Best TWAS P=2.57e-08 · Best GWAS P=1.97e-07 conditioned to 0.397
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Pancreas | SLC41A1 | 0.24 | 0.21 | lasso | 5 | 0.19 | 1.4e-08 | 5.1 | 5.2 | 2.4e-07 | -0.77 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Prostate | NUCKS1 | 0.38 | 0.23 | lasso | 8 | 0.32 | 7.5e-09 | -5.1 | 5.4 | 7.2e-08 | -0.95 | 0.01 | 0.97 | FALSE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | PM20D1 | 0.22 | 0.26 | lasso | 5 | 0.26 | 1.7e-22 | 4.9 | -5.3 | 1.5e-07 | 0.85 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PM20D1 | 0.24 | 0.37 | lasso | 5 | 0.39 | 4.9e-85 | 5.1 | -5.2 | 1.8e-07 | 0.83 | 0.00 | 1.00 | FALSE |
| 5 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | PM20D1 | 0.19 | 0.25 | lasso | 5 | 0.25 | 3.0e-28 | 5.1 | -5.3 | 8.7e-08 | 0.86 | 0.00 | 1.00 | FALSE |
| 6 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | PM20D1 | 0.29 | 0.35 | enet | 18 | 0.35 | 5.1e-41 | 5.1 | -5.6 | 2.6e-08 | 0.86 | 0.00 | 1.00 | TRUE |
| 7 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | PM20D1 | 0.19 | 0.19 | enet | 4 | 0.19 | 4.5e-11 | 5.1 | -5.2 | 1.8e-07 | 0.81 | 0.00 | 0.99 | FALSE |
| 8 | The Cancer Genome Atlas | Lung Adenocarcinoma | PM20D1 | 0.31 | 0.39 | enet | 16 | 0.41 | 5.1e-52 | 5.1 | -5.2 | 2.2e-07 | 0.82 | 0.00 | 0.99 | FALSE |
| 9 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | PM20D1 | 0.26 | 0.34 | lasso | 3 | 0.34 | 1.9e-40 | 5.1 | -5.3 | 8.6e-08 | 0.88 | 0.00 | 1.00 | FALSE |
| 10 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | PM20D1 | 0.12 | 0.13 | blup | 47 | 0.12 | 9.1e-09 | 5.1 | -5.2 | 2.2e-07 | 0.76 | 0.00 | 1.00 | FALSE |
| 11 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PM20D1 | 0.16 | 0.14 | enet | 15 | 0.16 | 5.6e-16 | 5.1 | -5.5 | 3.6e-08 | 0.90 | 0.00 | 1.00 | FALSE |
| 12 | The Cancer Genome Atlas | Soft Tissue Sarcoma | PM20D1 | 0.23 | 0.24 | lasso | 4 | 0.24 | 1.2e-14 | 5.1 | -5.3 | 1.1e-07 | 0.83 | 0.00 | 1.00 | FALSE |
| 13 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | PM20D1 | 0.17 | 0.11 | lasso | 3 | 0.07 | 5.0e-03 | 5.1 | -5.2 | 1.9e-07 | 0.78 | 0.00 | 0.80 | FALSE |
| 14 | The Cancer Genome Atlas | Stomach Adenocarcinoma | PM20D1 | 0.09 | 0.11 | enet | 6 | 0.10 | 1.3e-07 | -5.2 | -5.2 | 2.2e-07 | 0.96 | 0.00 | 1.00 | FALSE |
| 15 | The Cancer Genome Atlas | Thyroid Carcinoma | PM20D1 | 0.26 | 0.40 | lasso | 4 | 0.41 | 2.0e-42 | 5.1 | -5.2 | 1.9e-07 | 0.82 | 0.00 | 1.00 | FALSE |