11.3	1.3	2.7	1.9	1.9	1.8	3.0	2.2	2.7	3.0	3.4	2.4	1.9	1.3	3.4	0.4	3.3	2.5	2.3	2.2	-0.6	3.0	-0.7	-0.5
Supplements: Fish oil (including cod liver oil)	4.0	5.2	10.6	2.8	2.6	2.6	2.6	1.7	1.9	2.4	2.7	2.3	2.6	1.6	2.5	1.1	2.5	0.3	3.1	2.9	2.2	2.9	0.8	3.3	0.5	0.5
Supplements: Calcium	4.0	4.4	11.1	1.7	2.6	1.9	2.0	0.7	0.9	0.7	3.1	1.9	1.7	1.3	2.8	2.8	1.2	-1.9	2.3	2.0	3.3	2.2	2.0	2.2	2.7	1.2
Alcohol drinker status: Never	3.9	4.7	9.1	-2.8	-2.6	-2.3	-2.1	-1.1	-1.6	-1.1	-2.5	-2.4	-2.3	-1.8	-2.4	-2.6	-1.9	2.1	-2.3	-1.9	-2.6	-2.4	-0.7	-2.6	-3.0	-0.5
Number of incorrect matches in round	3.8	6.3	13.2	3.0	3.4	0.7	0.7	0.7	3.1	0.4	3.5	3.6	3.2	3.0	3.6	3.3	3.3	-2.5	2.1	1.2	2.8	1.6	1.0	1.9	2.0	-1.1
Number of live births	3.8	5.4	16.9	-1.1	-3.0	1.4	1.6	2.5	-4.0	1.3	-1.9	-3.6	-3.3	-4.1	-1.6	-2.4	-2.2	0.6	0.5	1.3	0.3	0.7	3.4	0.1	1.1	3.3
Nervous feelings	3.7	6.9	14.1	3.7	2.6	2.9	2.8	1.7	1.2	2.2	2.8	2.2	2.2	1.2	2.5	2.0	2.7	-2.0	3.5	3.5	3.7	3.5	1.5	3.7	2.3	1.0
Leg pain on walking	3.7	4.6	8.8	-2.6	-2.0	-2.6	-2.5	-1.9	-1.1	-1.8	-2.5	-1.6	-1.7	-1.0	-3.0	-1.6	-1.7	1.1	-2.6	-2.6	-2.7	-2.8	-1.8	-2.8	-2.0	-1.5
Chronic bronchitis/emphysema (father)	3.6	4.3	9.1	-2.3	-2.1	-2.2	-2.1	-1.5	-1.7	-1.9	-2.4	-2.0	-2.3	-1.5	-2.2	-1.7	-2.2	1.0	-2.8	-2.5	-2.4	-2.8	-0.2	-3.0	-1.5	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	3.6	4.7	10.8	3.0	2.5	1.9	1.8	1.1	2.3	1.4	2.4	2.5	2.5	2.0	2.4	1.8	1.9	-1.2	2.4	2.3	2.6	2.5	-0.2	3.3	2.1	-1.0
Hand grip strength (right)	3.5	9.6	22.0	-2.1	-2.9	-3.9	-3.8	-2.7	-2.0	-3.9	-3.4	-2.9	-3.7	-1.9	-2.1	-1.0	-4.6	-0.7	-4.7	-4.2	-3.3	-4.0	-1.1	-4.1	0.7	-1.6
Arm fat mass (right)	3.5	14.5	37.3	-3.8	-6.1	-1.5	-1.2	0.6	-5.3	1.1	-5.9	-5.3	-5.2	-5.2	-5.6	-5.4	-3.5	2.0	-3.1	-1.5	-3.8	-2.5	1.4	-3.1	-2.8	1.4
Qualifications: NVQ or HND or HNC or equivalent	3.5	4.2	9.2	-2.6	-2.7	-2.2	-2.2	-1.9	-1.0	-3.0	-2.3	-2.1	-2.1	-1.0	-2.4	-0.3	-2.7	-1.4	-2.6	-2.5	-1.5	-2.1	-1.8	-2.5	-0.3	0.2
Arm fat mass (left)	3.5	14.3	36.7	-3.6	-6.1	-1.5	-1.3	0.5	-5.2	1.0	-5.9	-5.3	-5.1	-5.1	-5.6	-5.4	-3.5	2.1	-3.2	-1.7	-3.9	-2.6	1.2	-3.2	-2.7	1.3
Arm fat percentage (right)	3.4	13.6	36.0	-3.6	-6.0	-1.5	-1.2	0.4	-5.2	0.9	-5.7	-5.2	-5.1	-5.0	-5.4	-5.0	-3.4	1.7	-3.1	-1.6	-3.5	-2.4	1.4	-3.2	-2.7	1.7
Loud music exposure frequency	3.4	3.8	10.0	-0.9	-1.4	-2.6	-2.6	-2.6	-1.7	-2.4	-2.0	-1.3	-2.2	-0.9	-1.1	-0.3	-2.6	-0.8	-3.2	-2.6	-2.0	-2.3	-0.7	-2.8	0.7	-0.7
Pulse rate, automated reading	3.4	11.1	29.3	-2.8	-5.2	-1.1	-0.9	-0.2	-3.7	0.3	-5.0	-4.6	-3.8	-4.0	-5.4	-4.9	-4.0	4.4	-2.0	-1.1	-3.8	-2.0	-0.9	-1.8	-3.3	0.8
Supplements: Zinc	3.3	3.6	9.5	1.5	3.1	1.1	1.1	0.4	2.6	0.1	2.9	2.4	2.5	2.4	2.9	2.3	1.5	-1.7	2.0	1.1	2.1	1.7	-0.5	1.8	0.3	0.4
Alcohol intake versus 10 years previously	3.2	4.8	16.7	3.5	2.3	1.1	0.7	-0.3	2.0	-0.5	2.7	2.3	2.0	2.0	2.2	3.4	2.2	-2.8	1.4	1.0	3.1	1.4	1.5	1.7	4.1	-0.4
Tense / ‘highly strung’	3.2	5.2	13.5	2.3	2.5	2.2	2.2	1.6	1.6	1.7	2.6	2.7	2.5	1.8	2.0	2.5	2.8	-2.0	2.7	2.5	3.7	2.3	0.9	3.0	2.1	0.1
Arm fat percentage (left)	3.1	12.5	32.9	-3.3	-5.7	-1.4	-1.2	0.3	-4.9	0.9	-5.4	-4.9	-4.8	-4.8	-5.3	-4.8	-3.1	1.7	-3.0	-1.7	-3.6	-2.5	1.1	-3.2	-2.5	1.5
Worry (Nagel 2018)	3.0	6.3	13.3	3.6	3.5	2.1	2.0	1.2	2.3	1.5	3.2	3.3	2.9	2.5	2.8	2.6	3.0	-2.3	2.4	2.1	3.1	2.1	0.3	2.7	2.4	-0.9
Trunk fat percentage	2.9	11.6	29.3	-3.0	-5.4	-0.9	-0.6	0.6	-5.1	1.3	-5.1	-5.0	-4.8	-5.0	-4.8	-4.7	-3.3	1.5	-2.7	-1.1	-3.2	-1.9	1.7	-2.6	-2.2	2.0
Multivitamins +/- minerals	2.9	3.7	9.2	1.8	1.8	2.2	2.1	1.1	1.3	1.2	2.2	1.5	1.6	1.0	2.1	1.8	1.9	-1.9	2.4	2.3	3.0	2.5	1.2	2.5	1.5	1.6
Whole body fat mass	2.9	12.0	30.1	-3.4	-5.5	-1.4	-1.1	0.4	-4.9	0.9	-5.3	-4.9	-4.8	-4.8	-5.0	-4.7	-3.3	1.5	-3.1	-1.5	-3.5	-2.4	1.4	-3.0	-2.1	1.2
Bipolar Disorder (2011)	2.8	2.7	6.6	1.5	2.4	0.9	0.9	0.6	1.7	0.4	2.3	2.3	2.0	1.8	2.6	2.5	1.9	-2.5	1.1	0.0	2.1	0.9	0.0	1.0	0.0	0.0
Length of working week for main job	2.8	3.1	5.8	-2.4	-1.5	-1.6	-1.6	-2.4	-1.0	-0.6	-1.9	-1.2	-1.3	-0.7	-2.1	-1.8	-1.5	2.1	-2.4	-1.9	-2.3	-2.2	-1.6	-2.0	-1.9	-0.7
Body fat percentage	2.8	11.1	29.1	-3.0	-5.4	-0.9	-0.6	0.6	-5.0	1.2	-5.0	-4.9	-4.8	-4.9	-4.7	-4.5	-3.2	1.4	-2.6	-1.2	-3.1	-1.9	1.7	-2.7	-1.9	1.9
Neuroticism (2016)	2.6	3.7	10.0	2.3	1.4	2.0	1.9	2.4	-0.0	1.6	1.3	1.3	1.0	0.2	1.9	1.1	1.2	-0.8	2.9	3.2	3.0	3.0	1.4	3.1	2.0	0.0
Trunk fat mass	2.6	11.4	28.9	-3.1	-5.4	-1.1	-0.8	0.5	-5.0	1.1	-5.2	-4.8	-4.7	-4.8	-4.9	-4.7	-3.2	1.5	-2.8	-1.3	-3.3	-2.1	1.4	-2.7	-2.1	1.4
Primary Biliary Cirrhosis	2.5	3.5	7.0	-2.6	-2.2	-2.0	-1.7	-2.2	-1.9	-2.6	-1.5	-2.1	-2.2	-1.5	-2.6	0.2	-2.2	-0.5	-2.1	-2.1	-0.3	-2.2	-0.7	-2.4	-0.2	1.3
BMI	2.5	14.5	37.1	-4.8	-5.8	-1.3	-1.1	0.7	-4.5	1.4	-5.7	-5.0	-4.3	-4.5	-6.1	-5.8	-3.0	3.4	-3.0	-1.9	-4.4	-2.8	-0.3	-3.2	-3.7	0.7
Depression (self-reported)	2.5	3.0	6.9	1.8	0.3	2.4	2.3	1.7	-0.4	1.8	0.9	0.2	0.1	-0.6	1.3	0.8	0.3	-0.9	2.0	2.6	2.4	2.6	2.2	2.6	2.1	1.9
Illnesses of father: High blood pressure	2.5	3.1	8.6	2.5	2.0	1.0	0.9	0.7	2.9	-0.3	2.6	2.2	2.7	2.6	1.6	2.0	2.1	-0.7	1.7	0.4	1.5	0.9	-1.9	1.5	1.1	-0.8
Hip circumference	2.4	10.5	28.6	-3.6	-4.6	-1.6	-1.2	0.3	-4.2	1.8	-5.2	-3.8	-3.8	-4.0	-5.0	-5.3	-1.6	2.4	-2.9	-1.3	-3.4	-2.6	1.1	-2.9	-3.0	-0.2
Leg fat mass (right)	2.4	9.3	23.7	-3.0	-4.9	-1.3	-1.0	0.3	-4.4	0.7	-4.7	-4.3	-4.3	-4.2	-4.5	-4.0	-3.0	0.9	-2.8	-1.5	-2.9	-2.2	1.2	-2.7	-1.3	0.9
Leg fat mass (left)	2.4	9.4	24.5	-2.9	-5.0	-1.1	-0.9	0.5	-4.5	0.8	-4.7	-4.4	-4.3	-4.3	-4.6	-4.0	-3.0	0.8	-2.7	-1.4	-2.8	-2.0	1.3	-2.6	-1.4	1.1
Body mass index (BMI)	2.3	9.9	27.4	-2.9	-5.2	-0.8	-0.6	0.9	-4.6	1.5	-4.9	-4.5	-4.2	-4.5	-4.9	-4.7	-2.6	1.8	-2.2	-0.9	-2.8	-1.9	1.6	-2.3	-1.9	1.6
Medication: Simvastatin	2.3	3.4	11.9	-0.6	-2.7	-0.7	-0.7	-0.6	-2.2	-1.8	-2.0	-2.7	-2.1	-1.9	-3.5	-0.8	-3.1	0.2	-1.5	-1.9	-2.0	-1.7	-1.7	-1.9	0.7	0.6
Neuroticism	2.2	5.2	12.6	3.4	2.9	1.5	1.5	1.0	1.5	0.7	3.0	2.8	2.1	2.1	2.4	3.3	2.5	-2.9	1.8	1.5	3.6	1.5	0.6	1.9	3.4	-0.1
Supplements: Glucosamine	2.2	2.8	6.1	1.0	1.8	2.2	2.2	0.9	0.4	2.3	1.6	1.5	1.5	0.6	2.1	0.3	1.7	0.2	2.0	2.5	1.9	2.1	2.2	2.3	0.9	0.6
Weight	2.2	10.9	26.7	-3.3	-5.2	-1.4	-1.1	0.5	-4.5	0.9	-5.1	-4.6	-4.5	-4.5	-4.8	-4.8	-3.1	1.9	-2.8	-1.5	-3.6	-2.4	1.0	-2.8	-2.0	0.6
Breastfed as a baby	2.2	2.8	7.0	2.6	1.2	2.2	2.3	2.6	0.3	1.9	1.1	0.9	1.2	0.5	1.3	0.1	0.5	0.0	2.3	2.4	0.9	2.6	0.8	2.5	0.9	1.8
Chest pain or discomfort	2.2	3.1	8.4	-1.5	-2.7	0.3	0.3	0.9	-2.8	0.6	-2.4	-2.7	-2.7	-2.8	-2.0	-2.2	-2.9	1.1	-1.0	0.2	-1.1	-0.4	1.4	-0.5	0.1	1.3
Age at First Birth	2.1	3.0	8.3	1.7	1.5	2.2	2.1	1.5	1.6	1.7	1.8	1.3	2.0	1.0	1.2	0.3	1.9	1.1	2.8	2.5	1.7	2.4	0.1	2.9	0.3	0.3
Vitamin and mineral supplements	2.1	2.8	8.4	-1.3	-2.0	-1.6	-1.6	0.1	-0.9	-0.4	-2.1	-1.7	-1.4	-1.3	-1.8	-2.6	-1.1	2.9	-1.5	-1.4	-2.9	-1.8	-0.6	-1.5	-1.6	-1.5
Leg fat percentage (right)	2.1	7.6	20.0	-2.8	-4.5	-1.0	-0.7	0.4	-4.0	0.7	-4.1	-4.1	-3.9	-3.9	-4.1	-3.6	-2.6	0.9	-2.3	-1.2	-2.5	-1.7	1.3	-2.3	-1.2	1.4
Medication: Allopurinol	2.1	2.8	10.8	2.3	-1.1	-1.4	-1.6	-1.6	-0.5	-3.3	-0.8	-0.8	-1.0	-0.0	-1.5	1.3	-1.5	-1.6	-1.7	-2.3	-0.5	-1.9	-2.4	-1.9	2.4	-0.9
Allergy or Eczema	2.0	5.2	14.2	2.8	0.1	3.4	3.4	2.9	-1.3	2.8	0.7	-0.3	0.1	-1.2	1.9	-0.4	-0.3	0.1	2.8	3.4	0.9	3.8	2.7	3.0	1.5	3.5
Hayfever, allergic rhinitis or eczema	2.0	4.3	10.6	2.7	-0.0	3.1	3.0	3.2	-1.0	2.9	0.5	-0.2	0.2	-1.0	1.6	-0.7	0.4	0.4	2.5	3.2	0.9	3.3	2.6	2.8	1.0	2.5
Had menopause	2.0	2.6	9.1	-0.5	-1.4	0.5	0.6	1.0	-3.0	0.9	-1.8	-2.0	-2.6	-2.7	-0.7	-1.7	-2.6	0.5	-0.7	0.7	-0.8	0.1	2.8	-0.2	1.0	1.5
Pulse rate	2.0	3.4	10.0	-1.3	-2.9	0.1	0.3	0.7	-2.2	1.2	-2.9	-2.8	-2.0	-2.7	-3.2	-3.0	-1.1	2.8	-0.2	0.2	-1.2	-0.6	0.1	-0.2	-1.5	0.8
Birth weight	2.0	4.4	11.4	-2.1	-2.3	-1.4	-1.2	-0.1	-3.4	-0.1	-3.1	-2.5	-3.4	-2.9	-1.7	-2.2	-3.0	0.8	-2.5	-1.1	-1.5	-1.9	2.0	-2.3	-0.9	1.1
Risk taking	2.0	2.9	6.4	1.5	2.5	1.3	1.2	1.0	2.0	1.4	2.3	2.2	1.8	1.6	2.5	1.2	1.5	-0.3	1.7	1.9	2.3	2.0	0.4	2.4	0.0	0.1
Hand grip strength (left)	1.9	5.1	13.0	-1.0	-2.3	-2.3	-2.1	-1.5	-2.6	-2.5	-2.4	-2.7	-3.6	-2.4	-1.0	-0.2	-3.5	-2.1	-3.1	-2.4	-1.3	-2.3	0.9	-2.9	2.0	0.6
Ever used hormone-replacement therapy (HRT)	1.9	2.4	6.6	0.4	-1.1	1.7	1.8	1.0	-2.6	1.4	-1.1	-1.7	-1.9	-2.3	-0.9	-1.1	-2.0	-0.7	0.1	1.5	0.4	1.1	2.5	0.8	2.0	2.1
Medication: Co-codamol	1.9	2.2	6.5	-0.5	-1.9	1.1	1.1	1.7	-2.2	1.6	-1.7	-2.1	-1.9	-2.5	-0.7	-1.8	-1.2	-0.0	0.4	1.4	0.2	1.1	1.7	0.8	-0.3	2.4
Mouth/teeth dental problems: Dentures	1.9	3.2	7.2	-2.4	-2.7	-0.5	-0.5	-0.3	-2.5	-0.6	-2.3	-2.7	-2.5	-2.4	-2.4	-2.0	-2.7	0.9	-1.6	-1.0	-1.7	-1.2	0.3	-1.5	-0.5	1.0
Gout (self-reported)	1.9	2.7	13.6	3.7	-1.0	-0.7	-1.0	-0.8	-0.6	-2.8	-0.4	-0.6	-0.8	0.0	-1.0	1.8	-0.9	-2.5	-1.1	-1.8	0.5	-1.2	-2.1	-1.4	3.4	-0.3
Illness, injury, bereavement, stress in last 2 years	1.9	2.3	6.2	-1.9	-1.7	-1.0	-1.0	0.0	-0.7	-0.2	-2.0	-1.5	-0.9	-0.9	-2.5	-2.4	-0.7	2.2	-1.2	-1.2	-2.5	-1.5	-1.5	-1.5	-1.6	-1.1
Handedness (chirality/laterality): Left-handed	1.9	2.3	6.0	2.3	1.9	0.9	0.7	0.7	1.5	-0.2	2.5	1.6	1.7	1.7	2.0	2.1	0.7	-1.3	1.5	0.9	1.5	1.5	-0.1	1.5	2.2	-0.1
Leg fat percentage (left)	1.9	6.7	18.8	-2.6	-4.3	-0.7	-0.5	0.6	-3.9	0.8	-3.9	-3.9	-3.6	-3.8	-4.0	-3.4	-2.3	0.7	-2.0	-1.0	-2.2	-1.5	1.3	-2.1	-1.2	1.4
Number of operations (self-reported)	1.9	2.8	8.3	-2.2	-1.9	-0.9	-1.0	0.1	-1.3	0.0	-2.2	-1.7	-1.3	-1.4	-2.9	-2.6	-1.2	2.1	-1.3	-1.1	-2.5	-1.7	-1.1	-1.4	-1.9	-1.2
Medication for hormone replacement therapy	1.8	2.0	4.6	-1.2	-1.2	-1.4	-1.2	-1.8	-1.4	-0.9	-2.0	-1.2	-1.6	-1.1	-1.7	-1.4	-1.7	1.3	-2.1	-1.2	-1.4	-1.7	0.0	-1.6	0.4	-1.4
Fed-up feelings	1.8	3.2	16.5	0.4	-0.5	-1.5	-1.4	-1.9	-1.1	-3.3	0.0	-0.2	-1.2	0.2	-0.9	2.7	-1.8	-4.1	-1.9	-2.1	0.6	-1.5	-0.7	-2.1	2.9	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.8	2.8	7.4	2.0	0.3	2.5	2.4	1.9	-1.0	1.9	0.4	0.1	-0.0	-0.7	0.9	0.3	0.3	-1.1	1.6	2.5	2.5	2.1	2.7	2.1	1.8	1.8
Pain type(s) experienced in last month: Hip pain	1.8	2.3	7.0	-0.5	-2.6	0.3	0.3	0.7	-2.1	1.2	-2.1	-2.4	-2.0	-2.5	-1.9	-2.3	-0.9	0.7	-0.3	0.5	-0.6	0.1	1.5	-0.2	-1.1	1.7
Waist circumference	1.7	6.4	17.2	-2.7	-4.2	-0.7	-0.6	0.5	-3.1	0.3	-3.6	-3.6	-3.1	-3.1	-4.1	-3.5	-3.3	1.8	-1.9	-1.3	-3.1	-1.5	-0.6	-1.7	-1.4	0.6
Chronic bronchitis/emphysema (mother)	1.7	2.0	4.5	-1.4	-1.6	-1.0	-1.1	-0.5	-1.9	-0.4	-1.9	-1.6	-1.7	-1.5	-2.1	-1.5	-1.3	0.8	-1.4	-1.1	-1.1	-1.9	-0.2	-1.9	-1.6	0.3
Heart disease (mother)	1.7	2.0	4.7	-0.5	-1.8	-1.1	-1.1	-1.8	-1.8	-1.4	-1.8	-1.5	-1.8	-1.2	-1.0	0.1	-2.2	-0.1	-1.9	-1.5	-1.5	-1.3	0.3	-1.9	1.8	-0.3
Hypothyroidism (self reported)	1.6	3.7	16.7	-0.4	-0.6	-2.2	-2.2	-1.9	0.5	-4.1	0.2	-0.2	-0.2	0.8	-1.3	2.5	-0.3	-2.5	-1.6	-3.2	0.3	-3.0	-2.1	-2.6	2.2	-1.6
Chronotype (morning person)	1.6	3.6	13.4	-1.5	0.9	-2.6	-2.7	-2.1	2.0	-3.0	0.2	0.8	1.1	2.0	-0.8	0.6	-0.6	0.7	-1.2	-2.6	-2.0	-1.8	-3.7	-1.4	-1.0	-3.0
Relative age of first facial hair	1.6	3.3	10.7	-1.3	-2.5	-0.4	-0.3	0.7	-3.1	-0.1	-1.9	-2.8	-3.3	-3.1	-1.5	-1.4	-2.6	-0.3	-1.6	-0.5	-0.4	-1.3	2.2	-1.4	0.4	1.6
Diabetes (mother)	1.6	2.0	4.4	-2.1	-2.1	-0.7	-0.7	-1.2	-1.3	-0.0	-2.0	-1.8	-1.6	-1.4	-1.9	-1.6	-2.0	1.5	-1.4	-0.9	-1.6	-1.2	-0.4	-1.0	-1.4	0.1
Alcohol usually taken with meals	1.6	2.6	7.1	0.3	-0.1	2.3	2.4	2.0	-0.6	2.6	0.1	-0.7	0.3	-1.2	0.2	-2.0	1.0	2.7	2.1	2.2	0.2	1.7	1.3	1.9	-1.2	2.0
Mouth/teeth dental problems	1.6	2.4	7.4	1.4	2.6	-0.2	-0.0	-0.1	2.6	0.3	1.8	2.6	2.6	2.7	1.4	0.9	2.3	-0.5	0.6	-0.1	0.4	0.1	-1.7	0.5	-0.7	-1.8
Birth weight of first child	1.6	2.9	7.1	-1.8	-2.7	-1.5	-1.3	-0.5	-1.8	-1.2	-2.3	-2.3	-2.1	-1.7	-2.4	-1.7	-2.3	0.4	-1.9	-1.6	-1.3	-2.0	0.4	-1.9	-0.7	0.5
Number of full brothers	1.6	2.1	8.7	-0.3	-1.5	0.0	0.2	0.0	-3.0	0.5	-1.7	-2.1	-2.3	-2.4	-0.9	-1.4	-1.5	0.6	-0.7	0.1	-0.3	-0.6	2.3	-0.9	1.3	2.0
Wears glasses or contact lenses	1.6	1.9	5.7	-1.9	-1.8	-0.8	-0.6	-0.8	-1.2	-0.3	-1.8	-1.6	-1.2	-1.4	-2.4	-1.5	-1.1	1.8	-1.2	-1.1	-1.5	-1.7	-0.0	-1.5	-0.9	-0.1
Bipolar Disorder or Schizophrenia	1.5	3.7	20.2	1.0	2.2	0.0	0.0	0.1	1.4	-0.7	1.4	1.8	0.9	1.5	3.1	3.0	1.3	-4.5	0.7	0.8	3.4	1.2	1.7	1.1	3.0	0.3
Verbal and Numeric Reasoning (VNR)	1.5	3.7	20.3	-1.3	-2.1	-0.9	-0.8	-0.3	-0.6	0.2	-2.1	-1.3	-0.4	-0.7	-3.0	-2.9	-1.1	4.5	-0.8	-1.0	-3.0	-1.3	-2.2	-1.1	-3.5	-1.0
Severe depression (siblings)	1.5	1.6	5.4	1.1	0.9	1.4	1.3	1.6	0.2	1.7	0.8	0.6	0.5	-0.1	1.5	0.2	1.0	0.1	1.6	1.9	1.7	1.6	2.3	1.9	1.0	0.4
Average weekly fortified wine intake	1.5	1.7	3.8	1.2	1.0	1.5	1.4	0.5	1.4	1.6	0.9	1.6	1.8	1.3	1.0	0.3	1.8	0.8	1.7	1.7	0.9	1.8	0.0	2.0	-1.2	-0.4
Neck or shoulder pain in last month	1.5	2.2	11.6	1.5	-0.3	1.5	1.5	0.9	-1.3	1.8	0.2	-0.7	-0.8	-1.3	0.9	-0.1	0.3	-1.0	1.3	2.0	1.5	2.0	2.6	1.3	0.7	3.4
Average weekly red wine intake	1.5	2.3	5.3	0.1	2.3	1.1	1.1	0.6	1.8	1.6	1.6	2.1	2.3	1.7	1.9	0.2	1.9	1.4	1.9	1.5	0.3	1.5	-0.7	1.8	-0.6	-1.2
Osteoporosis (self-reported)	1.5	1.8	8.3	0.1	1.4	0.7	0.8	-0.8	0.5	-0.4	1.8	1.4	0.9	1.0	0.7	2.9	0.7	-2.6	0.8	0.7	2.8	0.7	0.5	1.0	1.9	0.0
Cholesterol lowering medication	1.5	2.2	8.5	-0.5	-2.2	-0.0	-0.2	0.6	-2.2	-1.7	-1.3	-2.4	-1.7	-1.6	-2.2	-0.6	-2.9	0.3	-0.6	-1.3	-1.7	-0.9	-1.2	-1.3	0.9	1.3
Intelligence (Savage-Jansen 2018)	1.4	4.3	28.3	-1.8	-2.3	-0.4	-0.4	-0.5	-0.8	0.4	-1.9	-1.7	-0.5	-1.1	-3.6	-3.2	-1.1	5.3	-0.5	-0.8	-3.0	-1.2	-2.1	-0.8	-3.3	-0.5
Alzheimer’s Disease (in mother)	1.4	1.6	4.1	1.0	2.0	0.5	0.4	1.0	1.1	0.2	1.8	1.9	1.5	1.5	2.0	1.9	1.7	-1.7	0.7	0.3	1.2	0.4	0.6	0.2	1.4	-0.5
Allergy	1.4	3.2	9.9	-1.7	0.7	-2.5	-2.4	-3.1	1.4	-2.4	0.4	1.0	0.4	1.6	-0.7	1.6	0.5	-1.4	-1.9	-2.5	-0.0	-2.5	-2.4	-2.1	-0.6	-2.2
Alcohol intake frequency.	1.4	3.2	8.9	-1.5	-2.7	-0.8	-0.8	-0.1	-2.5	-0.9	-2.3	-2.7	-2.7	-2.4	-2.3	-1.3	-3.0	0.8	-1.7	-1.2	-1.5	-1.4	0.3	-1.9	-0.2	0.8
Breast cancer (self-reported)	1.4	1.7	5.5	1.3	0.1	2.0	1.9	1.9	0.1	1.7	0.5	-0.2	0.2	-0.5	0.8	-0.1	-0.2	0.1	1.8	2.0	1.5	2.2	0.7	2.3	0.0	1.5
Mother’s age at death	1.4	1.8	4.1	0.8	1.2	1.5	1.4	0.7	0.2	0.9	1.5	1.1	0.9	0.5	2.0	1.1	1.3	-1.4	1.4	1.8	1.9	2.0	1.5	1.7	0.7	1.2
Schizophrenia (2014)	1.3	3.0	11.9	1.2	2.0	0.2	0.1	-0.2	1.5	-0.4	1.3	1.8	1.1	1.5	2.6	2.5	1.4	-3.5	0.6	0.9	2.9	1.2	1.5	1.4	3.0	0.0
Leg fat-free mass (left)	1.3	7.0	17.3	-2.4	-4.0	-1.4	-1.2	0.5	-3.2	0.5	-4.1	-3.3	-3.3	-3.2	-4.2	-3.9	-2.5	1.4	-2.5	-1.4	-3.1	-2.3	0.1	-2.4	-2.0	-0.2
Leg predicted mass (left)	1.3	7.1	17.6	-2.5	-4.1	-1.4	-1.2	0.5	-3.3	0.6	-4.2	-3.4	-3.4	-3.3	-4.2	-4.0	-2.5	1.5	-2.5	-1.4	-3.1	-2.3	0.1	-2.4	-2.1	-0.2
Medication: Amlodipine	1.3	1.9	7.3	2.7	0.9	1.5	1.5	1.7	0.9	0.6	1.7	0.9	1.4	0.9	0.7	1.2	1.1	-1.2	1.9	1.2	1.6	1.5	-0.3	1.6	0.5	1.7
Exposure to tobacco smoke outside home	1.3	1.7	9.1	-3.0	-1.7	-0.1	-0.0	0.1	-1.7	0.4	-1.6	-1.6	-1.7	-1.5	-1.2	-1.2	-1.6	0.5	-0.7	-0.2	-0.7	-0.0	0.3	-0.5	-1.6	1.8
Migraine (self-reported)	1.3	1.6	4.9	1.7	1.7	0.8	0.9	-0.0	2.2	0.4	1.7	1.7	2.1	1.9	1.4	1.0	1.8	0.8	1.3	0.3	0.4	0.6	-1.0	1.0	-0.2	-0.4
Knee pain experienced in last month	1.3	2.1	4.5	-1.0	-1.5	-2.1	-2.0	-1.4	-0.8	-1.6	-1.3	-1.1	-1.7	-0.8	-1.8	-0.3	-1.2	-1.5	-2.0	-1.9	-0.5	-1.9	-0.6	-2.1	-0.6	-0.5
Eye problems/disorders: Glaucoma	1.3	1.5	3.9	-1.2	-1.2	-1.0	-0.9	-0.7	-1.7	-0.8	-1.2	-1.5	-1.7	-1.5	-1.3	-0.6	-1.3	0.5	-1.5	-1.4	-1.5	-1.8	0.1	-2.0	0.1	-0.0
Medication: Lisinopril	1.3	1.6	4.3	-1.9	-1.4	-0.8	-0.8	-0.4	-0.6	-0.6	-1.5	-1.2	-0.9	-0.7	-1.5	-1.9	-1.2	2.1	-0.9	-1.0	-2.1	-1.2	-1.0	-1.2	-1.7	0.2
Bipolar Disorder (2018)	1.2	2.0	7.4	1.4	1.8	0.7	0.6	0.9	1.1	0.3	1.4	1.2	0.9	0.9	2.7	1.6	1.1	-2.3	1.4	1.3	2.3	1.5	1.3	1.3	1.2	0.0
Worrier / anxious feelings	1.2	2.2	5.2	2.1	2.1	0.7	0.6	0.1	1.6	0.1	1.8	1.8	1.6	1.5	1.2	2.1	1.6	-1.8	1.4	0.8	1.9	0.8	-0.1	1.4	2.3	-0.7
Asthma	1.2	2.3	6.4	-0.4	-2.2	0.2	0.1	0.9	-1.9	0.3	-2.2	-2.3	-2.0	-2.2	-2.0	-2.2	-2.5	1.9	-0.9	-0.2	-1.6	-0.5	0.6	-0.6	-0.5	0.7
Age at first live birth	1.2	2.1	9.3	-0.2	1.6	-0.8	-0.8	-1.5	2.6	-0.2	0.9	2.0	2.0	2.0	0.5	0.8	2.1	1.7	0.4	-0.3	-0.1	-0.8	-1.8	0.1	-1.0	-3.1
Qualifications: nursing, teaching	1.2	1.8	16.7	-0.6	-0.6	0.8	0.7	1.1	0.5	1.6	-0.8	-0.5	0.4	-0.5	-0.6	-2.3	0.3	4.1	0.7	0.4	-2.0	0.0	-0.9	0.5	-2.6	-0.4
Neuroticism (Nagel 2018)	1.1	2.6	11.9	2.4	1.8	1.1	1.1	0.8	0.3	0.4	1.7	1.3	0.7	0.7	1.4	2.3	1.5	-3.5	0.6	0.9	2.7	0.5	1.7	0.7	3.1	0.1
Schizophrenia (2018)	1.1	2.2	15.5	0.3	1.4	-0.6	-0.5	-0.6	0.9	-1.2	0.7	1.4	0.5	1.2	1.8	2.6	0.7	-3.9	-0.2	-0.0	2.5	0.3	1.1	0.3	2.8	0.0
Alzheimer’s Disease (including proxy)	1.1	1.6	4.4	1.3	1.8	0.6	0.4	0.5	1.5	0.0	1.6	2.1	1.8	2.0	1.3	1.6	1.8	-1.3	0.9	0.2	0.8	0.4	-0.6	0.4	1.4	-0.7
Relative age voice broke	1.1	1.7	6.6	-1.0	-0.8	1.1	1.3	1.8	-2.2	1.0	-0.3	-1.5	-1.7	-2.1	-0.1	-0.3	-0.8	-1.4	0.2	0.8	1.3	0.2	2.6	0.1	1.2	1.4
Taking other prescription medications	1.1	1.7	8.6	1.8	0.6	0.5	0.5	0.2	0.9	-1.1	1.5	1.0	1.0	1.1	-0.5	2.4	0.9	-2.3	0.7	0.1	2.4	0.3	-0.5	0.8	2.9	-0.5
Neuroticism score	1.1	2.4	7.6	2.1	1.6	0.8	0.8	0.2	0.8	0.1	1.8	1.8	1.4	1.3	1.0	2.4	1.8	-2.7	1.3	0.9	2.8	1.0	0.1	1.3	2.4	0.0
Number of full sisters	1.1	1.4	3.5	-1.1	-1.5	0.2	0.4	0.3	-1.7	0.7	-1.4	-1.6	-1.9	-1.7	-0.8	-0.9	-1.8	-1.8	-0.4	0.6	0.7	0.6	1.2	0.1	0.3	1.8
Had major operations	1.1	1.2	4.5	-0.6	-1.1	0.8	0.7	1.3	-1.8	0.9	-1.4	-1.3	-0.9	-1.6	-0.8	-1.8	-0.9	2.1	0.2	0.5	-1.3	-0.0	1.2	0.1	-0.2	0.3
Diabetes diagnosed by doctor	1.1	1.9	6.9	-1.1	-1.8	-0.1	-0.2	0.0	-1.8	-1.1	-1.5	-2.0	-1.6	-1.4	-2.0	-0.9	-2.6	1.2	-1.0	-1.2	-1.7	-1.1	-0.5	-1.3	-0.2	1.3
Mouth/teeth dental problems: Mouth ulcers	1.1	1.8	4.8	1.2	1.4	1.2	1.0	0.4	0.8	0.8	1.6	1.3	1.1	0.6	1.7	1.5	1.9	-0.7	1.5	1.6	2.2	1.3	1.8	1.5	1.3	0.3
Hearing aid user	1.1	1.3	8.9	1.7	0.4	-0.2	-0.1	0.1	0.8	-0.6	1.4	1.0	0.9	1.1	0.3	1.9	1.2	-3.0	0.8	0.3	1.7	1.1	-0.4	0.8	0.9	-0.1
Average weekly beer plus cider intake	1.1	1.6	4.1	0.7	0.5	-1.7	-1.8	-1.4	1.2	-1.8	0.5	0.9	0.2	1.3	0.5	1.8	0.4	-2.0	-1.6	-1.8	0.5	-1.3	-0.9	-1.2	0.9	-1.3
Body Mass Index (BMI) (2010)	1.0	1.4	4.0	-1.1	-1.6	0.3	0.2	1.0	-1.7	1.7	-1.7	-1.1	-1.1	-1.5	-1.7	-2.0	-0.3	1.6	-0.1	0.8	-0.6	-0.0	1.3	0.0	-1.2	0.6
Crohns Disease (2012)	1.0	1.7	9.4	0.8	-1.1	-0.1	0.2	0.0	-1.9	-0.8	-0.3	-0.6	-1.2	-1.1	-1.0	1.4	-1.3	-2.2	-0.3	-0.2	1.6	-0.4	1.8	-0.4	3.1	1.9
Systolic Blood Pressure	1.0	5.0	20.4	2.5	1.7	-0.6	-0.8	-2.1	3.4	-3.2	2.9	2.4	2.9	3.6	0.0	3.5	0.1	-1.1	0.3	-1.6	0.1	-0.5	-4.5	0.2	1.1	-2.1
Angina	1.0	1.3	3.8	-1.4	-1.5	-0.4	-0.3	0.2	-1.9	-0.3	-1.2	-1.6	-1.4	-1.5	-1.6	-1.1	-1.5	0.9	-0.9	-0.9	-1.7	-0.7	0.3	-1.3	-0.6	0.7
Medication: Metformin	1.0	1.4	6.1	-0.9	-2.2	-0.2	-0.3	0.4	-1.1	-0.8	-1.2	-2.0	-1.6	-1.3	-2.1	-1.0	-2.5	0.5	-0.8	-0.8	-0.9	-0.7	-0.6	-0.7	-0.6	0.7
Age when periods started (menarche)	1.0	2.5	11.3	-0.3	-1.0	0.5	0.6	2.7	-2.8	1.5	-0.9	-1.8	-2.4	-2.7	0.6	-1.6	-1.0	-0.4	-0.0	1.1	0.5	0.1	3.4	0.1	1.7	1.0
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	3.0	-1.1	-1.3	-1.0	-1.2	-0.7	-1.4	-1.2	-1.4	-1.3	-1.2	-0.9	-1.2	-1.3	-1.4	0.8	-1.3	-1.1	-1.7	-1.0	0.1	-1.5	-0.5	-0.4
Prospective memory result	1.0	1.2	5.6	0.6	0.8	0.3	0.4	0.4	-0.3	0.0	0.9	0.8	0.1	0.2	1.3	2.0	1.2	-2.4	0.7	0.6	2.0	0.5	1.8	0.4	1.8	0.6
Pulse wave reflection index	1.0	1.2	4.2	0.7	1.3	0.4	0.3	-0.0	1.5	-1.2	2.0	1.0	1.2	1.3	1.7	2.1	0.3	-1.1	0.8	-0.1	0.7	0.6	-0.5	0.6	1.8	-0.3
Qualifications: College or University degree	1.0	3.2	23.4	-2.4	-0.9	0.0	0.0	0.3	-0.1	1.9	-1.9	-0.8	-0.4	-1.1	-1.8	-3.2	-0.6	4.8	0.1	0.4	-2.2	-0.5	-0.8	0.3	-3.8	-0.4
Illnesses of father: Heart disease	1.0	1.4	5.1	0.3	1.0	-0.5	-0.5	-1.5	1.4	-1.7	1.1	1.3	1.4	1.6	0.2	2.3	0.6	-1.1	0.0	-1.0	0.4	-0.5	-1.3	-0.2	2.1	-1.4
Leg fat-free mass (right)	1.0	5.3	14.3	-2.1	-3.6	-1.2	-1.0	0.5	-2.7	0.5	-3.6	-2.8	-2.8	-2.7	-3.8	-3.5	-2.0	1.2	-2.1	-1.2	-2.7	-2.0	-0.1	-2.0	-1.9	-0.3
Loneliness, isolation	1.0	1.3	3.2	-0.9	-0.7	-1.3	-1.3	-1.0	-0.9	-1.6	-0.7	-0.7	-0.8	-0.3	-1.8	0.2	-1.2	-1.2	-1.4	-1.7	-0.7	-1.6	-1.5	-1.5	0.7	-1.0
Asthma (self-reported)	1.0	2.0	5.5	-0.2	-2.0	0.1	0.0	1.0	-1.6	0.3	-2.0	-2.0	-1.8	-1.9	-1.9	-2.2	-2.4	1.9	-0.8	-0.2	-1.8	-0.5	0.2	-0.6	-0.7	0.6
Leg predicted mass (right)	1.0	5.3	14.4	-2.1	-3.6	-1.2	-1.1	0.5	-2.8	0.5	-3.6	-2.9	-2.8	-2.7	-3.8	-3.5	-2.0	1.2	-2.2	-1.3	-2.7	-2.0	-0.1	-2.1	-1.9	-0.4
Basal metabolic rate	1.0	5.3	13.2	-2.1	-3.5	-1.2	-1.0	0.5	-2.9	0.6	-3.6	-3.0	-2.9	-2.9	-3.6	-3.5	-2.0	1.3	-2.1	-1.1	-2.7	-1.9	0.1	-2.0	-1.6	-0.4
Arm fat-free mass (left)	1.0	5.0	12.0	-2.2	-3.4	-1.0	-0.9	0.6	-2.8	0.5	-3.5	-3.0	-2.9	-2.9	-3.4	-3.4	-2.1	1.6	-1.9	-1.0	-2.5	-1.8	0.2	-1.7	-1.6	-0.4
Fractured/broken bones in last 5 years	1.0	1.3	3.9	-1.2	-1.0	-0.7	-0.5	-0.3	-1.8	-1.1	-0.8	-1.3	-2.0	-1.7	-0.2	0.5	-1.7	-1.5	-1.0	-0.2	0.3	-0.5	1.7	-0.6	1.5	0.9
Arm predicted mass (left)	1.0	4.9	11.9	-1.9	-3.5	-1.1	-0.9	0.7	-2.8	0.5	-3.4	-3.0	-2.9	-3.0	-3.3	-3.4	-2.0	1.5	-1.9	-0.9	-2.5	-1.7	0.5	-1.7	-1.4	-0.3
Depressed Affect (Nagel 2018)	0.9	2.0	14.5	1.8	0.7	-0.5	-0.4	0.0	-0.6	-1.5	0.9	0.4	-0.5	0.3	0.3	2.2	-0.2	-3.8	-0.9	-0.9	1.5	-0.6	0.9	-1.0	3.5	0.0
Prostate Cancer	0.9	1.2	3.8	1.7	1.3	-0.1	-0.2	-1.1	1.9	-0.2	1.8	1.6	1.3	1.5	1.3	1.6	1.3	-0.3	0.2	0.1	1.3	0.4	-0.6	0.6	-0.4	-0.4
Rheumatoid Arthritis	0.9	1.3	4.4	0.3	1.3	1.1	1.2	1.1	0.9	0.1	1.8	0.8	1.0	0.6	1.2	1.5	1.2	-2.0	1.3	0.7	2.1	0.6	0.0	1.0	0.6	0.4
Type 2 Diabetes (T2D) (2018)	0.9	1.7	5.8	0.2	-0.7	-1.0	-1.1	-1.3	-0.9	-2.4	-0.7	-0.7	-0.7	-0.0	-1.3	0.6	-2.2	0.6	-1.6	-2.0	-1.8	-1.4	-1.4	-1.7	1.4	-0.3
Diabetes (father)	0.9	1.1	6.6	-0.7	-1.2	0.4	0.2	0.8	-0.8	0.5	-1.0	-1.2	-0.5	-1.0	-0.9	-1.9	-0.9	2.6	0.1	-0.1	-2.0	0.0	-0.5	-0.3	-1.6	0.4
Maternal smoking around birth	0.9	1.3	4.8	-0.4	-1.0	-1.0	-0.9	-1.5	-1.1	-1.7	-0.4	-0.9	-1.3	-0.6	-0.7	1.0	-1.2	-2.2	-1.3	-1.1	0.5	-0.8	-0.1	-1.1	2.0	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.3	4.3	0.3	0.1	0.9	0.8	1.4	-1.4	0.5	0.3	-0.8	-1.2	-1.4	1.1	0.4	-0.5	-2.1	0.3	0.7	1.6	0.6	1.9	0.5	2.0	1.9
Fluid intelligence score	0.9	1.8	11.6	-0.1	-0.5	0.3	0.2	0.2	0.7	0.9	-0.8	-0.1	0.9	0.4	-1.7	-1.9	-0.4	3.4	0.1	-0.3	-2.0	-0.4	-2.7	0.1	-2.6	-1.3
Medication: Cholesterol lowering	0.9	1.3	4.7	-0.8	-1.1	-0.5	-0.5	-0.4	-0.8	-1.6	-0.8	-1.3	-0.8	-0.4	-1.7	-0.2	-2.2	0.4	-1.0	-1.6	-1.8	-1.1	-1.9	-1.4	-0.1	0.4
Medication: Lansoprazole	0.9	1.1	3.2	0.3	-1.0	1.0	1.1	1.2	-0.9	0.5	-0.2	-1.0	-0.8	-1.1	-0.3	0.3	-0.8	-1.4	0.9	1.0	0.9	1.4	0.9	1.1	1.7	1.8
Peak expiratory flow (PEF)	0.9	2.1	5.3	-0.7	-1.8	1.1	1.2	2.0	-1.5	1.9	-1.4	-1.9	-1.3	-2.2	-1.2	-2.2	-0.8	1.4	0.6	0.8	-0.6	0.2	0.3	0.4	-1.7	2.3
Number of children fathered	0.9	1.0	4.9	-0.9	-1.3	-1.0	-0.9	-0.7	-0.6	-0.5	-1.0	-1.1	-0.8	-0.7	-1.2	-1.1	-0.4	1.1	-0.6	-0.8	-0.7	-0.9	-1.5	-1.1	-2.2	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	3.8	0.1	-0.4	0.9	0.9	1.4	-1.2	1.9	-0.8	-0.9	-0.9	-1.5	-0.0	-1.4	0.1	0.5	0.5	1.2	0.4	0.7	1.9	0.4	-0.2	1.6
Angina (self-reported)	0.9	1.1	2.7	-1.1	-1.4	-0.4	-0.4	0.0	-1.6	-0.5	-1.1	-1.5	-1.3	-1.2	-1.6	-0.8	-1.4	0.7	-0.9	-0.9	-1.6	-0.7	0.2	-1.2	-0.5	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	3.9	-0.3	-1.2	0.4	0.4	0.1	-1.0	0.8	-1.3	-1.4	-1.2	-1.5	-1.4	-2.0	-1.5	1.9	-0.2	0.5	-0.8	-0.1	0.7	0.4	-0.7	-0.0
Family relationship satisfaction	0.9	1.1	3.5	0.9	0.8	1.3	1.3	0.7	-0.1	1.3	0.5	0.9	1.0	0.4	0.6	0.5	1.9	-0.9	1.5	1.4	1.3	1.1	0.7	1.0	0.8	1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	3.7	0.8	-1.3	0.4	0.4	0.1	-1.3	-0.0	-0.8	-1.7	-1.5	-1.7	-0.9	-0.8	-1.9	0.7	-0.1	0.3	-0.4	0.4	1.1	0.3	1.1	1.2
Mood swings	0.9	1.7	14.0	1.2	0.2	-0.3	-0.2	-0.5	-0.6	-1.3	0.6	0.3	-0.4	0.2	0.3	2.3	0.2	-3.7	-0.6	-0.6	1.9	-0.3	0.7	-0.6	2.9	0.6
Ever had bowel cancer screening	0.9	1.1	2.6	0.8	0.2	1.4	1.5	1.4	-0.6	1.1	0.6	-0.1	-0.1	-0.6	1.0	-0.0	0.6	-1.1	1.3	1.6	1.1	1.5	1.6	1.2	0.8	1.1
Illnesses of father: None of the above (group 1)	0.9	1.2	4.2	-0.5	-1.1	0.3	0.3	0.6	-1.3	2.0	-1.4	-0.9	-1.3	-1.4	-0.6	-1.4	-0.3	0.2	-0.0	1.4	0.4	0.9	1.3	0.6	-1.9	1.2
Heart disease (siblings)	0.9	1.1	3.9	-1.2	-1.2	-0.2	-0.3	0.1	-2.0	-0.4	-1.4	-1.5	-1.6	-1.6	-0.9	-0.9	-1.5	-0.4	-0.8	-0.5	-0.8	-0.5	0.9	-1.0	0.4	0.9
Depression (Nagel 2018)	0.8	1.2	4.4	1.5	2.0	0.6	0.5	0.5	0.5	0.1	1.5	1.4	0.6	0.8	2.1	1.6	0.4	-1.9	-0.3	0.2	1.4	-0.0	0.8	0.1	1.4	-0.6
Crohns Disease (2017)	0.8	1.8	10.3	1.2	-1.1	-0.6	-0.3	-0.7	-2.0	-1.4	-0.7	-1.0	-1.7	-1.3	-1.2	1.2	-2.0	-2.0	-0.8	-0.5	1.2	-0.7	0.9	-0.6	3.2	0.9
Breast Cancer	0.8	1.9	5.4	1.9	-0.4	1.4	1.4	2.1	-1.8	1.0	-0.1	-1.0	-0.8	-1.4	0.2	-0.3	-0.4	-0.6	1.3	1.5	1.0	1.3	2.2	1.0	2.3	2.2
Waist Hip Ratio (WHR)	0.8	3.7	11.8	1.5	1.0	1.2	0.9	0.3	2.3	-2.6	2.8	1.0	1.8	2.0	1.2	3.3	-2.6	-0.4	1.8	-0.0	0.5	1.7	-3.4	2.3	2.6	1.0
Hearing difficulty/problems: Yes	0.8	1.3	2.9	1.6	0.7	1.4	1.5	1.1	-0.3	0.7	0.9	0.5	0.4	0.0	1.3	0.9	0.2	-1.5	1.4	1.5	1.3	1.7	0.9	1.4	1.3	0.6
Bilateral oophorectomy (both ovaries removed)	0.8	1.0	3.1	0.2	0.2	-1.2	-1.3	-1.8	0.3	-1.4	-0.3	0.2	-0.5	0.4	-0.4	0.9	-1.5	-1.0	-1.4	-1.1	-0.5	-0.7	-0.9	-0.7	1.5	-1.3
Medication: Levothyroxine sodium	0.8	1.3	4.7	-1.2	-0.7	-1.2	-1.1	-0.9	0.7	-2.2	0.1	-0.3	-0.1	0.4	-1.3	1.2	0.1	-1.8	-0.8	-1.8	0.5	-1.7	-1.6	-1.4	0.2	-1.1
High blood pressure (mother)	0.8	1.1	3.2	1.4	-0.0	1.5	1.6	0.7	-0.0	1.1	0.3	0.5	0.6	0.2	0.3	0.7	0.5	-1.1	1.2	1.4	0.8	1.8	0.6	1.4	1.3	1.7
Time employed in main current job	0.8	1.0	2.7	1.6	0.8	0.7	0.9	0.6	1.0	0.6	1.2	1.5	1.6	1.5	0.1	0.7	1.3	-0.5	0.8	0.6	0.7	0.5	-1.6	0.8	0.1	-0.3
Hair/balding pattern: Pattern 3	0.8	1.1	3.4	-0.8	0.6	-0.8	-0.9	-0.7	1.3	-1.0	0.2	1.1	1.1	1.5	-0.3	0.8	1.1	-0.8	-0.5	-1.3	-0.9	-1.2	-1.8	-1.2	-0.8	-1.9
Qualifications: A levels/AS levels or equivalent	0.8	1.8	8.5	-1.0	0.7	0.1	0.1	0.2	1.9	0.9	0.5	0.9	1.8	1.3	0.1	-0.7	1.6	2.9	1.0	-0.1	-1.1	-0.1	-2.6	0.4	-2.5	-1.3
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.1	3.2	0.8	0.8	0.2	0.1	-0.7	1.8	-0.1	1.4	1.0	1.3	1.2	0.9	1.4	1.8	-1.4	1.0	0.5	1.7	0.7	-0.4	0.8	-0.3	-0.4
Headache pain in last month	0.8	1.4	4.6	1.7	0.1	1.5	1.5	1.0	-0.3	0.9	0.7	0.2	0.3	-0.1	1.0	1.0	0.5	-0.8	1.6	1.5	1.4	1.7	1.4	1.2	0.9	2.1
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	6.4	-0.5	-1.0	-1.2	-1.2	-0.8	-0.2	-2.5	-0.3	-0.7	-0.6	-0.1	-1.3	1.5	-0.5	-2.1	-0.9	-1.8	0.5	-1.8	-0.8	-1.7	1.5	-0.2
Shortness of breath walking on level ground	0.8	1.0	3.1	-1.4	-1.2	0.2	0.4	1.0	-1.8	0.1	-1.1	-1.6	-1.3	-1.6	-1.4	-1.2	-1.2	0.2	-0.1	0.0	-0.6	-0.2	0.7	-0.2	-0.0	1.0
Suffer from ‘nerves’	0.8	1.3	3.6	1.4	0.3	1.7	1.5	1.2	0.2	1.5	0.8	0.5	0.8	0.1	0.4	0.1	1.2	-0.3	1.7	1.8	1.6	1.5	0.4	1.9	0.3	0.5
Miserableness	0.8	1.5	10.0	1.3	0.4	0.1	0.2	0.6	-1.0	-0.8	0.7	0.4	-0.5	-0.1	0.6	1.5	0.0	-3.0	-0.2	0.1	1.7	0.1	2.0	-0.3	3.2	0.8
Medication: Atorvastatin	0.8	1.0	6.1	-0.5	-0.8	0.5	0.3	0.9	-1.8	-1.0	-0.3	-1.4	-1.4	-1.0	-0.3	-0.0	-2.5	-0.8	-0.5	-0.6	-0.7	-0.1	0.2	-0.8	0.6	1.8
Irritability	0.8	1.3	5.4	1.1	0.5	-1.2	-1.2	-1.9	-0.1	-1.3	0.6	1.0	0.2	0.9	0.1	2.1	0.5	-2.3	-1.1	-0.9	0.6	-0.8	-0.3	-0.9	1.9	-0.5
Ever depressed for a whole week	0.8	1.0	3.4	1.6	0.4	1.4	1.3	1.1	-0.3	0.9	0.4	0.2	0.3	-0.2	0.3	0.7	-0.1	-0.3	1.3	1.4	1.3	1.1	0.6	1.6	1.9	1.2
Unable to work because of sickness or disability	0.8	1.0	2.6	0.6	0.5	1.5	1.3	1.3	0.4	0.7	1.1	0.2	0.6	-0.1	0.7	0.5	0.7	0.1	1.5	1.4	1.3	1.5	0.4	1.6	0.0	1.4
Type 2 Diabetes (T2D) (2012)	0.7	0.8	4.0	-0.3	0.4	-0.7	-0.7	-1.1	0.5	-1.6	0.7	0.4	0.4	0.8	0.4	0.9	-2.0	-0.4	-0.9	-1.3	-0.7	-0.9	-1.3	-0.9	0.6	0.0
Father’s age at death	0.7	0.9	2.7	0.3	1.0	1.3	1.3	1.6	0.4	1.6	0.7	0.7	0.8	0.2	1.3	-0.2	1.2	0.8	1.2	1.1	0.3	0.9	1.0	0.9	-0.0	0.1
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	2.8	0.1	-1.4	-0.1	-0.1	-0.1	-1.3	0.3	-1.4	-1.5	-1.3	-1.6	-1.0	-1.3	-0.6	1.7	-0.1	0.2	-0.9	0.1	0.5	-0.2	-0.6	1.1
Glaucoma (self-reported)	0.7	0.9	2.2	-0.1	-1.1	-0.8	-0.6	-0.6	-1.4	-1.0	-0.8	-1.1	-1.3	-1.0	-1.0	0.2	-1.2	-0.3	-1.0	-1.0	-1.0	-1.3	-0.3	-1.5	0.5	0.1
Medication: Ibuprofen	0.7	0.8	2.7	0.2	0.9	-0.2	-0.2	-1.3	1.6	-0.4	1.2	1.0	1.1	1.2	1.0	1.2	1.4	-1.0	0.6	0.2	1.2	0.5	-0.5	0.5	-0.6	-0.7
Medication: Seretide 50 evohaler	0.7	0.8	5.4	-0.1	-0.5	0.7	0.6	0.9	-1.1	0.9	-0.6	-0.6	-0.7	-1.1	0.1	-0.8	-0.3	0.3	0.5	1.2	0.3	1.1	2.3	1.0	1.4	0.1
Long-standing illness, disability or infirmity	0.7	1.1	5.0	-0.0	-1.0	-1.3	-1.4	-1.3	-0.1	-2.2	-0.6	-0.6	-0.9	-0.2	-1.1	1.2	-1.1	-0.9	-1.3	-1.2	0.1	-0.7	0.1	-0.8	1.7	-0.7
Medication for cholesterol	0.7	1.0	5.3	-0.2	1.2	-0.3	-0.4	-0.5	1.4	1.0	0.8	1.6	1.1	1.0	1.2	0.6	2.3	-0.7	0.5	0.7	1.2	0.8	0.6	0.8	-1.2	-0.5
Osteoarthritis (self-reported)	0.7	0.9	2.5	-1.3	-1.2	-1.1	-0.9	-0.5	-1.2	-0.1	-1.5	-1.1	-1.5	-1.1	-0.8	-0.8	-0.7	-0.4	-1.6	-0.7	-0.3	-1.0	0.5	-1.0	-0.1	-0.3
Whole body water mass	0.7	3.9	10.1	-1.7	-2.9	-1.3	-1.1	0.3	-2.2	0.3	-3.1	-2.3	-2.3	-2.2	-3.2	-2.9	-1.7	1.2	-2.0	-1.2	-2.4	-1.9	-0.2	-1.9	-1.4	-0.9
Average weekly champagne plus white wine intake	0.7	0.9	2.0	1.2	0.7	1.2	1.3	1.2	0.1	1.4	0.8	0.4	0.5	-0.1	0.7	0.1	0.8	-0.3	1.3	1.4	1.3	1.0	0.9	1.3	-0.0	1.3
Myopia	0.7	1.1	3.3	0.1	0.1	-1.1	-0.8	-1.7	0.6	-1.6	0.2	0.6	0.3	1.0	-0.6	1.8	0.0	-1.5	-0.9	-1.3	0.1	-0.9	-1.7	-0.8	1.4	-0.9
Pain experienced in last month	0.7	1.2	9.7	-0.9	0.1	-0.1	-0.2	0.1	0.5	-0.0	-0.7	-0.1	0.3	0.1	-0.6	-1.6	-0.9	3.1	-0.5	-0.6	-2.0	-0.9	-1.3	-0.2	-0.9	-1.8
Alcohol drinker status: Previous	0.7	0.8	2.7	-0.8	-0.4	-1.0	-1.1	-0.4	-0.4	-1.5	-0.6	-0.5	-0.7	-0.2	-0.6	-0.2	-1.6	0.4	-1.1	-1.0	-1.1	-1.0	-0.3	-1.1	0.5	-1.4
Irritable Bowel Disease (IBD)	0.6	1.4	5.1	0.8	-1.4	-0.9	-0.6	-0.8	-1.7	-1.6	-0.8	-0.7	-1.4	-0.9	-1.3	1.3	-1.8	-2.2	-0.7	-0.5	0.9	-0.6	0.0	-0.6	2.3	0.8
Mean Putamen Volume	0.6	0.7	2.0	-0.9	0.3	-1.2	-1.1	-1.3	0.6	-1.4	0.1	0.3	-0.1	0.6	0.3	0.9	-0.2	-1.1	-1.2	-1.2	-0.3	-0.9	-0.3	-1.0	0.7	-1.2
Fasting Glucose	0.6	0.7	1.8	0.4	0.6	1.3	1.3	0.5	0.5	1.3	0.6	0.6	0.8	0.4	0.6	1.1	0.4	1.1	1.1	1.1	0.5	0.9	0.6	1.2	-0.2	-0.2
Smoking Status	0.6	1.5	6.9	0.1	-1.7	1.0	0.9	0.5	-1.7	-0.6	-0.7	-1.4	-1.3	-1.1	-1.4	0.7	-1.9	-2.4	-0.0	0.3	1.1	0.6	-0.3	0.2	1.0	2.6
Lung FEV1/FVC ratio	0.6	3.1	8.2	-1.1	-2.0	1.5	1.5	2.5	-2.3	2.5	-2.0	-2.3	-1.5	-2.6	-1.5	-2.9	-0.9	1.1	0.9	1.5	0.2	0.6	1.5	0.8	-1.5	2.0
Current tobacco smoking	0.6	0.9	3.6	-1.1	-1.7	-0.2	-0.2	-0.3	-1.2	-0.7	-1.1	-1.6	-1.5	-1.2	-1.3	-0.3	-1.9	-0.5	-0.6	-0.4	-0.3	-0.1	-0.0	-0.4	0.4	1.2
Impedance of leg (left)	0.6	2.8	8.8	1.7	2.6	0.8	0.7	-0.5	1.8	-0.5	2.6	1.9	1.7	1.7	3.0	2.9	1.1	-1.7	1.3	0.7	2.0	1.4	-0.1	1.5	1.8	0.2
Hair/balding pattern: Pattern 2	0.6	0.8	2.4	-1.1	-0.9	-0.8	-0.8	-0.1	-1.2	-0.3	-1.4	-0.9	-1.4	-1.0	-0.7	-0.8	-1.5	0.6	-1.1	-0.3	-0.5	-0.4	0.9	-0.6	0.1	-0.1
Happiness	0.6	0.8	2.7	-0.7	-1.2	-0.7	-0.7	-0.5	-0.6	-0.7	-1.2	-0.8	-0.6	-0.4	-1.6	-0.7	-0.6	-0.0	-0.9	-0.9	-1.3	-0.9	-1.4	-0.9	0.0	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	2.5	1.1	0.5	-1.0	-0.9	-0.2	1.0	-1.2	0.5	0.8	0.5	1.0	0.8	1.2	0.6	-1.6	-0.4	-1.0	-0.0	-0.7	-0.2	-0.5	0.5	-0.5
Illnesses of mother	0.6	0.7	2.7	0.3	0.4	0.6	0.7	1.2	1.0	1.3	0.6	-0.0	0.3	-0.2	0.7	-1.0	0.9	0.9	1.1	1.1	0.6	0.9	0.5	1.2	-1.6	0.0
Exposure to tobacco smoke at home	0.6	0.6	2.6	-0.8	-1.0	0.2	0.3	0.4	-1.3	0.1	-0.8	-1.1	-1.3	-1.3	-0.4	-0.2	-1.3	-0.2	-0.1	0.1	-0.1	0.2	0.8	-0.1	0.5	1.6
Worry too long after embarrassment	0.6	1.0	3.8	-0.3	0.1	1.3	1.4	1.1	-0.7	1.9	-0.3	-0.2	-0.2	-0.9	0.1	-1.1	0.7	0.4	1.3	1.8	1.2	0.8	1.4	1.1	-0.3	0.6
Medication: Blood pressure	0.6	1.1	7.7	-0.0	-0.8	-0.7	-0.7	-0.8	0.7	-1.5	0.2	-0.3	0.3	0.6	-1.9	0.0	-0.9	1.2	-0.4	-1.4	-1.2	-0.8	-2.8	-0.7	-1.2	0.1
Commuting to job workplace: Car/motor vehicle	0.6	0.6	3.0	-0.7	-0.3	-0.9	-0.8	-1.7	-0.6	-1.0	-0.2	-0.4	-0.8	-0.3	-0.2	0.3	-0.7	-1.1	-1.2	-1.0	0.3	-1.0	0.6	-1.1	0.7	-0.1
Medication: Aspirin	0.6	0.8	4.5	-0.0	0.1	-0.4	-0.5	-1.3	0.8	-1.8	0.6	0.2	0.8	1.0	-0.6	1.1	-0.8	0.2	-0.4	-1.4	-0.8	-0.8	-2.1	-0.7	0.4	-0.8
Whole body fat-free mass	0.6	3.5	9.5	-1.7	-2.8	-1.1	-1.0	0.3	-2.1	0.4	-3.0	-2.2	-2.2	-2.1	-3.1	-2.8	-1.6	1.1	-1.9	-1.1	-2.4	-1.8	-0.3	-1.7	-1.3	-0.9
Number of self-reported non-cancer illnesses	0.6	1.1	4.3	1.6	-0.6	-0.3	-0.3	-0.4	0.1	-2.1	0.4	-0.2	0.0	0.6	-1.1	1.6	-1.4	-1.8	-0.3	-1.1	0.5	-0.3	-1.2	-0.4	1.9	-0.1
Financial situation satisfaction	0.6	0.8	2.2	-0.3	-0.1	-0.9	-0.9	-1.2	-0.3	-1.4	-0.1	-0.0	-0.4	0.3	0.1	0.9	-1.1	-1.2	-1.2	-1.5	-0.6	-0.8	-1.3	-1.3	0.7	-0.8
High cholesterol (Self-reported)	0.6	1.0	4.2	1.0	-0.3	1.2	1.1	1.1	-1.1	-0.7	0.4	-0.9	-0.4	-0.5	0.0	1.1	-1.7	-1.1	0.8	0.1	0.2	0.9	-0.6	0.3	2.1	2.0
Basal cell carcinoma (self-reported)	0.6	0.8	3.5	0.0	0.7	0.3	0.2	0.6	1.0	0.9	0.2	0.8	1.1	0.8	-0.0	-0.8	1.3	1.9	0.9	0.6	-0.9	0.9	-0.8	0.9	-1.5	-0.3
HDL Cholesterol	0.5	0.8	2.6	-0.9	-1.4	-0.5	-0.3	-0.2	-1.4	0.6	-1.1	-0.9	-1.3	-1.2	-1.1	-0.8	0.4	-0.6	-0.3	0.5	0.0	0.2	1.2	-0.4	-0.6	1.6
Heel T-Score	0.5	3.9	17.6	-0.1	-1.9	1.2	1.1	2.7	-1.9	2.2	-2.6	-2.0	-1.1	-2.1	-2.0	-4.0	-1.8	4.2	0.3	0.7	-3.2	0.3	0.0	0.4	-0.1	0.8
Average weekly spirits intake	0.5	0.6	2.3	-0.4	0.6	0.4	0.4	-0.6	0.9	0.9	0.6	0.9	0.8	0.7	1.0	0.1	1.5	0.5	0.6	0.9	1.0	0.6	0.4	0.9	-1.1	-0.4
Systolic blood pressure, automated reading	0.5	1.5	3.9	-0.2	-1.1	-1.3	-1.2	-2.0	-0.3	-2.0	-0.4	-0.8	-0.8	-0.2	-1.4	-0.0	-1.9	-0.0	-1.6	-1.8	-1.5	-1.4	-1.0	-1.4	0.5	-0.9
Qualifications: CSEs or equivalent	0.5	0.6	1.6	0.5	-1.3	-0.5	-0.6	0.6	-1.1	-0.1	-1.2	-1.0	-1.2	-1.1	-0.7	-1.0	-0.2	-0.7	-0.6	-0.4	-0.4	-0.8	1.1	-0.8	-0.1	0.0
Hearing difficulty/problems with background noise	0.5	0.8	4.3	1.4	0.3	0.8	0.8	0.8	-0.9	0.1	0.3	-0.2	-0.5	-0.6	0.9	0.3	0.2	-1.8	0.3	0.7	0.7	0.6	1.9	0.3	2.1	0.6
Qualifications: None of the above	0.5	1.1	8.0	1.0	0.4	0.0	0.1	0.7	-1.1	-0.4	0.7	-0.4	-0.9	-0.7	0.7	1.1	0.3	-2.8	0.1	0.3	1.6	0.3	2.0	-0.2	1.6	1.4
Financial difficulties in last 2 years	0.5	0.7	2.5	1.1	0.5	0.9	0.9	0.4	-0.7	0.1	0.8	0.4	-0.2	0.0	0.9	1.2	-0.8	-1.6	0.4	0.6	1.1	0.8	1.1	0.3	1.2	1.3
Heart attack	0.5	0.6	2.2	-1.0	0.1	-0.6	-0.7	-0.7	0.6	-1.2	0.2	0.1	0.7	0.7	-0.5	0.1	-0.2	1.2	-0.1	-1.2	-1.3	-0.7	-1.5	-0.6	-0.9	-0.4
Illnesses of siblings	0.5	0.7	4.1	0.4	1.2	0.4	0.2	1.0	0.9	1.0	1.2	0.7	0.8	0.4	1.1	0.3	2.0	0.8	1.0	0.5	1.0	0.0	0.8	0.3	-0.1	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.9	2.5	-0.7	-1.3	-0.4	-0.5	-0.3	-1.6	-0.9	-1.0	-1.2	-1.3	-0.9	-1.5	0.2	-1.0	-1.5	-0.9	-0.8	-0.1	-0.5	-0.4	-1.1	0.4	1.0
Lung cancer (father)	0.5	0.6	1.3	0.6	-1.0	-1.0	-1.1	-0.8	0.1	-0.3	-1.1	-0.6	-0.5	-0.3	-1.1	-0.9	-0.0	0.5	-1.0	-0.6	-0.9	-0.6	-0.9	-0.5	-1.1	-0.8
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.8	1.2	0.3	0.9	0.9	0.9	-0.6	-0.1	0.8	-0.1	0.2	-0.1	0.3	1.2	0.1	-1.6	0.6	-0.1	0.5	0.3	-0.4	0.1	1.4	1.7
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	3.5	0.6	1.1	0.6	0.6	0.7	0.3	1.5	0.4	0.9	0.4	0.1	1.9	-0.2	1.4	-0.3	0.7	1.3	1.0	0.8	1.7	1.0	0.2	-0.4
Arm fat-free mass (right)	0.5	2.3	6.3	-1.1	-2.4	-0.7	-0.6	0.7	-1.9	0.6	-2.4	-1.9	-1.8	-1.9	-2.5	-2.5	-1.2	1.2	-1.3	-0.6	-1.9	-1.3	0.0	-1.1	-0.8	-0.7
Health satisfaction	0.5	0.6	3.5	-0.4	-0.8	0.7	0.8	0.2	-1.5	0.5	-0.8	-0.8	-0.6	-0.8	-1.9	-0.8	-1.2	0.0	-0.0	0.3	-0.3	0.4	-0.4	0.3	0.0	1.1
Emphysema/chronic bronchitis	0.5	0.6	1.8	0.3	0.8	-0.3	-0.3	-0.5	1.4	-1.0	0.8	1.0	1.1	1.3	0.6	0.7	0.6	0.2	0.4	0.1	0.1	0.7	-0.7	0.8	0.7	-1.2
Medication for pain relief, constipation, heartburn	0.5	0.8	4.7	-0.7	-0.5	0.2	0.3	2.2	-1.6	0.6	-1.0	-0.9	-1.1	-1.2	0.3	-1.0	-1.2	0.6	-0.1	0.0	-1.4	-0.0	0.6	-0.5	0.1	0.8
Arm predicted mass (right)	0.5	2.6	7.1	-1.2	-2.5	-0.6	-0.5	0.8	-2.0	0.8	-2.5	-2.0	-1.9	-2.1	-2.5	-2.7	-1.4	1.4	-1.3	-0.5	-2.0	-1.2	0.2	-1.1	-0.9	-0.5
Age at last live birth	0.5	0.7	2.3	-1.0	-1.0	-0.8	-0.8	-0.6	-0.9	-0.3	-1.0	-0.7	-0.9	-0.7	-0.9	-0.4	-0.3	1.0	-0.9	-0.9	-0.6	-1.4	0.3	-1.5	-0.5	-0.6
Eye problems/disorders: Cataract	0.5	0.5	3.1	-0.8	0.5	-0.4	-0.4	-0.5	0.8	-1.0	-0.0	0.4	0.7	0.9	-0.7	-0.2	-0.4	0.7	-0.4	-0.9	-0.7	-0.7	-1.7	-0.3	-0.2	-1.2
Medication: Aspirin	0.5	0.7	3.6	0.1	0.5	-0.1	-0.3	-1.0	1.0	-1.5	0.8	0.5	1.1	1.2	-0.2	1.2	-0.6	0.6	-0.0	-1.1	-0.6	-0.4	-1.9	-0.3	0.5	-0.6
Tinnitus: Yes, now most or all of the time	0.5	0.5	2.7	-1.6	-0.5	-0.1	-0.0	0.5	-1.4	0.0	-1.2	-0.5	-0.8	-0.9	-0.7	-0.6	-1.0	-0.4	-0.5	0.1	-0.6	-0.3	0.8	-0.6	0.1	0.8
Coronary Artery Disease (CAD)	0.4	0.4	1.8	-0.4	0.5	-0.7	-0.7	-0.4	-0.0	-1.4	0.1	0.7	0.5	0.7	0.3	1.0	0.6	-1.3	-0.3	-0.7	0.1	-0.5	-0.3	-0.6	1.0	0.0
Lupus	0.4	0.6	2.3	1.2	0.3	0.8	1.0	0.6	-0.4	0.5	0.9	0.3	0.2	-0.2	0.5	0.6	-0.3	-0.2	0.5	0.9	1.5	0.4	1.5	0.9	1.5	0.1
Ulcerative Colitis	0.4	0.6	2.1	0.4	-0.1	0.7	0.8	0.8	-0.9	0.2	0.4	0.1	-0.2	-0.3	0.5	1.1	-0.3	-0.8	0.9	1.0	1.4	1.0	0.8	0.9	1.2	0.0
Respiratory disease	0.4	1.0	4.2	-0.1	-1.1	-0.1	-0.1	1.2	-0.8	-0.3	-1.2	-1.3	-1.0	-1.0	-1.3	-1.4	-2.1	1.4	-0.3	-0.2	-1.7	0.0	-0.3	-0.3	-0.6	0.7
Impedance of leg (right)	0.4	1.7	6.7	1.2	2.2	0.4	0.3	-0.7	1.4	-0.7	2.0	1.4	1.2	1.3	2.6	2.4	0.5	-1.2	0.7	0.4	1.3	1.0	-0.0	1.1	1.6	0.0
Serious illness, injury or assault to yourself	0.4	0.5	2.1	0.8	0.3	0.9	0.9	1.0	0.3	0.3	0.6	0.3	0.6	0.3	0.3	0.3	-0.4	0.4	1.0	0.9	0.1	1.4	-0.3	1.4	0.1	0.9
Stomach or abdominal pain in last month	0.4	0.5	1.7	0.3	-0.6	0.5	0.6	0.0	-0.8	1.1	-0.7	-0.7	-0.8	-1.1	-0.2	-1.0	-0.1	-0.1	0.1	1.0	0.5	0.7	0.8	0.7	-0.2	1.3
Medication: Atenolol	0.4	0.5	2.9	1.7	0.5	0.8	0.9	1.6	-0.1	-0.1	0.9	0.3	0.7	0.5	-0.2	0.4	-0.3	-0.4	0.5	0.0	-0.2	0.4	-0.2	0.5	1.2	0.0
Past tobacco smoking	0.4	0.8	3.2	-0.0	1.5	-0.6	-0.5	-0.8	1.1	0.5	1.0	1.1	0.9	0.8	1.6	-0.0	1.1	1.8	0.3	0.1	-0.5	0.1	0.7	0.0	-0.3	-1.4
Had other major operations	0.4	0.5	2.8	0.5	0.3	0.7	0.8	-0.2	-0.1	1.6	0.4	0.5	0.6	0.0	-0.7	-0.5	1.7	0.8	0.6	0.8	0.9	0.1	0.2	0.4	-0.7	-0.2
Diabetes (self-reported)	0.4	0.6	2.2	-0.2	-0.8	0.3	0.1	-0.2	-1.0	-0.4	-0.7	-1.0	-0.8	-0.7	-1.3	-0.5	-1.5	1.0	-0.5	-0.4	-0.9	-0.5	-0.1	-0.6	-0.1	1.1
Falls in the last year	0.4	0.5	1.4	-1.2	-0.6	-0.6	-0.6	0.3	-1.2	0.4	-1.0	-0.6	-1.2	-0.9	-0.3	-0.9	-0.8	-0.3	-0.5	0.3	-0.4	0.0	1.1	-0.4	0.1	0.1
Pulse wave Arterial Stiffness index	0.4	0.5	2.8	0.3	-0.6	0.2	0.3	0.3	-0.7	-1.4	0.4	-0.6	-0.4	-0.4	-0.3	1.2	-1.2	-1.0	0.1	-0.4	0.1	-0.0	0.1	-0.0	1.7	0.9
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	4.8	-0.4	-0.7	0.6	0.6	1.1	-0.0	1.1	-0.6	-0.4	0.2	-0.3	-0.9	-1.6	-0.0	2.2	0.6	0.4	-1.0	0.3	-0.6	0.5	-1.2	0.2
Medication: Ventolin 100micrograms inhaler	0.4	0.5	3.0	1.4	0.2	1.2	1.2	0.4	-0.2	0.7	0.1	0.1	0.1	-0.1	0.1	0.2	-0.5	-0.1	0.7	1.0	0.5	0.8	0.1	1.0	1.7	0.2
High blood pressure (siblings)	0.4	0.5	2.5	0.8	0.2	0.5	0.5	-0.8	0.7	-0.2	0.6	0.7	0.9	1.0	0.2	0.6	-0.4	-1.0	0.4	0.5	0.1	1.2	-1.6	1.1	0.3	0.3
Pulse wave peak to peak time	0.4	0.5	3.3	-0.4	0.5	-0.3	-0.5	-0.4	0.6	1.2	-0.4	0.5	0.3	0.3	0.3	-1.2	1.0	1.1	-0.3	0.2	-0.4	-0.1	-0.3	-0.1	-1.8	-1.0
Mouth/teeth dental problems: Loose teeth	0.4	0.5	3.5	1.4	-0.7	-0.4	-0.4	-0.1	0.2	-1.0	-0.1	-0.5	-0.6	-0.2	0.0	0.8	-0.3	-1.6	-0.3	-0.3	0.4	0.4	0.3	0.0	1.9	0.4
Smoking status: Previous	0.4	0.5	1.9	0.7	-1.0	0.7	0.7	0.9	-1.1	0.0	-0.8	-0.6	-0.6	-0.6	-1.3	-0.1	-0.6	-1.4	-0.3	0.2	0.6	-0.0	-0.2	0.1	0.6	1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	1.7	-1.3	-0.9	0.2	0.2	0.2	-0.6	-0.5	-0.6	-1.2	-0.8	-0.9	-0.8	-0.2	-0.9	0.0	-0.3	-0.6	-0.3	-0.7	-0.1	-0.7	0.6	0.4
Ever taken oral contraceptive pill	0.4	0.4	1.9	0.3	-0.6	1.1	1.0	0.1	-0.5	0.7	-0.7	-0.5	-0.0	-0.4	-0.8	-0.8	-0.1	0.4	0.5	0.7	-0.2	0.7	-0.0	0.5	-0.7	1.4
Medication: Bendroflumethiazide	0.4	0.6	2.0	-0.9	-0.5	-0.4	-0.4	-0.0	-0.3	-1.2	0.0	-0.7	-0.3	0.0	-1.0	0.2	-1.2	0.1	-0.6	-1.3	-1.0	-1.0	-1.4	-1.1	-0.5	0.3
Ever smoked	0.4	0.8	6.7	0.8	-0.4	0.5	0.4	0.2	0.2	-1.0	0.2	0.1	0.1	0.3	-0.6	1.5	-0.5	-2.6	0.1	-0.1	1.2	0.3	-1.3	0.4	1.0	0.8
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.7	-0.9	-0.0	-0.5	-0.5	-0.6	0.3	-1.2	0.1	-0.1	0.6	0.5	-0.5	0.1	-0.3	1.2	-0.1	-1.1	-1.3	-0.6	-1.3	-0.6	-0.7	-0.2
Schizophrenia vs Biploar Disorder	0.3	0.4	1.5	-1.2	-0.5	0.1	0.1	-0.2	-0.9	0.7	-1.0	-0.4	-0.8	-0.9	-0.6	-1.0	-0.2	0.8	-0.2	0.6	-0.3	-0.2	1.1	0.0	0.1	-0.1
Alzheimer’s Disease (in father)	0.3	0.3	1.4	1.2	-0.6	0.8	0.7	0.1	-0.4	0.6	-0.4	-0.1	0.2	-0.1	-0.9	-0.6	0.2	0.2	0.5	0.7	-0.3	0.5	-0.7	0.6	0.6	0.8
Ovarian Cancer	0.3	0.4	2.6	0.5	-0.4	0.3	0.3	0.2	-1.2	0.1	-0.4	-0.3	-0.8	-0.9	-0.4	0.3	-0.2	-0.5	-0.2	0.5	0.8	-0.0	1.4	0.1	1.6	0.4
HbA1C	0.3	0.4	2.2	0.7	0.3	-0.0	0.0	-0.1	-0.7	-0.9	0.2	-0.0	-0.3	0.2	0.8	0.8	-1.5	-0.1	-0.2	-0.5	-0.1	0.1	0.1	-0.4	1.4	0.5
LDL Cholesterol	0.3	0.5	2.3	-0.1	-0.6	0.7	0.6	1.0	-1.1	0.8	-0.2	-0.8	-0.8	-1.1	-0.1	-0.4	-0.5	-0.6	0.5	0.7	0.4	0.5	1.0	0.3	0.2	1.5
Blood Eosinophil Count	0.3	2.6	22.9	0.7	0.6	-0.6	-0.7	-0.6	1.7	-1.4	0.1	1.2	1.8	2.5	-0.6	-0.3	-1.1	0.6	-0.1	-1.0	-3.2	1.0	-4.8	0.2	-1.8	-1.4
Blood White Count	0.3	2.2	8.4	-0.6	-1.2	-1.4	-1.3	-0.2	-0.6	-2.5	-0.7	-0.9	-0.7	0.0	-1.8	0.8	-2.1	-1.3	-1.3	-2.4	-1.7	-1.9	-2.9	-2.0	0.6	0.5
Cardiovascular Disease	0.3	1.0	4.7	0.8	-0.8	1.1	1.0	0.6	-0.8	-1.2	0.3	-0.9	-0.1	-0.2	-0.9	1.2	-2.2	-0.3	0.6	-0.4	-0.3	0.3	-1.7	-0.1	1.1	2.1
Lung FVC	0.3	1.7	9.5	0.3	0.5	1.1	1.2	0.6	-0.3	0.8	0.6	0.3	-0.3	-0.6	1.7	0.8	0.8	-1.7	0.9	1.7	1.8	1.3	3.1	1.2	1.8	2.0
Number of treatments/medications taken	0.3	0.6	2.6	1.1	-0.0	0.5	0.4	-1.0	0.2	-1.0	0.8	0.1	0.3	0.4	-0.5	1.5	-0.4	-0.9	0.2	-0.0	1.2	0.4	-0.2	0.5	1.6	0.4
Sensitivity / hurt feelings	0.3	0.6	1.4	0.1	0.5	-0.9	-0.9	-0.9	0.2	-1.0	0.3	0.6	0.5	0.8	-0.7	0.9	0.2	-0.7	-0.4	-1.0	0.7	-1.1	-1.2	-0.7	0.6	-1.0
Ever had hysterectomy (womb removed)	0.3	0.4	1.8	-1.1	-0.1	0.3	0.1	0.1	-0.1	0.4	-0.8	-0.2	-0.2	-0.3	-0.8	-1.1	-1.1	1.4	-0.3	0.1	-0.9	0.0	-0.4	0.3	-0.3	-0.7
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.6	-0.3	-0.4	-0.3	-0.5	-1.3	0.5	-0.9	0.1	-0.1	0.0	0.4	0.1	0.5	-0.6	0.1	-0.3	-0.5	-0.7	0.1	-1.1	-0.3	-0.6	0.4
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.0	0.4	0.3	-0.5	-0.4	-0.2	0.3	-0.7	0.5	0.2	-0.2	0.5	0.7	0.7	-0.3	-0.9	-0.7	-0.9	0.1	-0.6	-0.2	-1.0	-0.6	0.1
Sitting height	0.3	2.2	9.9	-1.6	-1.4	-0.8	-0.7	-0.1	-0.5	-0.1	-1.7	-1.3	-0.7	-0.9	-1.7	-2.4	-0.6	2.1	-1.1	-1.0	-3.1	-1.1	-1.7	-1.2	-2.8	-0.9
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	3.5	0.1	-0.1	0.7	0.6	1.0	0.1	1.0	-0.8	0.2	0.7	0.4	-0.3	-1.3	-0.6	1.9	0.4	0.2	-1.7	0.3	-1.4	0.4	-0.5	-0.5
Trunk fat-free mass	0.3	1.7	4.7	-1.2	-1.8	-0.9	-0.8	0.3	-1.4	0.3	-2.0	-1.4	-1.4	-1.3	-2.2	-2.1	-1.0	0.9	-1.4	-0.8	-1.8	-1.4	-0.5	-1.2	-0.8	-1.2
Noisy workplace	0.3	0.4	2.1	1.0	0.0	0.4	0.4	1.2	-0.9	-0.0	0.1	-0.3	-0.5	-0.6	0.2	0.2	-0.3	-0.8	0.4	0.4	0.2	0.4	1.0	0.3	1.4	0.9
Trunk predicted mass	0.3	1.8	4.9	-1.2	-1.8	-0.9	-0.8	0.3	-1.4	0.3	-2.0	-1.4	-1.4	-1.3	-2.2	-2.1	-1.0	0.9	-1.4	-0.8	-1.8	-1.4	-0.5	-1.2	-0.9	-1.3
Medication: Paracetamol	0.3	0.5	2.4	0.4	0.3	-0.4	-0.4	-1.4	-0.4	-0.0	0.2	0.0	-0.7	-0.4	0.5	0.5	0.2	-1.5	-0.7	0.2	1.5	-0.1	1.5	-0.2	-0.0	0.9
Overall health rating	0.3	0.7	4.3	0.6	-1.0	-0.5	-0.5	-0.5	-0.5	-1.0	-0.4	-0.6	-0.7	-0.1	-1.3	0.7	-1.0	-2.1	-0.9	-1.1	-0.0	-0.6	-1.0	-0.9	0.8	0.4
Supplements: Vitamin C	0.3	0.3	3.1	-0.2	0.1	0.0	0.0	-1.0	0.5	-0.4	-0.0	0.4	0.5	0.8	-0.6	0.6	-0.4	-0.1	-0.1	-0.2	-0.4	0.3	-1.8	-0.0	-1.0	0.6
Hypertension (Self-reported)	0.3	0.7	4.8	0.4	-0.7	1.1	1.1	1.1	-0.4	-0.7	0.5	-0.8	-0.2	-0.2	-0.7	0.5	-2.2	0.1	0.6	0.0	0.1	0.4	-1.2	0.5	0.4	1.9
Back pain experienced in last month	0.3	0.4	2.5	0.2	0.0	0.4	0.3	0.3	0.0	0.4	0.6	0.1	-0.1	-0.1	0.5	1.1	0.7	-1.6	0.3	0.3	1.4	0.5	0.3	0.6	1.3	0.2
Smoking status: Current	0.3	0.6	1.9	-1.0	-1.3	-0.3	-0.3	-0.2	-0.6	-0.9	-0.7	-1.2	-1.0	-0.8	-0.9	0.2	-1.4	-0.9	-0.4	-0.5	0.0	-0.1	-0.2	-0.3	0.3	0.9
Medication: Blood pressure	0.3	0.5	3.4	0.5	-0.8	0.8	0.8	0.9	-0.8	-0.4	-0.0	-1.2	-0.6	-0.8	-0.4	-0.2	-1.8	0.4	0.2	-0.2	-0.6	0.0	-0.3	0.0	0.8	1.0
Medication: Paracetamol	0.3	0.5	4.4	0.1	0.1	-0.1	-0.1	-1.0	-0.9	0.4	-0.2	-0.2	-0.9	-0.8	0.6	-0.3	0.0	0.1	-0.5	0.6	0.8	0.0	2.1	-0.1	-0.2	1.0
Age started oral contraceptive pill	0.3	0.4	4.6	-0.6	-0.1	0.5	0.3	0.1	0.5	0.0	0.1	-0.4	0.2	-0.2	-0.2	-0.8	-0.1	2.1	0.4	-0.1	-0.6	-0.3	-0.3	0.2	-1.0	-0.2
Vascular/heart problems diagnosed by doctor	0.3	0.7	3.8	-0.1	0.8	-1.0	-0.9	-0.7	0.6	0.8	-0.3	0.7	0.0	0.1	1.4	-0.4	1.9	0.0	-0.5	0.3	0.3	-0.1	1.5	-0.1	-0.2	-1.6
Ulcerative Colitis (UC)	0.2	0.5	1.5	0.1	-1.0	-0.6	-0.4	-0.0	-1.0	-0.8	-0.7	-0.5	-0.9	-0.4	-0.7	0.7	-1.2	-1.2	-0.2	-0.2	0.1	-0.0	-0.5	-0.4	0.3	1.0
Triglycerides	0.2	0.3	2.8	-0.2	-0.5	-0.1	-0.1	-0.2	-0.3	-0.7	-0.4	-0.5	-0.3	-0.1	-1.0	-0.3	-1.7	0.2	-0.4	-0.5	-0.6	-0.6	-0.8	-0.2	0.7	-0.5
Frequency of depressed mood in last 2 weeks	0.2	0.2	1.0	0.3	0.6	-0.2	-0.3	0.4	-0.3	-0.7	0.2	0.3	-0.2	0.1	0.5	0.6	-1.0	-0.9	-0.5	-0.3	0.1	-0.4	-0.1	-0.2	0.8	-0.5
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	2.3	0.4	-0.3	-0.1	-0.2	0.4	-0.0	-0.8	0.1	-0.1	0.3	0.2	-1.0	0.4	-0.0	0.0	0.2	-0.6	-0.3	-0.2	-1.5	-0.0	0.6	0.5
Pack years adult smoking proportion	0.2	0.3	1.3	-0.6	0.1	-0.4	-0.5	-0.5	0.5	-0.7	0.1	0.0	0.2	0.5	-0.2	0.5	-0.4	-0.5	-0.4	-0.9	-0.5	-0.3	-1.1	-0.4	0.8	-0.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.2	0.3	0.5	-0.0	-0.3	0.4	-0.4	-0.3	0.5	-0.0	-0.5	-0.2	0.5	0.6	-0.1	-1.1	-0.3	-0.1	0.9	-0.2	1.0	-0.3	0.6	0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	3.5	-0.4	-0.0	-0.2	-0.3	0.1	0.1	0.1	-0.8	0.4	0.6	0.6	-0.5	-0.9	-0.3	1.3	-0.3	-0.5	-1.9	-0.5	-1.2	-0.5	-0.4	-1.3
High blood pressure	0.2	0.7	4.4	0.8	-0.6	1.0	1.0	0.8	-0.3	-0.9	0.6	-0.6	-0.1	-0.0	-0.7	0.8	-2.1	-0.7	0.4	-0.1	0.2	0.3	-1.3	0.3	0.8	1.5
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	1.2	-0.4	0.1	-0.4	-0.4	-1.0	0.2	-0.3	-0.0	-0.3	-0.2	-0.1	0.5	0.0	-1.1	-0.0	-0.6	-0.5	-0.4	-0.5	-0.2	-0.2	-0.4	-0.2
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.7	0.7	-0.2	0.6	0.6	0.4	-0.5	0.3	-0.1	-0.0	0.1	-0.2	-0.8	0.3	-0.2	-0.1	0.5	0.4	0.5	0.0	0.3	0.4	0.9	0.5
Pain all over the body in last month	0.2	0.3	2.4	-0.2	-0.2	-0.2	-0.3	0.1	-0.5	-0.2	-0.0	-0.1	-0.5	-0.0	0.2	0.5	-0.6	-1.5	-0.1	0.1	0.5	0.6	0.2	-0.0	-0.7	1.0
Medication: Ramipril	0.2	0.3	1.3	0.3	-0.9	0.2	0.3	0.1	-0.8	0.3	-0.5	-1.0	-0.7	-0.8	-1.2	-0.4	-1.1	0.4	-0.1	-0.1	0.0	-0.3	-0.0	-0.1	0.6	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	2.0	-0.8	-0.6	0.6	0.7	1.3	-0.7	1.2	-0.8	-0.6	-0.5	-1.1	0.1	-1.0	0.1	-0.0	0.2	0.6	-0.3	-0.0	0.7	-0.0	-1.1	1.4
Standing height	0.2	1.7	5.8	-1.4	-0.6	-1.6	-1.4	-0.8	-0.4	-1.2	-1.2	-0.8	-0.9	-0.5	-0.8	-1.0	-1.5	0.6	-1.8	-1.5	-2.4	-1.6	-1.6	-1.4	-1.0	-2.1
Blood clot in the leg (DVT)	0.2	0.2	1.6	0.2	0.4	-0.2	-0.1	-0.2	0.2	0.2	0.6	0.5	0.4	0.4	0.3	0.6	1.3	-0.4	0.4	0.2	1.1	0.1	0.5	0.1	0.3	0.7
Comparative body size at age 10	0.2	0.6	2.2	-0.0	-0.9	-0.2	-0.4	-0.2	-0.5	0.8	-1.3	-0.7	-0.6	-0.8	-1.1	-1.5	0.2	1.4	-0.8	-0.4	-0.6	-1.1	0.3	-0.8	-1.2	-0.1
Wheeze or whistling in the chest in last year	0.2	0.4	1.6	1.3	0.3	0.9	0.8	0.6	-0.4	0.7	0.2	0.1	0.2	-0.1	0.2	-0.1	-0.2	0.5	0.5	0.7	0.0	0.8	0.7	0.7	1.1	0.3
Medication: Omeprazole	0.2	0.3	1.3	-0.1	-0.4	-0.0	-0.1	-1.0	0.0	-0.5	-0.4	-0.4	-0.3	-0.0	-0.9	-0.5	-1.2	0.3	-0.7	-0.2	-0.6	-0.0	-0.5	0.1	-0.2	-0.6
Illnesses of siblings: Diabetes	0.2	0.3	1.2	0.3	-0.7	-0.3	-0.1	-0.7	-0.4	-0.4	-0.8	-0.6	-0.6	-0.4	-0.7	-0.1	-1.1	0.0	-0.7	-0.5	-0.7	-0.2	0.1	-0.2	0.6	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	3.0	-0.3	0.5	0.1	-0.0	-0.2	0.9	0.5	0.0	0.5	0.6	0.4	0.2	-0.3	0.6	0.9	0.1	0.2	-0.3	-0.2	-1.1	0.3	-1.7	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	1.3	-0.2	0.2	-0.4	-0.4	-0.1	-0.4	0.2	0.1	0.2	-0.4	-0.2	-0.2	0.5	0.3	-1.1	-0.6	-0.3	0.1	-0.6	0.5	-0.8	0.5	-0.4
Friendships satisfaction	0.2	0.3	1.0	0.2	0.3	0.4	0.6	0.8	0.1	1.0	-0.0	0.3	0.6	0.1	0.4	-0.3	0.9	-0.2	0.8	0.7	0.4	0.6	-0.5	0.6	-0.1	-0.1
Commuting to job workplace: Walk	0.2	0.2	0.8	-0.0	-0.2	0.1	0.2	0.5	-0.5	0.3	-0.6	-0.3	-0.2	-0.3	-0.4	-0.9	-0.2	0.8	0.0	0.2	-0.6	0.2	0.4	-0.1	-0.5	0.2
Medication: Gliclazide	0.2	0.2	1.5	-0.7	-0.6	0.0	-0.0	0.2	0.2	-0.3	-0.4	-0.4	-0.0	0.0	-0.9	-0.4	-0.6	0.3	-0.1	-0.3	-0.6	-0.0	-1.2	0.2	-0.1	-0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.3	2.5	-1.6	-0.0	0.1	0.3	0.8	-0.3	0.6	-0.3	-0.1	-0.2	-0.3	0.5	-0.4	-0.0	0.5	0.0	0.1	-0.5	0.0	0.3	-0.2	-1.2	1.2
Guilty feelings	0.2	0.3	1.3	-0.2	-0.3	0.5	0.5	1.1	-0.9	0.1	-0.3	-0.8	-0.7	-0.9	-0.4	-0.1	-0.4	-0.6	0.3	0.3	0.7	-0.1	0.2	0.1	0.5	0.8
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.9	-0.3	-0.4	0.4	0.4	-0.3	-0.1	0.0	-0.3	-0.4	-0.1	-0.2	-0.9	-0.7	-1.0	0.5	-0.1	0.2	-0.5	0.3	-0.3	0.4	-0.4	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	1.7	0.4	0.4	0.0	0.0	-0.2	0.2	0.4	0.6	0.5	0.4	0.3	0.3	0.5	1.3	-0.2	0.4	0.3	1.2	0.1	0.8	0.2	0.2	0.7
Pack years of smoking	0.2	0.3	1.4	-0.3	0.4	-0.2	-0.2	-0.4	0.6	-0.7	0.5	0.2	0.4	0.7	-0.0	0.7	-0.1	-0.5	-0.1	-0.7	-0.4	-0.1	-1.2	-0.3	0.9	-0.6
Blood Red Count	0.1	1.3	10.2	0.8	-0.7	0.7	0.6	0.3	-0.3	-0.9	-0.5	-0.6	0.0	-0.1	-0.2	-0.5	-2.5	1.2	0.6	-0.1	-3.2	1.2	-1.8	0.5	1.5	1.1
Height	0.1	1.2	4.3	-1.3	-0.2	0.4	0.5	1.3	-1.6	0.7	-0.5	-1.3	-1.5	-1.6	0.6	-1.6	-2.1	1.2	-0.2	0.6	-1.4	0.6	0.8	0.3	-1.0	0.4
Townsend deprivation index at recruitment	0.1	0.1	0.6	-0.4	-0.3	-0.2	-0.2	0.1	-0.7	-0.0	-0.4	-0.1	-0.5	-0.3	-0.3	0.3	-0.4	-0.4	-0.4	0.0	-0.1	-0.2	0.6	-0.1	0.8	-0.1
Impedance of arm (right)	0.1	0.6	1.4	-0.6	-0.3	-0.9	-0.8	-1.1	-0.6	-0.9	-0.5	-0.8	-1.1	-0.7	0.2	0.2	-1.2	-0.9	-1.1	-0.7	-0.4	-0.5	0.0	-0.8	-0.6	0.7
Forced expiratory volume in 1-second (FEV1)	0.1	0.4	2.1	-0.9	-0.6	0.1	0.2	0.8	-0.4	1.0	-1.0	-0.5	-0.5	-0.8	-0.1	-1.1	-0.0	0.2	-0.1	0.3	-0.5	-0.2	0.3	-0.1	-1.4	0.8
Impedance of arm (left)	0.1	0.3	1.4	-0.2	0.1	-0.6	-0.5	-1.2	-0.2	-0.8	-0.2	-0.3	-0.5	-0.2	0.2	0.3	-0.9	-0.5	-0.9	-0.8	-0.7	-0.5	-0.6	-0.7	-0.5	0.2
Hair/balding pattern: Pattern 4	0.1	0.3	1.6	0.4	0.2	0.2	0.3	-0.1	0.6	0.1	0.5	0.4	0.9	0.6	-0.4	-0.4	0.7	1.3	0.6	0.4	-0.1	0.5	-1.0	0.7	-0.8	0.2
Eye problems/disorders: None of the above	0.1	0.2	0.8	-0.7	-0.1	-0.2	-0.1	0.0	0.1	0.4	0.1	-0.2	-0.2	-0.2	0.4	-0.0	0.9	-0.5	0.0	0.1	0.7	0.1	0.7	0.0	-0.7	0.5
Comparative height size at age 10	0.1	0.7	4.6	0.6	0.8	-0.4	-0.3	0.0	1.2	-0.8	0.7	1.0	1.2	1.4	0.6	1.1	0.3	-0.2	0.1	-0.7	-0.8	-0.0	-2.1	-0.2	-0.8	-0.8
Commuting to job workplace: Public transport	0.1	0.2	1.0	0.3	0.2	0.2	0.2	-0.0	0.2	0.8	-0.3	0.2	0.2	0.2	0.0	-0.3	-0.2	0.3	0.0	0.4	-0.5	0.6	-0.8	0.4	-1.0	0.4
Diastolic blood pressure, automated reading	0.1	0.2	1.2	1.0	-0.7	0.2	0.1	-0.1	0.2	-0.1	-0.3	-0.2	-0.1	0.0	-0.7	0.1	-1.1	0.1	-0.3	-0.2	-0.5	0.0	-1.1	0.3	0.8	0.1
Impedance of whole body	0.1	0.6	2.6	0.8	1.2	0.0	0.0	-0.9	0.7	-0.8	1.1	0.6	0.4	0.7	1.6	1.6	-0.1	-1.1	0.1	-0.1	0.5	0.5	-0.3	0.3	0.5	0.4
Major Depression (MDD)	0.0	0.0	0.1	-0.0	0.0	0.3	0.0	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.5	1.8	0.8	-0.3	-0.0	0.2	0.6	-1.1	0.7	0.3	-0.7	-1.1	-1.2	-0.1	-0.2	0.1	-1.2	-0.4	0.4	1.3	-0.2	1.1	0.1	0.5	0.5
Tanning	0.0	0.4	2.3	0.2	0.3	0.4	0.1	0.3	0.6	0.8	-0.1	0.3	0.7	0.4	1.0	-0.4	0.5	1.5	0.5	0.2	-0.6	0.3	0.1	0.3	-1.5	0.1
Forced vital capacity (FVC)	0.0	0.2	0.7	-0.4	0.4	-0.5	-0.4	-0.3	0.6	-0.0	-0.1	0.7	0.3	0.4	0.8	0.2	0.4	-0.4	-0.4	-0.2	-0.3	-0.4	0.0	-0.3	-0.6	-0.1
Forced vital capacity (FVC), Best measure	0.0	0.1	0.5	-0.2	0.3	0.1	0.2	0.1	0.1	0.1	-0.0	0.4	0.2	0.0	0.7	0.3	0.2	-0.6	-0.0	0.1	-0.2	-0.2	0.1	-0.1	-0.2	0.6

Hub : Genes

TRPT1

Models

Trait associations